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  • Grover Loening
    日本航空学会誌
    1963年 11 巻 119 号 373-380
    発行日: 1963年
    公開日: 2009/05/25
    ジャーナル フリー
  • Suguru TAKATSUTO, Kiyomi KOBAYASHI, Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE
    Agricultural and Biological Chemistry
    1988年 52 巻 12 号 3217-3218
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • Mohd Suhail, Mohd Faizul Suhail, Hina Khan
    Journal of Clinical Biochemistry and Nutrition
    2008年 43 巻 3 号 210-220
    発行日: 2008年
    公開日: 2008/10/31
    ジャーナル フリー
    We compared three groups of pregnant women: placebo with normotensive women, group A which included preeclamptics, and group
    B
    which comprised preeclamptics who were supplemented their diets with vitamins C and
    E
    . MDA increased from 6.
    22
     ± 2.
    8
    (placebo) to
    8
    .48 ± 1.2 (A) and
    8
    .02 ± 1.
    8
     nmol/gHb (
    B
    ). NO concentrations were enhanced from 19.3 ± 
    4
    .2 (P) to 23.
    8
     ± 6.
    4
    (A) and 24.1 ± 
    5
    .
    4
     μmol/L (
    B
    ). GSH contents were decreased from 10.42 ± 2.81 (P) to
    8
    .02 ± 2.92 (A) and 9.39 ± 1.02 μmol/g Hb (
    B
    ), whereas GSSG concentrations increased from 0.
    98
     ± 0.28 (P) to 1.24 ± 0.29 (A) and 1.08 ± 0.12 μmol/g Hb (
    B
    ). SOD activity decreased 23% in A and 14% in
    B
    ; GRx decreased 27% in A and
    5
    .
    5
    % in
    B
    ; GPx decreased 12% in A and 9.6% in
    B
    . Catalase activity, however, increased 27% in A and 29% in
    B
    as compared to control. Thus, we conclude that the use of vitamins C and
    E
    should be considered for the control of certain important biochemical indices during the development of preeclampsia; however, further studies are needed to develop methods for the prevention of preeclampsia in women at high risk.
  • 小田切 孝人, 田代 眞人
    ウイルス
    2013年 63 巻 2 号 233-240
    発行日: 2013/12/25
    公開日: 2014/10/31
    ジャーナル フリー
  • Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE, Kiyomi KOBAYASHI, Suguru TAKATSUTO
    Agricultural and Biological Chemistry
    1988年 52 巻 8 号 2117-2118
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • Yukichi Yamaguchi, Jian-zhi Runan(Gen), Teruaki Nagahara
    Journal of the Physical Society of Japan
    1975年 38 巻 4 号 911-916
    発行日: 1975/04/15
    公開日: 2007/06/01
    ジャーナル 認証あり
    The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the 116mIn activity. Directional correlations are also measured for 818–1293 and 1097–1293 keV cascades. The M1-
    E
    2 mixing ratio δ, and the
    E
    0-
    E
    2 mixing ratio μk are obtained for 818.7 keV
    22
    +→21+ transition to be δ=1.52
    0.22
    +0.26, and μk≤6.1×10
    4
    respectively. The
    E
    2 branching ratio
    B
    (
    E
    2;
    22
    +
    →0g+):
    B
    (
    E
    2;
