詳細検索結果
以下の条件での結果を表示する: 検索条件を変更
クエリ検索: %22%E3%83%91%E3%82%B7%E3%83%AA%22
4,967,444件中 1-20の結果を表示しています
  • Keishi Hata, Fuyuki Sugawara, Naganori Ohisa, Saori Takahashi, Kazuyuki Hori
    Biological and Pharmaceutical Bulletin
    2002年 25 巻 8 号 1040-1044
    発行日: 2002年
    公開日: 2002/08/01
    ジャーナル フリー
    We screened the differentiation-inducing activities of 39 mushroom extracts from Akita prefecture, Japan, on the mouse osteoblastic cell line, MC
    3
    T
    3
    -
    E
    1. Sixteen phosphate buffered saline (PBS), 8 boiled PBS, 14 ethanol and 12 methanol extracts induced alkaline phosphatase (ALP) activities, an indicator of MC
    3
    T
    3
    -
    E
    1 cell differentiation. The enzyme activities were markedly induced by extracts of Tricholoma auratum, and we isolated the active compound from methanol extracts of this mushroom. Physical data for the isolated active compound were identical to those for (
    22E
    ,24R)-ergosta-
    7
    ,
    22
    -diene-
    ,5α,6β-triol (1). 1 induced ALP activities of MC
    3
    T
    3
    -
    E
    1 cells and promoted cell proliferation. To investigate the relationships between the chemical structure and differentiation-inducing activity of the compound, ALP-inducing activities of MC
    3
    T
    3
    -
    E
    1 cells by 1, ergosterol (2), ergocalciferol (
    3
    ), cholesta-
    ,5α,6β-triol (4),
    7
    -dehydrocholesterol (5) and cholecalciferol (6) were tested. The enzyme activities of MC
    3
    T
    3
    -
    E
    1 cells were increased
    3
    .0-fold by 10 μM 1 and 2.4-fold by 10 μM 4. However, 2,
    3
    , 5 and 6 did not induce MC
    3
    T
    3
    -
    E
    1 cell ALP activity at 0.1—10 μM. These results suggested that the OH groups at C-5 and/or C-6 of 1 and 4 played an important role in their differentiation-inducing activities on MC
    3
    T
    3
    -
    E
    1 cells. Furthermore, 1 suppressed induction of MC
    3
    T
    3
    -
    E
    1 cell apoptosis by serum starvation.
  • Yosizo YAMAMOTO
    Nippon Sugaku-Buturigakkwai Kizi Dai
    3
    Ki

