詳細検索結果
以下の条件での結果を表示する: 検索条件を変更
クエリ検索: %22%E3%83%90%E3%82%A4%E3%82%AA%E3%83%A1%E3%82%AB%E3%83%8B%E3%82%AF%E3%82%B9%22
5,121,519件中 1-20の結果を表示しています
  • 山口 昭彦
    日本中東学会年報
    1994年 9 巻 37-65
    発行日: 1994/03/31
    公開日: 2018/03/30
    ジャーナル フリー
    L'entree en Iran des armees britannique et sovietique s'est produite en aout 1941. Elle ebranla du coup le regime de la dynastie pahlavi qui etait au pouvoir depuis 16 ans, et mena le pays vers l'instabilite politique et le chaos social. La defaite de l'arme gouvernementale, qui etait le pivot du regime de Reza Shah, reduisit considerablement le controle du gouvernement central dans le pays. Cette situation politico-sociale confuse permit le developpement de differents mouvements politiques en Iran. C'est ainsi que le 16 aout 1942 le parti clandestin Komeley Jiyanewey Kurdistan (J-K) est ne a Mehabad, une ville au nord-ouest de l' Iran. Des sa formation, ce parti a su etendre sa sphere d'activite et, en une courte periode de temps, a fini par mettre sous son influence la ville et ses alentours. A la fin de la Seconde Guerre mondiale, en ete 1945, le J-K etait devenu une organisation representant le mouvement nationaliste kurde en Iran. C'est a ce moment-la qu'un autre parti politique, le Hizbi Dimokratiki Kurdistan (HDK), fonde par Qazi Mihemed a Mehabad aussi, devait remplacer le J-K. Des le
    22
    janvier 1946, le HDK proclama l'instauration de la≪Republique de Kurdistan≫. Cependant, les troupes sovietiques qui avaient pris sous leur protection la Republique evacuerent les terres iraniennes, en mai 1946. Six mois plus tard, sous la pression militaire du gouvernement central iranien, la republique s'ecroula. Deux theories tentent d'expliquer le passage du J-K au HDK. William Eagleton Jr., par exemple, affirme dans The Kurdish Republic of 1946 que le HDK a ete cree sur le conseil des autorites sovietiques. L'ex-secretaire general du Parti Democratique du Kurdistan d'Iran, 'Ebd el-Rehman Qasimlu maintient par contre que Qazi Mihemed a etabli le nouveau parti de sa propre initiative, eu regard a la situation politique de cette epoque-la. Il considere que la passage du J-K au HDK comme etant l'evolution d'un parti nationaliste clandestin en un parti democratique. En analysant ces deux theories et en se basant sur les autobiographies des personages qui se sont engages dans cet evenement, cette etude tentera d'examiner le principe directeur et les activites du J-K et de mieux comprendre les raisons pour lesquelles le J-K devait etre remplace par le HDK. La conclusion generale portera sur les differents objectifs politiques du J-K et du HDK. Le J-K visait l'elevation du niveau culturel du peuple tout en luttant contre le tribalisme, qui etait, selon lui, le probleme majeur de≪la nation kurde≫, et cela en ecartant toute idee de revolte militaire. Le J-K a aussi exclu de son cadre les elites sociales telles que les leaders des tribus et dirigeants religieux de peur qu'ils n'excercent une influence sur les membres du parti. L'automne de 1944 fut le debut d'une nouvelle ere pour le mouvement kurde. Alors que l'espoir de l'autodetermination augmentait parmi le peuple a mesure que s'approchait la fin de la guerre, la necessite de la force militaire a commence a se faire sentir dans le J-K. C'est pour cela que s'est produite au sein du parti une tendance a compter sur l'aide militaire des sovietiques et a recourir au leadership de Qazi Mihemed, qui avait une certaine influence meme sur les leaders tribaux. Mais cette tendance etait essentiellement incompatible avec la ligne fondamentale du J-K et, graduellement, a prive ce parti de sa raison d'etre. Ainsi, le HDK se substitua au J-K en tant que≪parti democratique≫visant a rallier d'abord les elites sociales sous sa banniere, en s'appuyant sur l'autorite personnelle de Qazi Mihemed.
  • 布施川 雄一, 多田 博己, 小熊 利明, 椎名 豊, 玉地 寛光, 半田 俊之介
    動脈硬化
    1996年 23 巻 9 号 545-551
    発行日: 1996/04/10
    公開日: 2011/09/21
    ジャーナル フリー
    The association between apolipoprotein
    E
    (Apo-
    E
    ) polymorphism and the response of plasma cholesterol to dietary therapy (cholesterol intake of less than 300mg/day) was investigated for about
    8
