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  • 長谷川 親太郎
    The Keio Journal of Medicine
    1992年 41 巻 3 号 146-153
    発行日: 1992年
    公開日: 2009/03/27
    ジャーナル フリー
    Tumor-infiltrating lymphocytes (TIL) were tested for cytotoxicity against autologous tumor cells in a study utilizing a chemically induced cancer ofthe bladder (transitional cell carcinoma),
    BC
    -47, in inbred ACI/N rats. From tumors grown after subcutaneous implantation of
    BC
    -47 in the rats TIL were separated by density gradient centrifugation and incubated in plastic dishes for separation of non-adherent from adherent cells. The non-adherent cells were further fractionated into T and
    B
    cells by the panning method using anti-rat F(ab')2 antibody. The cell fractions were each added to
    BC
    -47 in culture to be assessed for antitumor effect by the crystal violet dye exclusion method and 3H-thymidine incorporation inhibition assay. Peripheral blood mononuclear cells (PBMC) were also tested as described above. TIL expressed significantly higher cytotoxicity against
    BC
    -47 with the mean % cytotoxicity of 56.
    6
    ±
    5
    .
    6
    % and 87.
    5
    ±
    7
    .1% at
    E
    /T ratios of 10:1 and 20:1, respectively, as compared to PBMC(
    9
    .
    9
    ±
    5
    .
    0
    % at
    E
    /T 10:1) (P<
    0
    .001). The adherent cells,
    B
    and T cell fractions showed respective % cytotoxicity of 92.
    4
    ±2.8%, 57.
    9
    ±10.
    6
    % and
    9
    .
    9
    ±
    7
    .8% at an
    E
    /T ratio of 10:1. TIL pretreated with IFN or rIL-2 for 24or 48 hours did not exhibit any noticeably enhanced antitumor activity at an
    E
    /T ratio of
    5
    :1. Prevention of direct contact of
    BC
    -47 cells and TIL by an interposed Millipore membrane (
    0.45μm
    ) resulted in an unequivocal reduction of antitumor effect. This finding clearly indicates that the direct contact with
    BC
    -47cells and TIL is necessary for TIL to manifest their cytotoxicity against the autologous tumor cells, suggesting that TIL exhibit autologous tumor killing activity through cell-mediated cytotoxicity.
  • Joey
    B
    . Tanney, Leonard J. Hutchison
    Mycoscience
    2012年 53 巻 1 号 31-35
    発行日: 2012年
    公開日: 2023/03/31
    ジャーナル オープンアクセス

    The ability of Climacodon septentrionalis to immobilize and kill a mycophagous nematode (Aphelenchoides sp.) in vitro is described for the first time. Two isolates produced droplets (20–45 μm in diameter) that formed at the apices of tall, stalked, and branching secretory cells (700–1,500 μm tall). On 2% modified malt extract agar, nematodes became enveloped in the droplets, which restricted their ability to move and resulted in complete immobilization and death within several hours of contact. The rate of decomposition of the nematodes varied considerably, with most individuals persisting for weeks whereas others were degraded within several days and appeared to be colonized by dense hyphal growth. This study provides the first documentation of a non-agaricoid fungus producing secretory cells that are able to immobilize nematodes.

