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  • L. STERU, R.D. PORSOLT
    臨床薬理
    1989年 20 巻 1 号 77-78
    発行日: 1989/03/31
    公開日: 2010/06/28
    ジャーナル フリー
  • ―特にアポ蛋白Eの変化について―
    本間 康彦, 三神 美和, 佐藤 美智子, 石原 仁一, 吉川 広, 木下 栄治, 田川 隆介, 星合 充基, 古屋 秀夫, 井出 満, 田辺 晃久, 玉地 寛光, 兼本 成斌, 友田 春夫, 中谷 矩章, 五島 雄一郎
    動脈硬化
    1984年 12 巻 3 号 599-603
    発行日: 1984/08/01
    公開日: 2011/09/21
    ジャーナル フリー
    Seven hundred fifty mg of cholesterol were fed daily to 32 patients of the ischemic heart disease (IHD) for 2 weeks. Cholesterol amounts in VLDL, LDL, HDL, HDL2 and
    HDL3
    were estimated on the 0th, 7th and 14th days of cholesterol load. Plasma apoprotein A-I, A-II,
    B
    , C-II,
    E
    levels were also measured in 16 from 32 IHD subjects. Apoprotein levels were estimated by a method of single radial immunodiffusion (SRID). Before cholesterol administration, cholesterol amounts in VLDL, LDL, HDL, HDL2 and
    HDL3
    were 15.9±7.5mg/dl (mean±SD), 150.9±58.1mg/dl 43.
    8
    ±9.6mg/dl, 16.4±5.
    8
    mg/dl and 24.9±6.
    3
    mg/dl respectively. Plasma apoprotein A-I, A-II,
    B
    , C-II and
    E
    levels were 81.7±
    22
    .0 mg/dl, 15.1±5.4mg/dl,
    93
    .7±36.0mg/dl,
    3
    .
    83
    ±1.00mg/dl and 4.29±1.36mg/dl respectively. After 2 weeks' cholesterol feeding, all plasma lipoprotein cholesterol and apoprotein levels did not change significantly. Correlation coefficients between plasma apoprotein and lipoprotein cholesterol levels were calculated. Apoprotein A-I and A-II correlated with HDL-C (r=0.348), HDL2-C (r=0.612) and
    HDL3
    (r=0.569). Apoprotein
    B
    correlated with total cholesterol (TC) (r=0.610), VLDL-C (r=0.341), LDL-C (r=0.726), HDL-C (r=0.432) and HDL2-C (r=0.465). Apoprotein C-II correlated with TC (r=0.765), TG (r=0.679), VLDL-C (r=0.651), LDL-C (r=0.461) and HDL2-C (r=0.326). Apoprotein
    E
    correlated with TC (r=0.580), TG (r=0.575) and VLDL-C (r=0.666). Interapoprotein's correlations were also calculated. Apoprotein A-I correlated with apoprotein A-II (r=0.468). Apoprotein
    B
    correlated with apoprotein C-II (r=0.393). Apoprotein C-II correlated with apoprotein
    B
    (r=0.393) and
    E
    (r=0.549). Apoprotein
    E
    only correlated with apoprotein C-II (r=0.549).
  • Keishi Hata, Fuyuki Sugawara, Naganori Ohisa, Saori Takahashi, Kazuyuki Hori
    Biological and Pharmaceutical Bulletin
    2002年 25 巻 8 号 1040-1044
    発行日: 2002年
    公開日: 2002/08/01
    ジャーナル フリー
    We screened the differentiation-inducing activities of 39 mushroom extracts from Akita prefecture, Japan, on the mouse osteoblastic cell line, MC
    3
    T
    3
    -
    E
    1. Sixteen phosphate buffered saline (PBS),
    8
    boiled PBS, 14 ethanol and 12 methanol extracts induced alkaline phosphatase (ALP) activities, an indicator of MC
    3
    T
    3
    -
    E
    1 cell differentiation. The enzyme activities were markedly induced by extracts of Tricholoma auratum, and we isolated the active compound from methanol extracts of this mushroom. Physical data for the isolated active compound were identical to those for (
    22E
    ,24R)-ergosta-7,
    22
    -diene-
    ,5α,6β-triol (1). 1 induced ALP activities of MC
    3
    T
    3
    -
    E
    1 cells and promoted cell proliferation. To investigate the relationships between the chemical structure and differentiation-inducing activity of the compound, ALP-inducing activities of MC
    3
    T
    3
    -
    E
    1 cells by 1, ergosterol (2), ergocalciferol (
    3
    ), cholesta-
    ,5α,6β-triol (4), 7-dehydrocholesterol (5) and cholecalciferol (6) were tested. The enzyme activities of MC
    3
    T
    3
    -
    E
    1 cells were increased
    3
    .0-fold by 10 μM 1 and 2.4-fold by 10 μM 4. However, 2,
    3
    , 5 and 6 did not induce MC
    3
    T
    3
    -
    E
    1 cell ALP activity at 0.1—10 μM. These results suggested that the OH groups at C-5 and/or C-6 of 1 and 4 played an important role in their differentiation-inducing activities on MC
    3
    T
    3
    -
    E
    1 cells. Furthermore, 1 suppressed induction of MC
    3
    T
    3
    -
    E
    1 cell apoptosis by serum starvation.
