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  • 小田切 孝人, 田代 眞人
    ウイルス
    2013年 63 巻 2 号 233-240
    発行日: 2013/12/25
    公開日: 2014/10/31
    ジャーナル フリー
  • George W. Lee
    燃料協会誌
    1973年 52 巻 3 号 171-177
    発行日: 1973/03/20
    公開日: 2010/06/28
    ジャーナル フリー
  • Grover Loening
    日本航空学会誌
    1963年 11 巻 119 号 373-380
    発行日: 1963年
    公開日: 2009/05/25
    ジャーナル フリー
  • I.
    F
    . Davies
    Journal of Light & Visual Environment
    1984年 8 巻 1 号 1_9-1_20
    発行日: 1984年
    公開日: 2011/05/20
    ジャーナル フリー
  • 山本 雅史, Abkenar Asad Asadi, 松本 亮司, 根角 博久, 吉田 俊雄, 國賀 武, 久保 達也, 冨永 茂人
    園芸学会雑誌
    2007年 76 巻 1 号 36-40
    発行日: 2007年
    公開日: 2007/03/06
    ジャーナル フリー
    カンキツ主要12種を用いて染色体のクロモマイシン
    A3
    (CMA) 染色を行った.染色体は CMA(+) バンドの有無および位置から
    7
    種類に区分できた.すなわち,CMA(+) を A: 両端および動原体近傍に有する,
    B
    : 一方の端部と動原体近傍に有する,C: 両端に有する,
    D
    : 一方の端部に有する,
    E
    : CMA(+) がない,
    F
    : 動原体近傍に有する,Dst: 付随染色体を有する
    D
    型,である.各種はこれらのうち
    2
    6
    種類の染色体を有し,独自の CMA バンドパターンを示した.C. medica では
    2
    B
    +
    8
    D
    +
    8
    E
    C. limon では 1
    B
    + 1C +
    8
    D
    +
    8
    E
    C. aurantifolia では
    2
    B
    +
    9
    D
    +
    7
    E
    C. aurantium では 1A + 1
    B
    + 1C +
    7
    D
    +
    8
    E
    C. sinensis では
    2
    B
    +
    2
    C +
    7
    D
    +
    7
    E
    C. maxima では
    3
    A +
    3
    C + 4
    D
    +
    8
    E
    C. paradisi では
    2
    A +
    3
    C +
    6
    D
    +
    7
    E
    C. ichangensis では
    2
    B
    +
    2
    C + 12
    D
    +
    2
    E
    C. latipes では
    2
    A +
    5
    C +
    8
    D
    +
    3
    E
    C. micrantha では 1
    B
    + 11
    D
    + 4
    E
    +
    2
    Dst,C. macroptera では
    2
    B
    + 1C + 11
    D
    +
    3
    E
    + 1
    F
    C. hystrix では
    3
    B
    + 1C +
    8
    D
    +
    3
    E
    +
    2
    F
    + 1Dst であった.
  • 財満 鎮雄, 竹内 洋一郎, 入交 裕
    軽金属
    1975年 25 巻 8 号 310-313
    発行日: 1975/08/30
    公開日: 2008/07/23
    ジャーナル フリー
    The modulns of longitudinal elasticity and their temperature dependence in commercial aluminum cast alloys were measured in the temperature range from room temperature (20°C) to 250°C by the resonant frequency method. The results obtained are as follows:
    The modulus of longitudinal elasticity tended to decrease weakly and linearly (the tangent of its decrease, m = (-
    2
    .4--
    3
    .
    3
    ) × 102kg/
    cm2
    /°C) with the rise of temperature. Within the range of the experiments, aluminum cast alloys were divided into
    3
    groups, the lst group materials having large moduli of elasticity
    E0
    at room temperature (i.
    e
    .,
    E0
    = (
    7
    .15-
    7
    .25) × 105kg/
    cm2
    ) were AC
    2
    A-T
    6
    , AC
    3
    A-
    F
    , AC4A-
    F
    , AC4A-T4, AC4
    B
    -
    F
    , AC4
    B
    -T4, AC
    8
    A-
    F
    , AC
    8
    A-T4, etc., the
    2
    nd group materials having intermediate moduli (i.
    e
    .,
    E0
    = (
    6
    .
