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  • Andriantsoa Ranarison Olivier, Yasushi Uda, Sang Woo Bang, Hitoshi Honjo, Motohiro Fukami, Ryo Fukui
    Microbes and Environments
    2006年 21 巻 4 号 216-226
    発行日: 2006年
    公開日: 2007/01/09
    ジャーナル フリー
    The growth and survival of a rifampicin-resistant strain (22R6) of Ralstonia solanacearum were monitored after incorporation of cruciferous plants into infested soil. Air-dried residues of eighteen cruciferous plants (including two amphidiploid lines) were individually added to soil at a rate of 1.6% (w/w) and the water condition maintained at −10 kPa. Within one month of incubation at 24°C, nine of the 18 residues reduced the population of the strain 22R6; B. rapa sp. rapifera `
    Ayumi
    ', Brassica oxyrrhina, and an amphidiploid line of Brassicoraphanus, were most inhibitory. In contrast, total soil bacteria increased, regardless of the nature of the residue. After infested soil was incorporated with cruciferous plant residues and pre-incubated for one month in glasshouse, wilt-susceptible tomato were transplanted and monitored for 34-days on residue-treated soil. The pathogen was detected in shoots of only 2-7% of tomato grown respectively in soil with residue of B. rapa sp. rapifera `
    Ayumi
    ' and Diplotaxis muralis against 47% of tomato in non-residue soil. Data indicated that suppressive effects of the residues might depend on nutritional status and undefined factor in the soil but were not directly dependent on the concentration of glucosinolates (7.2×10-3-1.1×101 μmole g-1 tissue) in the residues and in vitro tests showed that authentic isothiocyanates were inhibitory to the pathogen only at high concentrations (more than 2 μmole g-1 soil).
  • Hisataka Maki, Kana Kubota, Masaru Hatano, Shun Minatsuki, Eisuke Amiya,
    Ayumi
    Yoshizaki, Yoshihide Asano, Hiroyuki Morita, Shinichi Sato, Issei Komuro
    International Heart Journal
    2020年 61 巻 3 号 629
    発行日: 2020/05/30
    公開日: 2020/05/30
    ジャーナル フリー

    The errors in the following list appeared in the article titled "Characteristics of Pulmonary Arterial Hypertension in Patients with Systemic Sclerosis and Anticentriole Autoantibodies" by Hisataka Maki, Kana Kubota, Masaru Hatano, Shun Minatsuki, Eisuke Amiya,

    Ayumi
    Yoshizaki, Yoshihide Asano, Hiroyuki Morita, Shinichi Sato, Issei Komuro (Vol 61, No.2, 413-418, 2020).

  • Morsy Amin Morsy, Kenji Ikeuchi, Masao Ushio, Hideyuki Abe
    Materials Transactions, JIM
    1996年 37 巻 9 号 1511-1517
    発行日: 1996年
    公開日: 2007/06/01
    ジャーナル フリー
    The effects of the bonding temperature and voltage on the rate of the enlargement of intimately contacted area in the anodic bonding of the Kovar alloy to borosilicate glass have been studied systematically in order to obtain better understanding of the rate controlling factor of the process. It was suggested that the attainment of intimate contact was controlled by two factors having different activation energies depending on the bonding temperature. At bonding temperatures higher than 669–687 K (depending on the bonding voltage), the estimated activation energy was close to that of the viscous flow of the glass. At lower bonding temperatures, the estimated activation energy was close to that of the conductivity of the glass. A mechanism of the enlargement of intimately contacted area during the anodic bonding is proposed to explain these results.
  • 井上 幸重, 西部 陽子, 中村 良子
    医化学シンポジウム
    1971年 10 巻 81-84
    発行日: 1971/07/20
    公開日: 2012/11/27
    ジャーナル フリー
    In recent years, there have been many patients in Japan suffering from subacute myelo-optico-neuropathy (SMON) following abdominal disorders. At present, its etiology is not known, however, there are a few kinds of etiological hypotheses. One is that SMON may be a toxicosis caused by oral administration of chinoform, which have many contradictions in explaining the disease. Another is our viral etiological hypothesis, and the present report deals with isolation and some propertiesof the suspect virus present in stools and spinal fluid of SMON patients.
    Virus was isolated, with a high frequency, in BAT-6 cell cultures accompanying a weak and incomplete cytopathic effect (CPE) from feces and spinal fluid of SMON patients living in different prefectures. Attempts to isolate the virus accompanying CPE in HeLa cells, primary monkey kidney cells, and human embryonic kidney cells were all unsuccessful. On the other hand, no virus was isolated in BAT-6 cells from control specimens except the case of aseptic meningitis. Antiserum prepared from the virus isolated from feces neutralized not only the CPE produced by other viruses from stool but also the CPE produced by all viruses from the spinal fluid of SMON patients.
    Neutralizing antibody (NT) titers of 13 among 15 sera collected from SMON patients on different days after the onset of the disease were 5 to 10. In contrast, 10 sera collected from normal adults showed NT titer less than 5. Failure to detect high NT titers in patients sera may explain the subacute course and relapse of the disease. Furthermore, convalescent sera of two cases of aseptic meningitis showed NT titer of 160 to 320. The fact suggests that SMON may be a new viral infection following insufficient immunological state.
    BAT-6 cells were found to be not susceptible to human enteroviruses so far tested, and the virus showed a characteristic host range in tissue culture. The virus was sensitive to ether, and 5-iodo-2'-deoxyuridine. Also, the virus was filtrable through a membrane filter with an average pore size of 220mμ, but the virus was unable to pass through a 100mμ pore filter. Studies on pathogenicity of the virus in mice are revealing that the virus seems to be a new neuropathic slow virus. Further investigations about the properties of the virus are now in progress.
  • リハビリテーション医学
    2006年 43 巻 2 号 79-104
    発行日: 2006/02/18
    公開日: 2010/02/10
    ジャーナル フリー