  • Suguru TAKATSUTO, Kiyomi KOBAYASHI, Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE
    Agricultural and Biological Chemistry
    1988年 52 巻 12 号 3217-3218
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • 大澤 康次, 幡野 恵, 西宮 一尋, 岡崎 彬, 太田 真一, 宇田 文昭, 柳田 由紀, 檜垣 洋子, 吉田 知江里
    薬物動態
    1988年 3 巻 4 号 441-446
    発行日: 1988年
    公開日: 2007/03/29
    ジャーナル フリー
    ラットに
    3H
    -CU-
    83
    (S)を25μg/kgで静脈内あるいは経口投与し,血液中濃度および尿糞中排泄を検討した.
    静脈内投与後の血液中濃度推移は投与後5分より上昇し,投与後45分に25.74ng eq./mlのCmaxを示し,それ以後t1/2
    3
    .05時間とt1/2 33.09時間の二相で減少した.投与後72時間までのAUCは135.42ng eq.·hr/mlであった.
    経口投与では,投与後
    3
    時間でCmax 4.10ng eq./mlに達し,以後t1/2α 4.46時間とt1/2β 26.
    83
    時間の二相で減少した.投与後72時間までのAUCは48.62ng eq.·hr/mlであった.
    静脈内投与と経口投与のいずれの場合も,尿および糞中への放射能の排泄は,投与後48時間でほぼ終了した.静脈内投与では,投与後72時間までに投与量の30.52%が尿中に,60.42%が糞中に排泄された.経口投与では,同じく72時間までに40.34%が尿中に,69.24%が糞中に排泄された.
  • 斉 洋之, 高津戸 秀, 池川 信夫, 田中 洋子, スミス コニー, デルカ F.ヘクター
    Chemical and Pharmaceutical Bulletin
    1984年 32 巻 10 号 3866-3872
    発行日: 1984/10/25
    公開日: 2008/03/31
    ジャーナル フリー
    Chemical synthesis of (
    22
    E
    , 24R)- and (
    22
    E
    , 24S)-1, 24-dihydroxy-
    Δ22
    -vitamin
    D3
    has been achieved starting with the commercially available dinorcholenic acid acetate. Synthesis involved introduction of the 1-hydroxy group by a reduction of the 1, 2-epoxide generated by epoxidation of the 1, 4, 6-trien-
    3
    -one. The side chain on the steroid was then constructed by means of a Wittig reaction followed by introduction of the Δ7 bond by standard methods and its protection with 1-phenyl-1, 2, 4-triazoline-
    3
    , 5-dione. Subsequent reduction of the hydroxy groups in the steroid side chain followed by reduction of the Diels-Alder addition products yielded the both 24-isomers. The 5, 7-dienes were irradiated and the corresponding vitamin D compounds isolated. Nuclear magnetic resonance was used to identify individual isomers. The (
    22
    E
    , 24S)-1, 24-hydroxyvitamin
    D3
    compound bound equally well to the chick intestinal cytosol receptor as 1, 25-dihydroxyvitamin
    D3
    , while the 24R-isomer was approximately ten times less active. In vivo, both isomers were less active than 1, 25-dihydroxyvitamin
    D3
    ; however, the 24S-isomer was considerably more active than the 24R-isomer approaching the activity of 1, 25-dihydroxyvitamin
    D3
    .
