Thirty-six patients (19 males, 17 females: atypical schizophrenia; , typical schizophrenia; , depression; 11, neurosis and other psychiatric disorders; ) were operated on according to orbitoventromedial undercutting by Hirose. In all cases, the Rorschach test was carried out and daily behaviors were studied. Thirty-one scales of the test were subjected to multivariate analysis whereas the behaviors were evaluated according to the following criteria, i.., A: recovered or symptom free, : markedly improved, : moderately improved, : slightly improved and : not improved. The following results were obtained.
1) The evaluation of behaviors is as follows. A: 12 cases, : , : , : , : none.
) It was found that scores of +106% and R+106% scales were significantly higher after the operation than before; that correlation coefficients between the scores before and after the operation were considerably high.
) Factor analysis followed by varimax rotation was carried out. Six factors were extracted, i.., (1) sensitivity to emotional stimuli, () ego-strength, () obsessional rigidity, (4) reaction time, () anxiety and tension and () empathy. It was revealed that was high in atypical schizophrenia, depression and neurosis, and that and were significantly different in terms of the factor scores among the four groups A, , and ; was highest in A, and lowest in regardless of whether it was before or after the operation. showed high scores in both A and , and low in .
4) Multiple discriminant analysis was applied to the data of the Rorschach test before the operation, by classifying 36 subjects into the four groups A, , and . As a result, high rates of correct diagnosis were obtained, i.., 100% for A, 78% for , 56% for and 100% for . When the groups and were combined into one group (+) the highest percentage (100%) was seen in A, followed by (89%) and + group (87%). When the groups A and were combined into one group (A+), the percentages of correct diagnosis were 81% for A+, and % for +.
In conclusion, it can be said that scales of the Rorschach test have been proved to be valid for predicting mental and physical states after the orbito-ventromedial undercutting.

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The advantages and disadvantages of using a back analysis of slope failures to evaluate soil shear strength are discussed. A methodology is presented herein that allows the implied level of reliability associated with soil shear strength parameters back calculated from slope failures to be estimated. A reliability approach is also used to estimate the probability of failure for a given limit equilibrium slope stability method, design factor of safety, and combination of back calculated Mohr-Coulomb shear strength parameters, ' and φ'. The methodology is illustrated using 39 landslides in the Orinda Formation in the San Francisco Bay area. The impact of additional case histories in the same geologic setting, i.., a larger data set, on the required design factor of safety for a given probability of failure is also investigated.

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The modulns of longitudinal elasticity and their temperature dependence in commercial aluminum cast alloys were measured in the temperature range from room temperature (20°) to 250° by the resonant frequency method. The results obtained are as follows:
The modulus of longitudinal elasticity tended to decrease weakly and linearly (the tangent of its decrease, m = (-.4--.) × 10²kg//°) with the rise of temperature. Within the range of the experiments, aluminum cast alloys were divided into groups, the lst group materials having large moduli of elasticity at room temperature (i. ., = (7.15-7.25) × 10⁵kg/) were A-T, A-, 4A-, 4A-T4, 4-, 4-T4, A-, A-T4, etc., the nd group materials having intermediate moduli (i. ., = (.85-.98) × 10⁵kg/) were 4-, 4-T, 4-T, 4-, 4-T, 7A-, etc. and the rd group materials showing considerably smaller moduli (i. ., = (.58-.65) × 10⁵kg/) were 1A-, 1A-T, A-, etc. However, there were some differences between the moduli in this experiments and the moduli in the other data books, and these were considered due to the difference of the measurement principles and of hypotheses or assumptions involved in these principles, so it is suggested that the moduli of elasticity should be reported with indication of the measuring method.

