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  • Grover Loening
    日本航空学会誌
    1963年 11 巻 119 号 373-380
    発行日: 1963年
    公開日: 2009/05/25
    ジャーナル フリー
  • Suguru TAKATSUTO, Kiyomi KOBAYASHI, Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE
    Agricultural and Biological Chemistry
    1988年 52 巻 12 号 3217-3218
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • Keishi Hata, Fuyuki Sugawara, Naganori Ohisa, Saori Takahashi, Kazuyuki Hori
    Biological and Pharmaceutical Bulletin
    2002年 25 巻 8 号 1040-1044
    発行日: 2002年
    公開日: 2002/08/01
    ジャーナル フリー
    We screened the differentiation-inducing activities of 39 mushroom extracts from Akita prefecture, Japan, on the mouse osteoblastic cell line, MC3T3-
    E
    1. Sixteen phosphate buffered saline (PBS), 8 boiled PBS, 14 ethanol and 12 methanol extracts induced alkaline phosphatase (ALP) activities, an indicator of MC3T3-
    E
    1 cell differentiation. The enzyme activities were markedly induced by extracts of Tricholoma auratum, and we isolated the active compound from methanol extracts of this mushroom. Physical data for the isolated active compound were identical to those for (
    22E
    ,24R)-ergosta-
    7
    ,
    22
    -diene-3β,
    ,
    -triol (1). 1 induced ALP activities of MC3T3-
    E
    1 cells and promoted cell proliferation. To investigate the relationships between the chemical structure and differentiation-inducing activity of the compound, ALP-inducing activities of MC3T3-
    E
    1 cells by 1, ergosterol (2), ergocalciferol (3), cholesta-3β,
    ,
    -triol (4),
    7
    -dehydrocholesterol (
    5
    ) and cholecalciferol (
    6
    ) were tested. The enzyme activities of MC3T3-
    E
    1 cells were increased 3.0-fold by 10 μM 1 and 2.4-fold by 10 μM 4. However, 2, 3,
    5
    and
    6
    did not induce MC3T3-
    E
    1 cell ALP activity at 0.1—10 μM. These results suggested that the OH groups at C-
    5
    and/or C-
    6
    of 1 and 4 played an important role in their differentiation-inducing activities on MC3T3-
    E
    1 cells. Furthermore, 1 suppressed induction of MC3T3-
    E
    1 cell apoptosis by serum starvation.
  • Joey
    B
    . Tanney, Leonard J. Hutchison
    Mycoscience
    2012年 53 巻 1 号 31-35
    発行日: 2012年
    公開日: 2023/03/31
    ジャーナル オープンアクセス

    The ability of Climacodon septentrionalis to immobilize and kill a mycophagous nematode (Aphelenchoides sp.) in vitro is described for the first time. Two isolates produced droplets (20–45 μm in diameter) that formed at the apices of tall, stalked, and branching secretory cells (700–1,500 μm tall). On 2% modified malt extract agar, nematodes became enveloped in the droplets, which restricted their ability to move and resulted in complete immobilization and death within several hours of contact. The rate of decomposition of the nematodes varied considerably, with most individuals persisting for weeks whereas others were degraded within several days and appeared to be colonized by dense hyphal growth. This study provides the first documentation of a non-agaricoid fungus producing secretory cells that are able to immobilize nematodes.

  • Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE, Kiyomi KOBAYASHI, Suguru TAKATSUTO
    Agricultural and Biological Chemistry
    1988年 52 巻 8 号 2117-2118
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • Yasuyuki Gono, Manabu Fujioka, Tamotsu Toriyama
    Journal of the Physical Society of Japan
    1970年 29 巻 2 号 255-258
    発行日: 1970/08/05
    公開日: 2007/06/01
    ジャーナル 認証あり
    The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the Tb152 activity. The L-subshell electron lines of the 586.
    7
    keV
    22
    +→21+ transition are separated by the ion-free beta-ray spectrometer. The M1-
    E
    2 mixing ratio, δ2, and the dimensionless ratio X of
    E
    0-
    E
    2 mixing of the 586.
    7
    keV transition are obtained to be δ2≤0.16 and 0.034≤X≤0.038, respectively. The
    E
    2 branching ratio
    B
    (
    E
    2;
    22
    +→0g+):
    B
    (
    E
    2;
    22
    +→21+):
    B
    (
    E
    2;
    22
    +→01+) is determined to be 0.023 : 1.0 :
    5
    .
    6
    .
  • Yukichi Yamaguchi, Jian-zhi Runan(Gen), Teruaki Nagahara
    Journal of the Physical Society of Japan
    1975年 38 巻 4 号 911-916
    発行日: 1975/04/15
    公開日: 2007/06/01
    ジャーナル 認証あり
    The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the 116mIn activity. Directional correlations are also measured for 818–1293 and 1097–1293 keV cascades. The M1-
    E
    2 mixing ratio δ, and the
    E
    0-
    E
    2 mixing ratio μk are obtained for 818.
    7
    keV
    22
    +→21+ transition to be δ=1.52
    0.22
    +0.26, and μk
    6
    .1×10−4 respectively. The
    E
    2 branching ratio
    B
    (
    E
    2;
    22
    +→0g+):
    B
    (
    E
    2;
    22
    +→21+):
    B
    (
    E
    2;
    22
    +→01+) is determined to be 0.0158:1.0:
    5
    .86.
  • A.M. BRITTO, C. SAVVIDOU, M.J. GUNN, J.R. BOOKER
    土質工学会論文報告集
    1992年 32 巻 1 号 13-25
    発行日: 1992/03/15
    公開日: 2008/02/29
    ジャーナル フリー
    One method currently being considered for the disposal of high level radio-active waste is burial in the seabed. When a hot object is buried in soil, the temperature of the soil adjacent to the object is raised and there is transient heat flow away from the object. The rise in the temperature of the soil causes excess pore pressures to be generated and transient pore water diffusion also takes place. A finite element formulation of the coupled heat flow and consolidation problem is presented. The computer implementation of this formulation is found to compare favourably with analytical solutions based on the same physical principles.
  • 佐藤 敬之輔
    デザイン学研究
    1970年 1970 巻 11 号 45-55
    発行日: 1970/03/30
    公開日: 2017/07/25
    ジャーナル フリー
    [1] The purpose of this reserch is to make clear what type of design can give good effects to win the high readership score. At the begining I had to know what factors decide the readership score, and how to change the quality of the desing into numerical value. I have used the method of multi-dimentional analysis with the help of a computer, and got the estimation formula, with
    7
    kinds of factors, as follows ; A^^〜=
    B
    +C+D+K+
    aE
    +bF+cG. A^^〜=estimated values of the readership score. 1)
    B
    , C, D, K : these four factors are given as category values (so we call them); each factor is classified into several categories.
    B
    =week day, classified into
    7
    categories. C=pages of a newspaper, which are characterized by the kinds of articles, news, and the other reading matters, classified into
    22
    categories. D=kinds of goods and trades of the advertizement, classified into 14 catedories. K=constants, given to each 13 surveys. 2)
    E
    , F, G : these factors are given as numerical values. G=area of advertizement, measured by the unit of column in the whole page length, being classified into
    6
    kinds of area (2.
    5