    1940年 22 巻 12 号 1048-1052
    発行日: 1940年
    公開日: 2009/06/09
    ジャーナル フリー
    The numerical values of the intervals betrween optieal levels are competed for the configurations
    1s22s22p83s23p83
    *94s, 5s, 6s and
    7
    s of Cu+, according to the general expression of energy-levels derived in the previous paper The self-consistent field radial functions computed by Hartree adn Hartree are used for1s, 2s, 2p,
    3
    s,
    3
    p and
    3
    d. Those of 4s, 5s,
    e
    .s and are ealenlated from Hartree Hartree's core-functions by the numerical integrations. The calculated results are shown in Table I.The agreement with experiment is satisfactory
  • Suguru TAKATSUTO, Kiyomi KOBAYASHI, Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE
    Agricultural and Biological Chemistry
    1988年 52 巻 12 号 3217-3218
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • 大澤 康次, 幡野 恵, 西宮 一尋, 岡崎 彬, 太田 真一, 宇田 文昭, 柳田 由紀, 檜垣 洋子, 吉田 知江里
    薬物動態
    1988年 3 巻 4 号 441-446
    発行日: 1988年
    公開日: 2007/03/29
    ジャーナル フリー
    ラットに
    3H
    -CU-
    83
    (S)を25μg/kgで静脈内あるいは経口投与し,血液中濃度および尿糞中排泄を検討した.
    静脈内投与後の血液中濃度推移は投与後5分より上昇し,投与後45分に25.74ng eq./mlのCmaxを示し,それ以後t1/2
    3
    .05時間とt1/2 33.09時間の二相で減少した.投与後72時間までのAUCは135.42ng eq.·hr/mlであった.
    経口投与では,投与後
    3
    時間でCmax 4.10ng eq./mlに達し,以後t1/2α 4.46時間とt1/2β 26.
    83
    時間の二相で減少した.投与後72時間までのAUCは48.62ng eq.·hr/mlであった.
    静脈内投与と経口投与のいずれの場合も,尿および糞中への放射能の排泄は,投与後48時間でほぼ終了した.静脈内投与では,投与後72時間までに投与量の30.52%が尿中に,60.42%が糞中に排泄された.経口投与では,同じく72時間までに40.34%が尿中に,69.24%が糞中に排泄された.
  • 山口 昭彦
    日本中東学会年報
    1994年 9 巻 37-65
    発行日: 1994/03/31
    公開日: 2018/03/30
    ジャーナル フリー
    L'entree en Iran des armees britannique et sovietique s'est produite en aout 1941. Elle ebranla du coup le regime de la dynastie pahlavi qui etait au pouvoir depuis 16 ans, et mena le pays vers l'instabilite politique et le chaos social. La defaite de l'arme gouvernementale, qui etait le pivot du regime de Reza Shah, reduisit considerablement le controle du gouvernement central dans le pays. Cette situation politico-sociale confuse permit le developpement de differents mouvements politiques en Iran. C'est ainsi que le 16 aout 1942 le parti clandestin Komeley Jiyanewey Kurdistan (J-K) est ne a Mehabad, une ville au nord-ouest de l' Iran. Des sa formation, ce parti a su etendre sa sphere d'activite et, en une courte periode de temps, a fini par mettre sous son influence la ville et ses alentours. A la fin de la Seconde Guerre mondiale, en ete 1945, le J-K etait devenu une organisation representant le mouvement nationaliste kurde en Iran. C'est a ce moment-la qu'un autre parti politique, le Hizbi Dimokratiki Kurdistan (HDK), fonde par Qazi Mihemed a Mehabad aussi, devait remplacer le J-K. Des le
    22
    janvier 1946, le HDK proclama l'instauration de la≪Republique de Kurdistan≫. Cependant, les troupes sovietiques qui avaient pris sous leur protection la Republique evacuerent les terres iraniennes, en mai 1946. Six mois plus tard, sous la pression militaire du gouvernement central iranien, la republique s'ecroula. Deux theories tentent d'expliquer le passage du J-K au HDK. William Eagleton Jr., par exemple, affirme dans The Kurdish Republic of 1946 que le HDK a ete cree sur le conseil des autorites sovietiques. L'ex-secretaire general du Parti Democratique du Kurdistan d'Iran, 'Ebd