詳細検索結果
以下の条件での結果を表示する: 検索条件を変更
クエリ検索: "TiA"
12,970件中 1-20の結果を表示しています
  • 入野 忠芳, 菊池 晴彦
    脳卒中の外科研究会講演集
    1979年 8 巻 198-202
    発行日: 1979年
    公開日: 2012/10/29
    ジャーナル フリー
    For the 106
    TIA
    cases (86 nonsurgical cases and 20 surgical cases), the recurrence ratio of repeated
    TIA
    and/or newly developed completed stroke was compared each other among nonsurgical cases and also between surgical and nonsurgical cases with reference to the angiographically demonstrated cerebral arterial lesion. In addition, the recurrence ratio of the nonsurgical cases was compared each other between those with and without anticoagulant therapy.
    The recurrence ratio (the incidence of repeated
    TIA
    and/or newly developed completed stroke) in the present cooperative study can be summarized as follows;
    (1) the recurrence ratio was higher in
    TIA
    patients having any angiographically demonstrable cerebral arterial lesion, especially in the internal carotid artery, than in those without.
    (2) no difference of the recurrence ratios was observed between the degree of occlusive lesion.
    (3) the recurrence ratio in the anticoagulated cases was lower than that in non-anticoagulated cases.
    (4) the recurrence ratio in the surgical cases was lower than that of the nonsurgical cases.
    The study group on
    TIA
    criteria and detection. Heyman, A. et al.: IX. Transient focal cerebral ische-mia: Epidemiological and clinical aspects. Stroke, 5: 277, 1974.
  • 木村 和美
    脳卒中
    2010年 32 巻 6 号 719-724
    発行日: 2010/11/26
    公開日: 2010/12/03
    ジャーナル フリー
  • 尾原 知行, 山本 康正, 永金 義成, 田中 瑛次郎, 森井 芙貴子, 小泉 崇
    臨床神経学
    2011年 51 巻 6 号 406-411
    発行日: 2011年
    公開日: 2011/06/24
    ジャーナル フリー
    TIA
    連続105例をTOAST分類に準じて分類した.ラクナ
    TIA
    の定義は,塞栓源性心疾患や主幹動脈狭窄をみとめない例で,画像上穿通枝梗塞をみとめた例または症候として皮質症状がなく,一側の顔面・上肢・下肢のうち2カ所以上の運動あるいは感覚障害を呈した例とした.分類の結果ラクナ
    TIA
    は31%ともっとも多く,心原性
    TIA
    27%,アテローム血栓性
    TIA
    19%と続いた.ラクナ
    TIA
    は入院時血圧が高値で,
    TIA
    をくりかえす特徴があった.105例中6例で入院中に脳梗塞を発症し,3例がラクナ
    TIA
    の例であった.ラクナ
    TIA
    は本邦では少なくない病態で,脳梗塞へ進展する例も存在することから,その早期診断は重要と考えられた.
  • 峰松 一夫
    臨床神経学
    2010年 50 巻 11 号 907-908
    発行日: 2010年
    公開日: 2011/03/28
    ジャーナル フリー
    The diagnostic criteria and management strategy of transient ischemic attack (
    TIA
    ) have drastically changed for these years. In Europe and the United States, community and hospital-based studies demonstrated a higher risk of stroke immediately after a
    TIA
    than previously considered. Urgent evaluation and immediate initiation of treatment reduces stroke after a
    TIA
    dramatically. We establish the Japan
    TIA
    research group, which is subsidized by the Ministry of Health, Labour, and Welfare, Japan. The group conducted a nation-wide survey using a questionnaire and a retrospective registration study to clarify the current status of clinical practice of
    TIA
    in our country. We are also preparing a prospective, nation-wide, multicenter registration study of
