The world is in the midst of a huge fundamental shift in fibre supply, demand balances, and policy changes. Governments around the world are introducing policy changes which influence the supply demand balance as the politicians' thoughts are uttered. Government agencies and their bureaucrats are imposing changes on industry even before the legislation is passed by the government in question.
This ad hoc change process will continue for a time to come until the countries in question show a tough-mindedness with regard to their land use policies. Policies affecting forest areas such as protection areas, Native land claims, the protection of biodiversity and a true goal of sustainable development ; which addresses the combined issues of cultural, environmental, social and economic matters.
Eventually all of these difficult issues will reach essential closure. Then there will be great new opportunities for investment to meet the growing demand for forest products ; leading to a strengthening competitive position in the more traditional producing areas such as Canada.

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The influence of inhaled Broncasma Berna® on the lower airways was evaluated by histopathological examination. Thirtynine rabbits were divided into groups (A-I). In group A, Broncasma Berna® () solution was administered by ultrasonic nebulization twice a week for weeks starting four weeks after immunization with and Freund's complete adjuvant (CFA). In group , a steroid was inhaled along with in the same schedule as in group A. In group C, .% saline solution (SS) was injected and inhaled. In group , SS was inhaled after immunization with CFA and SS. Group A- animals were sacrificed 24 hours after the last inhalation. Group -H rabbits were sacrificed 1, 2, or 12 weeks after the last inhalation, but otherwise the schedule was the same as in group A. Group I was the control group in which nothing was done for 24 weeks. The groups were compared histologically and immunologically. No change was observed during Ag challenge.
Typical pathological changes were macrophage infiltration and granulomatous proliferation resembling sarcoidosis in the alveoli. The degree of severity was A=>, F, G>>H>C>I. The specific antibody in serum measured by ELISA was significant-ly higher in groups A, , , F, G and H than in I or the SS control groups. The Ab titer in BALF was higher in groups A, and G. The elevated BALF IgG level correlated statistically well with the degree of granulomatous proliferation.

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日本人乳歯の萌出時期および萌出順序を明らかにし，乳歯の萌出に変化が生じているか否かを検討する目的で，全国的に3 か月から3 歳11 か月の小児

,724 名を調査し，以下の結果を得た。

1 ．男児の乳歯萌出は，A が

か月－ か月，A が7 か月－11 か月， が か月－1 歳2 か月， が か月－1 歳3 か月， が1 歳1 か月－1 歳 か月， が1 歳1 か月－1 歳7 か月，C が1 歳2 か月－1 歳 か月，C が1 歳2 か月－1 歳 か月， が1 歳11 か月－2 歳7 か月， が2 歳 か月－2 歳11 か月の順だったが， 間と, , C およびC の間には有意な差は認められなかった。

2 ．女児の乳歯萌出は，A が

か月－ か月，A が7 か月－11 か月， が か月－1 歳1 か月， が か月－1 歳2 か月， が1 歳1 か月－1 歳7 か月， が1 歳1 か月－1 歳7 か月，C が1 歳3 か月－1 歳 か月，C が1 歳 か月－1 歳 か月， が1 歳11 か月－2 歳7 か月， が2 歳1 か月－2 歳10 か月の順だったが，AA 間，AB 間， 間，DD 間，CC 間には有意な差は認められなかった。

3 ．性差は大部分の歯で認めず，C とC の萌出時期にのみ有意な差を認め，いずれも男児が1 か月早く萌出していた。

．前回報告（1988 年）に比べて，男児はA, A, C, の，女児はA と の，萌出時期が有意に早くなっていることを認めた。

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