    weeks in 208 nonfamilial hypercholesterolemia patients (
    E
    3
    /
    3
    161,
    E
    4
    /
    3
    47). The baseline lipoprotein concentration and the intake of energy and lipids were not significantly different between subjects with
    E
    3
    /
    3
    and those with
    E
    4
    /
    3
    phenotypes. After the dietary therapy plasma total cholesterol and low density lipoprotein cholesterol were significantly decreased in both phenotype groups (p<0.05). The patients with
    E
    4
    /
    3
    had significantly smaller reductions of LDL-C than the patients with
    E
    3
    /
    3
    . The changes of LDL-C showed a significant difference between the patients with
    E
    3
    /
    3
    and
    E
    4
    /
    3
    by the Kruskal Wallis test (p=0.041). The presence of
    E
    4
    /
    3
    predicted the degree of cholesterol reduction following dietary therapy.
  • H. K. Mahanty
    CYTOLOGIA
    1970年 35 巻 1 号 13-49
    発行日: 1970/03/25
    公開日: 2009/03/19
    ジャーナル フリー
    1
    . The chromosome numbers of 64 species have been studied on which 56 are investigated for the first time.
    2. Morphological, anatomical and cytological findings on the Musaceae in the broad sense are considered from a phylogenetical standpoint and three distinct groups:
    a) Musa-Ensete,
    b
    ) Ravenala-Strelitzia-Phenakospermum and c) Holiconia are recognised as suggested by some authors. For these groups sub-familial status is proposed.
    3
    . Lowiaceae have been studied for the first time cytologically and their chromosome morphology, distinct from that of any other group of Zingiberales, confirms their claim to familial status.
    4
    . Consideration of the conflicting theories proposed to account for the higher chromosome number in genera like Globba, Alpinia, and Phaemeria, etc. leads to rejection of Chakravorti's hypothesis of wholesale fragmentation of chromosomes and the acceptance of the opposed view of Raghavan and Venkatasubban and others.
    5. Holttum's transference of the genus Zingiber to the tribe Hedychieae has been given cytological support on the following points:
    a) the basic number in the genus Zingiber correlates with that of Kaempferia.
    b
    ) the new tribe Alpinieae (which is infact Zingibereae without Zingiber) have consistently 48 chromosomes in their somatic complements.
    6. It is suggested that the African representatives of Kaempferia should be given the status of genus; Cienkowskya on the following points:
    a) the difference in floral morphology
    b
    ) geographical separateness and
    c) the difference in the number and morphology of the chromosomes. By comparing the present and past findings, various lines of evolution of the chromosome complements within each group are discussed.
    7. The basic number 11 is considered to be probably the original one for the Zingiberales as a whole, being present in Ravenala which is the most primitive member in the order. From this secondary basic numbers have arisen through evolution.
  • Tetsumi Tanabe, Katsuji Koyama, Masaharu Yasue, Hideaki Yokomizo, Kenji Sato, Jun Kokame, Norihiko Koori, Seiji Tanaka
    Journal of the Physical Society of Japan
    1976年 41 巻 2 号 361-367
    発行日: 1976/08/15
    公開日: 2007/06/01
    ジャーナル 認証あり
    The nucleus 12C was bombarded by
    82
    .
    1
    –MeV
    3He
    particles to study elastic and inelastic scattering and the (
    3He
    , α) reaction. Angular distributions were measured for the elastic scattering, for the inelastic scattering to levels at
    4
    .
    4
    , 7.6 and
    9
    .6 MeV in 12C, and for the (
    3He
    , α) reaction to levels at 0.0, 2.0,
    4
    .
    3
    (
    4
    .7) and 6.
    4
    MeV in 11C. The optical potential parameters were searched for to fit the
    3He
    elastic scattering angular distribution. The deformation parameters β2 and
    β3
    for 12C were determined from DWBA analysis. The angular distributions of α particles were compared with DWBA calculations and calculations including the two-step process via inelastic channel.
  • 川又 紀彦, 渡部 良平
    臨床血液
    2019年 60 巻 7 号 767-772
    発行日: 2019年
    公開日: 2019/08/06
    ジャーナル 認証あり