el-Rehman Qasimlu maintient par contre que Qazi Mihemed a etabli le nouveau parti de sa propre initiative, eu regard a la situation politique de cette epoque-la. Il considere que la passage du J-K au HDK comme etant l'evolution d'un parti nationaliste clandestin en un parti democratique. En analysant ces deux theories et en se basant sur les autobiographies des personages qui se sont engages dans cet evenement, cette etude tentera d'examiner le principe directeur et les activites du J-K et de mieux comprendre les raisons pour lesquelles le J-K devait etre remplace par le HDK. La conclusion generale portera sur les differents objectifs politiques du J-K et du HDK. Le J-K visait l'elevation du niveau culturel du peuple tout en luttant contre le tribalisme, qui etait, selon lui, le probleme majeur de≪la nation kurde≫, et cela en ecartant toute idee de revolte militaire. Le J-K a aussi exclu de son cadre les elites sociales telles que les leaders des tribus et dirigeants religieux de peur qu'ils n'excercent une influence sur les membres du parti. L'automne de 1944 fut le debut d'une nouvelle ere pour le mouvement kurde. Alors que l'espoir de l'autodetermination augmentait parmi le peuple a mesure que s'approchait la fin de la guerre, la necessite de la force militaire a commence a se faire sentir dans le J-K. C'est pour cela que s'est produite au sein du parti une tendance a compter sur l'aide militaire des sovietiques et a recourir au leadership de Qazi Mihemed, qui avait une certaine influence meme sur les leaders tribaux. Mais cette tendance etait essentiellement incompatible avec la ligne fondamentale du J-K et, graduellement, a prive ce parti de sa raison d'etre. Ainsi, le HDK se substitua au J-K en tant que≪parti democratique≫visant a rallier d'abord les elites sociales sous sa banniere, en s'appuyant sur l'autorite personnelle de Qazi Mihemed.
  • 浅岡 顕, 小高 猛司
    土質工学会論文報告集
    1992年 32 巻 3 号 117-129
    発行日: 1992/09/15
    公開日: 2008/02/29
    ジャーナル フリー
    Failure problems of saturated soils are classified in the present study into the following four types : Type I : The failure of loose and/or normally consolidated soils under fully drained loading conditions. Type II : The same soils but under perfectly undrained conditions. Type III : The failure of dense and/or overconsolidated soils under fully drained conditions. Type IV : The same soils but under perfectly undrained conditions. The soil-water coupling limiting equilibrium analysis on the basis of the critical state concept is shown possible to draw a distinction between type I, II and IV problems, and the limitations of the analysis procedure happen in solving the type problem in the above. This is demonstrated experimentally, in which seepage failure experiments in laboratory with the use of a saturated silty sand are employed to make distinctions clearly between the four types of failure problems. The definite distinctions both in failure load and failure mode appeared in the four types of experiments are summarized as follows : (1) the smallest failure load in loose sand in the undrained condition, (2) the largest failure load with the largest failure region in dense sand under undrained loading, (
    3