    85
    -
    6
    .98) × 105kg/
    cm2
    ) were AC4C-
    F
    , AC4C-T
    5
    , AC4C-T
    6
    , AC4
    D
    -
    F
    , AC4
    D
    -T
    6
    , AC
    7
    A-
    F
    , etc. and the
    3
    rd group materials showing considerably smaller moduli (i.
    e
    .,
    E0
    = (
    6
    .58-
    6
    .65) × 105kg/
    cm2
    ) were AC1A-
    F
    , AC1A-T
    6
    , AC
    2
    A-
    F
    , etc. However, there were some differences between the moduli in this experiments and the moduli in the other data books, and these were considered due to the difference of the measurement principles and of hypotheses or assumptions involved in these principles, so it is suggested that the moduli of elasticity should be reported with indication of the measuring method.
  • 黒川 美貴雄, 吉田 耕治, 永井 保嵩, 宇野 準
    Chemical and Pharmaceutical Bulletin
    1983年 31 巻 12 号 4312-4318
    発行日: 1983/12/25
    公開日: 2008/03/31
    ジャーナル フリー
    Two new partially saturated tricyclic ring systems,
    6
    ,
    6
    a,
    7
    ,
    8
    ,
    9
    , 10, 10a, 11-octahydro-11-oxodibenz [
    b
    ,
    e
    ] oxepins (
    3
    a and
    3
    b
    ), and -thiepins (4a and 4
    b
    ) were synthesized. Compounds 4a and 4
    b
    were desulfurized to give a pair of isomeric
    2
    -methylbenzoylcyclohexanes (10a and 10
    b
    ). Deuterated 4a and 4
    b
    (11a and 11
    b
    ) were prepared starting from butadiene-
    d6
    (12). The stereochemical features of
    3
    a (trans),
    3
    b
    (cis), 4a (trans) and 4
    b
    (cis) are compared with those of 10a, 10
    b
    , 11a and 11
    b
    on the basis of proton nuclear magnetic resonance data.
  • Özkan ASLANTAŞ, Ebru Şebnem YILMAZ
    Journal of Veterinary Medical Science
    2017年 79 巻 6 号 1024-1030
    発行日: 2017年
    公開日: 2017/06/16
    [早期公開] 公開日: 2017/04/27
    ジャーナル フリー

    This study aimed to determine the prevalence of fecal carriage of extended spectrum β-lactamase (ESBL) and/or plasmidic AmpC β-lactamase (pAmpC) producing Escherichia coli among dogs (n=428) in Turkey. Polymerase chain reaction (PCR) and sequencing were used to characterize genes encoding β-lactamase and plasmid mediated quinolone resistance (PMQR). Antimicrobial susceptibility testing and PCRs for virulence genes and phylogenetic groups were also performed. Cefotaxime resistant

    E
    . coli isolates were detected in 95 (
    22
    .
    2
    %) of the swab samples. Sequencing analysis results showed occurrence of various β-lactamase genes: blaCTX-M-15 (62), blaTEM-
    1b
    (42), blaCMY-
    2
    (
    22
    ), blaCTX-M-
    3
    (16), blaCTX-M-1 (15), blaOXA-1 (
    9
    ) and blaSHV-12 (
    3
    ) alone or in combination. The most frequently encountered phylogenetic group was group A1 (35.
    8
    %), followed by group
    D2
    (
    22
    .1%),
    B
    1 (15.
    8
    %),
    D1
    (
    9
    .
    5
    %),
    A0
    (
    7
    .4%),
    B22
    (
    5
    .
    3
    %) and
    B23
    (4.
    2
    %), respectively. PMQR genes, aac(
    6
    ’)-Ib-cr, qnr
    S1 and qnrB10 were detected in 25.
    3
    , 10.
    5
    and 1.1% of the isolates, respectively. While all isolates were susceptible to imipenem and amikacin, resistance rates to non-β-lactam antibiotics ranged from 20.
    0
    % for tobramycin to 56.
    8
    % for tetracycline. The virulence genes were only detected in 34 (36.
