詳細検索結果
以下の条件での結果を表示する: 検索条件を変更
クエリ検索: %22%E5%92%BD%E9%A0%AD%E5%8C%96%22
4,960,945件中 1-20の結果を表示しています
  • Cbesseredes HORTS
    Journal of Human Ergology
    1982年 11 巻 Supplement 号 429-440
    発行日: 1982/12/15
    公開日: 2011/02/23
    ジャーナル フリー
  • 末次 康将
    マリンエンジニアリング
    2021年 56 巻 5 号 680-687
    発行日: 2021/09/01
    公開日: 2021/10/12
    ジャーナル フリー
  • Suguru TAKATSUTO, Kiyomi KOBAYASHI, Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE
    Agricultural and Biological Chemistry
    1988年 52 巻 12 号 3217-3218
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • Yasuhiro SUGIMOTO, Kazuma SAKATOH
    IEICE Transactions on Electronics
    2013年 E96.C 巻 6 号 867-874
    発行日: 2013/06/01
    公開日: 2013/06/01
    ジャーナル 認証あり
    Circuit techniques to enhance the linearity of input-voltage-to-current (V/I) conversion and to increase the output impedance of a current source by compensating for the low intrinsic gain of a transistor were introduced to realize a high-frequency operational transconductance amplifier (OTA) for a low supply voltage using sub-100-nm CMOS processes. Applying these techniques, a MOS 7th-order Gm-
    C
    linear-phase low-pass filter (LPF) was realized using a 65nm CMOS process. A simplified biquad LPF that can serve as a component of a 7th-order LPF was newly developed by replacing OTAs with resistors. As a result, the -3dB frequency bandwidth, group delay ripple, 3rd-order distortion, and 3rd-order input intercept point (IIP3) were 200MHz, 2.2%, ≤ -55dB with a 100MHz input, and +10.3dBm, respectively, all with a ±
    0
    .1Vp-p input signal at each input terminal in the pseudodifferential configuration. The LPF including an output buffer dissipated 60mW in the case of a 1.2V supply. Wide spurious-free dynamic range (SFDR) characteristics were confirmed up to high frequencies.
  • Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE, Kiyomi KOBAYASHI, Suguru TAKATSUTO
    Agricultural and Biological Chemistry
    1988年 52 巻 8 号 2117-2118
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • Thomas J. Albin
    人間工学
    1999年 35 巻 1Supplement 号 31
    発行日: 1999/05/01
    公開日: 2010/03/12
    ジャーナル フリー
  • Paulo F Silveira, Patricia L Alves, Rafaela F Alponti
    日本薬理学会年会要旨集
    2018年 WCP2018 巻 WCP2018_PO3-6-14
    発行日: 2018年
    公開日: 2020/09/10
    会議録・要旨集 オープンアクセス

    Background: Exenatide (EXE), a prototypical GLP-1R agonist, is known as glucoregulator, antiobesogenic and antidyslipidemic in hyperlipidic and hyperglucidic diet-induced obesity in rats (DIO). Objective: To evaluate bone effects of DIO and DIO treatment with EXE (DIO-

    E
    ). Methods: 72-75-day-old male rats had access only to (i) hyperlipidic food (
    5
    .2 kcal/g) and 30% sucrose solution for drinking (1.2 kcal/mL), or (ii) received normocaloric diet (3 kcal/g) and were allowed to feed and to drink water
    ad
    libitum
    . 122-125-day-old rats with 20% overweight were selected from i as obese and those with normal weight were selected from ii as control (
    C
    ) animals. Thus, obese animals remained untreated (DIO) or were treated with 10 μg EXE/kg sc (DIO-
    E
    ) daily, for 20 days. Plasma levels of insulin (INS), leptin (LEP), osteocalcin (OCN), carboxy-terminal telopeptide of type 1 collagen (CTX-1) (ng/mL), as well as calcitonin (CT) and procollagen type 1 amino-terminal propeptide (P1NP) (pg/mL) were measured by ELISA. Bone mineral density of femur (BMDF) (g/cm3) was measured by X-rays. Results: DIO exhibited similar INS (12.
