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  • Grover Loening
    日本航空学会誌
    1963年 11 巻 119 号 373-380
    発行日: 1963年
    公開日: 2009/05/25
    ジャーナル フリー
  • Joey
    B
    . Tanney, Leonard J. Hutchison
    Mycoscience
    2012年 53 巻 1 号 31-35
    発行日: 2012年
    公開日: 2023/03/31
    ジャーナル オープンアクセス

    The ability of Climacodon septentrionalis to immobilize and kill a mycophagous nematode (Aphelenchoides sp.) in vitro is described for the first time. Two isolates produced droplets (20–45 μm in diameter) that formed at the apices of tall, stalked, and branching secretory cells (700–

    1
    ,500 μm tall). On 2% modified malt extract agar, nematodes became enveloped in the droplets, which restricted their ability to move and resulted in complete immobilization and death within several hours of contact. The rate of decomposition of the nematodes varied considerably, with most individuals persisting for weeks whereas others were degraded within several days and appeared to be colonized by dense hyphal growth. This study provides the first documentation of a non-agaricoid fungus producing secretory cells that are able to immobilize nematodes.

  • 小田切 孝人, 田代 眞人
    ウイルス
    2013年 63 巻 2 号 233-240
    発行日: 2013/12/25
    公開日: 2014/10/31
    ジャーナル フリー
  • George W. Lee
    燃料協会誌
    1973年 52 巻 3 号 171-177
    発行日: 1973/03/20
    公開日: 2010/06/28
    ジャーナル フリー
  • 佐藤 敬之輔
    デザイン学研究
    1970年 1970 巻 11 号 45-55
    発行日: 1970/03/30
    公開日: 2017/07/25
    ジャーナル フリー
    [
    1
    ] The purpose of this reserch is to make clear what type of design can give good effects to win the high readership score. At the begining I had to know what factors decide the readership score, and how to change the quality of the desing into numerical value. I have used the method of multi-dimentional analysis with the help of a computer, and got the estimation formula, with
    7
    kinds of factors, as follows ; A^^〜=
    B
    +C+D+K+
    aE
    +bF+cG. A^^〜=estimated values of the readership score.
    1
    )
    B
    , C, D, K : these four factors are given as category values (so we call them); each factor is classified into several categories.
    B
    =week day, classified into
    7
    categories. C=pages of a newspaper, which are characterized by the kinds of articles, news, and the other reading matters, classified into
    22
    categories. D=kinds of goods and trades of the advertizement, classified into 14 catedories. K=constants, given to each 13 surveys. 2)
    E
    ,
    F
    , G : these factors are given as numerical values. G=area of advertizement, measured by the unit of column in the whole page length, being classified into
    6
    kinds of area (2.
    5
    , 3.
    5
    ,
    5
    ,
    7
    , 10, 15) and 15 column means a whole page, about 2,000cm^2.
    E
    ,
    F
    are the marks obtained in the design of advertizements.
    E
    =sum of the marks obtained in each design element on the advertizement.
    F
    =the marks obtained on the whole effect of the design. 3) a,
    b
    , c : coefficients Using the above formula with the category values and the coefficients, we can obtain the naked design effect from the actual value A of readership score:
    aE
    +bF=A-(
    B
    +C+D+K+cG). In this research, I used
    1
    ,829 data of readership score from 1960 to 1968, being obtained by 13 survevs, spring and autumn twice a year. The sample of size each survey was 3,541, 2,251, or 200 in the other 11 surveys. Multiple correlation coefficient between the estimated value A^^〜 and the actual value A is 0.951. The table 2^* shows the contribution indexes of each factor by 3 kinds of expression-(
    1
    ) Range : the absolute difference between the maximum and the minimum category values, (2) Standard deviations of the category values, (3) Partial correlation coefficient : the relationship between the actual values A and each factors. *see the table 2 in the thesis in Japanese. [2] The important point was in the determination of the values of
    E
    ,
    F
    .
    E
    is the sum of the marks obtained in each design element, classified into four kinds :
    E
    =
    E
    _
    1
    +
    E
    _2+
    E
    _3+
    E
    _
    4
    . design elements [table]
    E
    _
    1
    ,
    E
    _2,
    E
    _3,
    E
    _
    4
    , these values have the
    5
    grades, as 0,
    1
    , 2, 3,
    4
    and 0 is given to the design that has no attractive effect or no applicable element. And
    E
    obtain the marks of 0 to
    9
    grades as the sum of them. The values of
    F
    have also
    5
    grades, 0 to
    4
    . The principles to determine the values of
    E
    ,
    F
    are as follows : a) The marks obtained of
    E
    ,
    F
    must be the relative values among the each survey, and at the same time, they must have constancy within the same survey-the same elements of design must win the same marks obtained.