    ) the observation of no global deformation before failure within the soil under the fully drained condition that suggests the development of very localized shear deformation in the sand. Three out of four experiments are described well by the limit analysis computation mentioned above as far as the failure load and the shape and the size of the failure region after boiling failure are concerned, and thus the type III problem is identified to be the problem that should be solved by any other means in near future.
  • 斉 洋之, 高津戸 秀, 池川 信夫, 田中 洋子, スミス コニー, デルカ F.ヘクター
    Chemical and Pharmaceutical Bulletin
    1984年 32 巻 10 号 3866-3872
    発行日: 1984/10/25
    公開日: 2008/03/31
    ジャーナル フリー
    Chemical synthesis of (
    22
    E
    , 24R)- and (
    22
    E
    , 24S)-1, 24-dihydroxy-
    Δ22
    -vitamin
    D3
    has been achieved starting with the commercially available dinorcholenic acid acetate. Synthesis involved introduction of the 1-hydroxy group by a reduction of the 1, 2-epoxide generated by epoxidation of the 1, 4, 6-trien-
    3
    -one. The side chain on the steroid was then constructed by means of a Wittig reaction followed by introduction of the
    Δ7
    bond by standard methods and its protection with 1-phenyl-1, 2, 4-triazoline-
    3
    , 5-dione. Subsequent reduction of the hydroxy groups in the steroid side chain followed by reduction of the Diels-Alder addition products yielded the both 24-isomers. The 5,
    7
    -dienes were irradiated and the corresponding vitamin D compounds isolated. Nuclear magnetic resonance was used to identify individual isomers. The (
    22
    E
    , 24S)-1, 24-hydroxyvitamin
    D3
    compound bound equally well to the chick intestinal cytosol receptor as 1, 25-dihydroxyvitamin
    D3
    , while the 24R-isomer was approximately ten times less active. In vivo, both isomers were less active than 1, 25-dihydroxyvitamin
    D3
    ; however, the 24S-isomer was considerably more active than the 24R-isomer approaching the activity of 1, 25-dihydroxyvitamin
    D3
    .
  • 高木 徹, 林 賢治, 板橋 豊
    日本水産学会誌
    1984年 50 巻 8 号 1413-1418
    発行日: 1984/08/25
    公開日: 2008/02/29
    ジャーナル フリー
    The acetone extracts from three samples of the hepatopancreas of the poisonous scallops obtained on the Okhotsk Coast of Hokkaido Island were fractionated into two parts, hexane soluble fraction (fraction H) and 85% aqueous ethanol soluble fraction (fraction
    E
    ) by partition to two layers. The majortoxic components in the mouse assay of “diarrheic shellfish toxin” by intra-peritoneal injection were found to be free unsaturated fatty acids showed the following toxicity in MU per g, 18:1 n-9 35, 18:2 n-6
    83
    , 18:
    3
    n-
    3
    167, 18:4 n-
    3
    83
    , 20:5 n-
    3
    167, and
    22
    :6 n-
    3
    83
    , respectively. Toxicity of the fraction Hin MUper g was much lower than that of the fraction
    E
    . However, the toxicity of the fraction H per 1 g of the hepatopancreas was about twice that of the fraction
    E
    , since the fraction Hwas much more abundant than the fraction
    E
    in the hepatopancreas. The method for the assay of the diarrhetic shellfish toxin must be reexamined by considering the toxic effect of the free unsaturated fatty acids.
  • 馬場 輝郎
    照明学会雑誌
    1968年 52 巻 3 号 107-111
    発行日: 1968/03/25
    公開日: 2011/07/19
    ジャーナル フリー
  • 川又 紀彦, 渡部 良平
    臨床血液
    2019年 60 巻 7 号 767-772
    発行日: 2019年
    公開日: 2019/08/06
    ジャーナル 認証あり