    9
    ±1.83, n=4) and CT (2.80±1.05, n=4), higher LEP (
    0
    .33±
    0
    .04, n=
    5
    ) and lower CTX-1 (
    0
    .48±
    0
    .
    22
    , n=3) than
    C
    . The treatment of DIO with EXE restored LEP (
    0
    .04±
    0
    .02, n=
    5
    ), decreased CTX-1 (
    0
    .50±
    0
    .
    22
    , n=
    5
    ) and increased CT (6.87±
    0
    .72, n=
    5
    ). The levels of OCN (1.58±
    0
    .41, n=
    5
    ), P1NP (
    92
    .64±16.89, n=
    5
    ) and BMDF (1.
    9
    ±
    0
    .07, n=
    5
    ) of
    C
    and those of DIO and DIO-
    E
    were similar. Conclusions: Despite of increased LEP, decreased CTX-1 and normal OCN, P1NP and BMDF reflect a relative normal balance in bone turnover in DIO. Mechanical overloading due to high body mass is known as a factor that promotes this normal condition. Given that EXE decreases 14% body mass of DIO, the present study suggests that normalization of LEP and increased CT and decreased CTX-1 are concomitant beneficial effects of EXE that contribute for maintaining bone turnover under decreased mechanical load in DIO.

    Supported by FAPESP, CNPq and CAPES

  • Kazuo TAKEUCHI, Masayuki ATSUCHI, Shoji ODA, Minoru JINBO, Takeshi MASUI, Motohide OGASHIWA
    Neurologia medico-chirurgica
    1968年 10 巻 132-133
    発行日: 1968年
    公開日: 2007/08/17
    ジャーナル フリー
  • S. SICSIC, J. F. LE BIGOT,
    C
    . VINCENT,
    C
    . CERCEAU, F. LE GOFFIC
    The Journal of Antibiotics
    1982年 35 巻 5 号 574-579
    発行日: 1982年
    公開日: 2006/04/12
    ジャーナル フリー
    The activities of tobramycin derivatives acetylated and ethylated on the 6'-N, 2'-N and 3-N positions were examined. The MICs of these derivatives against tobramycin sensitive strains indicated that 2'-N-ethylated and 6'-N-ethylated derivatives have a fairly good activity, and confirmed that the 3-N position is the most important one for antibiotic activity since 3-N derivatives were less active. The MICs of these derivatives against tobramycin resistant strains, and their inactivation by tobramycin modifying enzymes were examined. These results showed that 2'-N or 6'-N ethylation protects the drug against inactivation by AAC(2') or AAC(6'), respectively, and 2'-N-ethyltobramycin and 6'-N-ethyltobramycin were active against strains containing these modifying enzymes. On the other hand, 3-N ethylation protects the drug against inactivation by AAC(3) but 3-N-ethyl tobramycin does not inhibit strains containing this enzyme.
  • /, 龍岡 文夫, FUMIO TATSUOKA
    地盤工学会論文報告集
    1997年 37 巻 4 号 121-126
    発行日: 1997/12/15
    公開日: 2008/02/29
    ジャーナル フリー
    The design implication of stress-confinement effect of nonwoven geotextile is addressed. The unconfined and confined strengths of a selected needle-punched nonwoven geotextile are used to conduct a comparative design of a granular soil retaining wall based on a limit equilibrium approach. A higher wall may be allowed when considering the confined strength as compared to the unconfined strength. For a selected wall height, confined strength allows for fewer geotextile layers when compared to that designed using unconfined strength. It is recommended that stress-confinement test procedure should be standardized so that confinement effect of some nonwoven geotextiles may be incorporated into an individual wall design procedure.