  • Grover Loening
    日本航空学会誌
    1963年 11 巻 119 号 373-380
    発行日: 1963年
    公開日: 2009/05/25
    ジャーナル フリー
  • 最大地震のマグニチュードcを含む場合
    宇津 徳治
    地震 第2輯
    1978年 31 巻 4 号 367-382
    発行日: 1978/12/25
    公開日: 2010/03/11
    ジャーナル フリー
    In many cases, the log-frequency vs magnitude curves for earthquakes show considerable curvature, though the well-known G-R (Gutenberg-Richter) formula predicts a straight line. To represent such data, two modifications of the G-R formula have been proposed.
    log n(M)=a-bM Mc
    n(M)=
    0
    M>c} (2)
    and log n(M)=a-bM+log(c-M) M<c
    n(M)=
    0
    Mc} (3)
    These are called here the truncated G-R formula and the modified G-R formula, respectively. These equations can be written in the form of probability density function:
    f(x)=
    B
    /1-
    e
    -BCe-Bx Cx
    0
    (
    5
    )
    f(x)=
    B2
    /
    e
    -
    BC
    +
    BC
    -
    1e
    -Bx(C-x) C>x
    0
    (
    6
    )
    where x=M-MS,
    B
    =
    b
    ln 10, C=c-MS, and MS is the lower limit of magnitude above which the data is complete.
    The estimation of
    B
    and C in equation (
    5
    ) by the method of moments was discussed by Okada (1970) and Cosentino et al. (1977). The equations proposed here are
    expC(C-2x)/Cx-x2=C2-2Cx-x2/2x2-x2 (16)
    B
    =(2x-C)/(x2-Cx) (15)
    or x2/x2=2-
    BC
    (
    BC
    +2)/(eBC-1)/1-
    BC
    /(eBC-1) (18)
    Bx=1-
    BC
    /(eBC-1) (19)
    The maximum likelihood method for equation (
    5
    ) yields only one equation (equation (19), Page (1968), Okada (1970)). If we adopt C=Max(xi) as the second equation, the C value is considerably biased. To correct the bias, a correction ΔC which is a function of
    B
    and C is proposed. For this correction we must use some estimated values for
    B
    and C.
    To estimate
    B
    and C in equation (
    6
    ) by the method of moments the following equations are used.
    x2/x2(
    e
    -
    BC
    +
    BC
    -1){
    e
    -
    BC
    (
    B2C2
    +
    4BC
    +
    6
    )+
    2BC
    -
    6
    }/{
    e
    -
    BC
    (
    BC
    +2)+
    BC
    -2}2 (25)
    Bx=
    e
    -
    BC
    (
    BC
    +2)+
    BC
    -2/
    e
    -
    BC
    +
    BC
    -1 (23)
    The maximum likelihood estimates of
    B
    and C in equation (
    6
    ) can be obtained by the equation:
    2-Bx=C/SSi=1 1/C-xi=
    BC
    (1-
    e
    -
    BC
    )/
    e
    -
    BC
    +
    BC
    -1 (27), (29)
    The accuracy of
    B
    and C values determined by the above methods is estimated by Monte Carlo technique for the cases of S=50, 100, 200, 400, and 800 and several values of
    B
    and C. If we adopt the truncated G-R formula, the second method (which uses C=Max(xi)+ΔC) gives more accurate C values, whereas the accuracy of
    B
    values is almost the same as that obtained by the method of moments. If we adopt the modified G-R formula, the maximum likelihood method gives more accurate
    B
    and C values than the method of moments. The η value (η=x2/x2) is a useful index for the deviation of the distribution of data from the G-R formula (for the G-R formula, theoretical value for η is 2). An application of the present methods shows regional variations in
    b
    , c, and η values of shallow earthquakes in Japan.
  • Yukichi Yamaguchi, Jian-zhi Runan(Gen), Teruaki Nagahara
    Journal of the Physical Society of Japan
    1975年 38 巻 4 号 911-916
    発行日: 1975/04/15
    公開日: 2007/06/01
    ジャーナル 認証あり
    The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the 116mIn activity. Directional correlations are also measured for 818–1293 and 1097–1293 keV cascades. The M1-
    E
    2 mixing ratio δ, and the
    E
    0
    -
    E
    2 mixing ratio μk are obtained for 818.
    7
    keV
    22
    +→21+ transition to be δ=1.52
    0.22
    +
    0.26
    , and μk
    6
    .1×10
    4
    respectively. The
    E
    2 branching ratio
    B
    (
    E
    2;
    22
    +
    0g
    +):
    B
    (
    E
    2;
    22
    +→21+):
    B
    (
    E
    2;
    22
    +→01+) is determined to be
    0
    .0158:1.
    0
    :
    5
    .86.
  • 佐藤 敬之輔
    デザイン学研究
    1970年 1970 巻 11 号 45-55
    発行日: 1970/03/30
    公開日: 2017/07/25
    ジャーナル フリー
    [1] The purpose of this reserch is to make clear what type of design can give good effects to win the high readership score. At the begining I had to know what factors decide the readership score, and how to change the quality of the desing into numerical value. I have used the method of multi-dimentional analysis with the help of a computer, and got the estimation formula, with
    7
    kinds of factors, as follows ; A^^〜=
    B
    +C+D+K+
    aE
    +bF+cG. A^^〜=estimated values of the readership score. 1)
    B
    , C, D, K : these four factors are given as category values (so we call them); each factor is classified into several categories.
    B
    =week day, classified into
    7
    categories. C=pages of a newspaper, which are characterized by the kinds of articles, news, and the other reading matters, classified into
    22
    categories. D=kinds of goods and trades of the advertizement, classified into 14 catedories. K=constants, given to each 13 surveys. 2)
    E
    , F, G : these factors are given as numerical values. G=area of advertizement, measured by the unit of column in the whole page length, being classified into
    6
    kinds of area (2.
    5
    , 3.
    5
    ,
    5
    ,
    7
    , 10, 15) and 15 column means a whole page, about 2,000cm^2.
    E
    , F are the marks obtained in the design of advertizements.
    E
    =sum of the marks obtained in each design element on the advertizement. F=the marks obtained on the whole effect of the design. 3) a,
    b
    , c : coefficients Using the above formula with the category values and the coefficients, we can obtain the naked design effect from the actual value A of readership score:
    aE
    +bF=A-(
    B
    +C+D+K+cG). In this research, I used 1,829 data of readership score from 1960 to 1968, being obtained by 13 survevs, spring and autumn twice a year. The sample of size each survey was 3,541, 2,251, or 200 in the other 11 surveys. Multiple correlation coefficient between the estimated value A^^〜 and the actual value A is
    0
    .951. The table 2^* shows the contribution indexes of each factor by 3 kinds of expression-(1) Range : the absolute difference between the maximum and the minimum category values, (2) Standard deviations of the category values, (3) Partial correlation coefficient : the relationship between the actual values A and each factors. *see the table 2 in the thesis in Japanese. [2] The important point was in the determination of the values of
    E
    , F.
    E
    is the sum of the marks obtained in each design element, classified into four kinds :
    E
    =
    E
    _1+
    E
    _2+
    E
    _3+
    E
    _
    4
    . design elements [table]
    E
    _1,
    E
    _2,
    E
    _3,
    E
    _
    4
    , these values have the
    5
    grades, as
    0
    , 1, 2, 3,
    4
    and
    0
    is given to the design that has no attractive effect or no applicable element. And
    E
    obtain the marks of
    0
    to
    9
    grades as the sum of them. The values of F have also
    5
    grades,
    0
    to
    4
    . The principles to determine the values of
    E
    , F are as follows : a) The marks obtained of
    E
    , F must be the relative values among the each survey, and at the same time, they must have constancy within the same survey-the same elements of design must win the same marks obtained.
    b
    ) They must be determined as to win the highest multiple correlation coefficient, when they are put into the estimation formula. c) They must be reasonable. In order to justify them, we must carry many researches on the actual condition. The frequency of accurence of each grade of
    E
    , F values, as the table
    5
    -
    4
    , and
    5
    -
    5
    in the thesis in Japanese.
  • Meral Kurt, Merve Bankoğlu Güngör, Seçil Karakoca Nemli, Bilge Turhan Bal
    Journal of Prosthodontic Research
    2020年 64 巻 2 号 202-209
    発行日: 2020年
    公開日: 2020/07/08
    ジャーナル オープンアクセス