  • 山口 昭彦
    日本中東学会年報
    1994年 9 巻 37-65
    発行日: 1994/03/31
    公開日: 2018/03/30
    ジャーナル フリー
    L'entree en Iran des armees britannique et sovietique s'est produite en aout 1941. Elle ebranla du coup le regime de la dynastie pahlavi qui etait au pouvoir depuis 16 ans, et mena le pays vers l'instabilite politique et le chaos social. La defaite de l'arme gouvernementale, qui etait le pivot du regime de Reza Shah, reduisit considerablement le controle du gouvernement central dans le pays. Cette situation politico-sociale confuse permit le developpement de differents mouvements politiques en Iran. C'est ainsi que le 16 aout 1942 le parti clandestin Komeley Jiyanewey Kurdistan (J-K) est ne a Mehabad, une ville au nord-ouest de l' Iran. Des sa formation, ce parti a su etendre sa sphere d'activite et, en une courte periode de temps, a fini par mettre sous son influence la ville et ses alentours. A la fin de la Seconde Guerre mondiale, en ete 1945, le J-K etait devenu une organisation representant le mouvement nationaliste kurde en Iran. C'est a ce moment-la qu'un autre parti politique, le Hizbi Dimokratiki Kurdistan (HDK), fonde par Qazi Mihemed a Mehabad aussi, devait remplacer le J-K. Des le
    22
    janvier 1946, le HDK proclama l'instauration de la≪Republique de Kurdistan≫. Cependant, les troupes sovietiques qui avaient pris sous leur protection la Republique evacuerent les terres iraniennes, en mai 1946. Six mois plus tard, sous la pression militaire du gouvernement central iranien, la republique s'ecroula. Deux theories tentent d'expliquer le passage du J-K au HDK. William Eagleton Jr., par exemple, affirme dans The Kurdish Republic of 1946 que le HDK a ete cree sur le conseil des autorites sovietiques. L'ex-secretaire general du Parti Democratique du Kurdistan d'Iran, 'Ebd el-Rehman Qasimlu maintient par contre que Qazi Mihemed a etabli le nouveau parti de sa propre initiative, eu regard a la situation politique de cette epoque-la. Il considere que la passage du J-K au HDK comme etant l'evolution d'un parti nationaliste clandestin en un parti democratique. En analysant ces deux theories et en se basant sur les autobiographies des personages qui se sont engages dans cet evenement, cette etude tentera d'examiner le principe directeur et les activites du J-K et de mieux comprendre les raisons pour lesquelles le J-K devait etre remplace par le HDK. La conclusion generale portera sur les differents objectifs politiques du J-K et du HDK. Le J-K visait l'elevation du niveau culturel du peuple tout en luttant contre le tribalisme, qui etait, selon lui, le probleme majeur de≪la nation kurde≫, et cela en ecartant toute idee de revolte militaire. Le J-K a aussi exclu de son cadre les elites sociales telles que les leaders des tribus et dirigeants religieux de peur qu'ils n'excercent une influence sur les membres du parti. L'automne de 1944 fut le debut d'une nouvelle ere pour le mouvement kurde. Alors que l'espoir de l'autodetermination augmentait parmi le peuple a mesure que s'approchait la fin de la guerre, la necessite de la force militaire a commence a se faire sentir dans le J-K. C'est pour cela que s'est produite au sein du parti une tendance a compter sur l'aide militaire des sovietiques et a recourir au leadership de Qazi Mihemed, qui avait une certaine influence meme sur les leaders tribaux. Mais cette tendance etait essentiellement incompatible avec la ligne fondamentale du J-K et, graduellement, a prive ce parti de sa raison d'etre. Ainsi, le HDK se substitua au J-K en tant que≪parti democratique≫visant a rallier d'abord les elites sociales sous sa banniere, en s'appuyant sur l'autorite personnelle de Qazi Mihemed.
  • E. camaldulensis, E. globulus における容積重, および材形質含量の樹幹内変異と標準値を示す位置について
    小名 俊博, 園田 哲也, 伊藤 一弥, 柴田 勝
    紙パ技協誌
    1995年 49 巻 8 号 1227-1234
    発行日: 1995/08/01
    公開日: 2009/11/16
    ジャーナル フリー
    Within-tree variations, whole-tree values and the representative heights for the whole tree value of basic density, and contents of wood components per volume were analysed for two trees of Eucalyptus camaldulensis and
    E
    . globulus
    respectively, grown at the seed orchard in Western Australia to do quality breeding.
