Two new partially saturated tricyclic ring systems, , a, , , , 10, 10a, 11-octahydro-11-oxodibenz [, ] oxepins (3a and 3), and -thiepins (4a and 4) were synthesized. Compounds 4a and 4 were desulfurized to give a pair of isomeric -methylbenzoylcyclohexanes (10a and 10). Deuterated 4a and 4 (11a and 11) were prepared starting from butadiene- (12). The stereochemical features of 3a (trans), 3 (cis), 4a (trans) and 4 (cis) are compared with those of 10a, 10, 11a and 11 on the basis of proton nuclear magnetic resonance data.

抄録全体を表示

One method currently being considered for the disposal of high level radio-active waste is burial in the seabed. When a hot object is buried in soil, the temperature of the soil adjacent to the object is raised and there is transient heat flow away from the object. The rise in the temperature of the soil causes excess pore pressures to be generated and transient pore water diffusion also takes place. A finite element formulation of the coupled heat flow and consolidation problem is presented. The computer implementation of this formulation is found to compare favourably with analytical solutions based on the same physical principles.

抄録全体を表示

The ability of Climacodon septentrionalis to immobilize and kill a mycophagous nematode (Aphelenchoides sp.) in vitro is described for the first time. Two isolates produced droplets (20–45 μm in diameter) that formed at the apices of tall, stalked, and branching secretory cells (700–1,500 μm tall). On

% modified malt extract agar, nematodes became enveloped in the droplets, which restricted their ability to move and resulted in complete immobilization and death within several hours of contact. The rate of decomposition of the nematodes varied considerably, with most individuals persisting for weeks whereas others were degraded within several days and appeared to be colonized by dense hyphal growth. This study provides the first documentation of a non-agaricoid fungus producing secretory cells that are able to immobilize nematodes.

抄録全体を表示

11-Amino-, a, , , , 10, 10a, 11-octahydrodibebenzo[, ]thiepines (a-d) and -oxepines (a-d) were synthesized by the Leuckart reaction of , a, , , , 10, 10a, 11-octahydro-11-oxodibenzo[, ]thiepines (1a, )and -oxepines (a, ) followed by hydrolysis of the reaction products 4a-d and a-d, respectively. The four diastereomers, cis(a-H, 10a-H)-cis(10a-H, 11-H) a and a, cis(a-H, 10a-H)-trans(10a-H, 11-H) and , trans(a-H, 10a-H)-trans(10a-H, 11a-H) and , and trans(a-H, 10a-H)-cis(10a-H, 11-H) d and d, were isolated and their configurations and conformations were elucidated by chemical methods together with ¹H-nuclear magnetic resonance spectroscopic and X-ray crystallographic analyses.

抄録全体を表示

The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the ^116mIn activity. Directional correlations are also measured for 818–1293 and 1097–1293 keV cascades. The M1- mixing ratio δ, and the 0- mixing ratio μ_k are obtained for 818. keV +→2₁⁺ transition to be δ=1.52−

0.22

+0.26, and μ_k≤

6

.1×10⁻⁴ respectively. The

E

2

branching ratio

B

(

E

2

;

2₂

+→0_g⁺):

B

(

E

2

;

2₂

+→2₁⁺):

B

(

E

2

;

2₂

+→0₁⁺) is determined to be 0.0158:1.0:

5

.

86

.

抄録全体を表示

A sample of [³H] tobrarnycin (, 000 Ci/Mole) has been synthetized and incubated with
the bacterial ribosome and its subunits. The results obtained show that this antibiotic has
two types of binding sites. The primary one is probably responsible for the inhibition of
protein synthesis whereas the secondary one is probably related to the misreading and reading
tiirough of the messenger RNA.

抄録全体を表示

The possibility of attenuation of microseismic waves due to the presence of an upward folding of the ocean bottom into the liquid is discussed in this paper. The upward folding of the ocean bottom has been idealized by means of an irregularity in the form of a rectangle intruding into the liquid and the evaluation of the displacement component at any point of the solid medium has been carried out in two stages. First, the change in the incident mode of the surface wave due to the presence of the rectangular irregularity has been determined, and second, the subsequent change of the resulting displacement components due to the termination of the liquid layer and the step change in elevation of the solid medium at the continental margin has been discovered. Finally, numerical calculation has been made to determine the attenuation of the microseismic waves of different periods due to the presence of the rectangular irregularity at the ocean bottom.

抄録全体を表示

Nine isoquinoline alkaloids belonging to the protoberberine, proaporphine and bisbenzyl-isoquinoline series were isolated from Caryomene olivascens (Menispermaceae). Four compounds are new : (-)--norlimacine (4), (-)-caryolivine (), (+)-1, -dehydro--norlimacusine () and N-formylstepharine (3). The last one is the first N-formyl derivative to be reported in the proaporphine group. Its biogenetic origin is discussed. Structures were established on the basis of 360 MHz (FT) nuclear magnetic resonance measurements and also by chemical correlation in the case of 3.