    TIA
    patients. These topics were reviewed in this symposium.
  • 卜部 貴夫
    臨床神経学
    2010年 50 巻 11 号 910-912
    発行日: 2010年
    公開日: 2011/03/28
    ジャーナル フリー
    In the past, transient ischemic attack (
    TIA
    ) was defined as any sudden, focal cerebral ischemic event with neurological deficit lasting <24 hours. However, in several series of patients with
    TIA
    who underwent diffusion-weighted magnetic resonance imaging, many ischemic episodes with symptoms lasting <24 hours are associated with new infarctions. Therefore,
    TIA
    working group proposed a new tissue-based, rather than a time-based, definition of
    TIA
    : "a brief episode of neurological dysfunction caused by a focal disturbance of brain or retinal ischemia, with clinical symptoms typically lasting less than 1 hour, and without evidence of infarction". The latest definition of
    TIA
    is "a transient episode of neurological dysfunction caused by focal brain, spinal cord, or retinal ischemia, without acute infarction".
    Recent studies have shown that stroke risk after
    TIA
    is high in the first few days. Two prognostic scores for short-term risk of stroke after
    TIA
    have been proposed: the California score and the ABCD score. The ABCD2 score has the same components as ABCD, but with diabetes mellitus added. This score was a more accurate predictor than either of the previous scores.
    Antiplatelet therapy should be prescribed immediately for the secondary prevention of stroke in patients with a noncardioembolic
    TIA
    .
  • 内山 真一郎
    臨床神経学
    2010年 50 巻 11 号 904-906
    発行日: 2010年
    公開日: 2011/03/28
    ジャーナル フリー
    A new definition of transient ischemic attack (
    TIA
    ) was proposed by the working group of the American Heart Association and the American Stroke Association in 2009. In this definition,
    TIA
    is defined as a transient episode of neurological dysfunction caused by focal brain, spinal cord, or retinal ischemia, without acute infarction. This definition is currently much argued, and has not yet been globally accepted. There would be no meaning to differentiate
    TIA
    from ischemic stroke only by the duration of symptoms. Because,
    TIA
    in acute setting and acute ischemic stroke share the same spectrum. Therefore, we proposed a new clinical concept termed acute cerebrovascular syndrome (ACVS), which includes acute
    TIA
    and acute ischemic stroke. Patients early after
    TIA
    are at high risk of stroke and thus should be immediately evaluated and treated as a medical emergency, that is, ACVS. An international multicenter cooperative registry study is ongoing in 5,000 patients with
    TIA
    or minor stroke within 7 days after the onset, who will be followed up for 5 years, involving Japanese patients.
  • Shunta Mizuno, Fumiya Naito, Makoto Nakamura
    IEICE Electronics Express
    2017年 14 巻 10 号 20170310
    発行日: 2017年
    公開日: 2017/05/25
    [早期公開] 公開日: 2017/05/08
    ジャーナル フリー