    Purpose: This study aims to evaluate the effect of different glazing methods on translucency parameter (TP), contrast ratio (CR), opalescence parameter (OP), surface roughness (Ra) and topography of the silicate ceramics.

    Methods: Seventy specimens (10 ×10 ×1 mm) were fabricated from lithium disilicate (IPS

    e
    .max CAD, abbreviated as
    E
    ) and zirconia-reinforced lithium silicate (Vita Suprinity, abbreviated as VS) ceramics and divided into
    7
    subgroups (n = 10) according to the polishing and glazing procedures: (1) mechanical polishing before-crystallization (m-
    BC
    ), (2) mechanical polishing after-crystallization (m-AC), (3) glaze powder/liquid after-crystallization (pl-AC), (
    4
    ) glaze-paste before-crystallization (gp-
    BC
    ), (
    5
    ) glaze-paste after-crystallization (gp-AC), (
    6
    ) glaze-spray before-crystallization (gs-
    BC
    ), (
    7
    ) glaze-spray after-crystallization (gs-AC). Color and Ra measurements were performed. CIEL*a*
    b
    * and CIEXYZ parameters were recorded and TP, CR, and OP values were calculated. Data were analyzed using two-way ANOVA and Tukey HSD tests (α =
    0
    .05).

    Results: In

    E
    groups, the highest Ra value was found in gs-AC (1.66 ±
    0
    .14 μm) while the lowest value was found in pl-AC (
    0
    .68 ±
    0
    .08 μm). In VS groups, the highest Ra value was found in gp-
    BC
    (1.64 ±
    0
    .25 μm) while the lowest value was found in m-AC (
    0
    .77 ±
    0
    .06 μm) (p <
    0
    .05). The mean TP value of
    E
    (17.62 ±
    0
    .73) was found to be higher than VS (15.37 ± 1.16). The CR (
    0
    .72±
    0
    .030) and OP (12.06 ±
    0
    .74) values of VS were found higher than CR (
    0
    .57 ±
    0
    .02) and OP (
    6
    .72 ±
    0
    .40) values of
    E
    .

    Conclusions: Zirconia-reinforced silicate ceramics have higher opalescence and lower translucency values than lithium disilicate ceramics. Increase in surface roughness reduces translucency. Glaze powder/liquid after-crystallization is the most effective way to reduce surface roughness of lithium disilicate ceramics while that is mechanical polishing after-crystallization for zirconia-reinforced silicate ceramics.