    BCR-ABL1 International Scale(IS)測定はチロシンキナーゼ阻害剤で治療されている慢性骨髄性白血病(CML)患者の治療効果をモニターする上で重要な検査法である。稀ではあるが,BCR-ABL1 IS測定ができないCMLが存在することが知られている。本研究において,我々は,そのようなBCR-ABL1 IS測定のできないCML患者を経験し,分子生物学的な方法で,その原因を解明した。本例ではABL1遺伝子における切断点がa2エクソン内にあることが分かり,そのことがABL1のa2エクソンを欠いた

    e
    14a
    3
    b
    3
    a
    3
    )キメラ遺伝子のmRNAのみの発現を誘導していた。a2エクソンは本邦における検査部でのIS測定において重要な要素であり,これが欠損することが測定不能の原因であった。このようなIS測定ができない稀なCML症例をさらに集積して,その分子構造を解明することが待たれる。

  • Zhenhua Dan, Yasunobu Yamada, Yan Zhang, Masahiko Nishijima, Nobuyoshi Hara, Hiroyuki Matsumoto, Akihiro Makino
    MATERIALS TRANSACTIONS
    2013年 54 巻 4 号 561-565
    発行日: 2013/04/01
    公開日: 2013/03/25
    [早期公開] 公開日: 2013/02/22
    ジャーナル フリー
    The nanocrystalline soft-magnetic
    Fe83.3Si3B10P3Cu0.7
    ribbon alloy with a width of 10 mm prepared through annealing amorphous
    Fe83.3Si3B10P3Cu0.7
    ribbon alloy at 698 K had a saturation magnetization flux density of 1.
    82
    T and a coercivity of 11.8 A m−1. The nanohetero-amorphous microstructure consisted of α-Fe nanocrystals with an average size of
    22
    nm and amorphous neighbor phases. The results of polarization curves and electrochemical impedance spectra obtained in 0.5 M Na2SO4 and 0.5 M NaCl solutions demonstrated the positive shift of the corrosion potentials, the decrease in the passive current density, the increase in the breakdown potentials and the increase in the polarization resistance for the nanocrystalline
    Fe83.3Si3B10P3Cu0.7
    ribbon alloy, compared with its amorphous counterpart alloy. The corrosion performance was improved via annealing, which is thought to result from the enrichment of
    B2O3
    constituent in the surface oxide layer.
  • H. K. Mahanty
    CYTOLOGIA
    1970年 35 巻 1 号 13-49
    発行日: 1970/03/25
    公開日: 2009/03/19
    ジャーナル フリー
    1. The chromosome numbers of 64 species have been studied on which 56 are investigated for the first time.
    2. Morphological, anatomical and cytological findings on the Musaceae in the broad sense are considered from a phylogenetical standpoint and three distinct groups:
    a) Musa-Ensete,
    b
    ) Ravenala-Strelitzia-Phenakospermum and c) Holiconia are recognised as suggested by some authors. For these groups sub-familial status is proposed.
    3
    . Lowiaceae have been studied for the first time cytologically and their chromosome morphology, distinct from that of any other group of Zingiberales, confirms their claim to familial status.
    4. Consideration of the conflicting theories proposed to account for the higher chromosome number in genera like Globba, Alpinia, and Phaemeria, etc. leads to rejection of Chakravorti's hypothesis of wholesale fragmentation of chromosomes and the acceptance of the opposed view of Raghavan and Venkatasubban and others.
    5. Holttum's transference of the genus Zingiber to the tribe Hedychieae has been given cytological support on the following points:
    a) the basic number in the genus Zingiber correlates with that of Kaempferia.
    b
    ) the new tribe Alpinieae (which is infact Zingibereae without Zingiber) have consistently 48 chromosomes in their somatic complements.
    6. It is suggested that the African representatives of Kaempferia should be given the status of genus; Cienkowskya on the following points:
    a) the difference in floral morphology
    b
    ) geographical separateness and
    c) the difference in the number and morphology of the chromosomes. By comparing the present and past findings, various lines of evolution of the chromosome complements within each group are discussed.
    7
    . The basic number 11 is considered to be probably the original one for the Zingiberales as a whole, being present in Ravenala which is the most primitive member in the order. From this secondary basic numbers have arisen through evolution.
  • 斉 洋之, 高津戸 秀, 池川 信夫
    Chemical and Pharmaceutical Bulletin
    1985年 33 巻 11 号 4815-4820
    発行日: 1985/11/25
    公開日: 2008/03/31
    ジャーナル フリー
    Two new vitamin
    D3
    analogues, 1α-hydroxy-24, 24-dimethyl-
    22
    E
    -dehydrovitamin
    D3
    (13) and 1α, 25-dihydroxy-24, 24-dimethyl-
    22
    E
    -dehydrovitamin
    D3
    (17), which are blocked for 24-hydroxylation by the methyl groups, were synthesized from 1α,
    -bismethoxymethoxypregn-5-ene-20Scarbaldehyde (6) by using the orthoester Claisen rearrangement for construction of the carbon skeleton of their side chains. These compounds (13 and 17) elicited a rise in serum calcium, but not in serum inorganic phosphorus in rats. In a bioassay for alkaline phosphatase, they were found to show much weaker activity than 1α-hydroxy vitamin
    D3
    (5).
  • Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE, Kiyomi KOBAYASHI, Suguru TAKATSUTO
    Agricultural and Biological Chemistry
    1988年 52 巻 8 号 2117-2118
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • PIETRO DE RUGGIERI, Carmelo Gandolfi, Umberto Guzzi
    International Symposium on the Chemistry of Natural Products
    1964年 1964 巻 E-7-3
    発行日: 1964/04/12
    公開日: 2017/08/18
    会議録・要旨集 フリー
  • Philippe Biane
    Publications of the Research Institute for Mathematical Sciences
    1995年 31 巻 1 号 63-79
    発行日: 1995年
    公開日: 2009/04/24
    ジャーナル フリー
  • 膵臓
    2007年 22 巻 1 号 e350-e352
    発行日: 2007年
    公開日: 2007/03/27
    ジャーナル フリー
  • Wei Xu, Rui Xia, Feng Tian, Lei Liu, Meng Li, Shiyuan Fang
    Journal of Hard Tissue Biology
    2022年 31 巻 4 号 263-268
    発行日: 2022年
    公開日: 2022/10/27
    ジャーナル フリー

