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全文: "Inferior parietal lobule"
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  • 宇野 富徳, 王 力群, 三分一 史和, 外池 光雄, 金田 輝男
    生体医工学
    2010年 48 巻 1 号 59-65
    発行日: 2010/02/10
    公開日: 2010/11/17
    ジャーナル フリー
    We investigated the olfactory “Kansei” information processing for two kinds of smells by measuring the brain activities associated with olfactory responses in humans. In this study, the brain activities related to discrimination and recognition of odors were examined using functional magnetic resonance imaging (fMRI). In experiment 1, odor stimuli (lemon-like and banana-like) were presented using a block design in a blinded manner, and the kind of fruits was identified by its odor. The frontal and temporal lobe, inferior parietal lobule, cingulate gyrus, amygdaloid body and parahippocampal gyrus were primarily activated by each odor based on conjunction analysis. In experiment 2, as a result of performing an oddball experiment using the odors of experiment 1, the active areas were mainly found in the temporal lobe, superior and inferior parietal lobule, insula, thalamus, supramarginal gyrus, uncus and parahippocampal gyrus. Moreover, these regions overlapped with the emotional circuit. These experimental results suggest that common brain activities accompany the discrimination and cognition associated with odor stimuli, which may underlie the olfactory responses relevant to the higher brain function and emotions associated with olfactory function.
  • Yuzuru YASUDA, Toshiyuki WATANABE, Akira OGURA
    Internal Medicine
    2000年 39 巻 12 号 1105-1107
    発行日: 2000年
    公開日: 2006/03/27
    ジャーナル フリー
    Cheiro-oral syndrome due to a parietal lesion has been reported in conjuction with a brain tumor, infarction and migraine. Only six reports of cheiro-oral syndrome due to a parietal infarction have been reported to date. We treated a 45-year-old woman with cheiro-oral syndrome due to a parietal infarction. Her sensory disturbance was characterized by paresthesia in the lower face and hand on the left side, and severe involvement of stereognosis and graphesthesia in the left hand. The pathogenesis of parietal cheiro-oral syndrome is discussed.
    (Internal Medicine 39: 1105-1107, 2000)
  • Tsubasa Oikawa, Daisuke Hirano, Takamichi Taniguchi, Hitoshi Maruyama
    Journal of Physical Therapy Science
    2017年 29 巻 4 号 702-706
    発行日: 2017年
    公開日: 2017/04/20
    ジャーナル フリー

    [Purpose] The purpose of this study is to assess the influence of tool holding on brain activities during motor imagery in two tasks: imagining the movement of writing the alphabet while holding a pen and without holding the pen. [Subjects and Methods] Eleven healthy right-handed adults performed two tasks, holding a pen and not holding the pen during imagining the movement of writing the alphabet using a pen. Regions of targets were Brodmann areas 6 which were a motor-related region, 44/45 and 39/40 which taken on the role of forming the body schema. Change of the oxygenation state of hemoglobin associated with brain activity were acquired using a near-infrared spectroscopy. [Results] When using their dominant right hands, task-related increases in oxy-Hb were prominent in Brodmann areas 44/45 and 39/40 when imagining writing while actually holding the pen than when not. When using the non-dominant left hands, there were no significant differences between the two conditions in the same areas. [Conclusion] These results suggest that the tool held can be incorporated into the body schema in the motor imagery of an automated tool use task. Therefore, tool holding during motor imagery might be more effectively influence during rehabilitation.