  • 西村 真一, 清水 英良, / 仲野 良紀, RYOKI NAKANO
    地盤工学会論文報告集
    1998年 38 巻 3 号 89-95
    発行日: 1998/09/15
    公開日: 2008/02/29
    ジャーナル フリー
    Leakage of water due to internal erosion through a dam body or foundation is a major problem with fill-type dams. Recent case histories and research suggest that most cases of internal erosion are possibly triggered by hydraulic fracturing. However, the quantitative mechanism of hydraulic fracturing still remains to be solved. Therefore in-situ hydraulic fracture tests were carried out with a cheap, concise apparatus using boreholes dug in the soft clayey volcanic soil foundation of a low earth dam (Oyachi Dam) in Niigata Prefecture. Water was injected into the foundation through a perforated pipe by two methods : one was under a controlled injection pressure and the other was a controlled injection flow rate. In the former method, the relationship between flow rate and injection pressure was observed and it was found that a yield pressure or fracture pressure existed in all the tests. By repeating the injection test it was confirmed that once a crack is developed, it is very easily reopened by a water pressure a little higher than the earth pressure exerted on the crack. In the latter method, the relationship between injection pressure and time was observed and it was found that fracture pressure varied with flow rate. The boreholes were excavated to observe the development of fracture cracks and it was also found that the cracks had developed perpendicular to the borehole periphery, which means that fracture cracks were induced by tensile stress and denies the explanation that fractures are caused by shear failure.
  • その所属腱索および乳頭筋について
    島田 博
    日本医科大学雑誌
    1981年 48 巻 6 号 779-789
    発行日: 1981/12/15
    公開日: 2010/10/14
    ジャーナル フリー
    Although there have been numerous articles concerning the anatomy of the atrioventricular valve in man, only a few publications have recorded the relationship between the chordae tendineae and the papillary muscles. The purpose of this paper is to study the relationship among the shape and size of the atrioventricular valve, the chordae tendineae and the papillary muscles. 50 subjects, as listed in Table 1, were analyzed by the Taniya-Hashimoto Method.
    The results obtained were as follows:
    1) The right atrioventricular valve was classified into two types: 33 cases (66%) of three irregularly shaped cusps, i.
    e
    . type I, and 17 cases (34%) of four or five cusps, i.
    e
    . type II.
    2) The average circumference of the right atrioventricular orifice (ostium atrioventriculare dextrum) was 11.
    96
    cm (
    9
    .63.15.06cm) in type I and 12.19cm (
    9
    .52.15.
    22
    cm) in type H. There existed no significant difference in the circumference of the atrioventricular orifice between type I and II.
    3) The average length of the cusp-fundus (the length of the fixed margin of the cusp) was as follows:
    type I: anterior cusp…………4.13cm (2.03-6.
    96
    cm)
    posterior cusp…………3.62cm (1.21-
    5
    .44cm)
    septalcusp……………4.21cm (3.11-6.08cm)
    type II: anterior cusp…………4.10cm (2.68-
    5
    .42cm)
    posterior cusp…………3.67cm (
    0
    .94-
    5
    .70cm)
    septal cusp……………4.43cm (2.
    96
    -6.53cm)
    4) The average width of the cusp (the maximum distance between the apex and the fundus of the cusp) was as follows:
    type I: anterior cusp…………1.86cm (1.26-2.29cm)
    posterior cusp…………1.62cm (
    0
    .62-2.94cm)
    septal cusp……………1.76cm (1.15-2.72 cm)
    type II: anterior cusp…………1.
    92
    cm (1.40-2.34cm)
    posterior cusp…………1.72cm (
    0
    .94-2.42cm)
    septal cusp……………1.84cm (1.14-2.53cm)
    The length or width of the cusp in type I was similar to that in type II.
    5
    ) The papillary muscles consisted of five groups, which were named the anterior, postlateral, postmedial, postseptal and septal muscles. The average number of the papillary muscles per right ventricle was
    5
    .7 (2.
    0
    .
    9
    .
    0
    ). The chordae tendineae from the anterior papillarymuscles were attached to the anterior and posterior cusps and those from the postlateral and postmedial muscles were attached to the posterior and septal cusps. The chordae tendineae from the postseptal muscles were linked only to the septal cusp and those from the septal muscles were connected to the septal and anterior cusps.
    6) The average number of the stems of the chordae tendineae from the papillary muscles were as follows:
    From the anterior papillary muscles………7.2 (2.
    0
    -14.
    0
    )
    the postlateral papillary muscles……3.
    5
    (1.
    0
    -
    8
    .
