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  • 藤井 弘章, 国政 華菜, 難波 明代, 横溝 隆之, 西村 伸一, 島田 清, 堀 俊男, 西山 竜朗
    地盤工学会論文報告集
    2000年 40 巻 6 号 117-131
    発行日: 2000/12/15
    公開日: 2008/02/29
    ジャーナル フリー
    This study was performed to clarify which factors affected damage to tame-ike (small embankment dams for irrigation) in Hokudan Town as a result of the January 17, 1995 Hyogoken-Nambu earthquake. Factors were assumed to be : Location (
    e
    .g., Distance to Epicenter, etc.), Structure (
    e
    .g., Angle to Nearest Fault, Embankment Volume, etc.), Soil Properties of Embankment, Geology of Dam Site and History (Era of Construction, Repaired, etc.). Multivariate statistical analyses were performed for documentary data (damaged : 181, undamaged : 328). Ordinary statistical analyses were conducted for the data investigated in situ for soil properties of the embankment. The results show that the factors causing damage to dam are : (1) Nearest Fault (Nojima, Mizukoshi and D2), (2) Distance to Nearest Fault (less than 500 m), (3) Distance to Epicenter (approximately
    8
    to 14 km, which almost agrees with the location of seismic intensity 7 JMA), (
    4
    ) Elevation of Dam Site (higher than 100 m), (
    5
    ) Embankment Volume (the greater the volume the more damage was caused), (
    6
    ) Direction of Dam Axis (normal or diagonal to the epicenter or to nearest the fault), (7) Plan View of Dam Axis (3 or
    4
    axes), (
    8
    ) Surface Geology of Dam Site (non-cohesive soil type ground), (
    9
    ) Era of Construction (prior to 1891) and (10) Soil Properties of Embankment (sand, not silty sand or gravel, penetration resistance that is 10% smaller than the undamaged dams).
  • Suguru TAKATSUTO, Kiyomi KOBAYASHI, Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE
    Agricultural and Biological Chemistry
    1988年 52 巻 12 号 3217-3218
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • AKIRA MURAKAMI, AKIHIKO WAKAI, KAZUNORI FUJISAWA
    SOILS AND FOUNDATIONS
    2010年 50 巻 6 号 877-892
    発行日: 2010年
    公開日: 2011/03/04
    ジャーナル フリー
    This paper provides a comprehensive survey of the numerical methods related to geotechnical problems, most of which were reported in papers appearing in Soils and Foundations. The reason why most of the reviewed papers are concentrated in Soils and Foundations is that if we were to include papers appearing in other journals in the field of geotechnical engineering, closely related to numerical methods,
    e
    .g., Computers and Geotechnics, Int. J. Numer. Anal. Meth. Geomech., etc., we would have to deal with almost all the papers in those journals. Firstly, we present a description of the current status of the numerical methods, and then give a brief review of the literature covering several topics in geotechnical applications. The scope of the review is limited, and thus, the authors do not profess to cover the entire range of literature.
  • Özkan ASLANTAŞ, Ebru Şebnem YILMAZ
    Journal of Veterinary Medical Science
    2017年 79 巻 6 号 1024-1030
    発行日: 2017年
    公開日: 2017/06/16
    [早期公開] 公開日: 2017/04/27
    ジャーナル フリー

    This study aimed to determine the prevalence of fecal carriage of extended spectrum β-lactamase (ESBL) and/or plasmidic AmpC β-lactamase (pAmpC) producing Escherichia coli among dogs (n=428) in Turkey. Polymerase chain reaction (PCR) and sequencing were used to characterize genes encoding β-lactamase and plasmid mediated quinolone resistance (PMQR). Antimicrobial susceptibility testing and PCRs for virulence genes and phylogenetic groups were also performed. Cefotaxime resistant

    E
    . coli isolates were detected in
    95
    (
    22
    .2%) of the swab samples. Sequencing analysis results showed occurrence of various β-lactamase genes: blaCTX-M-15 (62), blaTEM-1b (42), blaCMY-2 (
    22
    ), blaCTX-M-3 (16), blaCTX-M-1 (15), blaOXA-1 (
    9
    ) and blaSHV-12 (3) alone or in combination. The most frequently encountered phylogenetic group was group A1 (35.
    8
    %), followed by group D2 (
    22
    .1%), B1 (15.
    8
    %), D1 (
    9
    .
    5
    %),
    A0
    (7.