  • T BAKER, C. RANGACHARYULU
    日本物理学会講演概要集
    1999年 54.2.1 巻 23pSM-6
    発行日: 1999/09/13
    公開日: 2018/03/04
    会議録・要旨集 フリー
  • Keishi Hata, Fuyuki Sugawara, Naganori Ohisa, Saori Takahashi, Kazuyuki Hori
    Biological and Pharmaceutical Bulletin
    2002年 25 巻 8 号 1040-1044
    発行日: 2002年
    公開日: 2002/08/01
    ジャーナル フリー
    We screened the differentiation-inducing activities of 39 mushroom extracts from Akita prefecture, Japan, on the mouse osteoblastic cell line, MC3T3-
    E
    1. Sixteen phosphate buffered saline (PBS), 8 boiled PBS, 14 ethanol and 12 methanol extracts induced alkaline phosphatase (ALP) activities, an indicator of MC3T3-
    E
    1 cell differentiation. The enzyme activities were markedly induced by extracts of Tricholoma auratum, and we isolated the active compound from methanol extracts of this mushroom. Physical data for the isolated active compound were identical to those for (
    22E
    ,24R)-ergosta-
    7
    ,
    22
    -diene-3β,
    ,
    -triol (1). 1 induced ALP activities of MC3T3-
    E
    1 cells and promoted cell proliferation. To investigate the relationships between the chemical structure and differentiation-inducing activity of the compound, ALP-inducing activities of MC3T3-
    E
    1 cells by 1, ergosterol (2), ergocalciferol (3), cholesta-3β,
    ,
    -triol (
    4
    ),
    7
    -dehydrocholesterol (
    5
    ) and cholecalciferol (
    6
    ) were tested. The enzyme activities of MC3T3-
    E
    1 cells were increased 3.
    0
    -fold by 10 μM 1 and 2.
    4
    -fold by 10 μM
    4
    . However, 2, 3,
    5
    and
    6
    did not induce MC3T3-
    E
    1 cell ALP activity at
    0
    .1—10 μM. These results suggested that the OH groups at C-
    5
    and/or C-
    6
    of 1 and
    4
    played an important role in their differentiation-inducing activities on MC3T3-
    E
    1 cells. Furthermore, 1 suppressed induction of MC3T3-
    E
    1 cell apoptosis by serum starvation.
  • A.M. BRITTO, C. SAVVIDOU, M.J. GUNN, J.R. BOOKER
    土質工学会論文報告集
    1992年 32 巻 1 号 13-25
    発行日: 1992/03/15
    公開日: 2008/02/29
    ジャーナル フリー
    One method currently being considered for the disposal of high level radio-active waste is burial in the seabed. When a hot object is buried in soil, the temperature of the soil adjacent to the object is raised and there is transient heat flow away from the object. The rise in the temperature of the soil causes excess pore pressures to be generated and transient pore water diffusion also takes place. A finite element formulation of the coupled heat flow and consolidation problem is presented. The computer implementation of this formulation is found to compare favourably with analytical solutions based on the same physical principles.
  • Masayuki Yoshikawa, Toshio Morikawa, Ning Li, Akifumi Nagatomo, Xian Li, Hisashi Matsuda
    Chemical and Pharmaceutical Bulletin
    2005年 53 巻 12 号 1559-1564
    発行日: 2005年
    公開日: 2005/12/01
    ジャーナル フリー
    The saponin fraction from the seeds of the tea plant [Camellia sinensis (L.) O. KUNTZE (Theaceae)] was found to exhibit potent protective effects on ethanol- and indomethacin-induced gastric mucosal lesions in rats. Five new triterpene saponins, theasaponins
    E3
    (1),
    E4
    (2),
    E5
    (3),
    E6
    (
    4
    ), and
    E7
    (
    5
    ), were isolated together with 11 known saponins from the saponin fraction. The chemical structures of 1—
    5
    were elucidated on the basis of chemical and physicochemical evidence. Among the isolated saponins, theasaponins
    E1
    (
    6
    ),
    E2
    (
    7
    ), and
    E5
    (3) and assamsaponin C (10) showed an inhibitory effect on ethanol-induced gastric mucosal lesions at a dose of
    5
    .
    0
    mg/kg, p.o. and their activities were stronger than that of omeplazole. With regard to the structure–activity relationships of theasaponins, the following structural requirements for a protective effect on ethanol-induced gastric lesions were suggested; 1) the 21- and/or