抄録全体を表示

放牧牛において,prostaglandin ()とestradiol benzoate()の同時筋肉注射による発情同期化効果及び同期化された発情期における受胎性にっいて検討し,次の成績を得た。
1.放牧牛31頭(ホルスタイン種未経産牛)において,黄体期にを筋肉注射(A群15頭)あるいはこれと同時に.mgを筋肉注射(群16頭)した結果,処置後31~96時間に発情が発現したものはA群では13頭(.%),群では15頭(93.%)であり,両群の間には大差がなかった。しかし,発情はA群では処置後37~84時間に13頭 (.%),群では31~60時間に14頭(87.%)に集中して発現し,の併用によって発情発現までの時間は短縮した。
.排卵は,A群では処置後73~120時間に13頭(.%),群では61~96時間に14頭(87.%)に起こり,の併用によって排卵の時期は処置後早期に,かつ短い時間帯に集中した。
3.同期化された発情期に授精したA群の13頭中頭(53.%),群の16頭中頭(56.3%)がそれぞれ受胎し,受胎率において両群の間に差異はなかった。
4.以上の成績から,とを同時に併用筋肉注射することは,発情及び排卵の同期化に効果的であることを認めたが,この処置によって同期化された発情期の受胎性については,さらに多数例について検討する必要がある。

抄録全体を表示

The phase diagrams of the Ni-Mo- and Ni-W- ternary systems in the region of less than 50mol% were constructed by thermodynamic calculation, based on the data obtained by thermodynamic measurement of the related materials. We found three ternary eutectic points and three or two ternary peritecto-eutectic points as follows:
:L (1365K, 71.mol%Ni-.0mol%Mo-.mol%)=(Ni)++
:L (1355K, 62.mol%Ni-.mol%Mo-30.mol%)=++
:L (1445K, 42.0mol%Ni-30.mol%Mo-10.3mol%)=(Ni)+NiMo+
P₁:L (1812K, 34.mol%Ni-42.3mol%Mo-.mol%)+MoB=+
:L (1633K, 42.3mol%Ni-40.4mol%Mo-17.3mol%)+Mo=+
P₃:L (1812K, 53.mol%Ni-33.mol%Mo-12.mol%)+Mo=NiMo+
:L (1622K, 51.0mol%Ni-31.mol%W-17.4mol%)=(Ni)+W+
:L (1260K, 71.0mol%Ni-.0mol%W-.0mol%)=(Ni)++
:L (1291K, 65.4mol%Ni-4.mol%W-29.mol%)=++
P₁:L (2115K, 23.mol%Ni-43.1mol%W-33.1mol%)+WB=+
:L (1657K, 48.mol%Ni-33.1mol%W-18.0mol%)+=W+
The calculated phase diagrams are expected to be useful for the development of new Ni-based heat-, corrosion- or wear-resistance alloys.

抄録全体を表示

In this paper, we compare the results of early surgery with those of delayed surgery and discuss the indication of early surgery in 146 cases with ruptured vertebro-basilar aneurysms.
Depending on age, 146 cases were classified into groups: 116 cases under 64 years old (Y-group) and 30 cases over 65 years old (-group).
Timing of operation (within 3 days after SAH: A, 4- days: , over days: ) and clinical grades by Hunt and Kosnik's classification without attendant were as follows: In Y-group, I-II 17, III , IV , V 1 in A, I-II , III 4 in , I-II 60, III , IV in . In -group, I-II 4, , IV 3 in A, III 4, IV 1 in , I-II 10, III , IV 4 in .
Timing of the operation did not differ between the Y-group and -group, but the number of cases classified into HI and IV was significantly larger in the -group than in the Y-group.
Favorable results were obtained as follows : In the Y-group, I-II 15/17 (88%), III / (89%), IV / (40%), V 0/1 in A, I-II / (100%), III 4/4 (100%) in , I-II 54/60 (%), III / (56%), IV 1/ (50%) in . In the -group, I-II /4 (50%), III 0/, IV /3 (66%) in A, III 0/4, IV 0/1 in , I-II /10 (%), III 1/ (50%), IV 0/4 in .
As a whole, surgical results were better in the Y-group than in the -group.
Unfavorable outcomes due to surgical procedure in Grade I-II cases and primary brain damage in Grade III-IV cases were significantly frequent in the -group (3/14: 21%, /16: 56%) than in the Y-group (3/: 3%, /30: 20%).
In the Y-group, outcomes of Grade I-II cases and N cases were not significantly different in the timing of the operation, and the outcome of Grade III cases was better in cases operated on within days after SAH than in cases operated on over days after SAH.
In the -group, the outcome of Grade I-II cases was almost the same irrespective of the timing of the operation except cases over 70 years old with high positioned basilar bifurcation aneurysm.
Two out of 3 favorable cases of Grade III and IV were operated on within 3 days after SAH and those cases showed disturbance of consciousness due to acute hydrocephalus.
From these results and the results of the literature, which has shown a high incidence of deterioration during waiting for the operation in cases with ruptured vertebro-basilar aneurysms, it can be concluded that surgery must be performed as early as possible after SAH in all Grade I-II cases except cases over 70 years old with high positioned basilar aneurysms, and III and IV cases under 64 years old with ruptured vertebro-basilar aneurysms.
Early surgery is also indicated in Grade III and IV cases over 65 years old with disturbance of consciousness due to acute hydrocephalus.

抄録全体を表示

Since 135 years .H.Will Hamburg is one of the leading manufacturers of converting machinery for the paper industry.The company has gained worldwide acknowledgement when introducing cut size sheeters for copy paper. These machines are used worldwide by all well-known paper makers and also in the meantime by smaller paper converting companies.
With regard to folio size sheeter .H.Will was and is reknown for special solutions instead. Based on and with the knowhow of hundreds of cut size sheeters and some hundred folio size sheeters having been delivered, the concept of the Will “global folio size sheeter” type GFS has been developed.
The great technical experience in cutting and transporting paper as well as introducing innovative ideas, new materials and, last but not least, the influence of various customers' requests, which are known to .H.Will from numerous special projects, were the base for development of the GFS folio sheeter.

抄録全体を表示