    We present a novel bandwidth enhancement technique for a transimpedance amplifier (

    TIA
    ). The proposed
    TIA
    utilizes a common source topology and adopts the current mirror configuration using flipped voltage follower to increase the open-loop gain for the enhanced bandwidth with positive feedback. Circuit simulation results show that the proposed
    TIA
    makes it possible to increase the open-loop gain and enlarge the bandwidth by 40% compared with the conventional
    TIA
    .

  • TIA, RIND
    亀山 茂樹, 谷村 憲一, 小田 博重, 本田 吉穂
    Neurologia medico-chirurgica
    1985年 25 巻 5 号 340-347
    発行日: 1985/05/15
    公開日: 2006/09/21
    ジャーナル フリー
    Regional cerebral blood flow (rCBF) was measured in 25 patients with transient ischemic attacks (
    TIA
    ) and 34 patients with reversible ischemic neurological deficits (RIND) or ischemic strokes with full recovery. The rCBF measurements were performed by means of the 133Xe intracarotid injection method, using a scintillation camera and an on-line computer system. The rCBF data were analysed and compared with the computed tomography (CT) and angiographic findings on each patient.
    There was no significant difference in the average of the mean hemispheric values of rCBF (mean CBF) between
    TIA
    and RIND. The averages of mean CBF of
    TIA
    or RIND were significantly lower than those of the normal controls, and higher than those of the completed strokes. There was no correlation between the elapsed time from the last attack and the mean CBF in
    TIA
    . There was also no correlation between the elapsed time from the onset, or between the presence or absence of hemiparesis and the mean CBF in RIND. CT showed lacunae in 24% of
    TIA
    and 32% of RIND, whereas a cortical low density area was shown in only one case in each group. Angiographic abnormalities were found predominantly in the intracranial major arteries, rather than the extracranial carotid artery in both groups. Six patients of
    TIA
    (24%) and 6 of RIND (18%) had involvement of their extracranial internal carotid artery. There was no correlation between the mean CBF and angiographic findings. Although the mean CBF did not correlate to CT findings in
    TIA
    , it was significantly lower in RIND patients with lacunae on CT scans. Hemispheric pattern of flow distribution (HPFD) was disturbed in 88% of
    TIA
    and 74% of RIND. Focal ischemia was shown in only one case with RIND, whereas diffuse ischemia was shown in 2 cases with
    TIA
    and 5 cases with RIND. Loss of the hyperfrontal pattern which was thought to represent a mild diffuse cerebral dysfunction, was shown in 44% of
    TIA
    and 29% of RIND.
    Because diffuse involvement of HPFD was shown without reference for the elapsed time from the last attack of
    TIA
    or the onset of RIND, the authors support the ‘hemodynamic’ theory as opposed to ‘microembolic’ theory as the cause of
    TIA
    or RIND. It is concluded that
    TIA
    and RIND have the same causative factors, and the clinical difference of
    TIA
    and RIND is the only difference in recovery times between
    TIA
    and RIND.
  • 木村 和美
    脳卒中
    2015年 37 巻 3 号 194-196
    発行日: 2015年
    公開日: 2015/05/25
    ジャーナル フリー
    要旨:一過性脳虚血発作(
    TIA
    )は,
    TIA
    発作直後の脳梗塞発症の強力な予知因子である.ゆえに,
    TIA
    発作の直後から治療を開始しないといけない.一般市民は
    TIA
    の知識が不十分であり,市民啓発が重要である.
    TIA
    発作を診たときは,すみやかにアスピリンの投与を行い,その後,発症機序を推定し,その発症機序に合った治療を開始する.非心原性
    TIA
    には,抗血小板薬が投与されるが,
    TIA
    直後は2 剤併用投与がよいかもしれない.しかし,
    TIA
    発作3 ~ 4 週以降は,2 剤投与が脳梗塞の発症を予防できるとのエビデンスはない.心原性
    TIA
    では抗凝固薬が投与される.最近,新規経口抗凝固薬が登場した.心原性
    TIA
    発作直後より抗凝固薬の投与が望まれるが,新規経口抗凝固薬が,投与直後から抗凝固作用の効果が現れるので,新規経口抗凝固薬が,今後,主流になるかもしれない.高血圧,糖尿病,脂質異常症,喫煙,肥満などのリスクコントロールは必須である.
  • Toshiyuki Uehara, Tomoyuki Ohara, Kazuo Minematsu, Kazuyuki Nagatsuka, Kazunori Toyoda
    Internal Medicine
    2018年 57 巻 3 号 295-300
    発行日: 2018/02/01
    公開日: 2018/02/01
    [早期公開] 公開日: 2017/11/01
    ジャーナル オープンアクセス

    Objective The purpose of this study was to identify the predictors of subsequent ischemic stroke events in patients with transient ischemic attack (

    TIA
    ) attributable to intracranial arterial occlusive lesions.

    Methods The study population included 82 patients (55 men; mean age, 69.3±12.1 years) with

    TIA
    caused by intracranial arterial occlusive lesions who were admitted to our stroke care unit within 48 h of the onset of a
    TIA
    between April 2008 and November 2015.
    TIA
    was diagnosed if focal neurological symptoms ascribable to a vascular etiology lasted less than 24 h, irrespective of the presence of ischemic insults on imaging. The primary endpoint was an ischemic stroke event within 90 days of the onset of a
    TIA
    .

    Results The 90-day risk of ischemic stroke after the onset of a

    TIA
    was 14.6% [95% confidence interval (CI): 8.6-23.9%]. Cox proportional hazards multivariate analyses revealed that diffusion-weighted imaging (DWI) positivity [hazard ratio (HR), 8.73; 95%CI, 2.20-41.59; p=0.002], prior ischemic stroke (HR, 4.03; 95%CI, 1.07-15.99; p=0.040), and a high serum level of alkaline phosphatase (ALP) on admission (HR, 1.15; 95%CI, 1.05-1.26; p=0.002, for every +10 U/L) were significant independent predictors of ischemic stroke within 90 days after the onset of a
    TIA
    .

    Conclusion Our results suggested that patients with a

    TIA
    attributable to intracranial artery disease who showed DWI lesions, prior ischemic stroke, or high serum levels of ALP on admission were at high risk of subsequent ischemic stroke events.