    Within-tree variation of
    E
    . camaldulensis
    was rather uniform as 500±40, 532 ±34 kg/
    m3
    , but that of
    E
    . globulus
    was large as 595 ± 69, 616 ± 79 kg/
    m3
    and the basic density was higher in bark side and upper part in the trunk, to be expected to have higher pulp productivity.
    The whole-tree values of
    E
    . camaldulensis
    were 501, 520 kg/
    m3
    and those of
    E
    . globulus
    were 594, 640 kg/
    m3
    and the difference of the species was observed.
    Representative heights for the whole-tree contents ±5 % were 0.32.
    8
    m on
    E
    . camaldulensis
    , and 0.
    8
    and 2.
    8
    m on
    E
    . globulus
    regardless the differences in the whole-tree height and the within-tree variation when they were chosen below
    3
    .
    3
    m height for sampling an increment core.
    Representative heights were also determined for contents of wood components per volume as follows ; for
    E
    . camaldulensis
    , holocellulose : 1.
    3
    , 2.
    8
    m, cellulose : 2.
    83
    .
    3
    m, hemicellulose : 0.
    82
    .
    8
    m, lignin : 0.81.
    3
    , 2.
    8
    m, extractives : 2.
    3
    m, alkali-extractives : 1.
    3
    m, and total-extractives : 2.32.
    8
    m, for
    E
    . globulus
    , 2.
    8
    m, 2.32.
    8
    m, 2.
    8
    m, 0.30.
    8
    m, 2.
    83
    .
    3
    m, 2.
    83
    .
    3
    m and 2.
    8
    m in the same manner.
    It is expected that whole-tree pulp properties including pulp productivity are predicted by the increment core taken from these representative heights.
  • 大石 勉, 木村 規
    高分子論文集
    1976年 33 巻 3 号 141-146
    発行日: 1976/03/25
    公開日: 2010/02/26
    ジャーナル フリー
    N-(2-フルオレニル) -マレイミド (I), N-1-(4-アセトキシナフチル) -マレイミド (II), N-2-(9-アセトキシフルオレニル) -マレイミド (III) の単独重合, 共重合をアゾビスイソブチロニトリル (IV) を開始剤としてテトラヒドロフラン中, 60℃で行った. 単独重合の初速度 (Rp) は, Rp=k [I] 2.11 [IV] 0.64, Rp=k [II] 2.26 [IV] 0.72, Rp=k [III] 1.76 [IV] 0.52となった. kは速度定数である. 全重合の活性化エネルギー (
    E
    ), 頻度係数 (A) は
    E
    =26.4kcal/mol (I), 23.
    3
    kcal/mol (II),
    22
    .
    8
    kcal/mol (III), A=
    3
    .4×1015 (I), 2.7×1011 (II), 1.5×1011 (III) となった. またN置換マレイミドとメタクリル酸メチル (V) との共重合におけるモノマー反応性比, Q,
    e
    値を次のように決定した.
    I (M1) -V (M2) 系で, r1=0.24, r2=0.
    93
    , Q1=0.43,
    e1
    =1.
    82
    , II (M1) -V (M2) 系で, r1=0.17,
    r22.29
    , Q1=0.51,
    e1
    =1.37, III (M1) -V (M2) 系で, r1=0.068, r2=1.34, Q1=0.87,
    e1
    =1.90となった.
  • 荻野 周次
    日本畜産学会報
    1928年 3 巻 81-87
    発行日: 1928年
    公開日: 2008/03/10
    ジャーナル フリー
    The relationship between withers height and hip height of 378 purebred Holstein-Friesian cows in Japan aged over 4, which have good dairy conformation and heigh milk production, is investigated by the Writer from biometric standpoint. And the results are as follows:
    1. Biometric constants.
    Withers height. (c.m.) Hip height. (c.m.)
    M……135.
    93
    ±0, 167 137.33±0.184
    σ……4.
    82
    ±0.118 5.29±0.130
    V……
    3
    .55±0.087
    3
    .85±0.095
    Q……
    3
    .17±0.228
    3
    .45±0.250
    Mi……135.40±0.210 136.90±0.230
    Mo……137.00±0.205 139.00±0.225
    S……-0.