    2
    %) of the isolates and this isolates carried single or various combination of virulence genes of iucD, papC, papE,
    f17a
    -A and eaeA. Four isolates were identified as human virulent pandemic CTX-M-15 producing
    E
    . coli
    clone O25
    b
    :ST131/
    B
    2
    . To the best of our knowledge, this is the first study to show fecal carriage of ESBL/pAmpC type β-lactamase producing
    E
    . coli
    isolates among dogs in Turkey.

  • 板倉 智敏, 五藤 精知, 藤原 義昭
    日本獸醫學雜誌(The Japanese Journal of Veterinary Science)
    1973年 35 巻 4 号 289-297_5
    発行日: 1973/08/25
    公開日: 2008/02/13
    ジャーナル フリー
    All the birds examined were also associated with bone dysplasia (art alczaormal develop-ment of bone tissue) in the diaphyseal cortex of the leg bones, especially of bones affectedwith dyschondroplasia. This result is very significant in order to clarifyz tlais disease entity.1970:J14, k -1 }
    7
    )
    7
    , M77 ) i? ht /, ( K )
    7
    (C # L"C, MB @ (
    7
    ) t, If!TB& U "C, Jff Dyschondroplasia (1*t%
    7
    fi!dW) ().g:#
    f
    [!:.fLlt! K?
    3
    o, [1: (
    7
    )M;tC, rff.?U/:cD
    8
    , bb=1lC#li
    6
    *H(DX15RI!!
    D
    & t, r, ccl)Efff
    7
    flr.#.??t"ut:
    2
    .?T<
    3
    .1.?l?
    F
    ?/?t:>"A??1!? >
    E
    >?TMOll?, lI]%G (
    f
    -srRM) -ts;
    5
    ;
    e
    .*BI) *M[t fL 54
    5
    t:.;*.{1*I[l?(), t@Yllll*fJ?H@(
    7
    ) %?Jfipj@ (Dyschondroplasia) p, }, (, 1lTi{-X, WIKIM itt{
    b
    =
    b
    t
    D
    "tl%tff{tO 1111IH(-UP!z
    8
    U-ii) >ES- -)%Wi*fd?1J*[lEj: >11"i
    6
    ifI".*"H*Tl*&Z") #)/
    2
    ?-"k l
    E
    B
    - vich ) J&it(Vh
    3
    iO"= >If-ffi"!1lYl*I4")Ji/l![40111!>
    D
    9
    *
    F
    !)<Y14M)?A"!>CL(Il], k
    7
    .Cl
    8
    T"ltTt*flB1? & $4U [-" C U" L % w, Zl1*.IlBl tI1J, FA(y L-x") LVfAK t: >
    3
    llltPJ4IiI " } ) t- ! Al j: >kP11liR
    6
    , &ffl(C
    5
    NWi Z
    3
    lk(C#L" Ct ?
    f
    !4M
    2
    "C- fL#, -()%
    E
    .IWMd1.XI1*I1EPW(tit ff1lR)
  • 橋口 英俊
    日本医科大学雑誌
    1983年 50 巻 4 号 563-585
    発行日: 1983/08/15
    公開日: 2009/12/04
    ジャーナル フリー
    Thirty-six patients (19 males, 17 females: atypical schizophrenia;
    3
    , typical schizophrenia;
    9
    , depression; 11, neurosis and other psychiatric disorders;
    8
    ) were operated on according to orbitoventromedial undercutting by Hirose. In all cases, the Rorschach test was carried out and daily behaviors were studied. Thirty-one scales of the test were subjected to multivariate analysis whereas the behaviors were evaluated according to the following criteria, i.
    e
    ., A: recovered or symptom free,
    B
    : markedly improved, C: moderately improved,
    D
    : slightly improved and
    E
    : not improved. The following results were obtained.
    1) The evaluation of behaviors is as follows. A: 12 cases,
    B
    :
    9
    , C:
    9
    ,
    D
    :
    6
    ,
    E
    : none.
    2
    ) It was found that scores of
    F
    +106% and R+106% scales were significantly higher after the operation than before; that correlation coefficients between the scores before and after the operation were considerably high.