    b
    ) They must be determined as to win the highest multiple correlation coefficient, when they are put into the estimation formula. c) They must be reasonable. In order to justify them, we must carry many researches on the actual condition. The frequency of accurence of each grade of
    E
    ,
    F
    values, as the table
    5
    -
    4
    , and
    5
    -
    5
    in the thesis in Japanese.
  • Suguru TAKATSUTO, Kiyomi KOBAYASHI, Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE
    Agricultural and Biological Chemistry
    1988年 52 巻 12 号 3217-3218
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • I.
    F
    . Davies
    Journal of Light & Visual Environment
    1984年 8 巻 1 号 1_9-1_20
    発行日: 1984年
    公開日: 2011/05/20
    ジャーナル フリー
  • M. L. GHOSH
    Journal of Physics of the Earth
    1972年 20 巻 2 号 165-186
    発行日: 1972年
    公開日: 2009/04/30
    ジャーナル フリー
    The possibility of attenuation of microseismic waves due to the presence of an upward folding of the ocean bottom into the liquid is discussed in this paper. The upward folding of the ocean bottom has been idealized by means of an irregularity in the form of a rectangle intruding into the liquid and the evaluation of the displacement component at any point of the solid medium has been carried out in two stages. First, the change in the incident mode of the surface wave due to the presence of the rectangular irregularity has been determined, and second, the subsequent change of the resulting displacement components due to the termination of the liquid layer and the step change in elevation of the solid medium at the continental margin has been discovered. Finally, numerical calculation has been made to determine the attenuation of the microseismic waves of different periods due to the presence of the rectangular irregularity at the ocean bottom.
  • Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE, Kiyomi KOBAYASHI, Suguru TAKATSUTO
    Agricultural and Biological Chemistry
    1988年 52 巻 8 号 2117-2118
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • Yukichi Yamaguchi, Jian-zhi Runan(Gen), Teruaki Nagahara
    Journal of the Physical Society of Japan
    1975年 38 巻 4 号 911-916
    発行日: 1975/04/15
    公開日: 2007/06/01
    ジャーナル 認証あり
    The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the 116mIn activity. Directional correlations are also measured for 818–1293 and 1097–1293 keV cascades. The M
    1
    -
    E
    2 mixing ratio δ, and the
    E
    0-
    E
    2 mixing ratio μk are obtained for 818.
    7
    keV
    22
    +→21+ transition to be δ=
    1.52
    0.22
    +0.26, and μk
    6
    .
    1
    ×10
    4
    respectively. The
    E
    2 branching ratio
    B
    (
    E
    2;
    22
    +
    →0g+):
    B
    (
    E
    2;
    22
    +→21+):
    B
    (
    E
    2;
    22
    +→01+) is determined to be 0.0158:
    1
    .0:
    5
    .86.
  • Keishi Hata, Fuyuki Sugawara, Naganori Ohisa, Saori Takahashi, Kazuyuki Hori
    Biological and Pharmaceutical Bulletin
    2002年 25 巻 8 号 1040-1044
    発行日: 2002年
    公開日: 2002/08/01
    ジャーナル フリー
    We screened the differentiation-inducing activities of 39 mushroom extracts from Akita prefecture, Japan, on the mouse osteoblastic cell line, MC3T3-
    E
    1
    . Sixteen phosphate buffered saline (PBS), 8 boiled PBS, 14 ethanol and 12 methanol extracts induced alkaline phosphatase (ALP) activities, an indicator of MC3T3-
    E
    1
    cell differentiation. The enzyme activities were markedly induced by extracts of Tricholoma auratum, and we isolated the active compound from methanol extracts of this mushroom. Physical data for the isolated active compound were identical to those for (
    22E
    ,24R)-ergosta-
    7
    ,
    22
    -diene-3β,
    ,
    -triol (
    1
    ).
    1
    induced ALP activities of MC3T3-
    E
    1
    cells and promoted cell proliferation. To investigate the relationships between the chemical structure and differentiation-inducing activity of the compound, ALP-inducing activities of MC3T3-
    E
    1
    cells by
    1
    , ergosterol (2), ergocalciferol (3), cholesta-3β,
    ,
    -triol (
    4
    ),
    7
    -dehydrocholesterol (
    5
    ) and cholecalciferol (
    6
    ) were tested. The enzyme activities of MC3T3-
    E
    1
    cells were increased 3.0-fold by 10 μM
    1
    and 2.
    4
    -fold by 10 μM
    4
    . However, 2, 3,
    5
    and
    6
    did not induce MC3T3-
    E
    1
    cell ALP activity at 0.
    1
    —10 μM. These results suggested that the OH groups at C-
    5
    and/or C-
    6
    of
    1
    and
    4
    played an important role in their differentiation-inducing activities on MC3T3-
    E
    1
    cells. Furthermore,
    1
    suppressed induction of MC3T3-
    E
    1
    cell apoptosis by serum starvation.
  • 吉井 一郎
    日本臨床整形外科学会雑誌
    2017年 43 巻 1 号 1-9
    発行日: 2017年
    公開日: 2018/04/05
    ジャーナル 認証あり