    22
    ±0.042 -0.32±0.042
    2. The frequency curve of withers height is Y=378/4.
    82
    √2π
    e
    -1/2(χ-135.
    93
    /4.
    82
    )2×2, and that of hip height Y=378/5.29√2π
    e
    -1/2(χ-137.33/5.20)×2.
    3
    .The correlation coefficient between there two characters is +0.96±0.003.
    4.The regression equations are (denoting withers height and hip height by X and Y, respectively).
    X=0.88Y+16.45……(1)
    Y=1.05X-5.40……(2)
  • 高木 徹, 林 賢治, 板橋 豊
    日本水産学会誌
    1984年 50 巻 8 号 1413-1418
    発行日: 1984/08/25
    公開日: 2008/02/29
    ジャーナル フリー
    The acetone extracts from three samples of the hepatopancreas of the poisonous scallops obtained on the Okhotsk Coast of Hokkaido Island were fractionated into two parts, hexane soluble fraction (fraction H) and 85% aqueous ethanol soluble fraction (fraction
    E
    ) by partition to two layers. The majortoxic components in the mouse assay of “diarrheic shellfish toxin” by intra-peritoneal injection were found to be free unsaturated fatty acids showed the following toxicity in MU per g, 18:1 n-9 35, 18:2 n-6
    83
    , 18:
    3
    n-
    3
    167, 18:4 n-
    3
    83
    , 20:5 n-
    3
    167, and
    22
    :6 n-
    3
    83
    , respectively. Toxicity of the fraction Hin MUper g was much lower than that of the fraction
    E
    . However, the toxicity of the fraction H per 1 g of the hepatopancreas was about twice that of the fraction
    E
    , since the fraction Hwas much more abundant than the fraction
    E
    in the hepatopancreas. The method for the assay of the diarrhetic shellfish toxin must be reexamined by considering the toxic effect of the free unsaturated fatty acids.
  • Atsushi Irie, Hideo Kubo, Motonori Hoshi
    The Journal of Biochemistry
    1990年 107 巻 4 号 578-586
    発行日: 1990年
    公開日: 2008/11/18
    ジャーナル フリー
    Glucosylceramide (G1cβ1-1Cer) was isolated from the spermatozoa of the starfish, Asterias amurensis. The long-chain bases of the glycolipid consisted of dihydroxy (d18:2, d18:
    3
    , d19:
    3
    , and d
    22
    :2), and trihydroxy (t
    22
    :1) types. Long-chain aldehydes derived from them were analyzed mainly by proton nuclear-magnetic resonance to determine the detailed structures. Two of the tri-unsaturated bases were identified as (
    4E
    ,
    8E
    ,
    10E
    )-2-amino-4,
    8
    , 10-octadecatriene-1,
    3
    -diol (d18:
    3
    ) and (
    4E
    ,
    8E
    ,
    10E
    )-2-amino-9-methyl-4,
    8
    , 10-octa-decatriene-1,
    3
    -diol (d19:
    3
    ), which is a novel base. Both d
    22
    :2 and t
    22
    :1 had a cis double bond at the C9 or C13 position. All fatty acids were 2-hydroxylated (C14-C25):Most of themwere saturated and unbranched. About 10% was mono-unsaturated and unbranched (
    C22
    -C25), while saturated but branched (iso- and anteiso-types) C15-C18 acids were found as mi-nor components. The main fatty acids, which summed up to more than
    93
    % of the fatty acids in the glucosylceramide, were n-14h: 0, n-15h:0, n-16h : 0, n-17h : 0, n-18h : 0, and n-24h:1.