    0
    )
    the postmedial papillary muscles……4.
    0
    (1.
    0
    -
    8
    .
    0
    ) the postseptal papillary muscles……4.
    5
    (1.
    0
    -13.
    0
    ) the septal papillary muscles………
    5
    .7 (2.
    0
    -12.
    0
    )
    The average n umber of the stems of the chordae tendineae per right ventricle was 24.4 (16.
    0
    -35.
    0
    ).
    7) The tip of the chordae tendineae are attached to the fixed margin of the valve cusp, i.
    e
    . type A, to the ventricular surface, i.
    e
    . type B and to the free margin, i.
    e
    . type
    C
    . The average number of them were 23.4 (14.
    0
    -32.
    0
    ) in type A, 19.2 (4.
    0
    -37.
    0
    ) in type B and 68.1 (31.
    0
    -105.
    0
    ) in type
    C
    . The average number of the apexes of the chordae tendineae per right ventricle was 110.7 (53.
    0
    -166.
    0
    ).
    8
    ) The average number of the chordae tendineae for the anterior cusp was 34.
    9
    (12.
    0
    -64.
    0
    ), for the posterior cusp 30.
    5
    (
    5
    .
    0
    -65.
    0
    ) and for the septal cusp 45.3 (23.
    0
    -68.
    0
    ).
  • FRANÇOIS LE GOFFIC, MARIE-LOUISE CAPMAU, ERÉDÉRIC TANGY, ELIANE CAMINADE
    The Journal of Antibiotics
    1980年 33 巻 8 号 895-899
    発行日: 1980年
    公開日: 2006/04/12
    ジャーナル フリー
    (3H) Tobramycin was used as a probe to determine the relationship between the structure of aminoglycoside antibiotics and their ability to remove this drug from its higher affinity binding site on the ribosome. The dissacharide moieties (neamine, tobramine, gentamine) appeared to have a common binding site, whereas the kanosamine, garosamine and ribose moieties determined the specificity of this binding. Amikacin and butikacin behaved in an anomalous manner in spite of their close structural relationship to tobramycin.
  • Mohd Suhail, Mohd Faizul Suhail, Hina Khan
    Journal of Clinical Biochemistry and Nutrition
    2008年 43 巻 3 号 210-220
    発行日: 2008年
    公開日: 2008/10/31
    ジャーナル フリー
    We compared three groups of pregnant women: placebo with normotensive women, group A which included preeclamptics, and group B which comprised preeclamptics who were supplemented their diets with vitamins
    C
    and
    E
    . MDA increased from 6.
    22
     ± 2.
    8
    (placebo) to
    8
    .48 ± 1.2 (A) and
    8
    .02 ± 1.
    8
     nmol/gHb (B). NO concentrations were enhanced from 19.3 ± 4.2 (P) to 23.
    8
     ± 6.4 (A) and 24.1 ± 
    5
    .4 μmol/L (B). GSH contents were decreased from 10.42 ± 2.81 (P) to
    8
    .02 ± 2.
    92
    (A) and
    9
    .39 ± 1.02 μmol/g Hb (B), whereas GSSG concentrations increased from
    0
    .98 ± 
    0
    .28 (P) to 1.24 ± 
    0
    .29 (A) and 1.08 ± 
    0
    .12 μmol/g Hb (B). SOD activity decreased 23% in A and 14% in B; GRx decreased 27% in A and
    5
    .
    5
    % in B; GPx decreased 12% in A and
    9
    .6% in B. Catalase activity, however, increased 27% in A and 29% in B as compared to control. Thus, we conclude that the use of vitamins
    C
    and
    E
    should be considered for the control of certain important biochemical indices during the development of preeclampsia; however, further studies are needed to develop methods for the prevention of preeclampsia in women at high risk.