     
    転倒の要因—ヒトはなぜ転ぶのか—…中馬 孝容 79

    医療機関における転倒予防教室…奥泉 宏康,黒柳 律雄 長谷川 伸,武藤 芳照 長谷川亜弓,太田 美穂 83

    地域における転倒予防の取り組み…高杉紳一郎 87

    入院患者の転倒予防の取り組み…菊地 尚久 91

    エビデンスに基づいた転倒予防…大高 洋平,里宇 明元 96
  • ウイルス学的研究
    森田 盛大, 中尾 亨, 日沼 頼夫
    ウイルス
    1965年 15 巻 1-2 号 23-27
    発行日: 1965年
    公開日: 2010/03/16
    ジャーナル フリー
    An outbreak including aseptic meningitis and acute febrile illness took place in a small village; Wakinosawa, Aomori Prefecture of Northern Japan, between June and August of 1964. Virological and serological studies revealed that the epidemic was caused by Echovirus type 4. Echovirus types 4 was isolated from 7 (16%) of 43 cerebrospinal fluids, 16 (35%) of 46 throat swabs and 41 (43%) of 95 faeces obtained from the patients in acute stage within 6 days after onset. Paired sera of 23 patients, 18 with aseptic meningitis and 5 with acute febrile illness, were examined for heutralizing antibody against the Du Toit strain of Echovirus type 4. In all of them, a significant rise of antibody titer was shown. However, neutralizing antibody titer obtained with the current strain (W-45-64) was much lower than that with the Du Toit strain.
    Outbreaks due to Echovirus type 4 has been reported in many regions of Japan in the summer and fall of 1964 (HINUMA and OHI: Igaku no
    Ayumi
    , 51, 498, 1964) and the outbreak reported here is considered to be comprised in the wide-spread occurrence.
  • 稲村 美希, 吉田 紀子, 小田 知弘, 阿部 智之, 阿部 英之, 楠 勲
    Journal of the Vacuum Society of Japan
    2009年 52 巻 3 号 114-116
    発行日: 2009年
    公開日: 2009/05/28
    ジャーナル フリー
      Si-Si wafer direct bonding was performed by surface activation with Ar ion beam bombardment. The X-ray photoelectron spectroscopy (XPS) spectrum of the Si surface before and after the Ar ion beam bombardment was measured in situ to study the bonding condition quantitatively. The condition of the Ar ion beam bombardment gave the effect for the surface roughness, which was measured by Atom force microscope (AFM). The surface roughness is strongly related to the bonding. The roughness less than Ra=1 nm is necessary for the Si-Si wafer direct bonding.
  • 小田 知弘, 阿部 智之, 楠 勲
    真空
    2006年 49 巻 5 号 310-312
    発行日: 2006年
    公開日: 2007/04/24
    ジャーナル フリー
      Si-Si and quartz-quartz bonded wafers were fabricated using surface activated method by fast atomic beam sputtering. In the Si-Si bonded wafer fabricated by surface activated (dry) method non-bonding area decreased with heating at 300°C under a pressure, though in the Si-Si bonding wafer prepared by H2SO4+H2O2 chemical-treatment non-bonding area increased with heating at 300°C. Gas sealed in the non-bonding area was analyzed with a quadrupole mass spectrometer by cracking the wafer in vacuum. The main species of the gas was water (18 emu). The strength of the bonding between the Si-Si wafers bonded by surface activated method was 20 MPa even at non-heating. This is as strong as the bonding of the Si-Si wafer bonded by heating at 1000°C after H2SO4+H2O2 chemical treatment. The bond strength of the quartz-quartz wafer prepared by surface activation and heating at 700°C is similar to that of the wafer bonded by H2SO4+H2O2 chemical treatment and heating at 700°C.
  • 石原 伸治, 川田 あゆみ, 井上 美保, 渡辺 敏郎, 辻 啓介
    日本食品科学工学会誌
    2007年 54 巻 9 号 412-414
    発行日: 2007/09/15
    公開日: 2007/10/30
    ジャーナル フリー
    正常ラットにおけるカキドオシ抽出物の経口糖負荷試験では,ショ糖負荷30分後から60分後にかけての血糖値で,カキドオシ抽出物群は対照群と比べて有意(p<0.01)な上昇抑制効果を示した.また,ストレプトゾトシン糖尿病ラットにおける経口糖負荷試験では,ショ糖負荷60分後から90分後にかけての血糖値で,カキドオシ抽出物群は対照群と比べて有意(p<0.05)な上昇抑制効果を示した.さらに,カキドオシ抽出物を固相抽出カラムでシリカゲル担体吸着画分と非吸着画分に分けたところ,非吸着画分に血糖値上昇抑制作用が認められた.
  • 小田 佳子, 恵土 孝吉, 三苫 保久
    スポーツ教育学研究
    2002年 22 巻 1 号 13-22
    発行日: 2002/05/31
    公開日: 2010/08/10
    ジャーナル フリー
    This study has the following two aims:
    I) The first is to clarify the process in which inexperienced students in a physical education class acquire the skill of “ken-tai-icchi no datotsu” (striking with the shinai and body).