    22
    -acyl groups are essential for the activity, 2) acetylation of the 16-hydroxyl group reduce the activity.
  • 第2編 慢性骨髄性白血病急性転化時の治療に関する研究
    北川 中行
    岡山医学会雑誌
    1983年 95 巻 9-10 号 913-927
    発行日: 1983/10/30
    公開日: 2009/03/30
    ジャーナル フリー
    To improve the effect of chemotherapy of chronic myelogenous leukemic (CML) in blastic phase, the following clinical analysis were conducted.
    1) The present study consisted of 53 adult patients with CML, who were registered to the 2nd Department of Medicine, Okayama University Hospital and diagnosed as blastic phase between from January 1970 to March 1980. There were 29 males and 24 females, and age ranged from 15 to 77 years (median: 41).
    2) These 53 patients were divided into
    4
    groups. i) Group I-A (
    5
    cases) was diagnosed as blastic crisis (
    BC
    ) with hiatus leukemicus (HL) and initially treated with multicombination chemotherapy such as NCD, DMP or NCDP regimens (N: Neocarzinostatin, C: Cytosine arabinoside, D: Daunorubicin, M;
    6
    -Mercaptopurine, P: Prednisolone). ii) Group I-
    B
    (16 cases) was diagnosed as
    BC
    with HL and initially treated with VP or VPM regimens (V: Vincristine, P: Prednisolone, M:
    6
    -Mercaptopurine). iii) Group II-A (11 cases) was early diagnosed as
    BC
    without HL according to our established criteria, and initially treated with multicombination chemotherapy such as NCMP, DCMP, NDMP, NCDP or NCDVP. and, iv) Group II-
    B
    (21 cases) was early diagnosed as
    BC
    without HL and initially treated with VP, MP, or VPM.
    3) Complete remission (CR) rate of each group was 20.
    0
    % in Group I-A, 56.2% in Group I-
    B
    , 27.3% in Group II-A and 47.
    6
    % in Group II-
    B
    .
    4
    ) Median survival and its surviving ranges after
    BC
    of each group were 3.
    6
    months (1.8-
    4
    .
    5
    ),
    6
    .
    7
    (1.
    0
    -24.2),
    6
    .
    0
    (2.
    6
    -
    22
    .8) and 13.
    0
    (
    4
    .1-43.
    5
    ). Median survival of CR-responders was 3.
    6
    , 10.
    0
    , 8.
    7
    and 17.
    0
    months, respectively.
    5
    ) The rate of one-year survivors of each group was
    0
    %, 31.3%
    9
    .1% and 52.
    4
    %.
    6
    ) In conclusion, the most ideal approach to prolongation of the survival period of CML patients after entering
    BC
    is i) to diagnose
    BC
    as early and accurate as possible, and ii) to treat these patients initially with rather mild regimens such as VP or VPM, instead of aggressive regimens with multicombination drugs.
  • Hiroyuki HIRAOKA, Naoki MORI, Ritsuo NISHIDA, Yasumasa KUWAHARA
    Bioscience, Biotechnology, and Biochemistry
    2001年 65 巻 12 号 2749-2754
    発行日: 2001年
    公開日: 2002/08/30
    ジャーナル フリー
    A mixture of two monoterpenes was obtained as the opisthonotal gland secretion from unidentified Histiogaster sp. A096 (Acari: Acaridae), and their structures were elucidated to be (
    4
    E
    )-dehydrocitrals[(2
    E
    ,
    4
    E
    )- and (2Z,
    4
    E
    )-3,
    7
    -dimethyl-2,
    4
    ,
    6
    -octatrienals] by GC/MS, GC/FT-IR, UV and 1H-NMR spectra. Both isomers of (
    4
    E
    )-dehydrocitral prepared by syntheses in
    4
    steps from 3-methyl-2-butenal with 34.2% yields (based on the ylide) were separated by column chromatography into the (2
    E
    ,
    4
    E
    )- and (2Z,
    4
    E
    )-3,
    7
    -dimethyl-2,
    4
    ,
    6
    -octatrienal. Mass spectra together with GC retention times of the purified natural (
    4
    E
    )-dehydrocitrals were identical with those of synthetic (2
    E
    ,
    4
    E
    )-3,
    7
    -dimethyl-2,
    4
    ,
    6
    -octatrienal and (2Z,
    4
    E
    )-3,
    7
    -dimethyl-2,