    , 3.
    5
    ,
    5
    ,
    7
    , 10, 15) and 15 column means a whole page, about 2,000cm^2.
    E
    , F are the marks obtained in the design of advertizements.
    E
    =sum of the marks obtained in each design element on the advertizement. F=the marks obtained on the whole effect of the design. 3) a,
    b
    , c : coefficients Using the above formula with the category values and the coefficients, we can obtain the naked design effect from the actual value A of readership score:
    aE
    +bF=A-(
    B
    +C+D+K+cG). In this research, I used 1,829 data of readership score from 1960 to 1968, being obtained by 13 survevs, spring and autumn twice a year. The sample of size each survey was 3,541, 2,251, or 200 in the other 11 surveys. Multiple correlation coefficient between the estimated value A^^〜 and the actual value A is 0.951. The table 2^* shows the contribution indexes of each factor by 3 kinds of expression-(1) Range : the absolute difference between the maximum and the minimum category values, (2) Standard deviations of the category values, (3) Partial correlation coefficient : the relationship between the actual values A and each factors. *see the table 2 in the thesis in Japanese. [2] The important point was in the determination of the values of
    E
    , F.
    E
    is the sum of the marks obtained in each design element, classified into four kinds :
    E
    =
    E
    _1+
    E
    _2+
    E
    _3+
    E
    _4. design elements [table]
    E
    _1,
    E
    _2,
    E
    _3,
    E
    _4, these values have the
    5
    grades, as 0, 1, 2, 3, 4 and 0 is given to the design that has no attractive effect or no applicable element. And
    E
    obtain the marks of 0 to
    9
    grades as the sum of them. The values of F have also
    5
    grades, 0 to 4. The principles to determine the values of
    E
    , F are as follows : a) The marks obtained of
    E
    , F must be the relative values among the each survey, and at the same time, they must have constancy within the same survey-the same elements of design must win the same marks obtained.
    b
    ) They must be determined as to win the highest multiple correlation coefficient, when they are put into the estimation formula. c) They must be reasonable. In order to justify them, we must carry many researches on the actual condition. The frequency of accurence of each grade of
    E
    , F values, as the table
    5
    -4, and
    5
    -
    5
    in the thesis in Japanese.
  • Katsuaki SHIRAI, Takeo SAKAI, Momo FUKUDA, Tatsuya OIKE
    Journal of Veterinary Medical Science
    1998年 60 巻 3 号 291-293
    発行日: 1998年
    公開日: 2001/10/06
    ジャーナル フリー
    A monoclonal antibody,
    6
    E
    9
    established from mice injected with dolphin peripheral blood lymphocytes (PBLs) was characterized. In addition to its reactivity against
    89
    .4% of dolphin PBLs,
    6
    E
    9
    reacted with 33.1% of bovine PBLs of which
    22
    % were CD
    5
    +, 11.1% were
    CD5
    -.
    6
    E
    9
    recognized a 34 kD protein on the surface of dolphin and bovine PBLs. Analysis of the protein's N-terminal amino acid sequence indicated that
    6
    E
    9
    recognizes bovine major histocompatibility complex (MHC) class II antigens. These results suggested that
    6
    E
    9
    recognized MHC class II antigens on bovine PBLs. As we have already produced an anti-dolphin MHC class I monoclonal antibody, analysis of immune system using these monoclonal antibodies will advance our understanding of the evolution of the mammalian immune system.
  • 黒川 美貴雄, 吉田 耕治, 永井 保嵩, 宇野 準
    Chemical and Pharmaceutical Bulletin
    1983年 31 巻 12 号 4312-4318
    発行日: 1983/12/25
    公開日: 2008/03/31
    ジャーナル フリー
    Two new partially saturated tricyclic ring systems,
    6
    ,
    6
    a,
    7
    , 8,
    9
    , 10, 10a, 11-octahydro-11-oxodibenz [
    b