  • 塩川 宰, 平橋 高明, 石束 隆男
    脳卒中
    1996年 18 巻 2 号 104-109
    発行日: 1996/04/25
    公開日: 2009/09/16
    ジャーナル フリー
    クレセンド (以下, クレ)
    TIA
    の臨床像の特徴を
    TIA
    発症機序との関係に於いて検討した.脳血管写をうけた
    TIA
    48例を, 最も推定される発症機序別に穿通枝病変群 (穿通群, 17例, 35%), 微小塞栓群 (微塞群, 15例, 31%), 脳血管不全群 (5例, 10%), 心原性塞栓群 (5例, 10%), および不明群 (6例, 13%) に分類した.クレ例は48例中7例 (14%) であり, 内訳は穿通群6例, 微塞群1例と穿通群に集中していた.穿通群のクレ例と非クレ例の臨床像には差はないが, 脳梗塞発症率 (%/人月) は非クレ例の0.6に対し, クレ例は1.6とクレ例での発症が多かった.また, クレ例からの脳梗塞発症は, すべて初回
    TIA
    発作後3日以内のことであった.一方, 微塞群のクレ例での脳梗塞発症はなかった.今回, 本邦でのクレ
    TIA
    は稀であり, その発症は高血圧を基礎とする穿通枝病変 (lipohyalinosisなど) を機序とする例に多く, 穿通群のクレ例では早期に脳梗塞に移行し易いことが示唆された.
  • 星野 晴彦
    脳卒中
    2010年 32 巻 6 号 725-730
    発行日: 2010/11/26
    公開日: 2010/12/03
    ジャーナル フリー
    【目的】
    TIA
    の抗血栓治療について検討した.【方法】2005年から5年間に入院となった
    TIA
    71例.【結果】
    TIA
    の病態はアテローム血栓性が20例(28.2%),心原性が12例(16.9%),その他が39例(54.9%)であった.入院中の抗血栓療法としては,アテローム血栓性
    TIA
    の27.3%は点滴による抗凝固と抗血小板の併用療法,45.0%が点滴による抗血小板療法が行われており,その他の
    TIA
    でも16.7%は点滴による併用療法,31.0%では点滴による抗血小板療法が行われていた.心原性
    TIA
    では58.3%が点滴による抗凝固療法であった.退院時にはアテローム血栓性
    TIA
    の30.0%では2剤抗血小板薬が投与されていた.【結論】ガイドラインには推奨がないが,
    TIA
    の急性期抗血栓療法は脳梗塞と基本的には同様に点滴による治療が主体であり,入院治療を行うことが迅速な治療開始に結びつくと考えられた.
  • 高本 剛
    脳卒中の外科
    2010年 38 巻 4 号 271-273
    発行日: 2010年
    公開日: 2011/04/29
    ジャーナル フリー
    Limb shaking is a rare symptom of transient ischemic attack (
    TIA
    ), and it is sometimes misdiagnosed as partial seizure. The pathological mechanism of the limb shaking remains unknown. I present a case of a 58-year-old man with crescent limb shaking
    TIA
    , caused by the severe right internal carotid artery stenosis. After the emergent carotid endarterectomy (CEA) was performed, the limb shaking
    TIA
    disappeared. Limb shaking
    TIA
    should be treated like a standard
    TIA
    .
  • Md. Yahia Zaman, Sheikh Shamimul Alam
    CYTOLOGIA
    2009年 74 巻 4 号 473-478
    発行日: 2009/12/30
    公開日: 2010/05/30
    ジャーナル オープンアクセス
    Two F1 hybrids namely
    TIA
    and PARROT and an open pollinated cultivar viz. TAJ-88 of Momordica charantia L. (bitter gourd) were cytogenetically investigated. The 3 cultivars were found to possess 2n=22 metacentric chromosomes. However, a plant specimen of cultivar
    TIA
    had 2n=44 chromosomes. The extreme symmetric karyotypes revealed these cultivars as primitive. Three CMA positive bands were found in
    TIA
    and PARROT whereas 4 were found in TAJ-88. On the other hand, a plant specimen of
    TIA
    had 6 CMA positive bands. The distribution, location and intensity of CMA positive bands were different among the 3 cultivars. A number of DAPI positive bands were found in
    TIA
    and PARROT. It was possible to identify some marker chromosomes with CMA and DAPI staining specific to each cultivar. Fluorescent banding indicated the occurrence of minute deletion and paracentric inversion in the genomes of these cultivars. The overall karyotypic features revealed that a plant specimen of cultivar
    TIA
    was actually an auto-tetraploid. With the help of fluorescent banding, the karyotype diversity among these 3 cultivars was determined.
  • 佐久間 克也, 大谷 秀昭, 加納 満和, 山本 勝美
    衛生化学
    1993年 39 巻 3 号 226-229
    発行日: 1993/06/30
    公開日: 2008/05/30
    ジャーナル フリー
    Tyrosinase inhibitory action (
    TIA
    ) of cosmetic raw materials containing cosmetic whitening ingredients was measured as an in vitro screening procedure. Among them, L-ascorbic acid phosphate magnesium salt (VC-PMg) had no
    TIA
    . The decomposition of VC-PMg was also examined by acid-phosphatase (Acp), a skin enzyme. Consequently, VC-PMg was hydrolyzed to L-ascorbic acid by pseudo first order reaction. The reaction solution containing L-ascorbic acid had
    TIA
    . The whitening effects of several cosmetic raw materials could be compared by the in vitro
    TIA
    test.
  • 伊藤 寿浩, 前田 龍太郎, 浅野 由香
    精密工学会誌