    22
    +→21+):
    B
    (
    E
    2;
    22
    +→01+) is determined to be 0.0158:1.0:
    5
    .86.
  • 永幡 肇, 舟橋 敏行, 野田 寛
    日本獸醫學雜誌(The Japanese Journal of Veterinary Science)
    1984年 46 巻 6 号 815-821
    発行日: 1984/12/15
    公開日: 2008/02/13
    ジャーナル フリー
    ウシリンパ球の
    E
    -ロゼット法の成績に影響する諸要因を検討し, 本法を標準化するため用いる羊血球の品種および個体差, 処理法 (ノイラミニダーゼ(EN), 2-アミノエチルイソチオウロニウムブロマイド(EAET)), ロゼットメディウム, T,
    B
    両マーカーをもつリンパ球について検討し, 正常牛リンパ球のサブポピュレーションをしらべた。サフォーク種, コリデール種および雑種の血球間でのロゼット形成率(RFC)には差を認めなかった。処理(EN, EAET) 血球のRFCは無処理血球のそれに比べ有意に高かった (P<.01,<.01)。標準法としては, 20%FCS 加 Eagle's MEMリンパ球 (3-
    4
    ×106ml)浮遊液とAET処理1%羊赤血球デキストラン (
    8
    %デキストラン, Mol.wt. 177000)浮 遊液とを等量(400μ1)混合し, 37℃, 30分反応後遠心し,
    4
    ℃, 16~20時間静置後の算定が適当であった。本法による
    E
    -ロゼット法, 蛍光標識抗ウシIgGを用いた表面免疫グロブリンの測定およびイースト粒子取込み法による単球の同定法により, 正常牛
    8
    頭の末梢血単核細胞をTリンパ球 (61.
    4
    ±3.9%, 56-68%),
    B
    リンパ球 (
    22
    .
    8
    ±
    4
    .1%, 16-30%), 単球 (6.1±2.6%,
    4
    -10%) に分別し得た。T,
    B
    両マーカーをもつリンパ球は約3% (0-6%) 認められた。
  • Sen-fang Sui, Erich Sackmann
    The Journal of Biochemistry
    1992年 111 巻 1 号 129-138
    発行日: 1992年
    公開日: 2008/11/18
    ジャーナル フリー
    In the first part of the present work the interaction of glycophorin with dimyristoylphosphatidylcholine (DMPC) is studied by freeze fracture electron microscopy, densitometry, calorimetry, and 90° static light scattering. An exothermic lipid/protein interaction energy of WP=190 kJ•mol-1 was found by application of the well known Van Laar relation for the displacement of the freezing point and the Gibbs-Duhem relationship. Secondly, the effects of Ca2+ on the lipid/protein interaction were studied. Following Ca2+ addition a remarkable decoupling of the interaction of the glycophorin head group with the bilayer surface was revealed by densitometry and gold-labeling electron microscopy. It is estimated that about 80% of lipid once disturbed by the adsorption of glycophorin head groups is decoupled after addition of Ca2+. Thirdly, the selective interaction of glycophorin with binary lipid mixtures was studied, including the mixtures of DMPC with dimyristoylphosphatidylserine (DMPS) and dilauroylphosphatidylcholine (DLPC), and the mixture of dipalmitoylphosphatidylcholine (DPPC) with DLPC.
  • 香山 滉一郎, 森下 政夫, 張 国鋒
    粉体および粉末冶金
    2006年 53 巻 5 号 419-429
    発行日: 2006年
    公開日: 2006/12/19
    ジャーナル オープンアクセス
    The phase diagrams of the Ni-Mo-
    B
    and Ni-W-
    B
    ternary systems in the region of less than 50mol%
    B
    were constructed by thermodynamic calculation, based on the data obtained by thermodynamic measurement of the related materials. We found three ternary eutectic points and three or two ternary peritecto-eutectic points as follows:
    E1
    :L (1365K, 71.
    5
    mol%Ni-6.0mol%Mo-
    22
    .
    5
    mol%
    B
    )=(Ni)+
    Ni3B
    +
    NiMo2B2