    ,
    e
    ] oxepins (3a and 3
    b
    ), and -thiepins (4a and 4
    b
    ) were synthesized. Compounds 4a and 4
    b
    were desulfurized to give a pair of isomeric 2-methylbenzoylcyclohexanes (10a and 10
    b
    ). Deuterated 4a and 4
    b
    (11a and 11
    b
    ) were prepared starting from butadiene-
    d6
    (12). The stereochemical features of 3a (trans), 3
    b
    (cis), 4a (trans) and 4
    b
    (cis) are compared with those of 10a, 10
    b
    , 11a and 11
    b
    on the basis of proton nuclear magnetic resonance data.
  • M. L. GHOSH
    Journal of Physics of the Earth
    1972年 20 巻 2 号 165-186
    発行日: 1972年
    公開日: 2009/04/30
    ジャーナル フリー
    The possibility of attenuation of microseismic waves due to the presence of an upward folding of the ocean bottom into the liquid is discussed in this paper. The upward folding of the ocean bottom has been idealized by means of an irregularity in the form of a rectangle intruding into the liquid and the evaluation of the displacement component at any point of the solid medium has been carried out in two stages. First, the change in the incident mode of the surface wave due to the presence of the rectangular irregularity has been determined, and second, the subsequent change of the resulting displacement components due to the termination of the liquid layer and the step change in elevation of the solid medium at the continental margin has been discovered. Finally, numerical calculation has been made to determine the attenuation of the microseismic waves of different periods due to the presence of the rectangular irregularity at the ocean bottom.
  • 高津戸 秀, 池川 信夫
    Chemical and Pharmaceutical Bulletin
    1984年 32 巻 5 号 2001-2004
    発行日: 1984/05/25
    公開日: 2008/03/31
    ジャーナル フリー
    Brassinolide analogues, (
    22
    R, 23R, 24R)-2α, 3α,
    22
    , 23-tetrahydroxy-
    B
    -homo-
    7
    -oxa-
    -ergostan-
    6
    -one (24-epibrassinolide) (10) and (
    22
    S, 23S, 24R)-2α, 3α,
    22
    , 23-tetrahydroxy-
    B
    -homo-
    7
    -oxa-
    -ergostan-
    6
    -one (
    9
    ), were synthesized from brassicasterol (3a) in five steps and with ca. 20% overall yield. The key steps are the direct formation of (
    22
    E
    , 24R)-3α,
    5
    -cyclo-
    -ergost-
    22
    -en-
    6
    -one (4) from brassicasterol mesylate (3
    b
    ), the acid-catalyzed rearrangement of 4 to (
    22
    E
    , 24R)-
    -ergosta-2,
    22
    -dien-
    6
    -one (
    6
    ), and the Baeyer-Villiger oxidation of the tetrahydroxy
    -ergostan-
    6
    -ones
    7
    and 8.
  • 琴尾 幸徳, 石川 成実, 田辺 順子, 御園 生尭久
    日本化学会誌(化学と工業化学)
    1980年 1980 巻 9 号 1391-1396
    発行日: 1980/09/10
    公開日: 2011/05/30
    ジャーナル フリー
    Nアルキル3,4:
    9
    ,10-ペリレンテトラカルボン酸モノアンヒドリド=モノイミド[4a~
    e
    ]と芳香族アミン(アニリン,p-トルイジン,p-アニシジン,3,
    5
    -キシリジン,4-アミノナゾベンゼン,およびo-フェニレンジアミン)を縮合して非対称型3,4:
    9
    ,10-ペリレンビス(ジカルボキシミド)誘導体-N-アルキル-N'-アリール-3,4:
    9
    ,10-ペリレンビス(ジカルボキシミド)(〔
    5
    a~
    e
    〕,〔
    6
    a~
    e
    〕,〔
    7
    a~
    e
    〕,〔8a~
    e
    〕,〔
    9
    a~
    e
    〕,および〔10a~
    b
    〕)を合成した. これらの各誘導体はすべて赤色系の色相を示し, 顔料試験の結果N-ブチル-N'-アリール-3,4:
    9
    ,10-ペリレンビス(ジカルボキシミド)(たとえば〔
    5
    e
    〕や〔
    6
    e
    〕)がとくにすぐれた耐光性を示した.
  • 香山 滉一郎, 森下 政夫, 張 国鋒
    粉体および粉末冶金
    2006年 53 巻 5 号 419-429
    発行日: 2006年
    公開日: 2006/12/19
    ジャーナル オープンアクセス
    The phase diagrams of the Ni-Mo-
    B
    and Ni-W-
    B
    ternary systems in the region of less than 50mol%
    B
    were constructed by thermodynamic calculation, based on the data obtained by thermodynamic measurement of the related materials. We found three ternary eutectic points and three or two ternary peritecto-eutectic points as follows:
    E1
    :L (1365K, 71.
    5
    mol%Ni-
    6
    .0mol%Mo-
    22
    .
    5
    mol%
    B
    )=(Ni)+
    Ni3B
    +
    NiMo2B2