  • Tatsunori Ikemoto, Takahiro Ushida, Shigeki Tanaka, Kazuo Morio, S. Vadim Zinchuk, Toshikazu Tani, Shinichirou Taniguchi, Akio Ushida
    PAIN RESEARCH
    2003年 18 巻 3 号 137-144
    発行日: 2003/09/30
    公開日: 2014/04/02
    ジャーナル フリー
       We employed functional magneto-resonance imaging to compare the pattern of brain activation evoked by painful and non-painful mechanical stimulation in normal volunteers and patients with neuropathic pain. Stimulation was performed using von Frey filaments. In normal volunteers, painful stimulation caused significant activation in the inferior parietal lobule (area 40), primary motor area (area 4), cingulate gyrus (area 24/31), middle temporal Gyrus (area 21/37), thalamus, and cerebellum. In the non-pain condition, SI, parietal lobule and frontal lobe were activated. In the patients, stimulation in the area of allodynia, in the non-pain condition elicited painful feelings and caused a wider area of activity when compared to the area of activity when the palm of unaffected side was stimulated. The activation was promoted in the frontal and occipital lobes, cingulate gyrus, and cerebellum. These findings suggest that neuropathic pain patients exhibit differences in the pain perception that may reflect chronical activation of the appropriate functional brain areas.
  • 杉森 絵里子, ミッシェル カレン, レイ キャロル, グリーン エリック, ジョンソン マーシャ
    日本認知心理学会発表論文集
    2013年 2013 巻 O2-3
    発行日: 2013年
    公開日: 2013/11/05
    会議録・要旨集 フリー
    fMRIを用いて、聴覚情報のリアリティモニタリングについて検討した。まずはスキャナーの中で、他者の声で単語を聞かせるか、聞いているところを想像させた。その後スキャナーの外で、各単語について、見たか想像したか未学習の中から選択させた。①想像させた単語に関しては、左中前頭回(BA6)がより活性化した場合は「聞いた」と誤判断するよりも「想像した」と正判断することが、②想像させた場合にも聞かせた場合にも、左下前頭回(BA45,44)がより活性化した場合は「想像した」よりも「聞いた」と判断することが明らかになった。さらに、想像させた単語について「聞いた」と誤判断した単語について、幻聴様体験尺度のスコアと上側頭回(BA22)の活性化に正の相関がみられた。これらの脳活動により、ソースモニタリング時に認知操作情報(中前頭回)と知覚情報(左下前頭回、上側頭回)が使用されていることが示唆された。
  • Noriko Kimura, Akira Ichinose, Takumi Matsumura, Satoshi Suzuki
    Journal of Signal Processing
    2015年 19 巻 4 号 167-170
    発行日: 2015/07/30
    公開日: 2015/07/30
    ジャーナル フリー
    As one of the various brain functions, an extension of the body image called the body schema (BS) is known. The BS is required to recognize the positions of our body parts and limbs. To utilize the BS, it is necessary to effectively integrate visual information and haptic information. An extension of the BS often occurs in our daily lives where we use a tool or device by hand; hence, the BS also related to the operational skill of vehicles because the feeling of the car width is an extension of the BS itself. With this background, in our previous study, a lanekeeping assistive method using a weak electrical stimulus based on the consideration of BS extension conditions was presented. It was confirmed in that study that the driving skill was improved using this method through experimental verification using a driving simulator. The induction of the BS extension by the external stimulus was, however, not shown directly in the simulator experiment. Therefore, in this paper, characteristic evidence of the BS extension was investigated from biosignal in the brain measured by near-infrared spectroscopy (NIRS). We monitored the cerebral blood flow (CBF) around the inferior parietal lobule, which is related to the BS. As a result, a significant (p<0.1; Wilcoxon rank-sum) characteristic pattern in the CBF variation was found for all four participants.
  • 劉 涛
    認知科学
    2013年 20 巻 2 号 275-276
    発行日: 2013年
    公開日: 2014/11/28
    ジャーナル フリー
  • 劉 涛, 齋藤 洋典, 大井 京
    日本認知心理学会発表論文集
    2013年 2013 巻 O1-7
    発行日: 2013年
    公開日: 2013/11/05
    会議録・要旨集 フリー
    The present study examined the neural mechanisms underlying the inter-brain processing during cooperation in a two-person computer game. We simultaneously measured pairs of participants’ fronto-parietal activations during the game using near-infrared spectroscopy (NIRS). One participant’s task was to build a target pattern by placing disks on a monitor as a builder, while another helped (cooperation) or disrupted (competition) the builder’s process as a companion. The NIRS data demonstrated two findings: (1) The builder showed higher activation in the right inferior frontal gyrus (IFG) under the cooperation condition than under the competition condition, while the companion showed a reversed pattern. (2) The right IFG activations of the builder-companion pairs showed a positive inter-brain correlation under the cooperation condition. These results suggest that the leading player is actively engaged in achieving a goal regardless of task type, but the inter-brain synchronization emerges only during cooperation as their shared attention and/or empathic processing.