    E2
    :L (1355K, 62.
    5
    mol%Ni-2.
    5
    mol%Mo-30.
    5
    mol%
    B
    )=
    Ni3B
    +
    Ni2B
    +
    NiMo2B2

    E3
    :L (1445K, 42.0mol%Ni-30.6mol%Mo-10.3mol%
    B
    )=(Ni)+NiMo+
    NiMo2B2

    P1:L (1812K, 34.9mol%Ni-42.3mol%Mo-
    22
    .
    8
    mol%
    B
    )+MoB=
    Mo2B
    +
    NiMo2B2

    P2:L (1633K, 42.3mol%Ni-40.
    4
    mol%Mo-17.3mol%
    B
    )+Mo=
    Mo2B
    +
    NiMo2B2

    P3:L (1812K, 53.
    5
    mol%Ni-33.7mol%Mo-12.
    8
    mol%
    B
    )+Mo=NiMo+
    NiMo2B2

    E1
    :L (1622K, 51.0mol%Ni-31.6mol%W-17.
    4
    mol%
    B
    )=(Ni)+W+
    NiW2B2

    E2
    :L (1260K, 71.0mol%Ni-7.0mol%W-
    22
    .0mol%
    B
    )=(Ni)+
    Ni3B
    +
    NiW2B2

    E3
    :L (1291K, 65.
    4
    mol%Ni-
    4
    .
    8
    mol%W-29.
    8
    mol%
    B
    )=
    Ni2B
    +
    Ni3B
    +
    NiW2B2

    P1:L (2115K, 23.
    8
    mol%Ni-43.1mol%W-33.1mol%
    B
    )+WB=
    W2B
    +
    NiW2B2

    P2:L (1657K, 48.9mol%Ni-33.1mol%W-18.0mol%
    B
    )+
    W2B
    =W+
    NiW2B2

    The calculated phase diagrams are expected to be useful for the development of new Ni-based heat-, corrosion- or wear-resistance alloys.
  • Kazuo TAKEUCHI, Masayuki ATSUCHI, Shoji ODA, Minoru JINBO, Takeshi MASUI, Motohide OGASHIWA
    Neurologia medico-chirurgica
    1968年 10 巻 132-133
    発行日: 1968年
    公開日: 2007/08/17
    ジャーナル フリー
  • Özkan ASLANTAŞ, Ebru Şebnem YILMAZ
    Journal of Veterinary Medical Science
    2017年 79 巻 6 号 1024-1030
    発行日: 2017年
    公開日: 2017/06/16
    [早期公開] 公開日: 2017/04/27
    ジャーナル フリー

    This study aimed to determine the prevalence of fecal carriage of extended spectrum β-lactamase (ESBL) and/or plasmidic AmpC β-lactamase (pAmpC) producing Escherichia coli among dogs (n=428) in Turkey. Polymerase chain reaction (PCR) and sequencing were used to characterize genes encoding β-lactamase and plasmid mediated quinolone resistance (PMQR). Antimicrobial susceptibility testing and PCRs for virulence genes and phylogenetic groups were also performed. Cefotaxime resistant

    E
    . coli isolates were detected in 95 (
    22
    .2%) of the swab samples. Sequencing analysis results showed occurrence of various β-lactamase genes: blaCTX-M-15 (62), blaTEM-
    1b
    (42), blaCMY-2 (
    22
    ), blaCTX-M-3 (16), blaCTX-M-1 (15), blaOXA-1 (9) and blaSHV-12 (3) alone or in combination. The most frequently encountered phylogenetic group was group A1 (35.
    8
    %), followed by group D2 (
    22
    .1%),
    B
    1 (15.
    8
    %), D1 (9.
    5
    %), A0 (7.
    4
    %),
    B22
    (
    5
    .3%) and
    B23
    (
    4
    .2%), respectively. PMQR genes, aac(6’)-Ib-cr, qnrS1 and qnrB10 were detected in 25.3, 10.
    5
    and 1.1% of the isolates, respectively. While all isolates were susceptible to imipenem and amikacin, resistance rates to non-β-lactam antibiotics ranged from 20.0% for tobramycin to 56.
    8
    % for tetracycline. The virulence genes were only detected in 34 (36.2%) of the isolates and this isolates carried single or various combination of virulence genes of iucD, papC, papE, f17a-A and eaeA. Four isolates were identified as human virulent pandemic CTX-M-15 producing
    E
    . coli
    clone O25
    b
    :ST131/
    B
    2. To the best of our knowledge, this is the first study to show fecal carriage of ESBL/pAmpC type β-lactamase producing
    E
    . coli
    isolates among dogs in Turkey.