    3
    ) Factor analysis followed by varimax rotation was carried out. Six factors were extracted, i.
    e
    ., (
    F
    1) sensitivity to emotional stimuli, (
    F
    2
    ) ego-strength, (
    F
    3
    ) obsessional rigidity, (
    F
    4) reaction time, (
    F
    5
    ) anxiety and tension and (
    F
    6
    ) empathy. It was revealed that
    F
    2
    was high in atypical schizophrenia, depression and neurosis, and that
    F
    2
    and
    F
    6
    were significantly different in terms of the factor scores among the four groups A,
    B
    , C and
    D
    ;
    F
    2
    was highest in A, and lowest in
    D
    regardless of whether it was before or after the operation.
    F
    6
    showed high scores in both A and C, and low in
    D
    .
    4) Multiple discriminant analysis was applied to the data of the Rorschach test before the operation, by classifying 36 subjects into the four groups A,
    B
    , C and
    D
    . As a result, high rates of correct diagnosis were obtained, i.
    e
    ., 100% for A, 78% for
    B
    , 56% for C and 100% for
    D
    . When the groups C and
    D
    were combined into one group (C+
    D
    ) the highest percentage (100%) was seen in A, followed by
    B
    (89%) and C+
    D
    group (87%). When the groups A and
    B
    were combined into one group (A+
    B
    ), the percentages of correct diagnosis were 81% for A+
    B
    , and 93% for C+
    D
    .
    In conclusion, it can be said that scales of the Rorschach test have been proved to be valid for predicting mental and physical states after the orbito-ventromedial undercutting.
  • Yanchun Peng, Zitong Yu, Shahidul Islam, Yujuan Zhang, Xiaolong Wang, Zhensheng Lei, Kan Yu, Dongfa Sun, Wujun Ma
    Breeding Science
    2016年 66 巻 4 号 646-652
    発行日: 2016年
    公開日: 2016/09/30
    [早期公開] 公開日: 2016/08/11
    ジャーナル フリー HTML
    電子付録

    Low molecular weight glutenin subunits are important components of wheat storage proteins, which play an important role in determining end-use quality of common wheat. A newly established matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) procedure was used to analyze 478 landraces of bread wheat collected from the Yangtze-River region in China. Results indicated that 17 alleles at three loci: Glu-

    A3
    , Glu-
    B3
    and Glu-
    D3
    were identified, resulting in 87 different allele combinations. Of the 17 alleles detected at all the Glu-
    3
    loci, five belonged to Glu-
    A3
    , seven to Glu-
    B3
    and five to Glu-
    D3
    locus. MALDI-TOF-MS indicated Glu-A
    3
    a/c
    was present in 72.
    8
    %, Glu-
    A3b
    in
    8
    .4%, Glu-
    A3d
    in
    8
    .4%, Glu-
    A3f
    in
    5
    .
    2
    % and Glu-
    A3e
    in
    3
    .
    6
    % lines. Seven types of alleles were identified at the Glu-
    B3
    locus: Glu-
    B
    3
    d
    /i
    (25.
    5
    %), Glu-
    B3b
    (21.
    3
    %), Glu-
    B3c
    (16.
    9
    %), Glu-
    B3h
    (13.
    8
    %), Glu-
    B3f
    (
    8
    .4%), Glu-
    B3a
    (
    8
    .
    2
    %), and Glu-
    B3g
    (
    5
    .
    2
    %). Five types of Glu-
    D3
    alleles were detected: Glu-
    D3a
    (58.4%), Glu-
    D3c
    (
    22
    .
    6
    %), Glu-
    D3d
    (15.
    5
    %), Glu-
    D3b
    (
    3
    .
    3
    %) and Glu-
    D3f
    (
    0
    .
    2
    %). Four new alleles that showed abnormal MALDI-TOF spectrum patterns were identified at the Glu-
    A3
    and Glu-
    B3
    loci. A detailed study is needed to further characterize these alleles and their potential usage for wheat improvement.