    4
    %),
    B22
    (
    5
    .3%) and B23 (
    4
    .2%), respectively. PMQR genes, aac(
    6
    ’)-Ib-cr, qnr
    S1 and qnrB10 were detected in 25.3, 10.
    5
    and 1.1% of the isolates, respectively. While all isolates were susceptible to imipenem and amikacin, resistance rates to non-β-lactam antibiotics ranged from 20.
    0
    % for tobramycin to 56.
    8
    % for tetracycline. The virulence genes were only detected in 34 (36.2%) of the isolates and this isolates carried single or various combination of virulence genes of iucD, papC, papE,
    f17a
    -A and eaeA. Four isolates were identified as human virulent pandemic CTX-M-15 producing
    E
    . coli
    clone O25b:ST131/B2. To the best of our knowledge, this is the first study to show fecal carriage of ESBL/pAmpC type β-lactamase producing
    E
    . coli
    isolates among dogs in Turkey.

  • 第1編血清蛋白との結合について
    橋本 孝夫
    CHEMOTHERAPY
    1973年 21 巻 1 号 38-44
    発行日: 1973/01/25
    公開日: 2011/03/08
    ジャーナル フリー
    The binding of penicillin G and other 29 antibiotics to the bovine plasma proteins, a part of the pharmacokinetics of antibiotics, was investigated by the ultrafiltrating technique at
    4
    °C.
    As the rates of the binding, inactivation, recovery and binding activity, following values were obtained in order : 64.
    9
    to
    82
    . 7%, 11. 96 to 56. 85%, 7. 77 to 25. 75% and
    8
    .
    9
    to 34. 11% in penicillin antibiotics;
    0
    to 61.
    4
    %,
    0
    to 10. 66%,
    0
    . 49 to 12.
    8
    % and 14. 91 to 41. 72% in glycoside antibiotics; 91.
    0
    to 99.
    9
    %, 16.
    0
    to 46. 19%, 44.
    98
    to 71. 01% and
    4
    . 33 to 21. 06% in tetracycline antibiotics; 55.
    22
    to 94. 1%,
    5
    . 37 to 57. 36%, 1. 32 to 31.
    5
    % and
    9
    . 66 to 40. 65% in macrolide antibiotics; and 72.
    6
    to
    95
    . 68%, 14. 34 to 51. 85%,
    8
    . 19 to 30. 12%, and 17. 28 to 41. 54% in chloramphenicol antibiotics, respectively.
    Optimum pH of the binding of antibiotics to the plasma proteins was in the range
    5
    .
    0
    to
    8
    .
    0
    , i.
    e
    .
    8
    .
    0
    in penicillin antibiotics,
    5
    .
    0
    in glycoside antibiotics, 7.
    0
    to
    8
    .
    0
    in tetracycline antibiotics,
    6
    .
    0
    to 7.
    0
    in macrolide antibiotics, and 7.
    0
    to
    8
    .
    0
    in chloramphenicol antibiotics, respectively.
  • Ying Jiao, Teruhiko Yoshihara, Akitami Ichihara
    Bioscience, Biotechnology, and Biochemistry
    1995年 59 巻 6 号 1032-1035
    発行日: 1995/06/23
    公開日: 2008/02/08
    ジャーナル フリー
    The syntheses of (S)-13-hydroxy-(2
    E
    ,
    4
    E
    ,
    8
    E
    )-tetradecatrienoic acid (1) and (2
    E
    ,
    4
    E
    ,
    8
    Z-tetradecatrienoic acid (2) were carried out by using the Wittig reaction as the key step. The asymmetric center at C-13 and the double bond between C-
    8
    and C-
    9
    for natural compound 1 were reconfirmed as being of (S) configuration and
    E
    , respectively. The relationship between the structure of the unsaturated hydroxy fatty acids and their inhibitory effect on the growth of lettuce was investigated.
  • 小田切 孝人, 田代 眞人
    ウイルス
    2013年 63 巻 2 号 233-240
    発行日: 2013/12/25
    公開日: 2014/10/31
    ジャーナル フリー
  • CONSTANTINE A. STAMATOPOULOS, ELENI G. VELGAKI, SARADA K. SARMA
    地盤工学会論文報告集
    2000年 40 巻 6 号 61-75
    発行日: 2000/12/15
    公開日: 2008/02/29
    ジャーナル フリー
    The objective of this article is to propose and evaluate a sliding-block model to deal with very large displacements of slopes when a horizontal earthquake is applied. The slip surface consists of two inclinations on which full shear resistance is mobilized. Internal shearing exists along a sub-plane that intersects the angle between the two sub-planes that form the external slip surface. The ratio of the distance moved along the two external sub-planes depends on the inclination of the internal sub-plane. If there is a water table line, undrained conditions are assumed during motion and total stress analysis is performed. The governing equations of motion are formulated, analytical solutions are obtained for some cases, and back-analysis of four well-documented slides is performed.
