The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the ^116mIn activity. Directional correlations are also measured for 818–1293 and 1097–1293 keV cascades. The M1- mixing ratio δ, and the 0- mixing ratio μ_k are obtained for 818.7 keV +→2₁⁺ transition to be δ=1.52−

0.22

+0.26, and μ_k≤

6

.1×10⁻⁴ respectively. The

E

2

branching ratio

B

(

E

2

;

2₂

+→0_g⁺):

B

(

E

2

;

2₂

+→2₁⁺):

B

(

E

2

;

2₂

+→0₁⁺) is determined to be 0.0158:1.0:

5

.86.

抄録全体を表示

The gamma-ray spectrum and the conversion-electron spectrum are measured in the decay of the Tb¹⁵² activity. The L-subshell electron lines of the 586.7 keV +→2₁⁺ transition are separated by the ion-free beta-ray spectrometer. The M1- mixing ratio, , and the dimensionless ratio X of 0- mixing of the 586.7 keV transition are obtained to be ≤0.16 and 0.034≤X≤0.038, respectively. The branching ratio (; +→0_g⁺): (; +→2₁⁺): (; +→0₁⁺) is determined to be 0.023 : 1.0 : ..

抄録全体を表示

The phase diagrams of the Ni-Mo- and Ni-W- ternary systems in the region of less than 50mol% were constructed by thermodynamic calculation, based on the data obtained by thermodynamic measurement of the related materials. We found three ternary eutectic points and three or two ternary peritecto-eutectic points as follows:
:L (1365K, 71.mol%Ni-.0mol%Mo-.mol%)=(Ni)++
:L (1355K, 62.mol%Ni-.mol%Mo-30.mol%)=++
:L (1445K, 42.0mol%Ni-30.mol%Mo-10.3mol%)=(Ni)+NiMo+
P₁:L (1812K, 34.mol%Ni-42.3mol%Mo-.8mol%)+MoB=+
:L (1633K, 42.3mol%Ni-40.4mol%Mo-17.3mol%)+Mo=+
P₃:L (1812K, 53.mol%Ni-33.7mol%Mo-12.8mol%)+Mo=NiMo+
:L (1622K, 51.0mol%Ni-31.mol%W-17.4mol%)=(Ni)+W+
:L (1260K, 71.0mol%Ni-7.0mol%W-.0mol%)=(Ni)++
:L (1291K, 65.4mol%Ni-4.8mol%W-29.8mol%)=++
P₁:L (2115K, 23.8mol%Ni-43.1mol%W-33.1mol%)+WB=+
:L (1657K, 48.mol%Ni-33.1mol%W-18.0mol%)+=W+
The calculated phase diagrams are expected to be useful for the development of new Ni-based heat-, corrosion- or wear-resistance alloys.

抄録全体を表示

The possibility of attenuation of microseismic waves due to the presence of an upward folding of the ocean bottom into the liquid is discussed in this paper. The upward folding of the ocean bottom has been idealized by means of an irregularity in the form of a rectangle intruding into the liquid and the evaluation of the displacement component at any point of the solid medium has been carried out in two stages. First, the change in the incident mode of the surface wave due to the presence of the rectangular irregularity has been determined, and second, the subsequent change of the resulting displacement components due to the termination of the liquid layer and the step change in elevation of the solid medium at the continental margin has been discovered. Finally, numerical calculation has been made to determine the attenuation of the microseismic waves of different periods due to the presence of the rectangular irregularity at the ocean bottom.

抄録全体を表示

We observed transients during the isotopic analysis of carbon dioxide, which could not be attributed to mixing processes because of their asymmetry, and to explain these we were led to consider the effects of diffusion on gas flow in the sample line. In particular, we investigated the propagation by diffusion of a concentration anomaly against a steady gas flow. If fractionation of isotopic(or chemical)species at the leak is to cause a change with time of the composition of the gas in the sample reservoir, then the effects of the fractionation must diffuse backwards as far as the gas reservoir.Using a one-dimensional Green's function, we obtained explicit analytical functions for the steady state concentration variation along a connecting tube between the leak and the reservoir, and for the composition variations with time at the leak. It is shown that the isotopic composition in the sample reservoir need not vary with time, even with a fractionating leak, provided that bulk gas velocity in the connecting tube is large enough. It is also shown that the diffusion process in combination with a fractionating leak can lead to the type of transients we observed.