    BCR-ABL

    1
    International Scale(IS)測定はチロシンキナーゼ阻害剤で治療されている慢性骨髄性白血病(CML)患者の治療効果をモニターする上で重要な検査法である。稀ではあるが,BCR-ABL
    1
    IS測定ができないCMLが存在することが知られている。本研究において,我々は,そのようなBCR-ABL
    1
    IS測定のできないCML患者を経験し,分子生物学的な方法で,その原因を解明した。本例ではABL
    1
    遺伝子における切断点がa2エクソン内にあることが分かり,そのことがABL
    1
    のa2エクソンを欠いた
    e
    14a
    3
    b
    3
    a
    3
    )キメラ遺伝子のmRNAのみの発現を誘導していた。a2エクソンは本邦における検査部でのIS測定において重要な要素であり,これが欠損することが測定不能の原因であった。このようなIS測定ができない稀なCML症例をさらに集積して,その分子構造を解明することが待たれる。

  • Philippe Biane
    Publications of the Research Institute for Mathematical Sciences
    1995年 31 巻 1 号 63-79
    発行日: 1995年
    公開日: 2009/04/24
    ジャーナル フリー
  • Y. Nagai, T. Itahashi, S. Nakayama, N. Takahashi, H. Ejiri
    秋の分科会予稿集
    1976年 1976.1 巻
    発行日: 1976/09/16
    公開日: 2018/03/22
    会議録・要旨集 フリー
  • Daria Kurguzova, Svetlana Serebrova, Alexey Prokofiev, Ludmila Krasnykh, Galina Vasilenko, Marina Zhuravleva, Elena Smolyarchuk, Anton Barkov
    日本薬理学会年会要旨集
    2018年 WCP2018 巻 WCP2018_PO3-5-27
    発行日: 2018年
    公開日: 2020/09/10
    会議録・要旨集 オープンアクセス

    Background

    The differences in conditions of enteric-coated acid-labile drug release and absorption between healthy subjects in bioequivalence studies and gastrointestinal patients in clinical practice can lead to significant differences in gastric stability of original PPIs and generics. Thus, pathologic duodenogastric reflux (PDGR) and the pH increasing within PPIs administration still remain unaccounted for.

    Methods

    Two-stage modified comparative dissolution testing of original omeprazole (OO) and four generics (G

    1
    ;2;
    3
    ;
    4
    ) was performed. At first, we moved drugs from solution with pH
    1
    .2 (
    1
    .2±0.05) to pH 7.0 (7.0±0.05) and measure concentration of omeprazole in solution by high-performance liquid chromatography. According to our self-developed formula, pH 7 exposure time of resistance to PDGR for omeprazole is
    4
    minutes, i.
    e
    . the active substance should not be released within
    4
    minutes at pH 7. The exposure at the second stage was conducted with pH
    4
    (
    4
    .0±0.05), that imitated gastric pH after PPI administration. And then we also moved drugs to pH 7 with the subsequent measurement of omeprazole concentration.

    Results

    Omeprazole concentrations after

    4
    , 10, 15, 20, 30, 45, 60 minutes in pH 7 solution at the first stage were different for OO and generics. For OO, these values were
    4
    ,7±0,7%; 41,
    4
    ±
    3
    ,0%; 62,
    8
    ±
    4
    ,0%; 79,5±2,
    9
    %;
    83
    ,5±2,
    9
    %; 81,6±2,
    9
    %; 80,6±
    4
    ,
    4
    %; for Generic
    1
    - 0; 49,
    3
    ±
    9
    ,
    9
    %; 88,
    8
    ±2,
    8
    %;
    90
    ,
    4
    ±
    3
    ,7%; 88, 2±2,2%; 87,
    3
    ±2,0%; 85,
    9
    ±
    1
    ,
    1
    %; for Generic2 - 0; 30,6±6,
    3
    %; 66,7±
    8
    ,2%; 76,
    4
    ±7,
    4
    %;
    82
    ,
    8
    ±5,
    3
    %; 86,0±
    3
    ,7%; 84,6±
    3
    ,
    3
    %: for Generic
    3
    - 80,
    8
    ±
    3
    ,6%;
    83
    ,5±
    1
    ,
    9
    %;
    83
    ,
    8
    ±
    3
    ,2%;
    83
    ,
    3
    ±2,7%; 81,
    9
    ±2,
    1
    %;
    82
    ,
    1
    ±2,0%;
    82
    ,0±2,
    4
    %; for Generic
    4
    -
    82
    ,5±
    1
    ,7%; 84,
    4
    ±0,
    8
    %; 84,2±
    1
    ,2%;
    82
    ,
    9
    ±0,
    9
    %;
    82
    ,
    9
    ±0,
    9
    %;
    82
    ,
    9
    ±0,
    9
    %;
    82
    ,
    8
    ±
    1
    ,
    1
    %, respectively.