    4
    ,
    6
    -octatrienal. The geometry at the 2-C position of both synthetic (
    4
    E
    )-dehydrocitrals was confirmed by NOESY analyses. This is the first identification of (
    4
    E
    )-dehydrocitrals from the animal kingdom.
  • Kiyofumi Ninomiya, Kanae Shibatani, Mayumi Sueyoshi, Saowanee Chaipech, Yutana Pongpiriyadacha, Takao Hayakawa, Osamu Muraoka, Toshio Morikawa
    Chemical and Pharmaceutical Bulletin
    2016年 64 巻 7 号 880-885
    発行日: 2016/07/01
    公開日: 2016/07/01
    ジャーナル フリー HTML
    A methanol extract of the flowers of Mammea siamensis (Calophyllaceae) was found to inhibit enzymatic activity against aromatase (IC50=16.
    5
     µg/mL). From the extract, two new geranylated coumarins, mammeasins C (1) and D (2), were isolated together with seven coumarins: 8-hydroxy-
    5
    -methyl-
    7
    -(3,
    7
    -dimethyl-octa-2,
    6
    -dienyl)-
    9
    -(2-methyl-1-oxobutyl)-
    4
    ,
    5
    -dihydropyrano[
    4
    ,3,2-de]chromen-2-one (
    9
    ), 8-hydroxy-
    5
    -methyl-
    7
    -(3,
    7
    -dimethyl-octa-2,
    6
    -dienyl)-
    9
    -(3-methyl-1-oxobutyl)-
    4
    ,
    5
    -dihydropyrano[
    4
    ,3,2-de]chromen-2-one (10), mammeas A/AA (14), A/AB (15), A/AA cyclo D (18),
    E
    /BA (23), and
    E
    /
    BC
    cyclo D (25). The structures of 1 and 2 were elucidated on the basis of spectroscopic evidence. Among the isolates including 17 previously reported coumarins, 1 (IC50=2.
    7
     µM), 2 (3.
    6
     µM), and mammea
    B
    /AB cyclo D (21, 3.1 µM) showed relatively strong inhibitory activities comparable to the activity of the synthetic nonsteroidal aromatase inhibitor aminoglutethimide (2.
    0
     µM).
  • 石原 研而, 長尾 哲
    土質工学会論文報告集
    1983年 23 巻 1 号 19-37
    発行日: 1983/03/15
    公開日: 2008/02/29
    ジャーナル フリー
    Using the so-called pseudo-static method, a stability analysis was made for the mountain slide that took place at Mitake-iriya village at the time of the Izu-Ohshima-Kinkai earthquake of January 14, 1978. Undisturbed samples of volcanic clay were obtained in blocks from the exposed surface of the deposit identified to have been the sliding surface. The partially saturated clay samples were tested under consolidated undrained conditions using the triaxial test equipment. Dynamic axial stresses with irregular time histories were applied to the specimens in combination with statically sustained axial stresses to determine the soil strength under the conditions simulating in-situ states of stress during the earthquake. The results of the tests were expressed in terms of the Mohr-Coulomb type failure criterion which showed that, while the angle of internal friction remained almost unchanged, the cohesion component in irregular loading increased above values obtained in the static loading. Using the strength parameters thus determined, a pseudo-static analysis was made to check the stability of the soil masses that had actually slid during the 1978 earthquake. The maximum horizontal acceleration required to cause the slide was computed. The computed accelerations were shown to cover a range between 400 and 500 gals which is consistent with the range estimated by other investigators on the basis of overturning of tombstones in the vicinity of the slide area.
  • 香山 滉一郎, 森下 政夫, 張 国鋒
    粉体および粉末冶金
    2006年 53 巻 5 号 419-429
    発行日: 2006年
    公開日: 2006/12/19
    ジャーナル オープンアクセス
    The phase diagrams of the Ni-Mo-
    B
    and Ni-W-
    B
    ternary systems in the region of less than 50mol%
    B
    were constructed by thermodynamic calculation, based on the data obtained by thermodynamic measurement of the related materials. We found three ternary eutectic points and three or two ternary peritecto-eutectic points as follows:
    E1
    :L (1365K, 71.
    5
    mol%Ni-
    6
    .
    0
    mol%Mo-
    22
    .
    5
    mol%
    B
    )=(Ni)+
    Ni3B
    +
    NiMo2B2