    2010年 76 巻 5 号 502-505
    発行日: 2010/05/05
    公開日: 2010/11/05
    ジャーナル フリー
  • Yoshiaki KONO, Yukiaki MANABE, Yasuo SATO
    Applied Entomology and Zoology
    1986年 21 巻 3 号 363-369
    発行日: 1986/08/25
    公開日: 2008/02/07
    ジャーナル フリー
    Insecticidal activities of three AChE inhibiting insecticides,
    TIA
    -230, fenitrothion and carbaryl, were compared in Spodoptera litura larvae. Inhibitory activities of the insecticides to AChE of isolated nerve cords and to AliE of fat body and haemolymph were also investigated. By injection,
    TIA
    -230 was the most insecticidal with an LD501/7.5 that of carbaryl. Fenitrothion was the least active, but its activated form, fenitroxon, showed tha same level of activity as
    TIA
    -230. There was no correlatino between insecticidal activiy and AChE inhibition. Fenitroxon showed very high affinity to AliE, so sequestering of this compound by AliE seemed to be one of the degradation factors. In
    TIA
    -230, the sequestering was not a degradation factor because of its low affinity to AliE. These results explained well why
    TIA
    -230 showed potent activity and fenitrothion did not. As to carbaryl, although oxidation and sequestering were ruled out as main degradation factors, the main factor could not be identified in these studies.
  • 澤田 徹, 水上 公宏
    Neurologia medico-chirurgica
    1978年 18pt2 巻 2 号 125-133
    発行日: 1978年
    公開日: 2006/12/28
    ジャーナル フリー
    Pathogenesis and etiologic factors in transient ischemic attack (
    TIA
    ) were briefly reviewed with emphasis on intra and extracranial atherosclerotic changes and indication for surgery.
    TIA
    is a clinical syndrome, which can only be defined by clinical features and is not confined to specific pathological changes in the brain or in the vascular system. Various pathogenic concepts and etiologic factors have been reported in the literature. The vasospasm theory in pathogenesis of
    TIA
    is now almost abandoned. There have been no experimental findings nor any other grounds to assume that vasospasm frequently causes
    TIA
    . Most patients with
    TIA
    become symptom-free by anticoagulation and many other evidences suggest that vast majorities of
    TIA
    are due to thromboembolism including so-called “microembolism.” However, transient fluctuations of cerebral perfusion pressure can also be a causative factor of
    TIA
    in a small number of cases, as pointed out by DennyBrown (so-called “cerebrovascular insufficiency”). In either case, the main etiologic factor can be attributed to atherosclerotic changes in the intra and extracranial arteries. Incidences of vascular changes in the intracranial cerebral arteries seem to be higher in this country than in European countries or in the USA.
    In rare cases of
    TIA
    , various other pathogenic conditions, such as polycythemia, thrombocytosis, kinkings and coilings of the cervical arteries, subclavian steal syndrome, moyamoya disease, etc, have been reported or experienced.
    Thromboendarterectomy of the cervical arteries and superficial temporal artery-to-middle cerebral artery (STA-MCA) anastomosis have been tried for surgical management of
    TIA
    . From a pathogenic point of view, thromboendartectomy is recommended for cases of
    TIA
    , which is caused by thromboembolism originated from atherosclerotic foci in the cervical arteries, while STA-MCA anastomosis might possibly be applied to cases of cerebrovascular insufficiency due to various vascular changes such as stenosis of the middle cerebral artery, internal carotid occlusion, and moyamoya disease.
  • Jiatian Li, Tesfaldet Habtemariam Hidru, Xiaolei Yang, Yiheng Yang, Fei Liu, Zengguo Lou, Xumin Guan, Shouling Wu, Yunlong Xia
    International Heart Journal
    2021年 62 巻 2 号 312-319
    発行日: 2021/03/30
    公開日: 2021/03/30
    [早期公開] 公開日: 2021/03/06
    ジャーナル フリー