    E2
    :L (1355K, 62.
    5
    mol%Ni-2.
    5
    mol%Mo-30.
    5
    mol%
    B
    )=
    Ni3B
    +
    Ni2B
    +
    NiMo2B2

    E3
    :L (1445K, 42.0mol%Ni-30.
    6
    mol%Mo-10.3mol%
    B
    )=(Ni)+NiMo+
    NiMo2B2

    P1:L (1812K, 34.
    9
    mol%Ni-42.3mol%Mo-
    22
    .8mol%
    B
    )+MoB=
    Mo2B
    +
    NiMo2B2

    P2:L (1633K, 42.3mol%Ni-40.4mol%Mo-17.3mol%
    B
    )+Mo=
    Mo2B
    +
    NiMo2B2

    P3:L (1812K, 53.
    5
    mol%Ni-33.
    7
    mol%Mo-12.8mol%
    B
    )+Mo=NiMo+
    NiMo2B2

    E1
    :L (1622K, 51.0mol%Ni-31.
    6
    mol%W-17.4mol%
    B
    )=(Ni)+W+
    NiW2B2

    E2
    :L (1260K, 71.0mol%Ni-
    7
    .0mol%W-
    22
    .0mol%
    B
    )=(Ni)+
    Ni3B
    +
    NiW2B2

    E3
    :L (1291K, 65.4mol%Ni-4.8mol%W-29.8mol%
    B
    )=
    Ni2B
    +
    Ni3B
    +
    NiW2B2

    P1:L (2115K, 23.8mol%Ni-43.1mol%W-33.1mol%
    B
    )+WB=
    W2B
    +
    NiW2B2

    P2:L (1657K, 48.
    9
    mol%Ni-33.1mol%W-18.0mol%
    B
    )+
    W2B
    =W+
    NiW2B2