抄録全体を表示

Brassinolide analogues, (R, 23R, 24R)-, 3α, , 23-tetrahydroxy--homo-7-oxa--ergostan--one (24-epibrassinolide) (10) and (S, 23S, 24R)-, 3α, , 23-tetrahydroxy--homo-7-oxa--ergostan--one (), were synthesized from brassicasterol (3a) in five steps and with ca. 20% overall yield. The key steps are the direct formation of (, 24R)-3α, -cyclo--ergost--en--one (4) from brassicasterol mesylate (3), the acid-catalyzed rearrangement of 4 to (, 24R)--ergosta-, -dien--one (), and the Baeyer-Villiger oxidation of the tetrahydroxy -ergostan--ones 7 and 8.

抄録全体を表示

The solubility and supersolubility of L-phenylalanine in aqueous solutions is firstly reported in this work. At temperatures from 273.15 to 343.15 K, both solubility and supersolubility in water generally increase with the temperature, and the average metastable zone width is about 8.3°C. At the temperature of 298.15 K, the solubility remarkably decreases with an increase in the concentration of ethanol, which indicates that ethanol can be used as an antisolvent for the precipitation and crystallization of L-phenylalanine. When sodium chloride is added to the solution, the solubility of L-phenylalanine increases with the concentration of sodium chloride.

抄録全体を表示

CDは成熟細胞上に発現されるリンパ球特異的接着分子である。最近の研究で、CDはイムノグロブリンスーパーファミリーメンバーの構造をしているものの、その機能的特質はシアル酸特異的レクチンの特質を持つことが示された。CDのユニークさは、特異的な結合のシアル酸のみを認識し、α,シアル酸転移酵素によるCD自身のシアル化によって接着分子としての機能を捨て去ることができるという報告によってはっきり示される。白血球特異的ホスホチロシンホスファターゼであるCD45もCDによって認識されるシアロ糖タンパク質であることが発見されたことは、CDがリンパ球活性化の制御に関係する分子かもしれないという興味深い可能性を増すものである。この総説はCD分子とその推測される機能についての私たちの最近の知識を要約したものである。

抄録全体を表示

Monoclonal antibodies (MAbs) specific to the -kDa coat protein (CP) of Broad bean wilt virus (BBWV-) were produced. The -kDa CP of the IA isolate expressed in

E

. coli was used to immunize mice and three independent hybridoma cell lines were screened. In western blot analyses, the MAbs (MAb3-, MAb-12A and MAb-A) reacted to the bacterially expressed -kDa CP of the IA isolate and most BBWV- isolates, but not to some other BBWV- isolates and other plant viruses. In immuno-electron microscopy, MAb3- and MAb-A reacted with BBWV- particles to the 10-

5

dilution.

抄録全体を表示

Two new partially saturated tricyclic ring systems, , a, 7, 8, , 10, 10a, 11-octahydro-11-oxodibenz [, ] oxepins (3a and 3), and -thiepins (4a and 4) were synthesized. Compounds 4a and 4 were desulfurized to give a pair of isomeric -methylbenzoylcyclohexanes (10a and 10). Deuterated 4a and 4 (11a and 11) were prepared starting from butadiene- (12). The stereochemical features of 3a (trans), 3 (cis), 4a (trans) and 4 (cis) are compared with those of 10a, 10, 11a and 11 on the basis of proton nuclear magnetic resonance data.

抄録全体を表示

This study aimed to determine the prevalence of fecal carriage of extended spectrum β-lactamase (ESBL) and/or plasmidic AmpC β-lactamase (pAmpC) producing Escherichia coli among dogs (n=428) in Turkey. Polymerase chain reaction (PCR) and sequencing were used to characterize genes encoding β-lactamase and plasmid mediated quinolone resistance (PMQR). Antimicrobial susceptibility testing and PCRs for virulence genes and phylogenetic groups were also performed. Cefotaxime resistant

. coli isolates were detected in 95 (.%) of the swab samples. Sequencing analysis results showed occurrence of various β-lactamase genes: bla_CTX-M-15 (62), blaTEM-

1b

(42), blaCMY-

2

(

22

), bla_CTX-M-3 (16), bla_CTX-M-1 (15), bla_OXA-1 (

9

) and bla_SHV-12 (3) alone or in combination. The most frequently encountered phylogenetic group was group A₁ (35.8%), followed by group

D₂

(

22

.1%),

B

1 (15.8%), D₁ (

9

.