    II) The second is to clarify the process of acquiring “basic movement” skills by inexperienced subjects of Kendo in preparation for Kendo Club competitions.
    In the physical education class, inexperienced students were taught Kendo for about three months (total 21 hours) using the Edo teaching plan. The following results were obtained;
    1) “Ken-tai-icchi no datotsu” (striking with the shinai and body) times were shortened by 0.01 seconds.
    2) The distance of “fumi-komi” was shortened by 3.7cm.
    3) The time of “datotsu” was shortened by 0.26 seconds.
    4) The lateral spreading of legs and right knee joint angle displayed during the “datotsu” movement demonstrated significant changes (p<0.01). However, the shinai angle and the acceleration did not.
    In the club activity, inexperienced subjects (3 female university students) practiced Kendo about 6 months and were tested on the process of acquiring Kendo skills. The following results were obtained:
    1) “Zenshin-koutai suburi” (the action of swing the shinai with forward and backward footwork) increased by 2.7 times.
    2) The continuous “kote-men” attack was shortened by 0.9 seconds, while the “shikake-men” attack was shortened by 2.1 seconds. The “shikake-kote” attack was shortened by 1.1 seconds, while the “shikake-do” attack was shortened 1.1 seconds, and the “prediction-attack” was shortened by 1.9 seconds.
    3) The distance of “tobi-komi” (including “
    ayumi
    -ashi
    ”) was shortened by a maximum of 38cm and a minimum of 29cm.
  • 渡辺 敏郎, 川田 あゆみ, 井上 美保, 石原 伸治, 辻 啓介
    日本食品科学工学会誌
    2007年 54 巻 9 号 415-418
    発行日: 2007/09/15
    公開日: 2007/10/30
    ジャーナル フリー
    カキドオシ抽出物が本態性高血圧自然発症ラット(SHR)への血圧上昇抑制に対してどのような影響を及ぼすかを検討した.カキドオシ全草から熱水抽出することで収率20%のカキドオシ抽出物を得た.この抽出物には灰分が多く含まれ,特にカリウム(K)含量が高かった.カキドオシ抽出物を飼料中へ5%添加し,28日間SHRに自由摂取させると,試験14日後から対照群に比べて有意に血圧の上昇を抑制した.24時間尿を採尿し,ナトリウム(Na)およびK排泄率を算出したところ,カキドオシ抽出物を摂取することでNaおよびK排泄率ともに有意に増加した.これはカキドオシ抽出物に含まれるKの摂取によりSHRのNa排泄効果を促したことで,血圧上昇抑制作用を示したものと考えられた.
  • Katsuhiro Inoue, Kousuke Kumamaru, Ryuji Yano, Akiko Hayashi,
    Ayumi
    Yamauchi, Shigeaki Matsuoka
    SICE Annual Conference Program and Abstracts
    2002年 2002 巻
    発行日: 2002年
    公開日: 2003/05/15
    会議録・要旨集 フリー
    In this paper, it was investigated that feature extraction method of ERP (Event-Related Potential) under the visual recognition task. First, visual oddball experiments were executed. We examined obtained response EEG about amplitude characteristic, frequency characteristic, and pattern recognition based on AR model. It is confirmed that our method was effective and optimal locations of electrode were occipital by the experiment.
  • 磯部 孝彦, 大崎 愛弓, 長田 久美子
    YAKUGAKU ZASSHI
    2002年 122 巻 4 号 291-294
    発行日: 2002/04/01
    公開日: 2003/02/18
    ジャーナル フリー
    Four known compounds have been isolated from the aerial parts of the Brazilian medicinal plant Pariparoba (Pothomorphe umbellata). They were an alkaloid, a flavone, a dihydrocalcone, and a steroid. The chemical structures were established to be N-benzoylmescaline, wogonin, uvangoletin, and β-sitosterol glucoside using spectral methods. Among these compounds, the main component N-benzoylmescaline showed significant antibacterial activity against Helicobacter pylori.
  • AYUMI
    TAKEMOTO, MOTOYOSHI ODA
    Paleontological Research
    1997年 1 巻 4 号 291-310
    発行日: 1997/12/30
    公開日: 2008/02/01
    ジャーナル フリー