    The calculated phase diagrams are expected to be useful for the development of new Ni-based heat-, corrosion- or wear-resistance alloys.
  • 古市 憲史, 田中 昌博, 川添 発彬
    日本補綴歯科学会雑誌
    1998年 42 巻 1 号 74-83
    発行日: 1998/02/01
    公開日: 2010/08/10
    ジャーナル フリー
    Between April 1, 1987 and August
    7
    , 1997, a total of 128 abutment teeth associated with 34 telescope removable partial dentures in 28 patients (
    22
    females and
    6
    males) who had a mean age of 57.4±
    9
    .3 years was observed. The survival time (with extraction being the endpoint) for each abutment tooth was calculated using Kaplan-Meier analysis. Significance levels were determined using 8 prognostic factors for 4 statistical tests, i.
    e
    ., the generalized Wilcoxon, the Cox-Mantel, the Logrank, and the Mantel-Haenszel tests. Furthermore, survival estimates and relative risks were calculated by Cox hazard regression.
    The results conclusively indicated a higher survival for vital as compared to endodontically-treated teeth. The relative risk of an abutment tooth adjacent to a free-end saddle was
    5
    .
    81
    . The risk increased by 2.79 for each group from molar to cuspid, to premolar, and to incisor. The survival estimate was
    89
    .8% at
    9
    -10 years after placement of the denture.
  • T BAKER, C. RANGACHARYULU
    日本物理学会講演概要集
    1999年 54.2.1 巻 23pSM-6
    発行日: 1999/09/13
    公開日: 2018/03/04
    会議録・要旨集 フリー
  • Sen-fang Sui, Erich Sackmann
    The Journal of Biochemistry
    1992年 111 巻 1 号 129-138
    発行日: 1992年
    公開日: 2008/11/18
    ジャーナル フリー
    In the first part of the present work the interaction of glycophorin with dimyristoylphosphatidylcholine (DMPC) is studied by freeze fracture electron microscopy, densitometry, calorimetry, and 90° static light scattering. An exothermic lipid/protein interaction energy of WP=190 kJ•mol-1 was found by application of the well known Van Laar relation for the displacement of the freezing point and the Gibbs-Duhem relationship. Secondly, the effects of Ca2+ on the lipid/protein interaction were studied. Following Ca2+ addition a remarkable decoupling of the interaction of the glycophorin head group with the bilayer surface was revealed by densitometry and gold-labeling electron microscopy. It is estimated that about 80% of lipid once disturbed by the adsorption of glycophorin head groups is decoupled after addition of Ca2+. Thirdly, the selective interaction of glycophorin with binary lipid mixtures was studied, including the mixtures of DMPC with dimyristoylphosphatidylserine (DMPS) and dilauroylphosphatidylcholine (DLPC), and the mixture of dipalmitoylphosphatidylcholine (DPPC) with DLPC.
  • Yasunori YAOITA, Keiko AMEMIYA, Hiroyuki OHNUMA, Katsuyuki FURUMURA, Akihiro MASAKI, Toshihiko MATSUKI, Masao KIKUCHI
    Chemical and Pharmaceutical Bulletin
    1998年 46 巻 6 号 944-950
    発行日: 1998/06/15
    公開日: 2008/03/31
    ジャーナル フリー
    Eight new sterols,
    , 8α-epidioxy-(
    22
    E
    , 24R)-23-methylergosta-
    6
    ,
    22
    -dien-3β-ol (1), 3β,
    ,
    -trihydroxy-(
    22
    E
    , 24R)-23-methylergosta-
    7
    ,
    22
    -dien-
    6
    -one (2), 3β,
    ,
    -trihydroxy-(24S)-ergost-
    7
    -en-
    6
    -one (3), 3β,
    ,
    , 14α-tetrahydroxy-(
    22
    E
    , 24R)-ergosta-
    7
    ,
    22
    -dien-
    6
    -one (4), (
    22
    E
    , 24R)-ergosta-
    7
    ,
    22
    -diene-3β,
    ,
    ,
    -tetrol (
    5
    ),
    ,
    -epidioxy-3β-hydroxy-(
    22
    E
    , 24R)-ergosta-
    7
    ,
    22
    -dien-
    6
    -one (
    6
    ),
    ,
    -epidioxy-3β-hydroxy-(24S)-ergost-
    7
    -en-
    6
    -one (
    7
    ) and
    ,
    -epoxy-(
    22
    E
    , 24R)-ergosta-8,
    22
    -diene-3β,
    , 14α-triol (8), have been isolated from five edible mushrooms, Lentinus edodes, Flammulina velutipes, Hypsizigus marmoreus, Pleurotus ostreatus and Pholiota nameko together with fifteen known ones (
    9
    -23), of which two (16 and 17) are reported for the first time from a fungal source. The structures of these new compounds were elucidated on the basis of their spectral data.
  • 第1編血清蛋白との結合について
    橋本 孝夫
    CHEMOTHERAPY
    1973年 21 巻 1 号 38-44
    発行日: 1973/01/25
    公開日: 2011/03/08
    ジャーナル フリー
    The binding of penicillin G and other 29 antibiotics to the bovine plasma proteins, a part of the pharmacokinetics of antibiotics, was investigated by the ultrafiltrating technique at 4°C.
    As the rates of the binding, inactivation, recovery and binding activity, following values were obtained in order : 64.
    9
    to 82.
    7
    %, 11. 96 to 56. 85%,
    7
    . 77 to 25. 75% and 8.
    9
    to 34. 11% in penicillin antibiotics; 0 to 61. 4%, 0 to 10. 66%, 0. 49 to 12. 8% and 14.
    91
    to 41. 72% in glycoside antibiotics;
    91
    . 0 to 99.
    9
    %, 16. 0 to 46. 19%, 44. 98 to 71. 01% and 4. 33 to 21. 06% in tetracycline antibiotics; 55.
    22
    to
    94
    . 1%,
    5
    . 37 to 57. 36%, 1. 32 to 31.
    5
    % and
    9
    . 66 to 40. 65% in macrolide antibiotics; and 72.
    6
    to 95. 68%, 14. 34 to 51. 85%, 8. 19 to 30. 12%, and 17. 28 to 41. 54% in chloramphenicol antibiotics, respectively.
    Optimum pH of the binding of antibiotics to the plasma proteins was in the range
    5
    . 0 to 8. 0, i.
    e
    . 8. 0 in penicillin antibiotics,
    5
    . 0 in glycoside antibiotics,
    7
    . 0 to 8. 0 in tetracycline antibiotics,
    6
    . 0 to
    7
    . 0 in macrolide antibiotics, and
    7
    . 0 to 8. 0 in chloramphenicol antibiotics, respectively.
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