  • 佐藤 敬之輔
    デザイン学研究
    1970年 1970 巻 11 号 45-55
    発行日: 1970/03/30
    公開日: 2017/07/25
    ジャーナル フリー
    [1] The purpose of this reserch is to make clear what type of design can give good effects to win the high readership score. At the begining I had to know what factors decide the readership score, and how to change the quality of the desing into numerical value. I have used the method of multi-dimentional analysis with the help of a computer, and got the estimation formula, with 7 kinds of factors, as follows ; A^^〜=
    B
    +C+D+K+
    aE
    +bF+cG. A^^〜=estimated values of the readership score. 1)
    B
    , C, D, K : these four factors are given as category values (so we call them); each factor is classified into several categories.
    B
    =week day, classified into 7 categories. C=pages of a newspaper, which are characterized by the kinds of articles, news, and the other reading matters, classified into
    22
    categories. D=kinds of goods and trades of the advertizement, classified into 14 catedories. K=constants, given to each 13 surveys. 2)
    E
    , F, G : these factors are given as numerical values. G=area of advertizement, measured by the unit of column in the whole page length, being classified into 6 kinds of area (2.
    5
    , 3.
    5
    ,
    5
    , 7, 10, 15) and 15 column means a whole page, about 2,000cm^2.
    E
    , F are the marks obtained in the design of advertizements.
    E
    =sum of the marks obtained in each design element on the advertizement. F=the marks obtained on the whole effect of the design. 3) a,
    b
    , c : coefficients Using the above formula with the category values and the coefficients, we can obtain the naked design effect from the actual value A of readership score:
    aE
    +bF=A-(
    B
    +C+D+K+cG). In this research, I used 1,829 data of readership score from 1960 to 1968, being obtained by 13 survevs, spring and autumn twice a year. The sample of size each survey was 3,541, 2,251, or 200 in the other 11 surveys. Multiple correlation coefficient between the estimated value A^^〜 and the actual value A is 0.951. The table 2^* shows the contribution indexes of each factor by 3 kinds of expression-(1) Range : the absolute difference between the maximum and the minimum category values, (2) Standard deviations of the category values, (3) Partial correlation coefficient : the relationship between the actual values A and each factors. *see the table 2 in the thesis in Japanese. [2] The important point was in the determination of the values of
    E
    , F.
    E
    is the sum of the marks obtained in each design element, classified into four kinds :
    E
    =
    E
    _1+
    E
    _2+
    E
    _3+
    E
    _
    4
    . design elements [table]
    E
    _1,
    E
    _2,
    E
    _3,
    E
    _
    4
    , these values have the
    5
    grades, as 0, 1, 2, 3,
    4
    and 0 is given to the design that has no attractive effect or no applicable element. And
    E
    obtain the marks of 0 to 9 grades as the sum of them. The values of F have also
    5
    grades, 0 to
    4
    . The principles to determine the values of
    E
    , F are as follows : a) The marks obtained of
    E
    , F must be the relative values among the each survey, and at the same time, they must have constancy within the same survey-the same elements of design must win the same marks obtained.
    b
    ) They must be determined as to win the highest multiple correlation coefficient, when they are put into the estimation formula. c) They must be reasonable. In order to justify them, we must carry many researches on the actual condition. The frequency of accurence of each grade of
    E
    , F values, as the table
    5
    -
    4
    , and
    5
    -
    5
    in the thesis in Japanese.
  • 高津戸 秀, 池川 信夫
    Chemical and Pharmaceutical Bulletin
    1984年 32 巻 5 号 2001-2004
    発行日: 1984/05/25
    公開日: 2008/03/31
    ジャーナル フリー
    Brassinolide analogues, (
    22
    R, 23R, 24R)-2α, 3α,
    22
    , 23-tetrahydroxy-
    B
    -homo-7-oxa-
    -ergostan-6-one (24-epibrassinolide) (10) and (