    背景と目的:ステロイド性骨粗鬆症は,積極的な治療介入が必要とされる.その第一選択薬はビスホスホネート製剤(以下ビス)であるが,近年,デノスマブ(以下デノス)も注目を浴びている.ステロイド性骨粗鬆症の骨密度に対する両者の効果を比較検討した.

    方法:ステロイド性骨粗鬆症の管理と治療ガイドライン:2014年改訂版の薬物療法開始の基準を満たした患者を対象とした.無治療群(N群)と,治療介入群として当初よりビスで治療したBB群,ビス後デノスに変更したBD群,デノスで治療したDD群,デノス後ビスに変更したDB群を抽出し,ステロイド投与を開始した時,ステロイド性骨粗鬆症に対する治療を開始した時または薬剤変更から

    6
    カ月後の腰椎,大腿骨頚部と大転子部の骨密度を測定し,それらの変化を統計学的に比較検討した.

    結果:149例が抽出され,その内訳は,N群48例,BB群24例,BD群

    22
    例,DD群21例,DB群34例であった.治療開始時または薬剤変更から
    6
    カ月後にBD群を除くすべての治療介入群で腰椎の骨密度が上昇した.大腿骨の骨密度は,BD群において薬剤変更後に上昇に転じた.

    考察:デノスにはビスと同様の骨密度上昇効果があると考えられた.

    結論:デノスは,ステロイド性骨粗鬆症治療の第一選択薬となり得る.