    Fracture healing is a complex dynamic process that involves the balance between osteoblasts and osteoclasts. Several microRNAs (miRNAs) have been shown to participate in fracture healing. In this study, we investigated the role of miR-324-

    3
    p in osteoblast differentiation. MC
    3
    T
    3
    -
    E
    1 cell differentiation was induced by icariin, and miR-324-
    3
    p expression levels during cell differentiation were measured using qRT-PCR. Cell proliferation and differentiation were assessed to evaluate the function of miR-324-
    3
    p. Luciferase activity was used for target gene verification. During MC
    3
    T
    3
    -
    E
    1 differentiation, miR-324-
    3
    p levels gradually increased over time. Further experiments showed that miR-324-
    3
    p overexpression significantly promoted cell viability, whereas miR-324-
    3
    p downregulation showed the opposite effect. For cells with miR-324-
    3
    p mimic, the levels of bone sialoprotein, Runx2, osteocalcin, and alkaline phosphatase activity were significantly elevated. SMAD
    7
    is the target gene of miR-324-
    3
    p, and its level is gradually downregulated during MC
    3
    T
    3
    -
    E
    1 cell differentiation. MiR-324-
    3
    p may promote MC
    3
    T
    3
    -
    E
    1 cell differentiation by targeting SMAD
    7
    .

  • Daria Kurguzova, Svetlana Serebrova, Alexey Prokofiev, Ludmila Krasnykh, Galina Vasilenko, Marina Zhuravleva, Elena Smolyarchuk, Anton Barkov
    日本薬理学会年会要旨集
    2018年 WCP2018 巻 WCP2018_PO3-5-27
    発行日: 2018年
    公開日: 2020/09/10
    会議録・要旨集 オープンアクセス

    Background

    The differences in conditions of enteric-coated acid-labile drug release and absorption between healthy subjects in bioequivalence studies and gastrointestinal patients in clinical practice can lead to significant differences in gastric stability of original PPIs and generics. Thus, pathologic duodenogastric reflux (PDGR) and the pH increasing within PPIs administration still remain unaccounted for.

    Methods

    Two-stage modified comparative dissolution testing of original omeprazole (OO) and four generics (G1;2;

    3
    ;4) was performed. At first, we moved drugs from solution with pH 1.2 (1.2±0.05) to pH
    7
    .0 (
    7
    .0±0.05) and measure concentration of omeprazole in solution by high-performance liquid chromatography. According to our self-developed formula, pH
    7
    exposure time of resistance to PDGR for omeprazole is 4 minutes, i.
    e
    . the active substance should not be released within 4 minutes at pH
    7
    . The exposure at the second stage was conducted with pH 4 (4.0±0.05), that imitated gastric pH after PPI administration. And then we also moved drugs to pH
    7
    with the subsequent measurement of omeprazole concentration.

    Results

    Omeprazole concentrations after 4, 10, 15, 20, 30, 45, 60 minutes in pH

    7
    solution at the first stage were different for OO and generics. For OO, these values were 4,
    7
    ±0,
    7
    %; 41,4±
    3
    ,0%; 62,8±4,0%; 79,5±2,9%;
    83
    ,5±2,9%; 81,6±2,9%; 80,6±4,4%; for Generic1 - 0; 49,
    3
    ±9,9%; 88,8 ±2,8%; 90,4±
    3
    ,
    7
    %; 88, 2±2,2%; 87,
    3
    ±2,0%; 85,9±1,1%; for Generic2 - 0; 30,6±6,
    3
    %; 66,
    7
    ±8,2%; 76,4±
    7
    ,4%;
    82
    ,8±5,
    3
    %; 86,0±
    3
    ,
    7
    %; 84,6±
    3
    ,
    3
    %: for Generic
    3
    - 80,8±
    3
    ,6%;
    83
    ,5±1,9%;
    83
    , 8±
    3
    ,2%;
    83
    ,
    3
    ±2,
    7
    %; 81,9±2,1%;
    82
    ,1±2,0%;
    82
    ,0±2,4%; for Generic4 -
    82
    ,5±1,
    7
    %; 84,4±0,8%; 84,2±1,2%;
    82
    , 9±0,9%;
    82
    ,9±0,9%;
    82
    ,9±0,9%;
    82
    ,8±1,1%, respectively.