    Factor analysis of planktic foraminiferal assemblages analyzed in sediment samples from the Northwest Pacific Ocean near Japan defines five major factors including the Kuroshio, Transitional Water, Oyashio, Kuroshio Gyre Margin and Coastal Water factors which, when mapped, show distinctive distributions. These factors account for over 94% of the total variance. Each of the factors can be treated as an independent variable in a regression analysis. Equations relating factors to winter and summer sea-surface temperatures (SSTs) show a high degree of accuracy. The standard errors of estimate for the transfer function equations PFJ-125 established in this study average about ±1.75°C for estimated winter temperatures, and about ±1.17°C for summer temperatures. Transfer functions PFJ-125 were applied to assemblages representing the last 12K yrs. in piston core C-1 collected in the area off Joban, northeast Honshu, Japan. The lowest estimated winter SST is 4.1°C and 18.5°C for the summer SST at 10, 500 yrs. B. P. whereas at 6, 300 yrs. B. P. the winter highest SST is 12.8°C and 23.9°C in the summer. Based on down-core variations in estimated winter and summer SST and fluctuations of the five identified factor loadings, the C-1 core site was alternatively under the influence of the Oyashio and Kuroshio Fronts through the last 12 K yrs. Marine conditions at core site C-1 at 10, 500 yrs. B. P. are comparable with those recorded in the same area for the last glacial maximum.
  • 坂口 修平
    YAKUGAKU ZASSHI
    2004年 124 巻 2 号 69-87
    発行日: 2004/02/01
    公開日: 2004/01/28
    ジャーナル フリー
      Despite the remarkable progress in intensive care medicine, sepsis and shock continue to be major clinical problems in intensive care units. Septic shock may be associated with a toxic state initiated by the stimulation of monocytes by bacterial toxins such as endotoxin, which is released into the bloodstream. This study describes the role of oxidative stress in endotoxin-induced metabolic disorders. We demonstrate that endotoxin injection results in lipid peroxide formation and membrane injury in experimental animals, causing decreased levels of free radical scavengers or quenchers. Interestingly, it was also suggested that tumor necrosis factor (TNF)-induced oxidative stress occurs as a result of bacterial or endotoxin translocation under conditions of reduced reticuloendothelial system function in various disease states. In addition, we suggest that intracellular Ca2+, Zn2+, or selenium levels may participate, at least in part, in the oxidative stress during endotoxemia. On the other hand, it is also suggested that the extent of endotoxin-induced nitric oxide (NO) formation may be due, at least in part, to a change in heme metabolic regulation during endotoxemia. However, in our experimental model, NO is not crucial for lipid peroxide formation during endotoxemia. Sho-saiko-to is one of the most frequently prescribed Kampo medicines and has primarily been used to treat chronic hepatitis. We report that Sho-saiko-to decreases the rh TNF-induced lethality in galactosamine-hypersensitized mice and protects mice against oxygen toxicity and Ca2+ overload in the cytoplasm or mitochondria during endotoxemia. We further suggest that Sho-saiko-to shows a suppressive effect on NO generation in macrophages stimulated with endotoxin and that it may be useful in improving endotoxin shock symptoms.
  • 井野 よし子, 戎 一郎, 池田 博, 月見 一平
    太成学院大学紀要
    2021年 23 巻 89-97
    発行日: 2021年
    公開日: 2021/06/16
    研究報告書・技術報告書 オープンアクセス
    演劇活動「民話の会夢の船」は,住民の出会いと交流を促進する目的で,大阪府柏原市に在住する社会福祉法人旭丘まぶね保育園小規模型子育て支援センターの活動の一環として,住民とともに地域の伝承・昔話を生かした演劇活動を展開している。この演劇活動が19年余り経過したことを機に,さらなる展開を目指してこれまでの活動について紹介・報告する。
  • 松原 亜由美, 杉原 利治
    一般社団法人日本家政学会研究発表要旨集
    2002年 54 巻
    発行日: 2002/06/01
    公開日: 2003/07/29
    会議録・要旨集 フリー
    疎水基を二本もつ陽イオン界面活性剤、ジアルキルジメチルアンモニウム塩(DADA)の毛髪への吸着を研究した。DADAの吸着量は毛髪の種類、共存する界面活性剤の有無及び種類、濃度、温度に依存した。ポリオキシエチレン系非イオン界面活性剤が存在すると毛髪へのDADAの吸着量は減少し、疎水基が長いものほどその効果が大きかった。また、DADAのアルキル炭素鎖数の違いも顕著であり、アルキル炭素数が20のDDeDAはアルキル炭素数24のDDoDAより吸着量が多かった。また、DDeDAの吸着挙動は、疎水基が一本であるトリメチルステアリルアンモニウムクロリド(TSAC)と類似しており、DDoDAの挙動がむしろ特殊であることがわかった。
  • 藤澤 宏幸
    理学療法の歩み
    2023年 34 巻 1 号 8-13
    発行日: 2023年
    公開日: 2023/05/01
    ジャーナル フリー