  • 増大する資源
    E
    .
    F
    . Boswell
    紙パ技協誌
    1998年 52 巻 7 号 885-889
    発行日: 1998/07/01
    公開日: 2009/11/19
    ジャーナル フリー
    The world is in the midst of a huge fundamental shift in fibre supply, demand balances, and policy changes. Governments around the world are introducing policy changes which influence the supply demand balance as the politicians' thoughts are uttered. Government agencies and their bureaucrats are imposing changes on industry even before the legislation is passed by the government in question.
    This ad hoc change process will continue for a time to come until the countries in question show a tough-mindedness with regard to their land use policies. Policies affecting forest areas such as protection areas, Native land claims, the protection of biodiversity and a true goal of sustainable development ; which addresses the combined issues of cultural, environmental, social and economic matters.
    Eventually all of these difficult issues will reach essential closure. Then there will be great new opportunities for investment to meet the growing demand for forest products ; leading to a strengthening competitive position in the more traditional producing areas such as Canada.
  • 鍛治 健司, 葛谷 昌之 /, RAYMONDN. CASTLE
    Chemical and Pharmaceutical Bulletin
    1970年 18 巻 1 号 147-156
    発行日: 1970/01/25
    公開日: 2008/03/31
    ジャーナル フリー
    2-Benzyl-
    4
    -chloro-
    5
    -mercapto-3 (2H)-pyridazinone (
    1
    ) was heated in ethanol under reflux for 10 hours to form concurrently 2,
    7
    -dibenzyldipyridazo [
    4
    ,
    5
    -
    b
    :
    4
    ',
    5
    '-
    e
    ]-
    1
    ,
    4
    -dithiin-
    1
    ,
    6
    (2H,
    7
    H)-dione (Ia) (57% in yield) and 2, 8-dibenzyldipyridazo [
    4
    ,
    5
    -
    b
    :
    4
    ',
    5
    '-
    e
    ]-
    1
    ,
    4
    -dithiin-
    1
    ,
    9
    (2H, 8H)-dione (IIa) (14% in yield). Assignment of the two products to the corresponding structures is established by their physico-chemical constants and chemical behaviors. The concurrent formation of the dipyridazo [
    4
    ,
    5
    -
    b
    :
    4
    ',
    5
    '-
    e
    ]-
    1
    ,
    4
    -dithiin-
    1
    ,
    6
    (2H,
    7
    H)-dione and the -
    1
    ,
    9
    (2H, 8H)-dione were observed in, not only heating
    4
    -chloro-
    5
    -mercapto-3 (2H)-pyridazinones (
    1
    -3) in polar solvent, but warming
    4
    -mercapto-
    5
    -chloro-3 (2H)-pyridazinones (
    4
    -
    6
    ) in the presence of potassium carbonate in DMF. For the interpretation of the reaction, keto-thioketo carbenes as active intermediate species and a reversible interconversion among them are suggested on the basis of the fact that there was nonexistence of an equilibrium between the two compounds, such as Ia and IIa, under the reaction condition and a trapping keto-thioketo carbene species as 2-phenylimino-
    5
    -benzylpyridazo [
    4
    ,
    5
    -d]-
    1
    , 3-dithiol-
    4
    (
    5
    H)-one (IVa) (14% in yield) along with the major products, (Ia) and (IIa), was furnished by warming
    1
    with phenylisothiocyanate in the presence of triethylamine in dry benzene. On the contrary, participation of a reversible interconversion between Ia and IIa, to a considerable extent, with the concurrent formation of them in the case of benzylation of either Ib or IIb, by warming with benzylchloride in the presence of potassium carbonate in DMF at 80°, might not be neglected, because an attempted approach to an equilibrium between Ia and IIa in a similar reaction condition except the use of benzylchloride realized, whereas non-existence of an equilibrium between Ib and IIb in the similar reaction condition was observed.
  • Özkan ASLANTAŞ, Ebru Şebnem YILMAZ
    Journal of Veterinary Medical Science
    2017年 79 巻 6 号 1024-1030
    発行日: 2017年
    公開日: 2017/06/16
    [早期公開] 公開日: 2017/04/27
    ジャーナル フリー

    This study aimed to determine the prevalence of fecal carriage of extended spectrum β-lactamase (ESBL) and/or plasmidic AmpC β-lactamase (pAmpC) producing Escherichia coli among dogs (n=428) in Turkey. Polymerase chain reaction (PCR) and sequencing were used to characterize genes encoding β-lactamase and plasmid mediated quinolone resistance (PMQR). Antimicrobial susceptibility testing and PCRs for virulence genes and phylogenetic groups were also performed. Cefotaxime resistant