  • 宇野 彰, 春原 則子, 金子 真人, 粟屋 徳子, 片野 晶子, 狐塚 順子, 後藤 多可志, 蔦森 英史, 三盃 亜美
    音声言語医学
    2010年 51 巻 3 号 245-251
    発行日: 2010年
    公開日: 2010/08/31
    ジャーナル フリー
    本研究の目的は, 発達性ディスレクシア (DD) と後天性の大脳損傷によって生じる失読失書例との共通点と相違点について要素的認知機能の発達や局在化に関して検討することである. DD群は10名の右手利き例である. 失読失書例は右利きの男児2名である. 失読失書症例KYは8歳にてモヤモヤ病術後, 脳梗塞にて軽度失語症を発症し, その後軽微な失語症とともに失読, 失書症状が認められた発症半年後から追跡している症例である. 症例MSは, 8歳時の脳梗塞により健忘失語が観察された10年以上追跡してきている現在21歳の症例である. いずれも, 失語症状は軽微で失読失書症状が中心となる症状であった. SLTAではDD群, 失読失書例ともに読み書きに関連する項目以外は定型発達児群と差がなく音声言語にかかわる項目は正常域であった. DD群における局所血流低下部位は左下頭頂小葉を含む, 側頭頭頂葉結合領域であった. また, 機能的MRIを用いた実験により, 左下頭頂小葉にある縁上回の賦活量に関して典型発達群と比較して異なる部位であった. 一方, 失読失書2例における共通の大脳の損傷部位は左下頭頂小葉であった. DD群ではROCFT (Rey-Osterrieth Complex Figure Test) において遅延再生得点が平均の-1SDよりも得点が少なかったが, 失読失書2例においてはともに得点低下はなかった. 一方, 発達性ディスレクシアと後天性失読の大脳機能低下部位は類似していたが, 非言語的図形の処理能力は, 発達性ディスレクシア群で低く, 後天性失読例では保たれていた. 後天性言語的図形である文字と非言語的図形の処理は, 少なくとも8歳までの発達途上で機能が分離されてきているように思われた.
  • Hao Chen, Su Chen, Lidan Zeng, Lin Zhou, Shengtao Hou
    BioScience Trends
    2014年 8 巻 5 号 286-289
    発行日: 2014/10/31
    公開日: 2014/11/08
    ジャーナル フリー
    Albert Einstein's brain has long been an object of fascination to both neuroscience specialists and the general public. However, without records of advanced neuro-imaging of his brain, conclusions regarding Einstein's extraordinary cognitive capabilities can only be drawn based on the unique external features of his brain and through comparison of the external features with those of other human brain samples. The recent discovery of 14 previously unpublished photographs of Einstein's brain taken at unconventional angles by Dr. Thomas Stoltz Harvey, the pathologist, ignited a renewed frenzy about clues to explain Einstein's genius. Dr. Dean Falk and her colleagues, in their landmark paper published in Brain (2013; 136:1304-1327), described in such details about the unusual features of Einstein's brain, which shed new light on Einstein's intelligence. In this article, we ask what are the unique structures of his brain? What can we learn from this new information? Can we really explain his extraordinary cognitive capabilities based on these unique brain structures? We conclude that studying the brain of a remarkable person like Albert Einstein indeed provides us a better example to comprehensively appreciate the relationship between brain structures and advanced cognitive functions. However, caution must be exercised so as not to over-interpret his intelligence solely based on the understanding of the surface structures of his brain.