    An analysis of the omeprazole concentration in pH 7 solution at the second stage revealed the following parameters after the same time: for OO -

    4
    ,
    4
    ±0,6%; 40, 5±
    3
    ,0%; 62,
    8
    ±2,0%; 80,0±
    3
    ,
    1
    %; 85,
    4
    ±2,
    9
    %;
    82
    ,
    8
    ±
    3
    ,
    4
    %; 80,
    9
    ±
    3
    ,5%; for Generic
    1
    - 0; 67,0±7,
    8
    %; 89,7±2,
    3
    %; 91,
    9
    ±
    4
    ,
    3
    %; 89,
    1
    ±
    1
    ,6%; 88,
    3
    ±
    1
    ,
    4
    %; 87,
    8
    ±
    1
    ,2%; for Generic2 - 0; 42,2±5,6%; 75,
    1
    ±7,
    3
    %; 81,0±6,0%; 88,
    4
    ±
    3
    ,2%; 88, 6±
    1
    ,
    3
    %; 87,
    9
    ±
    1
    ,0%; for Generic
    4
    - 85,5±0,5%; 85,6±0,5%; 84,7±0,
    9
    %;
    82
    ,7±
    3
    ,0%; 84,
    4
    ±0,
    3
    %; 84,
    4
    ±0,
    3
    %; 84,
    3
    ±0,
    4
    %, respectively. Generic
    3
    release and degradation were completely realized at pH
    4
    .

    Conclusion

    Decreased gastric stability of Generic

    3
    and Generic
    4
    makes PDGR and inhibited gastric acid secretion due to PPIs administration the potential causes of decreased enteric-coated acid-labile drugs stability.