    22
    S, 23S, 24R)-2α, 3α,
    22
    , 23-tetrahydroxy-
    B
    -homo-7-oxa-
    -ergostan-6-one (9), were synthesized from brassicasterol (3a) in five steps and with ca. 20% overall yield. The key steps are the direct formation of (
    22
    E
    , 24R)-3α,
    5
    -cyclo-
    -ergost-
    22
    -en-6-one (
    4
    ) from brassicasterol mesylate (3
    b
    ), the acid-catalyzed rearrangement of
    4
    to (
    22
    E
    , 24R)-
    -ergosta-2,
    22
    -dien-6-one (6), and the Baeyer-Villiger oxidation of the tetrahydroxy
    -ergostan-6-ones 7 and
    8
    .
  • 東畑 郁生, PRASAD S.K., 本多 剛, CHANDRADHARA G.P.
    地盤工学会論文報告集
    2002年 42 巻 4 号 77-88
    発行日: 2002/08/15
    公開日: 2008/02/29
    ジャーナル フリー
    The Gujarat earthquake in India occurred in January, 2001, and caused significant damage in the province of Gujarat. The Japanese Geotechnical Society sent a small reconnaissance team to the damaged region after the quake. The present text presents the report from this activity. The major attention of the team was focused on geotechnical aspects of the damage which were related to earthfill dams and harbor land fills. It was found that a significant portion of damage was concentrated in fills resting on soft natural soils. Swedish weight soundings which were conducted at two places demonstrated the existence of such a soft subsoil. From this, it was concluded that amplification of earthquake shaking as well as the permanent deformation in the soft foundation soil induced such kinds of damage as subsidence, cracking, and lateral spreading in overlying artificial fills. For the better seismic resistance of those affected fills during future earthquakes, the improvement of soft subsoil seems essential.
  • 蒋 通, 栗林 栄一
    土質工学会論文報告集
    1988年 28 巻 1 号 56-64
    発行日: 1988/03/15
    公開日: 2008/02/29
    ジャーナル フリー
    The boundary element method expanded in frequency domains is presented to analyze the dynamic interaction between an embedded flexible rectangular foundation and soil with consideration of the obliquely incident waves. Numerical results describing the influence of the flexibility of the foundation on the dynamic responses of the foundation due to obliquely incident waves indicate that the flexibility of actual foundations can diminish the reduction of translation responses and increase the rotational responses in the high frequency range. These phenomena are more conspicuous as the embedment ratio is larger and the value of the wave velocity ratio of the soil and the foundation approaches to unity. When the high frequency components of the input ground motion are important and the basement has higher flexibility (for example 2vs/1vs >0.
    4
    ), the analysis method which considers the basement as a rigid foundation may lead to unsafety estimations and the estimation of the flexibility of the foundation is necessary as analysing the effective input motion with consideration of the incident waves.
  • 山田 善一, 野田 茂
    土質工学会論文報告集
    1988年 28 巻 1 号 143-152
    発行日: 1988/03/15
    公開日: 2008/02/29
    ジャーナル フリー
  • 田口 平八郎, 池谷 幸信, 吉岡 一郎
    天然有機化合物討論会講演要旨集
    1979年 22 巻 40
    発行日: 1979/09/20
    公開日: 2017/08/18
    会議録・要旨集 フリー
    Three new dibenzocyclooctadiene lignans, epigomisin O(1), gomisin
    E
    (7) and angeloylgomisin Q(26), were isolated from the fruits of Schizandra chinensis BAILL.(Schizandraceae), which are used as an antitussive and a tonic under the names of "Hoku-gomisi" in Japan and "Wu-wei-zi" in China. 1) The structure of epigomisin O(1) was elucidated by correlation with known lignans, gomisins O(2) and N(
    4
    ). 2) Oxidation of
    4
    with KMnO_
    4
    in a mixture of 2% NaOH and pyridine gave compounds 3 and
    5
    . Further oxidation of 3 with KMnO_
    4
    gave
    5
    . Reduction of
    5
    with NaBH_
    4
    afforded deangeloylgomisin
    B
    (6). The structure of gomisin
    E
    (7) was elucidated by the same reaction to correlate with a known lignan, gomisin D(
    8
    ). 3) The cleavage of the methylenedioxy group on the aromatic ring with Pb(OAc)_