  • 黒川 美貴雄, 糸川 彰, 松本 純一, 福本 吉久, 月原 冨武
    Chemical and Pharmaceutical Bulletin
    1992年 40 巻 9 号 2270-2274
    発行日: 1992/09/25
    公開日: 2008/03/31
    ジャーナル フリー
    11-Amino-
    6
    ,
    6
    a,
    7
    ,
    8
    ,
    9
    , 10, 10a, 11-octahydrodibebenzo[
    b
    ,
    e
    ]thiepines (
    6
    a-
    d
    ) and -oxepines (
    7
    a-
    d
    ) were synthesized by the Leuckart reaction of
    6
    ,
    6
    a,
    7
    ,
    8
    ,
    9
    , 10, 10a, 11-octahydro-11-oxodibenzo[
    b
    ,
    e
    ]thiepines (1a,
    b
    )and -oxepines (
    2
    a,
    b
    ) followed by hydrolysis of the reaction products 4a-
    d
    and
    5
    a-
    d
    , respectively. The four diastereomers, cis(
    6
    a-H, 10a-H)-cis(10a-H, 11-H)
    6
    a and
    7
    a, cis(
    6
    a-H, 10a-H)-trans(10a-H, 11-H)
    6
    b
    and
    7
    b
    , trans(
    6
    a-H, 10a-H)-trans(10a-H, 11a-H)
    6
    c and
    7
    c, and trans(
    6
    a-H, 10a-H)-cis(10a-H, 11-H)
    6
    d
    and
    7
    d
    , were isolated and their configurations and conformations were elucidated by chemical methods together with 1H-nuclear magnetic resonance spectroscopic and X-ray crystallographic analyses.
  • 佐藤 敬之輔
    デザイン学研究
    1970年 1970 巻 11 号 45-55
    発行日: 1970/03/30
    公開日: 2017/07/25
    ジャーナル フリー
    [1] The purpose of this reserch is to make clear what type of design can give good effects to win the high readership score. At the begining I had to know what factors decide the readership score, and how to change the quality of the desing into numerical value. I have used the method of multi-dimentional analysis with the help of a computer, and got the estimation formula, with
    7
    kinds of factors, as follows ; A^^〜=
    B
    +C+
    D
    +K+aE+bF+cG. A^^〜=estimated values of the readership score. 1)
    B
    , C,
    D
    , K : these four factors are given as category values (so we call them); each factor is classified into several categories.
    B
    =week day, classified into
    7
    categories. C=pages of a newspaper, which are characterized by the kinds of articles, news, and the other reading matters, classified into
    22
    categories.
    D
    =kinds of goods and trades of the advertizement, classified into 14 catedories. K=constants, given to each 13 surveys.
    2
    )
    E
    ,
    F
    , G : these factors are given as numerical values. G=area of advertizement, measured by the unit of column in the whole page length, being classified into
    6
    kinds of area (
    2
    .
    5
    ,
    3
    .
    5
    ,
    5
    ,
    7
    , 10, 15) and 15 column means a whole page, about
    2
    ,000cm^
    2
    .
    E
    ,
    F
    are the marks obtained in the design of advertizements.
    E
    =sum of the marks obtained in each design element on the advertizement.
    F
    =the marks obtained on the whole effect of the design.
    3
    ) a,
    b
    , c : coefficients Using the above formula with the category values and the coefficients, we can obtain the naked design effect from the actual value A of readership score: aE+bF=A-(
    B
    +C+
    D
    +K+cG). In this research, I used 1,829 data of readership score from 1960 to 1968, being obtained by 13 survevs, spring and autumn twice a year. The sample of size each survey was
    3
    ,541,
    2
    ,251, or 200 in the other 11 surveys. Multiple correlation coefficient between the estimated value A^^〜 and the actual value A is
    0
    .951. The table
    2
    ^* shows the contribution indexes of each factor by
    3
    kinds of expression-(1) Range : the absolute difference between the maximum and the minimum category values, (
    2
    ) Standard deviations of the category values, (
    3
    ) Partial correlation coefficient : the relationship between the actual values A and each factors. *see the table
    2
    in the thesis in Japanese. [
    2
    ] The important point was in the determination of the values of
    E
    ,
    F
    .