  • 深見 忠典, 島田 尊正, 赤塚 孝雄, 斎藤 陽一
    電気学会論文誌C(電子・情報・システム部門誌)
    2004年 124 巻 9 号 1692-1697
    発行日: 2004年
    公開日: 2004/12/01
    ジャーナル フリー
    In audiometry, ABR (Auditory Brainstem Response) is widely used. However, it shows low accuracy in low frequency band. Meanwhile, AMFR (Amplitude-Modulation-Following Response), the response during hearing an amplitude-modulated tone, has high frequency specificity and is brought to attention. As the first step to clinical application of AMFR, we investigated the activated areas in a brain when the subjects hear SAM tone (Sinusoidally Amplitude-Modulated tone) with both ears. We measured following two signals. One is the difference of BOLD (Blood Oxygenation Level Dependent) signal between hearing SAM tone vs. silence, the other is the difference of BOLD signal between hearing SAM tone vs. unmodulated tone. As a result, in the case of SAM vs. silence, the bilaterally auditory cortex (Broadmann Area 41, 42), the biratelally BA 10, left superior frontal gyrus and right superior temporal gyrus were activated (p<0.0037, uncorrected).
    In the case of SAM vs. unmodulated tone, the bilaterally superior frontal gyrus (BA 6) and precuneus (BA 7), neighboring area including the bilaterally inferior parietal lobule (BA 40), the bilaterally medial frontal gyrus and superior frontal gyrus were activated (p<0.021, uncorrected). Activations of visual perception due to eye-opened state were detected in some parts of activations.
    As a result, we inferred that modulated tone was recognized in the medial frontal gyrus and inferior parietal lobule was the part related to perception of amplitude-modulation.
  • 中尾 善明, 高田橋 篤史, 鎗田 勝, 藤元 登四郎, 田村 俊世
    生体医工学
    2011年 49 巻 6 号 805-814
    発行日: 2011/12/10
    公開日: 2012/04/10
    ジャーナル フリー
    Remarkable progress in cognitive neuroscience has revealed the involvement of the prefrontal cortex and the orbitofrontal cortex in human working memory, but the orbitofrontal cortex is still one of the least understood regions in the human brain. To elucidate the contribution of the orbitofrontal cortex to human working memory, we studied EEG P300 activity in n-back task. We elicited early P3 around 300 ms and late P3 around 360 ms of P300 components in n-back ERP. The amplitudes of the respective peaks changed depending on the working memory load (0-back, 1-back, 2-back, 3-back). We used source analysis to evaluate the orbitofrontal cortex in P3 components. A source model was constructed with the sources seeded from fMRI meta-analysis of n-back task and additional sources in the orbitofrontal cortex and the visual cortex estimated with P100 and late P3 components in the n-back ERP. This source model had more than 99% of GOF (goodness of fit) in n-back ERP. It gave us an insight of brain activity at the positions where sources existed. Early P3 was mainly produced by the dorsolateral prefrontal cortex, the ventrolateral prefrontal cortex, the inferior parietal lobule, the medial posterior parietal and the visual cortex. Late P3 was mainly produced by the medial premotor, the lateral premotor, the frontal pole and the orbitofrontal cortex. The contribution of the frontal pole and the orbitofrontal cortex had peaks around 390 ms which were later than late P3 component. In this study, the method to evaluate the orbitofrontal cortex activity in n-back ERP was provided. Our results elicited the involvement of the orbitofrontal cortex in late P3 component of n-back ERP.