  • 馬場 輝郎
    照明学会雑誌
    1968年 52 巻 3 号 107-111
    発行日: 1968/03/25
    公開日: 2011/07/19
    ジャーナル フリー
  • E. camaldulensis, E. globulus における容積重, および材形質含量の樹幹内変異と標準値を示す位置について
    小名 俊博, 園田 哲也, 伊藤 一弥, 柴田 勝
    紙パ技協誌
    1995年 49 巻 8 号 1227-1234
    発行日: 1995/08/01
    公開日: 2009/11/16
    ジャーナル フリー
    Within-tree variations, whole-tree values and the representative heights for the whole tree value of basic density, and contents of wood components per volume were analysed for two trees of Eucalyptus camaldulensis and
    E
    . globulus
    respectively, grown at the seed orchard in Western Australia to do quality breeding.
    Within-tree variation of
    E
    . camaldulensis
    was rather uniform as 500±40, 532 ±34 kg/
    m3
    , but that of
    E
    . globulus
    was large as 595 ± 69, 616 ± 79 kg/
    m3
    and the basic density was higher in bark side and upper part in the trunk, to be expected to have higher pulp productivity.
    The whole-tree values of
    E
    . camaldulensis
    were 501, 520 kg/
    m3
    and those of
    E
    . globulus
    were 594, 640 kg/
    m3
    and the difference of the species was observed.
    Representative heights for the whole-tree contents ±5 % were 0.32.
    8
    m on
    E
    . camaldulensis
    , and 0.
    8
    and 2.
    8
    m on
    E
    . globulus
    regardless the differences in the whole-tree height and the within-tree variation when they were chosen below
    3
    .
    3
    m height for sampling an increment core.
    Representative heights were also determined for contents of wood components per volume as follows ; for
    E
    . camaldulensis
    , holocellulose :
    1
    .
    3
    , 2.
    8
    m, cellulose : 2.
    83
    .
    3
    m, hemicellulose : 0.
    82
    .
    8
    m, lignin : 0.81.
    3
    , 2.
    8
    m, extractives : 2.
    3
    m, alkali-extractives :
    1
    .
    3
    m, and total-extractives : 2.32.
    8
    m, for
    E
    . globulus
    , 2.
    8
    m, 2.32.
    8
    m, 2.
    8
    m, 0.30.
    8
    m, 2.
    83
    .
    3
    m, 2.
    83
    .
    3
    m and 2.
    8
    m in the same manner.
    It is expected that whole-tree pulp properties including pulp productivity are predicted by the increment core taken from these representative heights.
  • Nagai Y., Shibata T., Nakayama S., Ejiri H.
    秋の分科会予稿集
    1975年 1975.1 巻
    発行日: 1975/09/12
    公開日: 2018/03/22
    会議録・要旨集 フリー
  • 梶川 竜三
    日本機械学会誌
    1960年 63 巻 495 号 644-
    発行日: 1960/04/05
    公開日: 2017/06/21
    解説誌・一般情報誌 フリー
  • ―St. Jude Medical valveの抗血栓性について―
    藤田 康雄, 林 純一, 山崎 芳彦, 江口 昭治, 大谷 信一
    人工臓器
    1988年 17 巻 3 号 1133-1136
    発行日: 1988/06/15
    公開日: 2011/10/07
    ジャーナル フリー
    SJM弁の抗血栓性についてS-
    E
    ボール弁との比較検討を行った。S-
    E
    ボール弁で単弁置換をうけた132例と、SJM弁で単弁置換をうけた135例を対象とした。僧帽弁置換群の血栓塞栓症の発生頻度は、S-
    E
    非被覆弁2.14%/患者・年、S-
    E
    被覆弁
    1
    .
    82
    %/患者・年、SJM弁
    1
    .69%/患者・年であった。術後7年のThrombo-embolism Free RateはS-
    E
    非被覆弁で60.5±7.5%、S-
    E
    被覆弁で
    83
    .
    9
    ±5.2%、SJM弁で92.
    4
    ±
    3
    .
    1
    %であった。大動脈弁置換群の血栓塞栓症の発生頻度は、S-
    E
    非被覆弁
    1
    .36%/患者・年、S-
    E
    被覆弁、SJM弁では0であった。術後7年のThromboembolism Free RateはS-
    E
    非被覆弁75.6±10.6%、S-
    E
    被覆弁80.0±10.
    3
    %、SJM弁96.7±
    3
    .
    3
    %であった。SJM弁の抗血栓性はS-
    E
    非被覆弁に比し良好であったが、S-
    E
    被覆弁に比べ著しく向上したとはいえず、近年における血栓塞栓症の減少には厳重な抗凝固療法の施行も寄与していると考えられる。
  • Simon MAXWELL
    臨床薬理
    2008年 39 巻 5 号 141S-144S
    発行日: 2008年
    公開日: 2009/02/05
    ジャーナル フリー
  • 浅岡 顕, 大塚 悟, 松尾 稔
    土質工学会論文報告集
    1990年 30 巻 3 号 109-123
    発行日: 1990/09/15
    公開日: 2008/02/29
    ジャーナル フリー
    Limiting equilibrium state of saturated soils is solved taking into account drainage conditions during loading stage before reaching limit state. In analysis procedure, non-dilatant characteristics are assumed at limit state and then the failure problem discussed in the present study is concerned with normally consolidated and/or lightly overconsolidated soils. When solving statically indeterminate limiting equilibrium state one needs constitutive relations at limit state. In saturated soils, however, since the constitutive relations are generally expressed in terms of effective stresses, an additional field equation is required in order to link a velocity field to a pore pressure field. Therefore the problem should be solved as a coupling problem between these two fields. Two distinct types are discussed, one is undrained problem and the other, fully drained problem. Topics covered in the present study are as follows : (
    1
    ) Undrained bearing capacity and excavation stability of soft clays, (2) Bearing capacity under partly drained and/or partly swelling condition, (
    3
    ) Comparison between rapid loading condition and undrained condition, and (
    4
    ) Seepage failure of loose sandy soils under fully drained condition.