    An analysis of the omeprazole concentration in pH

    7
    solution at the second stage revealed the following parameters after the same time: for OO - 4,4±0,6%; 40, 5±
    3
    ,0%; 62,8±2,0%; 80,0±
    3
    ,1%; 85,4±2,9%;
    82
    ,8±
    3
    ,4%; 80,9±
    3
    ,5%; for Generic1 - 0; 67,0±
    7
    ,8%; 89,
    7
    ±2,
    3
    %;
    91
    , 9±4,
    3
    %; 89,1±1,6%; 88,
    3
    ±1,4%; 87,8±1,2%; for Generic2 - 0; 42,2±5,6%; 75,1±
    7
    ,
    3
    %; 81,0±6,0%; 88,4±
    3
    ,2%; 88, 6±1,
    3
    %; 87,9±1,0%; for Generic4 - 85,5±0,5%; 85,6±0,5%; 84,
    7
    ±0,9%;
    82
    ,
    7
    ±
    3
    ,0%; 84,4±0,
    3
    %; 84,4±0,
    3
    %; 84,
    3
    ±0,4%, respectively. Generic
    3
    release and degradation were completely realized at pH 4.

    Conclusion

    Decreased gastric stability of Generic

    3
    and Generic4 makes PDGR and inhibited gastric acid secretion due to PPIs administration the potential causes of decreased enteric-coated acid-labile drugs stability.

  • E. camaldulensis, E. globulus における容積重, および材形質含量の樹幹内変異と標準値を示す位置について
    小名 俊博, 園田 哲也, 伊藤 一弥, 柴田 勝
    紙パ技協誌
    1995年 49 巻 8 号 1227-1234
    発行日: 1995/08/01
    公開日: 2009/11/16
    ジャーナル フリー
    Within-tree variations, whole-tree values and the representative heights for the whole tree value of basic density, and contents of wood components per volume were analysed for two trees of Eucalyptus camaldulensis and
    E
    . globulus
    respectively, grown at the seed orchard in Western Australia to do quality breeding.
    Within-tree variation of
    E
    . camaldulensis
    was rather uniform as 500±40, 532 ±34 kg/
    m3
    , but that of
    E
    . globulus
    was large as 595 ± 69, 616 ± 79 kg/
    m3
    and the basic density was higher in bark side and upper part in the trunk, to be expected to have higher pulp productivity.
    The whole-tree values of
    E
    . camaldulensis
    were 501, 520 kg/
    m3
    and those of
    E
    . globulus
    were 594, 640 kg/
    m3
    and the difference of the species was observed.
    Representative heights for the whole-tree contents ±5 % were 0.32.8 m on
    E
    . camaldulensis
    , and 0.8 and 2.8 m on
    E
    . globulus
    regardless the differences in the whole-tree height and the within-tree variation when they were chosen below
    3
    .
    3
    m height for sampling an increment core.
    Representative heights were also determined for contents of wood components per volume as follows ; for
    E
    . camaldulensis
    , holocellulose : 1.
    3
    , 2.8 m, cellulose : 2.
    83
    .
    3
    m, hemicellulose : 0.
    82
    . 8 m, lignin : 0.81.
    3
    , 2.8 m, extractives : 2.
    3
    m, alkali-extractives : 1.
    3
    m, and total-extractives : 2.32.8 m, for
    E
    . globulus
    , 2.8 m, 2.32.8 m, 2.8 m, 0.30.8 m, 2.
    83
    .
    3
    m, 2.
    83
    .
    3
    m and 2.8 m in the same manner.
    It is expected that whole-tree pulp properties including pulp productivity are predicted by the increment core taken from these representative heights.
feedback
Top