    This study aims to evaluate the incidence of ischemic stroke or transient ischemic attack (

    TIA
    ) based on CHA2DS2-VASc scores in non-AF Chinese patients with sinus rhythm.

    We used health check-up data of 101,510 participants from the Kailuan Cohort Study. Participants' risk levels were defined by their CHA2DS2-VASc scores (range 0-3): Men with scores of 0, 1, or ≥ 2 and women with scores of 1, 2, or ≥ 3 were considered at low, intermediate, or high risk, respectively. Cox proportional hazards model was used to assess the association between the CHA2DS2-VASc-determined risk and the incidence of ischemic stroke/

    TIA
    .

    The mean 7.5 year follow-up examination revealed 2968 ischemic strokes/

    TIA
    events. The incidence rates for ischemic stroke/
    TIA
    events in men and women were 3.8% and 1.5%, respectively. The incidence of ischemic stroke/
    TIA
    increased with elevated predicted risks based on CHA2DS2-VASc scores in men: 2.2% for low-risk, 4.1% for intermediate-risk, and 7.8% for high-risk groups (P < 0.001 for trend). The incidences of ischemic stroke/
    TIA
    also increased with elevated predicted risks in women: 0.8% for low-risk, 2.1% for intermediate-risk, and 5.0% for high-risk groups (P < 0.001 for trend). Compared with low-risk group, the crude hazard ratio (95% confidence interval) of ischemic stroke/
    TIA
    for men in moderate- and high-risk groups were 1.96 (1.79-2.14; P < 0.001) and 4.18 (3.81-4.57; P < 0.001). Similar findings were observed in women.

    Risks of ischemic stroke/

    TIA
    events was high, particularly among those with high CHA2DS2-VASc scores.

  • Kodai Kanemaru, Takeshi Yoshimoto, Hiroshi Inoue, Takeshi Yamashita, Masaharu Akao, Hirotsugu Atarashi, Takanori Ikeda, Ken Okumura, Yukihiro Koretsune, Wataru Shimizu, Hiroyuki Tsutsui, Atsushi Hirayama, Masahiro Yasaka, Takenori Yamaguchi, Satoshi Teramukai, Tetsuya Kimura, Jumpei Kaburagi, Atsushi Takita, Kengo Kusano, Kazunori Toyoda, for the All Nippon Atrial Fibrillation in the Elderly (ANAFIE) Group
    Circulation Journal
    2020年 84 巻 3 号 516-523
    発行日: 2020/02/25
    公開日: 2020/02/25
    [早期公開] 公開日: 2020/01/25
    ジャーナル フリー HTML

    Background:Despite the well-established benefits in patients with non-valvular atrial fibrillation (NVAF), oral anticoagulants (OAC) have been underused in elderly patients. We investigated the characteristics and status of anti-thrombotic therapy in elderly NVAF patients in Japan according to a history of stroke or of transient ischemic attack (

    TIA
    ).

    Methods and Results:In a multicenter, prospective, observational study, 32,726 Japanese patients aged ≥75 years with NVAF were enrolled, and divided into 3 groups for the present analysis: 6,543 patients with previous ischemic stroke (IS) or

    TIA
    (2,410 women), 275 with previous hemorrhagic stroke (HS; 113 women), and the other 25,908 without previous stroke or
    TIA
    (11,470 women). Median CHADS2score was 5 in patients with IS/
    TIA
    , 2 in those with HS and 2 in those without stroke/
    TIA
    (P<0.05). Anti-thrombotic agents were used in 97.1% of patients with IS/
    TIA
    (OAC alone in 73.0%; antiplatelets alone in 3.7%; and both in 23.4%), 90.2% of those with HS (84.7%, 3.2%, and 12.1%, respectively), and 94.1% of those without stroke/
    TIA
    (83.4%, 2.7%, and 13.9%, respectively; P<0.05 for any anti-thrombotic choice). Of patients taking OAC, 72.2% received direct OAC (DOAC).

    Conclusions:In this unique nationwide NVAF registry of >30,000 elderly patients, >90% of patients, even those with HS, received anti-thrombotic therapy, nearly always with OAC. DOAC were the major choice of OAC.

feedback
Top