5

%), A₀ (7.4%),

B2₂

(

5

.3%) and

B2₃

(4.

2

%), respectively. PMQR genes, aac(

6

’)-Ib-cr, qnrS1 and qnrB10 were detected in 25.3, 10.

5

and 1.1% of the isolates, respectively. While all isolates were susceptible to imipenem and amikacin, resistance rates to non-β-lactam antibiotics ranged from 20.0% for tobramycin to 56.8% for tetracycline. The virulence genes were only detected in 34 (36.

2

%) of the isolates and this isolates carried single or various combination of virulence genes of iucD, papC, papE, f17a-A and eaeA. Four isolates were identified as human virulent pandemic CTX-M-15 producing

E

. coli clone O25

b

:ST131/

B

2

. To the best of our knowledge, this is the first study to show fecal carriage of ESBL/pAmpC type β-lactamase producing

E

. coli isolates among dogs in Turkey.

抄録全体を表示

In order to examine the reaction of , 11-dihydrodibenzo [, ] thiepin-11-ones (21) and antimony pentachloride, reaction of various ketones with or HCl- was carried out. Tricyclic ketones (1a-d) gave the corresponding protonation products (a-d) but monocyclic ketones, such as diphenylcyclopropenone (13) and γ-pyrone (19) only formed ketone- adducts (1 : 1) (12, 18) with and protonation products (14, 20) with HCl-. Stereochemical considerations were made on the formation mechanism of these products. Reaction of , 11-dihydrodibenzo [, ] thiepin-11-one (21) with gave the anticipated protonation product () but that of -chloro-, 11-dihydrodibenzo [, ] thiepin-11-one () and resulted in cleavage of the thiepin ring, contrary to expectations, and a compound (23) of undetermined structure was obtained. This compound (23) transited to bis [-(-formylbenzoyl) phenyl] disulfide (24) by hydrolysis.

抄録全体を表示

Melithasterols A-D (1-4), isolated from a gorgoinan coral Melithaea ocracea of Okinawa, were shown to be cholestane-, 24-methyl--dehydrocholestane-, -dehydrocholestane-, and 24-methylenecholestane-derivatives. respectively, having a common 3β, 7α -dihydroxy-α, α-epoxy-Δ^8 steroid nucleus. This was confirmed by direct comparison with the authentic sample prepared by lead tetra-acetate oxydation of cholest--ene- 3β, α, 8α-triol 3-monoacetate. Twelve new polyhydroxysterols were isolated from an Alcyonium sp. (7,8,), and Sclerophytum sp. (14,16,19,20,21,a,23,26,28) soft corals collected off the coasts of the Andaman and Nicobar Islands in the Indian Ocean. All the Sclerophytum sp. soft corals contained 17a or its 25-deacetyl derivative. Compounds 7 to were identified as 24-methylenecholest--ene- 3β, 16β-diol-3-0-α-L fucoside (7) and its 7β-(8) and 7α-hydroxy () derivatives. Compound 14 was shown to be 24S-24-methylcholest--ene-3β,25ξ,26-triol and was correlated to the known compound 15 by α, β-glycolation. Compound 16 was shown to be β, α-isomer of 17, correlating to 17 by PCC oxidation followed by dehydration. Compound 19 was identified with 25-deacetyl derivative of the known compound lobosterol (19a) by hydrolysis of authentic lobosterol. Compounds 20 and 21 were shown to be 7-dehydro-(20) and -dehydro-(21) derivative of 17a and 17, respectively, by comparisons of their spectral data with reference compounds. Compounds a and 23 were 24S-methylcholestane-3β, α 25-triol--one 25-monoacetate (a) and its 25-deacetoxyl derivative (23). Partial PCC oxidation of 17a afforded a. Compounds 26 (andamansterol) and 28 (nicobarsterol) were shown to be gorgost--ene-3β, α. 11α, 21-tetrol and novel secosteroid, 11,21-cyclo--homo-11-oxa-, 11-secoergostane-3β, α, 12ξ-triol--one, respectively, by spectral analyses (H-HCOSY, HMQC, HMBC).

抄録全体を表示