    E
    is the sum of the marks obtained in each design element, classified into four kinds :
    E
    =
    E
    _1+
    E
    _
    2
    +
    E
    _
    3
    +
    E
    _4. design elements [table]
    E
    _1,
    E
    _
    2
    ,
    E
    _
    3
    ,
    E
    _4, these values have the
    5
    grades, as
    0
    , 1,
    2
    ,
    3
    , 4 and
    0
    is given to the design that has no attractive effect or no applicable element. And
    E
    obtain the marks of
    0
    to
    9
    grades as the sum of them. The values of
    F
    have also
    5
    grades,
    0
    to 4. The principles to determine the values of
    E
    ,
    F
    are as follows : a) The marks obtained of
    E
    ,
    F
    must be the relative values among the each survey, and at the same time, they must have constancy within the same survey-the same elements of design must win the same marks obtained.
    b
    ) They must be determined as to win the highest multiple correlation coefficient, when they are put into the estimation formula. c) They must be reasonable. In order to justify them, we must carry many researches on the actual condition. The frequency of accurence of each grade of
    E
    ,
    F
    values, as the table
    5
    -4, and
    5
    -
    5
    in the thesis in Japanese.
  • 藤井 澄三, 斎藤 徹, 木津 京子, 林原 央美, 熊澤 幸成, 中嶋 悟視, 藤澤 哲則
    Chemical and Pharmaceutical Bulletin
    1991年 39 巻 2 号 301-308
    発行日: 1991/02/25
    公開日: 2008/03/31
    ジャーナル フリー
    A detailed account is given of the syntheses of
    9
    -alkyl-
    2
    -deuterioadenines (
    5
    b
    -
    d
    ), adenosine-
    2
    -
    d
    (
    5
    e
    ), and
    2
    '-deoxyadenosine-
    2
    -
    d
    (
    5
    f
    ) from the
    9
    -substituted adenines 1
    b
    -
    f
    through cyclization of the aminoimidazolecarbox-amidine salts
    9
    or the corresponding free bases
    8
    with formic-
    d
    acid-
    d
    or 1-(formyl-
    d
    )-
    2
    (1H)-pyridone. Glycosidic hydrolysis of
    5
    e
    with boiling
    0
    .
    5
    N aqueous HCl afforded adenine-
    2
    -
    d
    (
    5
    a) in 77% yield. Peracid oxidation of
    5
    a-
    e
    produced the corresponding 1-N-oxides (12a-
    e
    ) in fair yields. Methylation of
    9
    -methyl- (12
    b
    ) and
    9
    -benzyladenine-
    2
    -
    d
    1-oxide (12
    d
    ) and adenosine-
    2
    -
    d
    1-oxide (12
    e
    ) with MeI in
    AcNMe2
    gave the corresponding 1-methoxy derivatives (13
    b
    ,
    d
    ,
    e
    ) in good yields. Dimroth rearrangements of 13
    b
    , 13
    d
    , and 13
    e
    via the free bases 14
    b
    , 14
    d
    , and 14
    e
    furnished the
    N6
    -methoxy isomers 15
    b
    , 15
    d
    , and 15
    e
    , but their isotopic purities were unsatisfactory. Unambiguous assignments of the purine-ring proton signals in the proton nuclear magnetic resonance spectra of the unlabeled adenines (1a-
    f
    ,
    2
    a-
    e
    ,
    3
    b
    ,
    d
    , and 10
    e
    ) have been made by comparison with those of the labeled species (
    5
    a-
    f
    , 12a-
    e
    , 13
    b
    ,
    d
    , and 14
    e
    ).