  • 川又 紀彦, 渡部 良平
    臨床血液
    2019年 60 巻 7 号 767-772
    発行日: 2019年
    公開日: 2019/08/06
    ジャーナル 認証あり

    BCR-ABL1 International Scale(IS)測定はチロシンキナーゼ阻害剤で治療されている慢性骨髄性白血病(CML)患者の治療効果をモニターする上で重要な検査法である。稀ではあるが,BCR-ABL1 IS測定ができないCMLが存在することが知られている。本研究において,我々は,そのようなBCR-ABL1 IS測定のできないCML患者を経験し,分子生物学的な方法で,その原因を解明した。本例ではABL1遺伝子における切断点がa2エクソン内にあることが分かり,そのことがABL1のa2エクソンを欠いた

    e
    14a
    3
    b
    3
    a
    3
    )キメラ遺伝子のmRNAのみの発現を誘導していた。a2エクソンは本邦における検査部でのIS測定において重要な要素であり,これが欠損することが測定不能の原因であった。このようなIS測定ができない稀なCML症例をさらに集積して,その分子構造を解明することが待たれる。

  • Yosizo YAMAMOTO
    Nippon Sugaku-Buturigakkwai Kizi Dai
    3
    Ki

    1940年 22 巻 12 号 1048-1052
    発行日: 1940年
    公開日: 2009/06/09
    ジャーナル フリー
    The numerical values of the intervals betrween optieal levels are competed for the configurations
    1s22s22p83s23p83
    *94s, 5s, 6s and 7s of Cu+, according to the general expression of energy-levels derived in the previous paper The self-consistent field radial functions computed by Hartree adn Hartree are used for1s, 2s, 2p,
    3
    s,
    3
    p and
    3
    d. Those of 4s, 5s,
    e
    .s and are ealenlated from Hartree Hartree's core-functions by the numerical integrations. The calculated results are shown in Table I.The agreement with experiment is satisfactory
  • Enbo Ma, Hiroyasu Iso, Kazumasa Yamagishi, Masahiko Ando, Kenji Wakai, Akiko Tamakoshi
    Journal of Epidemiology
    2018年 28 巻 9 号 388-396
    発行日: 2018/09/05
    公開日: 2018/09/05
    [早期公開] 公開日: 2018/05/26
    ジャーナル オープンアクセス

    Background: Oxidative stress, the imbalance between pro- and antioxidants, has been implicated in the etiology and pathophysiology of the incidence and mortality of many diseases. We aim to investigate the relations of dietary intakes of vitamin C and

    E
    and main carotenoids with all-cause mortality in Japanese men and women.

    Methods: The Japan Collaborative Cohort Study for Evaluation of Cancer Risk had

    22
    ,795 men and 35,539 women, aged 40–79 years at baseline (1988–1990), who completed a valid food frequency questionnaire and were followed up to the end of 2009.

    Results: There were 6,179 deaths in men and 5,355 deaths in women during the median follow-up of 18.9 years for men and 19.4 years for women. Multivariate hazard ratios for the highest versus lowest quintile intakes in women were 0.

    83
    (95% confidence interval [CI], 0.76–0.90; P for trend < 0.0001) for vitamin C, 0.85 (95% CI, 0.78–0.
    93
    ; P for trend < 0.0001) for vitamin
    E
    , 0.88 (95% CI, 0.81–0.96; P for trend = 0.0006) for β-carotene, and 0.90 (95% CI, 0.
    82
    –0.98; P for trend = 0.0002) for β-cryptoxanthin. The joint effect of any two of these highly correlated micronutrients showed significant 12–17% reductions in risk in the high-intake group compared with the low-intake group in women. These significant associations were also observed in the highest quintile intakes of vitamin C, vitamin
    E
    , and β-carotene in female non-smokers but were not observed in female smokers, male smokers, and non-smokers.

    Conclusions: Higher dietary intakes of antioxidant vitamins may reduce the risk of all-cause mortality in middle-aged Japanese women, especially female non-smokers.

  • Hin-chung Wong, Chia-Yun Ho, Li-Ping Kuo, Tien-Kuei Wang, Chi-Lung Lee, Daniel Yang-Chih Shih
    MICROBIOLOGY and IMMUNOLOGY
    1999年 43 巻 7 号 631-636
    発行日: 1999年
    公開日: 2008/03/17
    ジャーナル フリー
    Vibrio parahaemolyticus is a prevalent food-borne pathogen in Taiwan, Japan and other Asian countries. This work presents a novel ribotyping method for the molecular epidemiological examination of this pathogen. Genomic DNA was fragmented by HindIII digestion and hybridized with cDNA probe for Escherichia coli 16S and 23S RNA genes. A total of 121 isolates obtained from outbreaks during 1992 and 1994 in Taiwan were characterized by this ribotyping method. Four to seventeen restricted fragments were visualized in these isolates. After hierarchical cluster analysis, these isolates were grouped into thirty different ribotypes. In addition, A
    3
    , A7,
    E
    3
    and F1 were the major ribotypes, consisting of
    22
    .