    E
    . coli isolates were detected in 95 (
    22
    .2%) of the swab samples. Sequencing analysis results showed occurrence of various β-lactamase genes: blaCTX-M-15 (62), blaTEM-
    1b
    (42), blaCMY-2 (
    22
    ), blaCTX-M-3 (16), blaCTX-M-
    1
    (15), blaOXA-
    1
    (
    9
    ) and blaSHV-12 (3) alone or in combination. The most frequently encountered phylogenetic group was group
    A1
    (35.8%), followed by group D2 (
    22
    .
    1
    %),
    B
    1
    (15.8%),
    D1
    (
    9
    .
    5
    %), A0 (
    7
    .
    4
    %),
    B22
    (
    5
    .3%) and
    B23
    (
    4
    .2%), respectively. PMQR genes, aac(
    6
    ’)-Ib-cr,
    qnrS1
    and qnrB10 were detected in 25.3, 10.
    5
    and
    1
    .
    1
    % of the isolates, respectively. While all isolates were susceptible to imipenem and amikacin, resistance rates to non-β-lactam antibiotics ranged from 20.0% for tobramycin to 56.8% for tetracycline. The virulence genes were only detected in 34 (36.2%) of the isolates and this isolates carried single or various combination of virulence genes of iucD, papC, papE,
    f17a
    -A and eaeA. Four isolates were identified as human virulent pandemic CTX-M-15 producing
    E
    . coli
    clone O25
    b
    :ST131/
    B
    2. To the best of our knowledge, this is the first study to show fecal carriage of ESBL/pAmpC type β-lactamase producing
    E
    . coli
    isolates among dogs in Turkey.

  • 香山 滉一郎, 森下 政夫, 張 国鋒
    粉体および粉末冶金
    2006年 53 巻 5 号 419-429
    発行日: 2006年
    公開日: 2006/12/19
    ジャーナル オープンアクセス
    The phase diagrams of the Ni-Mo-
    B
    and Ni-W-
    B
    ternary systems in the region of less than 50mol%
    B
    were constructed by thermodynamic calculation, based on the data obtained by thermodynamic measurement of the related materials. We found three ternary eutectic points and three or two ternary peritecto-eutectic points as follows:
    E1
    :L (1365K, 71.
    5
    mol%Ni-
    6
    .0mol%Mo-
    22
    .
    5
    mol%
    B
    )=(Ni)+
    Ni3B
    +
    NiMo2B2

    E2
    :L (1355K, 62.
    5
    mol%Ni-2.
    5
    mol%Mo-30.
    5
    mol%
    B
    )=
    Ni3B
    +
    Ni2B
    +
    NiMo2B2

    E3
    :L (1445K, 42.0mol%Ni-30.
    6
    mol%Mo-10.3mol%
    B
    )=(Ni)+NiMo+
    NiMo2B2

    P1
    :L (1812K, 34.
    9
    mol%Ni-42.3mol%Mo-
    22
    .8mol%
    B
    )+MoB=
    Mo2B
    +
    NiMo2B2

    P2:L (1633K, 42.3mol%Ni-40.
    4
    mol%Mo-17.3mol%
    B
    )+Mo=
    Mo2B
    +
    NiMo2B2

    P3:L (1812K, 53.
    5
    mol%Ni-33.
    7
    mol%Mo-12.8mol%
    B
    )+Mo=NiMo+
    NiMo2B2

    E1
    :L (1622K, 51.0mol%Ni-31.
    6
    mol%W-17.
    4
    mol%
    B
    )=(Ni)+W+
    NiW2B2

    E2
    :L (1260K, 71.0mol%Ni-
    7
    .0mol%W-
    22
    .0mol%
    B
    )=(Ni)+
    Ni3B
    +
    NiW2B2