  • Yasuhiro Funakoshi, Masafumi Harada, Hideki Otsuka, Kenji Mori, Hiromichi Ito, Takashi Iwanaga
    The Journal of Medical Investigation
    2016年 63 巻 3.4 号 204-208
    発行日: 2016年
    公開日: 2016/09/17
    ジャーナル フリー

    Purpose: The purpose of this study was to investigate changes in the functional connectivity of the default mode network (DMN) in normal aging and in children with autistic spectrum disorder (ASD) by using resting-state functional magnetic resonance imaging (rsfMRI) and independent component analysis. Methods: Thirty-one healthy controls (HC) in four age groups (1-3, 4-8, 20-29, and 50-59 years) and 14 childhood ASD cases (1-8 years of age) were examined by rsfMRI echo-planar imaging on a clinical 3-T MRI scanner. Imaging of all children (1-8 years) was conducted under sedation, while adults were scanned in the awake state with eyes closed. Results: The regions of DMN functional connectivity in the bilateral inferior parietal lobule and posterior cingulate cortex were smaller in HC children than in HC adults, and smaller in the ASD group than in the HC children. Conclusion: It is possible to observe developmental and pathological changes in the DMN by rsfMRI. Reduced DMN functional connectivity in children may be a useful biomarker for ASD diagnosis. J. Med. Invest. 63: 204-208, August, 2016

  • Kosuke ITOH, Yukihiko FUJII, Ingrid L. KWEE, Tsutomu NAKADA
    Magnetic Resonance in Medical Sciences
    2005年 4 巻 2 号 69-74
    発行日: 2005年
    公開日: 2005/12/06
    ジャーナル オープンアクセス
    While activity of MT+/V5 neurons is believed to be necessary for the conscious perception of visual motion, whether neural activity in MT+/V5 is a sufficient condition for the conscious perception of motion in vision still remains unanswered. A high-field (3.0 Tesla) functional magnetic resonance imaging (fMRI) study was designed and performed to answer this specific question. Eleven healthy subjects viewed a checkerboard pattern stimulus reversed in contrast at 0.2, 12, 30, and 60 Hz while being probed for activation in MT+/V5. At 0.2 Hz, all viewers perceived pattern-reversal which was stationary in position. However, at 12, 30, and 60 Hz, many subjects perceived apparent motion (e.g., vertical and horizontal flows) in the square pattern. At 12 and 30 Hz reversals, MT+/V5 was activated in all subjects (11/11). Nevertheless, three out of eleven (3/11) subjects denied motion perception in these conditions. At 60 Hz reversal, as many as seven out of eleven (7/11) subjects failed to see motion but activation in MT+/V5 was found in the majority (5/7) of the subjects. The results demonstrated that significant MT+/V5 activation occurs without accompanying subjective awareness of seeing motion in an apparent-motion stimulus, indicating that neural activity in MT+/V5 does not represent a sufficient condition for conscious perception of motion in vision.
  • 細見 晃一, 清水 豪士, 圓尾 知之, 渡邉 嘉之, Ming Koo Hui, 谷 直樹, 後藤 雄子, 貴島 晴彦, 吉峰 俊樹, 齋藤 洋一
    PAIN RESEARCH
    2015年 30 巻 3 号 173-176
    発行日: 2015/08/10
    公開日: 2015/08/18
    ジャーナル フリー
       We have previously reported the efficacy of 5 Hz repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex (M1) in relief of central post–stroke pain (CPSP). The objective of this study was to explore changes of functional connectivity related to CPSP condition, and to assess changes of functional connectivity induced by rTMS in patients with CPSP. In 14 patients with CPSP and 14 control subjects, resting–state functional MRI were taken. Twelve of these patients received 5 Hz–rTMS of M1, and underwent resting–state functional MRI before and after rTMS. Functional connectivity associated with motor and default mode networks increased in patients with CPSP compared with control subjects. Moreover, functional connectivity associated with default mode network and anterior cingulate cortex decreased after rTMS. These findings suggest that several functional networks are involved in pathophysiology of CPSP and mechanisms of action of rTMS.