    3
    , 13.2, 9.1, and
    8
    .
    3
    % of the isolates, respectively. A,
    E
    , F, G and
    B
    were the major groups, consisting of 46.2, 14.0, 9.1, 6.7, and 6.7% of the isolates, respectively. The discriminatory ability of this ribotyping method, as determined by Simpson's index of diversity, was 0.
    93
    , which closely resembled that of a previously reported pulsed-field gel electrophoresis method.
  • 第1報 夏季雨量の1ヵ月予報
    山本 武夫
    気象集誌. 第2輯
    1961年 39 巻 1 号 29-44
    発行日: 1961/12/28
    公開日: 2007/10/19
    ジャーナル フリー
    The monthly amount of summer Precipitations in Japan can be possibly forecasted by the 200mb height circulation trends in the preceeding month. The differences of monthly mean 200mb gpm, for instance, [Shionomisaki (33°27'N, 135°46'
    E
    )- Wajima (37°23'N, 136°54'
    E
    )] in June, show surprising correlations with the amount of precipitations in July at many places and various districts in Japan, and the correlation coefficients with July precipitations, for example, of the western part of Japan and Hokkaido, are as follows.
    (a) The total amount of July precipt. at 5 places in western Japan ;
    Fukuoka (33°35'N, 130°23'
    E
    ), Oita (33°14'N, 131°37'
    E
    ), Shimonoseki (33°57'N, 130°56'
    E
    ), Hagi (34°25'N, 131°24'
    E
    ), and Hofu (34°03'N, 131°32'
    E
    ).
    R=+0.
    93
    for the years of period (1950-1459, n=10)
    (
    b
    ) The total amount of July precipt, at 5 places in Hokkaido ;
    Suttsu (42°47'N, 140°14'
    E
    ), Sapporo (43°03'N, 141°20'
    E
    ), Asahikawa (43°46'N, 142°
    22
    '
    E
    ), Haboro (44°
    22
    'N, 141°42'
    E
    ), and Wakkanai (45°25'N, 141°41'
    E
    ).
    R=-0.
    83
    for the years of period (1950-1959, n=10)
    As shown in Fig. 4 (A), above normal strength of mean jet streams in southern part of Japan is related contemporarily to the rainfall distribution, above normal in southwestern part of Japan and below normal in Hokkaido, and vice versa. Because of persistence of the tendency to maintain itself in a given state of circulation in upper air, the zonal index at 200mb height adequately adopted for the stations in southern part of Japan, may be presumed to be closely related to the precipitations in the following month.
    As a test of stability of the forecasting relationships, which were obtained from the data in the recent only 10 years or so, since the establishment of systematic upper air observations in Japan, it is investigated that below normal air temperatures in early summer from April to June at mountain observatories in western Japan, which suggest the upper air flow patterns with deep trough over the Japan Sea and above normal strength of mean jet over the southwestern part of Japan, tend to be favorable to above normal July precipitations in the western Japan and vice versa. The correlation coefficient of the mean air temperatures of April, May and June at Hieizan (35°03'N, 135°50'
    E
    , 832m) with the amount of July precipitations in the district along the Inland Sea [totals for 5 places, Shimonoseki, Matsuyama (33°50'N, 132°47'
    E
    ), Hiroshima (34°
    22
    'N, 132°26'
    E
    ), Okayama (34°41'N, 133°55'
    E
    ), and Tadotsu (34°16'N, 133°45'
    E
    )] is R=-0.51 (for the years of period 1929-1947, n=19), while the coefficient of June air temperature at Asosan (32°53'N, 131°05'
    E
    , 1143m) with the July precipitations in the western part of Kyushu [totals for 4 places, Izuhara (34°12'N, 129°18'
    E
    ), Tomie (32°37'N, 128°46'
    E
    ), Nagasaki (32°44'N, 129°53'
    E
    ), and Unzendake (32°44'N, 130°15'
    E
    )] being R=-0.49 (for the period 1923-1952, n=20).The results of applications of the relationships to the forecasting of monthly amountof rainfalls in May, June and July in this year are very satisfactory, as seen inFig.9 (A), (
    B
    ), (C).
