Confusion
often occurs in acute brain infarction, but its character and effective therapy have not been examined well. We divided 49 patients with acute brain infarction into the
confusion
group (20 patients) and the non-
confusion
group (29), and compared the character of each group. The
confusion
group showed older age (79±2 years old vs. 72±2, p=0.0075) and lower scores of Hasegawa Dementia Scale (15.3±1.8 vs. 21.2±2.1, p=0.0183) than the non-
confusion
group. Right hemisphere lesions, especially the front-parietal lesions, were more often observed in the
confusion
group. Four of 5 patients who did not receive pharmacotherapy and only 7 of 15 patients who received pharmacotherapy, recovered from
confusion
. On the other hand, recovery from
confusion
was quicker in patients with pharmacotherapy than without pharmacotherapy. Patients with
confusion
stayed significantly longer in the hospital (72.9±11.3 days vs. 48.9±6.2, p < 0.05) and modified Rankin Scale was significantly higher in patients without
confusion
(2.6±0.3 vs. 1.9±0.3, p<0.05). According to these results, patients with
confusion
showed poorer outcome. We need to establish effective therapies against
confusion
in acute brain infarction.
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