    E2
    :L (1355K, 62.
    5
    mol%Ni-2.
    5
    mol%Mo-30.
    5
    mol%
    B
    )=
    Ni3B
    +
    Ni2B
    +
    NiMo2B2

    E3
    :L (1445K, 42.
    0
    mol%Ni-30.
    6
    mol%Mo-10.3mol%
    B
    )=(Ni)+NiMo+
    NiMo2B2

    P1:L (1812K, 34.
    9
    mol%Ni-42.3mol%Mo-
    22
    .8mol%
    B
    )+MoB=
    Mo2B
    +
    NiMo2B2

    P2:L (1633K, 42.3mol%Ni-40.
    4
    mol%Mo-17.3mol%
    B
    )+Mo=
    Mo2B
    +
    NiMo2B2

    P3:L (1812K, 53.
    5
    mol%Ni-33.
    7
    mol%Mo-12.8mol%
    B
    )+Mo=NiMo+
    NiMo2B2

    E1
    :L (1622K, 51.
    0
    mol%Ni-31.
    6
    mol%W-17.
    4
    mol%
    B
    )=(Ni)+W+
    NiW2B2

    E2
    :L (1260K, 71.
    0
    mol%Ni-
    7
    .
    0
    mol%W-
    22
    .
    0
    mol%
    B
    )=(Ni)+
    Ni3B
    +
    NiW2B2

    E3
    :L (1291K, 65.
    4
    mol%Ni-
    4
    .8mol%W-29.8mol%
    B
    )=
    Ni2B
    +
    Ni3B
    +
    NiW2B2

    P1:L (2115K, 23.8mol%Ni-43.1mol%W-33.1mol%
    B
    )+WB=
    W2B
    +
    NiW2B2