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All the birds examined were also associated with bone dysplasia (art alczaormal develop-ment of bone tissue) in the diaphyseal cortex of the leg bones, especially of bones affectedwith dyschondroplasia. This result is very significant in order to clarifyz tlais disease entity.1970:J14, k -1 } 7 ) 7, M77 ) i? ht /, ( K ) 7 ( # L", MB @ (7) t, If!TB& U ", Jff Dyschondroplasia (1*t%7fi!dW) ().g:#[!:.fLlt! K?o, [1: (7)M;tC, rff.?U/:cD, =1lC#li*H(DX15RI!!& t, r, ccl)Efff7flr.#.??t"ut:.?T<.1.?l??/?t:>"A??1!? > >?TMOll?, lI]%G (-srRM) -ts;;.*BI) *M[t fL 54 t:.;*.{1*I[l?(), t@Yllll*fJ?H@(7) %?Jfipj@ (Dyschondroplasia) p, }, (, 1lTi{-X, WIKIM itt{= t "tl%tff{tO 1111IH(-UP!z U-ii) >ES- -)%Wi*fd?1J*[lEj: >11"iifI".*"H*Tl*&Z") #)/?-"k l - vich ) J&it(VhiO"= >If-ffi"!1lYl*I4")Ji/l![40111!>*!)<Y14M)?A"!>CL(Il], k7.ClT"ltTt*flB1? & $4U [-" U" L % w, Zl1*.IlBl tI1J, FA(y L-x") LVfAK t: >llltPJ4IiI " } ) t- ! Al j: >kP11liR, &ffl(NWi Z lk(#L" Ct ?!4M"- fL#, -()%.IWMd1.XI1*I1EPW(tit ff1lR)

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Two new partially saturated tricyclic ring systems, , a, 7, , , 10, 10a, 11-octahydro-11-oxodibenz [, ] oxepins (a and ), and -thiepins (4a and 4) were synthesized. Compounds 4a and 4 were desulfurized to give a pair of isomeric -methylbenzoylcyclohexanes (10a and 10). Deuterated 4a and 4 (11a and 11) were prepared starting from butadiene- (12). The stereochemical features of a (trans), (cis), 4a (trans) and 4 (cis) are compared with those of 10a, 10, 11a and 11 on the basis of proton nuclear magnetic resonance data.

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Natural sedimentary clays exhibit ageing effects on their behaviour when subjected to both consolidation and shearing. Attempts to characterising the in-situ 'structure'of soft marine clays have been made in case studies performed in Ariake (Japan) and in Bangkok (Thailand), each showing a typical profile of aged clay-structure with depth reflecting its site-specific geological consolidation history. In each site, profiles of Atterberg limits, natural water content, overconsolidation ratio (OCR), quasi-elastic shear modulus G_max and the undrained shear strength c_u with depth were attained from various laboratory tests, together with the a comparable profile of quasi-elastic shear modulus from insitu seismic survey G_f. Quantitative assessment of the aged clay-structure was made by using two different measures, metastability index MI (G) and the soil constant reflecting structure S (Jamiolkowski et al., 1994). The profiles of MI (G) and the S-value with depth were both determined based on the corresponding G_max behaviour of the reconstituted sample. "Disturbance"of laboratory samples retrieved by using two different samplers (i.., Laval and Japanese thin-walled samplers) with two different sampling techniques (i.., pre-boring and displacement methods) was discussed. A new approach to estimate c_u"in the ground", termed by the authors the MILK (Metastability Index coupled with Laboratory K_o test) method, is proposed. A trial of the MILK-method is demonstrated in soft Bangkok clay, the texture of which is similar to "soft cheese".

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カンキツ主要12種を用いて染色体のクロモマイシン (CMA) 染色を行った．染色体は CMA(+) バンドの有無および位置から 7 種類に区分できた．すなわち，CMA(+) を A: 両端および動原体近傍に有する，: 一方の端部と動原体近傍に有する，: 両端に有する，: 一方の端部に有する，: CMA(+) がない，: 動原体近傍に有する，Dst: 付随染色体を有する 型，である．各種はこれらのうち ～ 種類の染色体を有し，独自の CMA バンドパターンを示した．

C

. medica では + + ，

C

. limon では 1 + 1 + + ，

C

. aurantifolia では + + 7，

C

. aurantium では 1A + 1 + 1 + 7 + ，

C

. sinensis では + + 7 + 7，

C

. maxima では A + + 4 + ，

C

. paradisi では A + + + 7，

C

. ichangensis では + + 12 + ，

C

. latipes では A + + + ，

C

. micrantha では 1 + 11 + 4 + Dst，

C

. macroptera では + 1 + 11 + + 1，

C

. hystrix では + 1 + + + + 1Dst であった．

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Acetylation of 4-(O-acetyl-β--glycopyranosylamino)--oxo-pyrimidines (a, , ) with /pyridine at 80° gave the -acetoxy derivatives a, , . Although these were also obtained by treatment with /, prolonged reactions of a-, - gave the -acetyl derivatives 4a-, -. The Vilsmeier reaction of -g produced the -formyl derivatives -g, whereas a gave the uracil derivative under similar conditions.