  • CHAIM J. PORAN, KINGSEN HEH, JORGE A. RODRIGUEZ
    土質工学会論文報告集
    1992年 32 巻 4 号 81-92
    発行日: 1992/12/15
    公開日: 2008/02/29
    ジャーナル フリー
    The paper presents results from an extensive experimental model study of response of dry sand to impact of a rigid tamper. In the laboratory tests a circular steel tamper was repeatedly dropped on sand contained in a large tank. Measurements included tamper acceleration aud soil pressure at impact, tamper settlement, aud soil densities and strains. Effects of tamper drop height, weight and contact area were investigated. A method is presented for the evaluation of global dynamic stiffness of the soil mass affected by the impact by calculating a dynamic settlement modulus (DSM). The DSM values are determined from integration of the impact acceleration record with respect to time using measured integration constants. DSM values show good correlation to soil densities and corresponding elastic moduli obtained from laboratory tests for loose sand. However, for dense sand, results indicate apparent discrepancies between elastic modulus and the higher DSM values. Analyses of normalized impact energy and the resulting densification in the sand in terms of normalized dimensions of volumetric strain (relative density) contours show unique correlations which are used for a proposed rational design method for dynamic compaction in dry sandy soils.
  • 榎 明潔, 八木 則男, 矢田部 龍一, 一本 英三郎
    土質工学会論文報告集
    1991年 31 巻 2 号 1-13
    発行日: 1991/06/15
    公開日: 2008/02/29
    ジャーナル フリー
    It has been shown after mathematical and mechanical investigation that Limit Equilibrium Method (LEM) can be considered as a method to obtain the necessary condition of Slip Line Method (SLM), and that the solution can be obtained under the condition that Fs=1 and ∂Fs/∂θ=O, where Fs is the safety factor and θ is the inclination of the plane on which the safety factor is defined. Next, the generalized LEM (GLEM) is proposed, dealing with the following points : (1) Triangular or quadrangular blocks can be treated; (2) Safety factors are defined also on interblock planes; and (3) All types of plastic problems, slope stability, bearing capacity, and earth pressure are identically formulated. Two situations regarding treatment of the moment equilibrium condition are discussed. GLEM is applied to well-known problems. The results agree well with those obtained by theoretical methods. GLEM can be used to obtain the distribution of earth pressure or bearing capacity. GLEM, Iike ordinary LEM, is very effective for the practical problems, but GLEM is more theoretical and it can result in more accurate solutions.
  • 村瀬 稔, 木股 裕子, 仲西 寿男, 小澤 一弘, 赤羽 荘資, 浅川 豊, 南澤 仁志, 上條 茂徳, 小沼 博隆
    日本食品微生物学会雑誌
    2001年 18 巻 3 号 75-81
    発行日: 2001/09/30
    公開日: 2010/07/12
    ジャーナル フリー
    At low levels, enterohemorrhagic Escherichia coli should be selectively isolated by suppressing competing microflora in meat samples. In conventional methods, MacConkey II Agar with
    C
    -T Sorbitol (cefixime-tellurite, CT-SMAC) which utilizes the ability of
    E
    . coli
    O157 to ferment sorbitol, and media containing
    E.coli
    -specific chromogenic substrates, are used for detecting
    E
    . coli
    O157.
    In this study, we compared two types of
    BD
    CHROMagarTM O157 for the isolation of enterohemorrhagic
    E
    . coli
    O157 (improved
    BD
    CHROMagarTM O157 and conventional
    BD
    CHROMagarTM O157) with CT-SMAC by using the Miles-Misra method and evaluating the recovers from ground beef and human fecal samples. The results obtained are described below:
    1. In the inoculation test with three media by the Miles-Misra method, improved
    BD
    CHROMagarTM O157 inhibited the growth of all organisms except
    E
    . coli
    O157 better than the two other media and allowed easy differentiation from
    E
    . hermannii
    , which could not be distinguished on CT-SMAC.
    2. In the
    E
    . coli
    O157 detection test for ground beef artificially inoculated with
    E
    . coli
    O157 at 1 cfu/g, the detection rate of improved
    BD
    CHROMagar TM O157 was 95%, CTSMAC 75% and conventional
    BD
    CHROMagarTM O157 40%, respectively.
    4. In the
    E
    . coli
    O157 detection test for
    E
    . coli
    O157 positive human fecal samples, the detection rate of improved
    BD
    CHROMagarTM O157 was 54.