    理学療法は,疾病治療とリハビリテーション医療における社会復帰支援のための動作の再建を通して,国民の健康・福祉に貢献している。その成熟を図るためには,哲学・倫理レベル,パラダイム・理論レベル,実践レベルの各階層で議論が必要である。臨床に直結する実践レベルにおいては,臨床研究が進められているものの,パラダイム・理論レベルにおいては議論が十分とはいえない。その意味で,理学療法モデルの構築が課題としてあるが,2000年に国際障害分類試案から国際生活機能分類へ移行した際に,理学療法の治療モデルとしていた機能障害-能力低下-社会的不利の因果モデルは臨床では用いられなくなった。国際生活機能分類における生活機能モデルは専門職間の共通言語としては有用と考えられるが,それに連結できる理学療法モデルが必要であり,その一つに行動制約モデルがある。行動制約モデルは運動行動の階層性に基づいたものであり,行為を射程に入れた動作の再建という意味では有用であるが,疾病治療のためのモデルとしては不足しているところがある。そこで,本論では,理学療法を考えるうえでの疾病の捉え方を,病因,病理,機能不全・機能障害の循環的な関係性によって整理し,疾病治療における理学療法モデルの位置づけを検討する。

  • 照井 佳乃
    理学療法の歩み
    2023年 34 巻 1 号 3-7
    発行日: 2023年
    公開日: 2023/05/01
    ジャーナル フリー

    脳卒中患者の中には,肺炎を発症する者や拘束性換気障害が生じる者がいる。脳卒中患者の呼吸に対する介入は,肺炎予防で実施されることが多いものの,近年,呼吸筋トレーニングが運動耐容能の改善に有効であることが示されつつある。本論文では,1.人工呼吸器使用中や不顕性誤嚥による肺炎の予防,2.拘束性換気障害,3.呼吸筋筋力低下と呼吸筋トレーニング,4.呼吸機能・呼吸筋力と歩行パラメータについて紹介する。4.呼吸機能・呼吸筋力と歩行パラメータの関連については,著者らが進めている研究であり,歩行パラメータは特に左右非対称性に着目している。呼吸筋トレーニングは専用のデバイスを用いることで臥位や座位でも実施でき,運動耐容能の改善が期待できることから,転倒リスクの少ない自主トレーニングに使用できると考える。今後更なる検討が必要であるものの,本論文が脳卒中患者に呼吸筋トレーニングの実施することを検討する一つのきっかけになればと考える。

  • 澤邉 泰, 髙橋 伸吾, 佐々木 雄太, 沼澤 由佳子
    理学療法の歩み
    2023年 34 巻 1 号 27-29
    発行日: 2023年
    公開日: 2023/05/01
    ジャーナル フリー
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