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11-Amino-, a, 7, , , 10, 10a, 11-octahydrodibebenzo[, ]thiepines (a-) and -oxepines (7a-) were synthesized by the Leuckart reaction of , a, 7, , , 10, 10a, 11-octahydro-11-oxodibenzo[, ]thiepines (1a, )and -oxepines (a, ) followed by hydrolysis of the reaction products 4a- and a-, respectively. The four diastereomers, cis(a-H, 10a-H)-cis(10a-H, 11-H) a and 7a, cis(a-H, 10a-H)-trans(10a-H, 11-H) and 7, trans(a-H, 10a-H)-trans(10a-H, 11a-H) and 7, and trans(a-H, 10a-H)-cis(10a-H, 11-H) and 7, were isolated and their configurations and conformations were elucidated by chemical methods together with ¹H-nuclear magnetic resonance spectroscopic and X-ray crystallographic analyses.

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The Beckmann rearrangement of aliphatic ketone oximes, R(CHs)=NOH (R=Et (1); n-Pr (); iso-Pr (); iso-Bu (4)), with polyphosphoric acid (PPA), polyphosphate ester (PPE), and ester of phosphoric acid ( P- R) was carried out and migratory ratios ((a)/() in eq. (1)) were determined, The results are shown in Fig.1, , and , respectively.
In Fig.1 and , the migratory ratios decrease with reaction time and nearly approach to the ratios of anti-alkyl form/syn-alkylform in benzene(A1) or DMSO(A)except for () (See Table 1). From this fact, it has been found that PPA and PPE are inactive for isomerization of the oximes andanti-alkyl oximes rearrange faster than syn-alkyl ones. ln the case of (), migratery ratios are smaller than Ai or A. As acetonitrile is detected by GLC, it is presumed that fission has been occurred simultaneously with rearrangement in anti-alkyl oxime (eq. ()). In the case of P- R, all modes of the reaction arethe same as in above, except that the rate of fission is tnuch faster than that in PPA and PPE.
The reaction of anti-alkyl ketone oximes having a bulky grouphas been greatly influenced by the use of sterically demanding catalysts such asPPA, PPE, and P- R.

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A sample of [

3H

] tobrarnycin (

5

, 000 Ci/Mole) has been synthetized and incubated with
the bacterial ribosome and its subunits. The results obtained show that this antibiotic has
two types of binding sites. The primary one is probably responsible for the inhibition of
protein synthesis whereas the secondary one is probably related to the misreading and reading
tiirough of the messenger RNA.

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This study aimed to determine the prevalence of fecal carriage of extended spectrum β-lactamase (ESBL) and/or plasmidic AmpC β-lactamase (pAmpC) producing Escherichia coli among dogs (n=428) in Turkey. Polymerase chain reaction (PCR) and sequencing were used to characterize genes encoding β-lactamase and plasmid mediated quinolone resistance (PMQR). Antimicrobial susceptibility testing and PCRs for virulence genes and phylogenetic groups were also performed. Cefotaxime resistant

. coli isolates were detected in 95 (.%) of the swab samples. Sequencing analysis results showed occurrence of various β-lactamase genes: bla_CTX-M-15 (62), blaTEM-

1b

(42), blaCMY-

2

(

22

), blaCTX-M-

3

(16), bla_CTX-M-1 (15), bla_OXA-1 (

9

) and bla_SHV-12 (

3

) alone or in combination. The most frequently encountered phylogenetic group was group A₁ (35.

8

%), followed by group

D₂

(

22

.1%),

B

1 (15.

8

%),

D₁

(

9

.

5

%), A₀ (7.4%),

B2₂

(

5

.

3

%) and

B2₃

(4.

2

%), respectively. PMQR genes, aac(

6

’)-Ib-cr, qnrS1 and qnrB10 were detected in 25.

3

, 10.

5

and 1.1% of the isolates, respectively. While all isolates were susceptible to imipenem and amikacin, resistance rates to non-β-lactam antibiotics ranged from 20.0% for tobramycin to 56.

8

% for tetracycline. The virulence genes were only detected in 34 (36.

2

%) of the isolates and this isolates carried single or various combination of virulence genes of iucD, papC, papE,

f17a

-A and eaeA. Four isolates were identified as human virulent pandemic CTX-M-15 producing

E

. coli clone O25

b

:ST131/

B

2

. To the best of our knowledge, this is the first study to show fecal carriage of ESBL/pAmpC type β-lactamase producing

E

. coli isolates among dogs in Turkey.

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