  • JURGEN GRABE, GERD GUDEHUS
    土質工学会論文報告集
    1992年 32 巻 3 号 130-136
    発行日: 1992/09/15
    公開日: 2008/02/29
    ジャーナル フリー
    The leaning tower of Pisa is a famous historical structure, especially in the field of soil mechanics. In this paper, the historical development of the inclination is reconstructed considering that a ground failure took place after each of the three construction phases. Model tests (scale
    1
    : 130) were carried out in order to predict that the tower will fail definitely, i.
    e
    . without any further disturbances, at an angle of inclination of 5.7°, which is dramatically close to the actual value of 5.5°. The estimated probability of failure rises very quickly with an increase in the angle of inclination. Conservation of the tower should be done therefore with utmost caution.
  • ASHRAF GHALY, ADEL HANNA, MIKHAIL HANNA
    土質工学会論文報告集
    1991年 31 巻 2 号 77-92
    発行日: 1991/06/15
    公開日: 2008/02/29
    ジャーナル フリー
    The performance of single pitch and multi pitch screw anchors during the application of installation torque is presented. An experimental testing program was conducted using five models of screw anchors with different geometry. The effect of the shape of the screw element, sand properties, and installation depth on the required installation torque value was examined. A theoretical model was developed from which the required installation torque value can be calculated in terms of the influencing factors. The required installation torque can be determined in terms of the ultimate uplift resistance calculated from any of the available theories. Based on the actual installation torque value measured in the field, the anticipated pullout capacity can be back calculated from the present theory. A comparison between theoretical and experimental results showed good agreement. Also, good agreement was observed when the present theoretical results were compared with the available field results reported in the literature.
  • Kazuo Isomae, Masago Ishikawa, Megumi Ohta, Yoichiro Ogawa, Hiroshi Hasegawa, Tadayuki Kohda, Junzo Kamei
    The Japanese Journal of Pharmacology
    2002年 88 巻 2 号 206-212
    発行日: 2002年
    公開日: 2002/03/20
    ジャーナル フリー
    The effects of T-
    82
    (2-[2-(
    1
    -benzylpiperidin-
    4
    -yl)ethyl]-2,
    3
    -dihydro-
    9
    -methoxy-
    1H
    -pyrrolo[
    3
    ,
    4
    -
    b
    ]quinolin-
    1
    -one hemifumarate), a new quinoline derivative, on acetylcholinesterase (AChE) activity and acetylcholine (ACh) release were compared with those of the well-known cholinesterase inhibitors tacrine and
    E
    2020. T-
    82
    , tacrine and
    E
    2020 all concentration-dependently inhibited AChE in rat brain homogenate (IC50s = 109.
    4
    , 84.2 and 11.
    8
    nM, respectively). In addition, although tacrine strongly inhibited butyrylcholinesterase (BuChE), T-
    82
    and
    E
    2020 showed only weak activity on BuChE in human plasma. In ex vivo experiments, intraperitoneal administration of T-
    82
    at a dose of 30 mg/kg inhibited AChE activity in the hippocampus, frontal cortex and parietal cortex of rats. The effect of T-
    82
    on the extracellular ACh concentration in rat brain was measured using in vivo microdialysis. T-
    82
    at doses of 10 and 30 mg/kg, i.p. increased the extracellular ACh concentration in the hippocampus and striatum in a dose-dependent manner. These findings suggest that T-
    82
    activates the central cholinergic system by selectively inhibiting AChE activity, while weakly affecting peripheral BuChE activity, and that T-
    82
    increases the extracellular ACh concentration in the brain, which is followed by inhibited AChE activity.
  • 膵臓
    2007年 22 巻 1 号 e399-e401
    発行日: 2007年
    公開日: 2007/03/27
    ジャーナル フリー
  • JACEK TEJCHMAN, IVO HERLE
    地盤工学会論文報告集
    1999年 39 巻 5 号 47-60
    発行日: 1999/10/15
    公開日: 2008/02/29
    ジャーナル フリー
    The bearing capacity of plane strain model footings on sand is numerically investigated with a finite element method and a polar hypoplastic constitutive law. The constitutive law is obtained through an extension of a non-polar hypoplastic constitutive law by polar quantities : rotations, curvatures, couple stresses and a characteristic length. It can reproduce the salient features of granular bodies while taking into account shear localisation. The hypoplastic constants are calibrated with element test calculations on the basis of plane strain and triaxial compression tests. The FE-analyses are performed for both different mean grain diameters and initial densities of dry medium sand, and footing widths. The effect of material constants on the load-displacement curve is also investigated. The FE-results are compared with model tests. Advantages and limitations of a polar hypoplastic approach are outlined.
feedback
Top