    E3
    :L (1291K, 65.
    4
    mol%Ni-
    4
    .8mol%W-29.8mol%
    B
    )=
    Ni2B
    +
    Ni3B
    +
    NiW2B2

    P1
    :L (2115K, 23.8mol%Ni-43.
    1
    mol%W-33.
    1
    mol%
    B
    )+WB=
    W2B
    +
    NiW2B2

    P2:L (1657K, 48.
    9
    mol%Ni-33.
    1
    mol%W-18.0mol%
    B
    )+
    W2B
    =W+
    NiW2B2

    The calculated phase diagrams are expected to be useful for the development of new Ni-based heat-, corrosion- or wear-resistance alloys.
  • Yasuyuki Gono, Manabu Fujioka, Tamotsu Toriyama
    Journal of the Physical Society of Japan
    1970年 29 巻 2 号 255-258
    発行日: 1970/08/05
    公開日: 2007/06/01
    ジャーナル 認証あり
    The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the Tb152 activity. The L-subshell electron lines of the 586.
    7
    keV
    22
    +→21+ transition are separated by the ion-free beta-ray spectrometer. The M
    1
    -
    E
    2 mixing ratio, δ2, and the dimensionless ratio X of
    E
    0-
    E
    2 mixing of the 586.
    7
    keV transition are obtained to be δ2≤0.16 and 0.034≤X≤0.038, respectively. The
    E
    2 branching ratio
    B
    (
    E
    2;
    22
    +→0g+):
    B
    (
    E
    2;
    22
    +→21+):
    B
    (
    E
    2;
    22
    +→01+) is determined to be 0.023 :
    1
    .0 :
    5
    .
    6
    .
  • 黒川 美貴雄, 吉田 耕治, 永井 保嵩, 宇野 準
    Chemical and Pharmaceutical Bulletin
    1983年 31 巻 12 号 4312-4318
    発行日: 1983/12/25
    公開日: 2008/03/31
    ジャーナル フリー
    Two new partially saturated tricyclic ring systems,
    6
    ,
    6
    a,
    7
    , 8,
    9
    , 10, 10a, 11-octahydro-11-oxodibenz [
    b
    ,
    e
    ] oxepins (3a and 3
    b
    ), and -thiepins (
    4
    a and
    4
    b
    ) were synthesized. Compounds
    4
    a and
    4
    b
    were desulfurized to give a pair of isomeric 2-methylbenzoylcyclohexanes (10a and 10
    b
    ). Deuterated
    4
    a and
    4
    b
    (11a and 11
    b
    ) were prepared starting from butadiene-
    d6
    (12). The stereochemical features of 3a (trans), 3
    b
    (cis),
    4
    a (trans) and
    4
    b
    (cis) are compared with those of 10a, 10
    b
    , 11a and 11
    b
    on the basis of proton nuclear magnetic resonance data.
  • Nicholas ISYUMOV, Eric HO, Peter KING, David SURRY, Barry VICKERY
    日本風工学会誌
    2010年 35 巻 4 号 265-271
    発行日: 2010/10/31
    公開日: 2011/04/01
    ジャーナル フリー
  • N. YOSHIDA, N.R. MORGENSTERN, D.H. CHAN
    土質工学会論文報告集
    1991年 31 巻 1 号 121-130
    発行日: 1991/03/15
    公開日: 2008/02/29
    ジャーナル フリー
    Some existing analytical methods which have been used in geotechnical engineering are modified to handle the shear strength reduction with time due to softening in fissured, over-consolidated clays and mudstones. These are limit equilibrium analysis of slope stability, calculation of earth pressure and calculation of stress and displacement around a tunnel. The softening effect is incorporated in these analyses using the failure criterion and the time-dependent strength parameters proposed previously by the authors. Examples are presented which emphasize the importance of appreciating the softening effect in analyses and further illustrate that the effect of shear strength reduction with time due to softening could easily be captured with existing analytical methods.
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