  • 小林 優, 家坂 貴子, 中野 江身子, 平山 耕一郎
    天然有機化合物討論会講演要旨集
    1989年 31 巻 71/P2-1
    発行日: 1989/09/17
    公開日: 2017/08/18
    会議録・要旨集 フリー
    Six new cembranoids sarcophytol P (
    3
    ), R (4), S (
    5
    ), K (
    8
    ),
    F
    (11), and T (13) were isolated from the soft coral Sarcophyton glaucum. Sarcophytol P (
    3
    ) was shown to be the 20-hydroxy derivative of the major component sarcophytol A (1), and afforded the cyclization product
    6
    in CHCl_
    3
    at room temperature, in a same way as in 1. Sarcophytols R (4) and S (
    5
    ) were correlated to 1, by conversion of its
    7
    R,
    8
    R and
    7
    S,
    8
    S epoxide derivatives. Sarcophytol K(
    8
    ) was a 13, 14-dihydroxycembranoid having a 1
    E
    ,
    3
    Z-diene moiety. The absolute configuration of
    8
    and its 1Z,
    3
    E
    - and 1Z,
    3
    Z-isomers sarcophytol
    B
    (
    2
    ) and J (10) were determined by circular dichroism study of their bis-p-dimethylaminobenzoate derivatives. Sarcophytols
    F
    (11) and T (13) were 1
    E
    - and 1
    E
    ,
    3
    Z-isomers of 1. Compound 11 showed characteristic broadening of the ^1H-NMR chemical shifts, due to the restricted conformational interconversion. Using the three cembranoids sarcophytols
    F
    (11, 1
    E
    ,
    3
    E
    ), N (15, 1Z,
    3
    Z) and T (13,1
    E
    ,
    3
    Z), spontaneous autoxidation-cyclization, in CHCl_
    3
    ,was examined, in order to compare the stereochemical course of the reaction with that of 1 (1Z,
    3
    E
    ), which affords trans-fused bicyclo[
    9
    .
    3
    .
    0
    ]tetradecene systems. The 1
    E
    ,
    3
    Z-isomer 13 gave the same cyclization product 18, as in the reaction of 1, even though it is isomeric at C-1,
    3
    . The 1Z,
    3
    Z isomer 15 gave 19, in consequence of the reversed geometry at C-
    3
    of 15. The 1
    E
    ,
    3
    E
    -isomer (11) gave the bicyclic product
    22
    , having an antipodal fusion as compared with 19. This was confirmed by PCC oxidation of 19 and
    22
    , giving enantiomeric ketones 23 and 24 respectively. The 1(14)-epoxide 26 was shown to be the immediate precursor of
    22
    , and acounted for the inversion of the geometry at C-1 of the cyclization product. Compound 26 is isomeric with the epoxide 17 derived from 1. The epoxide 17 is the postulated precursor in the conversion of 13 to 18. It is noteworthy that the mode of antipodal fusion of the cyclopentane rings, in 18 and
    22
    , was controlled by the chirality of the epoxy rings. The C-14 hydroxyl group participates in the transannular cyclization, but was found not to be the requisite functional group for the reaction. Similar treatment of cembrene C (30), the parent hydrocarbon of 1, also reacted in CHCl_
    3
    giving the bicyclic product 32.
  • WILSON H. TANG, TIMOTHY
    D
    . STARK, MAURICIO ANGULO
    地盤工学会論文報告集
    1999年 39 巻 5 号 73-80
    発行日: 1999/10/15
    公開日: 2008/02/29
    ジャーナル フリー
    The advantages and disadvantages of using a back analysis of slope failures to evaluate soil shear strength are discussed. A methodology is presented herein that allows the implied level of reliability associated with soil shear strength parameters back calculated from slope failures to be estimated. A reliability approach is also used to estimate the probability of failure for a given limit equilibrium slope stability method, design factor of safety, and combination of back calculated Mohr-Coulomb shear strength parameters, c' and φ'. The methodology is illustrated using 39 landslides in the Orinda Formation in the San Francisco Bay area. The impact of additional case histories in the same geologic setting, i.
    e
    ., a larger data set, on the required design factor of safety for a given probability of failure is also investigated.
  • Hin-chung Wong, Chia-Yun Ho, Li-Ping Kuo, Tien-Kuei Wang, Chi-Lung Lee, Daniel Yang-Chih Shih
    MICROBIOLOGY and IMMUNOLOGY
    1999年 43 巻 7 号 631-636
    発行日: 1999年
    公開日: 2008/03/17
    ジャーナル フリー
    Vibrio parahaemolyticus is a prevalent food-borne pathogen in Taiwan, Japan and other Asian countries. This work presents a novel ribotyping method for the molecular epidemiological examination of this pathogen. Genomic DNA was fragmented by HindIII digestion and hybridized with cDNA probe for Escherichia coli 16S and 23S RNA genes. A total of 121 isolates obtained from outbreaks during 1992 and 1994 in Taiwan were characterized by this ribotyping method. Four to seventeen restricted fragments were visualized in these isolates. After hierarchical cluster analysis, these isolates were grouped into thirty different ribotypes. In addition, A
    3
    , A
    7
    ,
    E
    3
    and
    F
    1 were the major ribotypes, consisting of
    22
    .