  • Yukiko Nota, Kiyoshi Honda
    Acoustical Science and Technology
    2004年 25 巻 4 号 286-289
    発行日: 2004年
    公開日: 2004/07/01
    ジャーナル フリー
  • KyeongMi Kim
    Journal of Physical Therapy Science
    2015年 27 巻 10 号 3315-3317
    発行日: 2015年
    公開日: 2015/10/30
    ジャーナル フリー
    [Purpose] The purpose of this study was to suggest evidenced information about action observation to improve upper limb function after stroke. [Methods] A systematic review of randomized controlled trials involving adults aged 18 years or over and including descriptions of action observation for improving upper limb function was undertaken. Electronic databases were searched, including MEDLINE, CINAHL, and PEDro (the Physiotherapy Evidence Database), for articles published between 2000 to 2014. Following completion of the searches, two reviewers independently assessed the trials and extracted data using a data extraction form. The same two reviewers independently documented the methodological quality of the trials by using the PEDro scale. [Results] Five randomized controlled trials were ultimately included in this review, and four of them (80%) reported statistically significant effects for motor recovery of upper limb using action observation intervention in between groups. [Conclusion] This review of the literature presents evidence attesting to the benefits conferred on stroke patints resulting from participation in an action observation intervention. The body of literature in this field is growing steadily. Further work needs to be done to evaluate the evidence for different conditions after stroke and different duration of intervention.
  • 中尾 雄太, 大西 英雄, 遠藤 優有美, 城本 修, 村中 博幸
    音声言語医学
    2014年 55 巻 2 号 146-154
    発行日: 2014年
    公開日: 2014/05/28
    ジャーナル フリー
    われわれは,音刺激への注意喚起における脳賦活領域を同定するために,fMRI(functional magnetic resonance imaging)を用いて,「聴く」と「聞く」における脳賦活領域を定量的に比較検討した.さらに,自作したソフトウェアを用いてMR画像の賦活領域の体積を算出し,各領域における賦活程度を比較した.聴覚障害を認めない健常成人12名(男性5名,女性7名)に対して,男性話者と女性話者の単音節聴取課題,雑音下聴取課題を行った.その結果,音刺激へ注意を喚起すると,前頭前野,縁上野,帯状回が賦活することが示唆された.また,同性話者より異性話者の声に注意を喚起したほうの脳活動が活発になると示唆された.
  • 松田 雅弘, 渡邉 修, 来間 弘展, 村上 仁之, 渡邊 塁, 妹尾 淳史, 米本 恭三
    理学療法科学
    2011年 26 巻 1 号 117-122
    発行日: 2011年
    公開日: 2011/03/31
    ジャーナル フリー
    〔目的〕脳卒中により利き手側の片麻痺を呈した場合,利き手交換練習を行うことが多い。そのため健常者における非利き手での箸操作の運動時,イメージ時,模倣時の脳神経活動を明らかにした。〔対象〕神経学的な疾患の既往のない右利き健常成人5名(平均年齢20.7歳)とした。〔方法〕課題は,左手箸操作運動課題,左手箸操作イメージ課題,左手箸操作の映像をみながら箸操作運動課題(模倣課題)の3種類とし,その間の脳内活動を3.0T MRI装置にて撮像した。〔結果〕運動課題では左右感覚運動野・補足運動野・小脳・下頭頂小葉・基底核・右Brodmann area 44が賦活した。イメージ課題では,運動課題と比べ左感覚運動野・小脳の賦活が消失していた。模倣課題では,左右感覚運動野・補足運動野・上下頭頂小葉・Brodmann area 44が賦活した。〔結語〕イメージ課題と模倣課題には,運動課題時に賦活する領域を両課題とも補う傾向にあることから,箸操作訓練の際には運動課題のみではなく両者を取り入れて行う意味があることが示唆された。
  • TAKASHI YAMADORI, KOICHI SUKEKAWA, TAKEHIKO UMETANI, ATSUSHI YAMADORI
    Okajimas Folia Anatomica Japonica
    1982年 58 巻 4-6 号 627-633
    発行日: 1982年
    公開日: 2012/09/24
    ジャーナル フリー
    To determine the difference of size between the cortical speech region in the dominant hemisphere and its corresponding region in the other hemisphere, the planum temporale was measured and compared by means of a rubbed copy method using 50 brains of both sexes. The planum temporale was significantly larger in the left hemisphere than in the right.
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