    4
    in dry benzene into diphenol was studied(19-
    22
    →19
    b
    -
    22
    b
    ). The structure of angeloylgomisin Q(26) was elucidated by the use of the above reaction to correlate with 6.
  • YOSHIO GOTO, TAKAYOSHI TOYOTA, YUTAKA ISHITOYA
    The Tohoku Journal of Experimental Medicine
    1974年 112 巻 3 号 279-284
    発行日: 1974年
    公開日: 2008/11/28
    ジャーナル フリー
    Blood sugar contents of three hundred and thirty blood specimens were determined by six different analytical methods, i.
    e
    ., the glucose-oxidase method (G), the autoanalyser method with Hoffman's method (A), the Somogyi-Nelson method (S), the o-toluidine method (T), the Momose's method (M) and the Hage-dorn-Jensen method (H). The values determined by micromethods of Hagedorn-Jensen, of Momose and of Somogyi-Nelson are usually higher, and the values obtained by o-toluidine method are mostly lower than those estimated by the glucose-oxidase method. The values determined by the autoanalyser method are most consistent with those of the glucose-oxidase method among the five analytical methods. With the values of six series, the regression equations were obtained as following: A=0.86 G + 13, S=0.90 G + 34, T=0.76 G +
    8
    , M=0.
    98
    G + 28, H=0.85 G + 40, S=1.02 A + 23, T=0.88 A-3, M=1.10 A + 17, H=0.
    98
    A + 26, T=0.75 S-7, M=0.99 S+
    4
    , H=0.
    83
    8
    +23, M=1.
    22
    T+24, H=0.78 M+26.
  • Keishi Hata, Fuyuki Sugawara, Naganori Ohisa, Saori Takahashi, Kazuyuki Hori
    Biological and Pharmaceutical Bulletin
    2002年 25 巻 8 号 1040-1044
    発行日: 2002年
    公開日: 2002/08/01
    ジャーナル フリー
    We screened the differentiation-inducing activities of 39 mushroom extracts from Akita prefecture, Japan, on the mouse osteoblastic cell line, MC3T3-
    E
    1. Sixteen phosphate buffered saline (PBS),
    8
    boiled PBS, 14 ethanol and 12 methanol extracts induced alkaline phosphatase (ALP) activities, an indicator of MC3T3-
    E
    1 cell differentiation. The enzyme activities were markedly induced by extracts of Tricholoma auratum, and we isolated the active compound from methanol extracts of this mushroom. Physical data for the isolated active compound were identical to those for (
    22E
    ,24R)-ergosta-7,
    22
    -diene-3β,
    ,6β-triol (1). 1 induced ALP activities of MC3T3-
    E
    1 cells and promoted cell proliferation. To investigate the relationships between the chemical structure and differentiation-inducing activity of the compound, ALP-inducing activities of MC3T3-
    E
    1 cells by 1, ergosterol (2), ergocalciferol (3), cholesta-3β,
    ,6β-triol (
    4
    ), 7-dehydrocholesterol (
    5
    ) and cholecalciferol (6) were tested. The enzyme activities of MC3T3-
    E
    1 cells were increased 3.0-fold by 10 μM 1 and 2.
    4
    -fold by 10 μM
    4
    . However, 2, 3,
    5
    and 6 did not induce MC3T3-
    E
    1 cell ALP activity at 0.1—10 μM. These results suggested that the OH groups at C-
    5
    and/or C-6 of 1 and
    4
    played an important role in their differentiation-inducing activities on MC3T3-
    E
    1 cells. Furthermore, 1 suppressed induction of MC3T3-
    E
    1 cell apoptosis by serum starvation.
  • Yasuyuki Gono, Manabu Fujioka, Tamotsu Toriyama
    Journal of the Physical Society of Japan
    1970年 29 巻 2 号 255-258
    発行日: 1970/08/05
    公開日: 2007/06/01
    ジャーナル 認証あり
    The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the Tb152 activity. The L-subshell electron lines of the 586.7 keV
    22
    +→21+ transition are separated by the ion-free beta-ray spectrometer. The M1-
    E
    2 mixing ratio, δ2, and the dimensionless ratio X of
    E
    0-
    E
    2 mixing of the 586.7 keV transition are obtained to be δ2≤0.16 and 0.034≤X≤0.038, respectively. The
    E
    2 branching ratio
    B
    (
    E
    2;
    22
    +→0g+):
    B
    (
    E
    2;
    22
    +→21+):
    B
    (
    E
    2;
    22
    +→01+) is determined to be 0.023 : 1.0 :
    5
    .6.
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