    3
    , 13.
    2
    ,
    9
    .1, and
    8
    .
    3
    % of the isolates, respectively. A,
    E
    ,
    F
    , G and
    B
    were the major groups, consisting of 46.
    2
    , 14.
    0
    ,
    9
    .1,
    6
    .
    7
    , and
    6
    .
    7
    % of the isolates, respectively. The discriminatory ability of this ribotyping method, as determined by Simpson's index of diversity, was
    0
    .93, which closely resembled that of a previously reported pulsed-field gel electrophoresis method.
  • 木原 勝, 大西 邦義, VANGVERAVONG Suwanna, 小林 茂
    Chemical and Pharmaceutical Bulletin
    1989年 37 巻 4 号 870-876
    発行日: 1989/04/25
    公開日: 2008/03/31
    ジャーナル フリー
    8
    -Hydroxy-
    5
    ,
    6
    ,
    7
    ,
    8
    -tetrahydrodibenz[c,
    e
    ]azocines 4
    b
    , c and their methoxy and methylenedioxy derivatives
    7
    a-c and
    8
    a-c were prepared by cyclization of O-protected 1-phenyl-
    2
    -aminoethanols
    6
    b
    , c,
    9
    a-c and 10a-c with zerovalent nickel, followed by hydrolysis of the resulting O-protected azocines 4
    d
    ,
    e
    ,
    7
    d
    -
    f
    and
    8
    d
    -
    f
    , respectively. The half-tub conformation of the tetrahydroazocine ring of these
    8
    -hydroxydibenz[c,
    e
    ]azocines and the quasi-equatorial configuration of the
    8
    -hydroxy group were supported by the proton nuclear magnetic resonance spectra.
  • EMIL BUCHTA, Dieter Kiessling
    International Symposium on the Chemistry of Natural Products
    1964年 1964 巻 E-8-3
    発行日: 1964/04/12
    公開日: 2017/08/18
    会議録・要旨集 フリー
  • 金田 義宏, 加茂前 秀夫, 百目鬼 郁男, 尹 漢武, 中原 達夫
    家畜繁殖学雑誌
    1978年 24 巻 4 号 169-173
    発行日: 1978/12/05
    公開日: 2008/05/15
    ジャーナル フリー
    放牧牛において,prostaglandin
    F
    (
    PGF
    )とestradiol benzoate(
    E2B
    )の同時筋肉注射による発情同期化効果及び同期化された発情期における受胎性にっいて検討し,次の成績を得た。
    1.放牧牛31頭(ホルスタイン種未経産牛)において,黄体期に
    PGF15mg
    を筋肉注射(A群15頭)あるいはこれと同時に
    E2BO
    .
    5
    mgを筋肉注射(
    B
    群16頭)した結果,処置後31~
    96
    時間に発情が発現したものはA群では13頭(86.
    7
    %),
    B
    群では15頭(93.
    8
    %)であり,両群の間には大差がなかった。しかし,発情はA群では処置後37~84時間に13頭 (86.
    7
    %),
    B
    群では31~60時間に14頭(87.
    5
    %)に集中して発現し,
    E2B
    の併用によって発情発現までの時間は短縮した。
    2
    .排卵は,A群では処置後73~120時間に13頭(86.
    7
    %),
    B
    群では61~
    96
    時間に14頭(87.
    5
    %)に起こり,
    E2B
    の併用によって排卵の時期は処置後早期に,かつ短い時間帯に集中した。
    3
    .同期化された発情期に授精したA群の13頭中
    7
    頭(53.
    9
    %),
    B
    群の16頭中
    9
    頭(56.
    3
    %)がそれぞれ受胎し,受胎率において両群の間に差異はなかった。
    4.以上の成績から,
    PGF
    E2B
    を同時に併用筋肉注射することは,発情及び排卵の同期化に効果的であることを認めたが,この処置によって同期化された発情期の受胎性については,さらに多数例について検討する必要がある。
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