  • 斉 洋之, 高津戸 秀, 池川 信夫
    Chemical and Pharmaceutical Bulletin
    1985年 33 巻 11 号 4815-4820
    発行日: 1985/11/25
    公開日: 2008/03/31
    ジャーナル フリー
    Two new vitamin
    D3
    analogues, 1α-hydroxy-24, 24-dimethyl-
    22
    E
    -dehydrovitamin
    D3
    (13) and 1α, 25-dihydroxy-24, 24-dimethyl-
    22
    E
    -dehydrovitamin
    D3
    (17), which are blocked for 24-hydroxylation by the methyl groups, were synthesized from 1α,
    -bismethoxymethoxypregn-5-ene-20Scarbaldehyde (6) by using the orthoester Claisen rearrangement for construction of the carbon skeleton of their side chains. These compounds (13 and 17) elicited a rise in serum calcium, but not in serum inorganic phosphorus in rats. In a bioassay for alkaline phosphatase, they were found to show much weaker activity than 1α-hydroxy vitamin
    D3
    (5).
  • Tsuguru Shirakawa, Chihiro Hamaguchi, Junkichi Nakai
    Journal of the Physical Society of Japan
    1973年 35 巻 4 号 1098-1105
    発行日: 1973/10/05
    公開日: 2007/06/01
    ジャーナル 認証あり
    Magnetophonon resonances, which were first predicted by Gurevich and Firsov, have been observed in the hot electron mobility in pure n-InSb. The resonance experiment was carried out at 77 K in transverse magnetic field up to
    22
    kG with application of sufficiently small electric field to produce a slight change in the electron mobility. The quantity β in the formula μ=μ0(1−βE2) was measured with extremely good accuracy (Δμ⁄μ0∼10−7) by adopting a bridge circuit. The minima in the quantity |β| were observed at magnetic fields,
    B
    =17.5, 11.
    3
    ,
    8
    .53, 6.89, 5.72, 4.
    83
    , 4.12,
    3
    .68,
    3
    .72, and 2.
    93
    kG. These resonance extrema are attributed to resonant cooling of hot electrons due to optical phonon induced transitions from the high energy tail of the electron distribution near kz=0 at higher Landau levels to lower Landau levels. The extremal positions are well explained by taking the non-parabolicity of the conduction band of InSb into account.
  • H. K. Mahanty
    CYTOLOGIA
    1970年 35 巻 1 号 13-49
    発行日: 1970/03/25
    公開日: 2009/03/19
    ジャーナル フリー
    1. The chromosome numbers of 64 species have been studied on which 56 are investigated for the first time.
    2. Morphological, anatomical and cytological findings on the Musaceae in the broad sense are considered from a phylogenetical standpoint and three distinct groups:
    a) Musa-Ensete,
    b
    ) Ravenala-Strelitzia-Phenakospermum and c) Holiconia are recognised as suggested by some authors. For these groups sub-familial status is proposed.
    3
    . Lowiaceae have been studied for the first time cytologically and their chromosome morphology, distinct from that of any other group of Zingiberales, confirms their claim to familial status.
    4. Consideration of the conflicting theories proposed to account for the higher chromosome number in genera like Globba, Alpinia, and Phaemeria, etc. leads to rejection of Chakravorti's hypothesis of wholesale fragmentation of chromosomes and the acceptance of the opposed view of Raghavan and Venkatasubban and others.
    5. Holttum's transference of the genus Zingiber to the tribe Hedychieae has been given cytological support on the following points:
    a) the basic number in the genus Zingiber correlates with that of Kaempferia.
    b
    ) the new tribe Alpinieae (which is infact Zingibereae without Zingiber) have consistently 48 chromosomes in their somatic complements.
    6. It is suggested that the African representatives of Kaempferia should be given the status of genus; Cienkowskya on the following points:
    a) the difference in floral morphology
    b
    ) geographical separateness and
    c) the difference in the number and morphology of the chromosomes. By comparing the present and past findings, various lines of evolution of the chromosome complements within each group are discussed.
    7. The basic number 11 is considered to be probably the original one for the Zingiberales as a whole, being present in Ravenala which is the most primitive member in the order. From this secondary basic numbers have arisen through evolution.
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