    5
    %, CT-SMAC 50% and conventional
    BD
    CHROMagarTM O157
    22
    .7%, respectively.
  • / 鵜飼 恵三, KEIZO UGAI
    地盤工学会論文報告集
    1998年 38 巻 3 号 201-207
    発行日: 1998/09/15
    公開日: 2008/02/29
    ジャーナル フリー
    A comparative study of the static and dynamic response of a slope is carried out, using the large deformation theory of the updated Lagrangian formulation and the conventional infinitesimal theory. In the static analysis, a strength reduction method proposed by one of the authors is used to evaluate the safety factor of the slope. It is found that by the large deformation theory, the safety factor is larger than that calculated by the infinitesimal theory, and this difference becomes large along with the reduction of elastic modulus. In the dynamic analysis, it is observed that the large deformation theory gives smaller sliding displacement and larger response acceleration than the infinitesimal approach. It is concluded that in many cases the large deformation approach gives more adequate solutions.
  • 関節円板の前方転位の程度と復位および臨床所見との関係
    松木 宏真, 尾崎 登喜雄
    日本口腔外科学会雑誌
    1999年 45 巻 4 号 241-251
    発行日: 1999/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    To determine the position of the anteriorly displaced articular disc, we examined temporomandibular joints by magnetic resonance imaging (MRI) in 54 patients with unilateral temporomandibular joint dysfunction. MRI was done before conservative therapy in the occlusal and maximal open-mouth position. We drew a straight line connecting the lowest point of the articular eminence (point A) and the highest point of the external acoustic pore (point
    E
    ) by tracing the sagittal view on MRI. On the standard A-
    E
    line, points B',
    C
    ', and D' were sought by dropping perpendicular lines from the deepest point of the glenoid fossa (point B), the highest point of the condylar head (point
    C
    ), and the most posterior point of the articular disc (point D). We then determined the sagittal position of the articular disc in the glenoid fossa by measuring the distances
    AD
    ' and
    C
    'D' and sought the correlation between these distances and clinical findings. The results were as follows. 1. The distance
    AD
    ' in 33 patients with MRI-defined irreversible displacement of the disc was shorter than that in 10 patients with reversible displacement (3.7±1.
    9
    mm vs 6.
    8
    ±2.
    0
    mm, p<
    0
    .0001). In contrast, the distance
    C
    'D' in the former was longer than that in the latter (6.
    0
    ±1.7mm vs 3.4±1.
    5
    mm, P<
    0
    .0001). Of 29 discs displaced anteriorly less than
    5
    mm in distance
    C
    'D', 19 (66%) had reversible or no displacement. However, 23 (
    92
    %) of 25 discs displaced more than
    5
    mm in distance
    C
    'D' had irreversible displacement. 2. Disc deformity and abnormal signal intensity bands in the condylar head closely correlated with distances
    AD
    ' and
    C
    'D'. In 17 patients without disc deformity, mean
    AD
    ' and
    C
    'D' distances were
    9
    .
    8
    ± 2.7mm and
    0
    .2± 2.
    8
    mm, respectively. In 19 and 18 patients with mild to moderate and severe deformity, the mean
    AD
    '(
    C
    'D') distances were
    5
    .4±1.
    8
    mm (4.
    5
    ±1.6mm) and 2.7±1.
    8
    mm (6.
    8
    ±1.
    5
    mm), respectively. 3. Although distance
    AD
    ' and
    C
    'D' did not correlate with clinical symptoms, the degree of anterior disc displacement correlated with the therapeutic effect of conservative therapy. The mean
    AD
    ' distance (7.3±3.7mm) in 15 patients with a complete response to conservative therapy was longer than that (3.4±1.4mm) in
    5
    patients with no improvement. These results indicate that the sagittal position of the articular disc can be determined by MRI and that successful conservative therapy is unlikely if anterior disc displacement extends beyond
    5
    mm from the top of the condylar head, often resulting in irreversible displacement.
  • J. Bros
    Publications of the Research Institute for Mathematical Sciences
    1977年 12 巻 Supplement 号 19-37
    発行日: 1977年
    公開日: 2009/06/17
    ジャーナル フリー
feedback
Top