    P2:L (1657K, 48.
    9
    mol%Ni-33.1mol%W-18.
    0
    mol%
    B
    )+
    W2B
    =W+
    NiW2B2

    The calculated phase diagrams are expected to be useful for the development of new Ni-based heat-, corrosion- or wear-resistance alloys.
  • Yasuyuki Gono, Manabu Fujioka, Tamotsu Toriyama
    Journal of the Physical Society of Japan
    1970年 29 巻 2 号 255-258
    発行日: 1970/08/05
    公開日: 2007/06/01
    ジャーナル 認証あり
    The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the Tb152 activity. The L-subshell electron lines of the 586.
    7
    keV
    22
    +→21+ transition are separated by the ion-free beta-ray spectrometer. The M1-
    E
    2 mixing ratio, δ2, and the dimensionless ratio X of
    E
    0
    -
    E
    2 mixing of the 586.
    7
    keV transition are obtained to be δ2
    0
    .16 and
    0
    .034≤X
    0
    .038, respectively. The
    E
    2 branching ratio
    B
    (
    E
    2;
    22
    +→
    0g
    +):
    B
    (
    E
    2;
    22
    +→21+):
    B
    (
    E
    2;
    22
    +→01+) is determined to be
    0
    .023 : 1.
    0
    :
    5
    .
    6
    .
  • 松本 樹典, 武井 正孝
    土質工学会論文報告集
    1991年 31 巻 2 号 14-34
    発行日: 1991/06/15
    公開日: 2008/02/29
    ジャーナル フリー
    Stress wave theory is applied to open-ended pipe piles to clarify the effects of soil plug on the behaviour of piles during driving and static loading. Measured field data and various numerical models are reviewed ; methods are presented to calculate wave propagation in both the pile and the soil plug ; modelling is presented which takes into account the interaction between the soil plug and the pile ; also presented is simplified method to estimate the loadsettlement relation of the pipe pile in static loading. By correlating observed and calculated values in two analytical cases, the authors demonstrate that incorporation of the soil plug (modelled as a series of masses and springs) is required to correctly predict pile behaviour during driving and static loading.
  • 豊田 宏
    Journal of the Vacuum Society of Japan
    2017年 60 巻 3 号 81-84
    発行日: 2017年
    公開日: 2017/03/23
    ジャーナル フリー
     We fabricated Ni films on a Polyimide (PI) film and an Acrylonitrile-Butadiene-Styrene (ABS) resin substrate using unbalanced magnetron sputtering assisted by inductively coupled plasma. For the PI film, the effect of ion irradiation was controlled by substrate DC bias VS and magnetic flux density toward the substrate
    BC
    . For the ABS resin substrate, the effect of ion irradiation was controlled by target DC power PT and magnetic flux density toward the substrate
    BC
    . For each substrate, we investigated the effect of ion irradiation on the Ni film structures in detail. The effect of ion irradiation
    E
    was estimated by measured physical quantities with respect to sputtered atom flux, ion flux and ion energy. From x-ray diffraction measurement, the crystallite size t(111) increased with the effect of ion irradiation. Minimum film resistivities of
    9
    .
    0
    ×10
    6
    and 1.
    4
    ×10
    5
    Ωcm were measured for
    BC
    =3 mT and
    E
    =
    0
    .24 on the PI film and
    BC
    =
    5
    mT and
    E
    =
    0
    .98 on the ABS resin substrate, respectively. We conclude that controlling the effect of ion irradiation is effective for high quality Ni film formation on the PI film and the ABS resin substrate.
  • SHENBAGA R. KANIRAJ
    土質工学会論文報告集
    1993年 33 巻 2 号 82-90
    発行日: 1993/06/15
    公開日: 2008/02/29
    ジャーナル フリー
    Based on the recommendations of Berezantzev et al., a new semi-empirical equation for settlement ratio of pile foundations in sand has been derived. The settlement ratios obtained using this equation have been compared with the actual measured values. The comparison indicates that the new equation predicts higher than actual settlement values and is therefore conservative. The new equation is therefore modified in the light of empirical evidence and presented in a generalised form which can be used for square, rectangular, and irregular pile groups. The procedures recommended for the use of the equation in preliminary designs are explained.
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