  • HOE I. LING, DOV LESHCHINSKY
    土質工学会論文報告集
    1995年 35 巻 2 号 85-94
    発行日: 1995/06/15
    公開日: 2008/02/29
    ジャーナル フリー
    This paper is concerned with an extension of a rotational limit equilibrium method for determining the permanent displacements of slopes under seismic excitation. In the proposed procedure, the sliding mass is treated as a rigid rotating body defined by a log spiral trace. Permanent displacements are obtained by double-integration of the equation of motion in a manner similar to Newmark's translational sliding block method. The seismic slope stability analysis is based on the rotational (variational) limit equilibrium approach. This stability analysis was verified with dynamic experimental results obtained from centrifuge model testing. A series of parametric studies was conducted on"unstable"slopes, investigating the effects of soil properties and characteristics of excitation on the magnitude of permanent displacements. The higher the frictional angle, the smaller the permanent displacement of the slope is. Low excitation frequency yields larger slope displacement if the excitation is extended for the same time period of time. The effect of frequency becomes less distinct when a larger value of yield seismic coefficient is used. The proposed procedures produce a rational criterion to evaluate the seismic performance of simple slopes. This criterion is based on permanent displacement limit rather than factor of safety alone.
  • /, 龍岡 文夫, FUMIO TATSUOKA
    地盤工学会論文報告集
    1997年 37 巻 4 号 121-126
    発行日: 1997/12/15
    公開日: 2008/02/29
    ジャーナル フリー
    The design implication of stress-confinement effect of nonwoven geotextile is addressed. The unconfined and confined strengths of a selected needle-punched nonwoven geotextile are used to conduct a comparative design of a granular soil retaining wall based on a limit equilibrium approach. A higher wall may be allowed when considering the confined strength as compared to the unconfined strength. For a selected wall height, confined strength allows for fewer geotextile layers when compared to that designed using unconfined strength. It is recommended that stress-confinement test procedure should be standardized so that confinement effect of some nonwoven geotextiles may be incorporated into an individual wall design procedure.
  • 鹿野 美弘, 櫻井 徹朗, 小松 健一, 山田 浩之, 斉藤 謙一
    Chemical and Pharmaceutical Bulletin
    1990年 38 巻 4 号 1082-1083
    発行日: 1990/04/25
    公開日: 2008/03/31
    ジャーナル フリー
    Two new polyacetylene compounds (
    4
    E
    ,
    6
    E
    , 12
    E
    )-1-acetoxy-3-isovaleryloxytetradeca-
    4
    ,
    6
    , 12-trien-
    8
    , 10-diyn-14-ol (B), and (
    4
    E
    ,
    6
    E
    , 12
    E
    )-1-acetoxy-3-(2-methylbutyryloxy)tetradeca-
    4
    ,
    6
    , 12-trien-
    8
    , 10-diyn-14-ol (C) have been isolated along with (
    4
    E
    ,
    6
    E
    , 12
    E
    )-1-acetoxy-3-senecioyloxytetradeca-
    4
    ,
    6
    , 12-trien-
    8
    , 10-diyn-14-ol (A) from Atractylodes Rhizome (Karabyakujutu). The structures of these compounds were determined on the basis of their spectral data.
  • 榎 明潔, 八木 則男, 矢田部 龍一, 一本 英三郎
    土質工学会論文報告集
    1991年 31 巻 2 号 1-13
    発行日: 1991/06/15
    公開日: 2008/02/29
    ジャーナル フリー
    It has been shown after mathematical and mechanical investigation that Limit Equilibrium Method (LEM) can be considered as a method to obtain the necessary condition of Slip Line Method (SLM), and that the solution can be obtained under the condition that Fs=1 and ∂Fs/∂θ=O, where Fs is the safety factor and θ is the inclination of the plane on which the safety factor is defined. Next, the generalized LEM (GLEM) is proposed, dealing with the following points : (1) Triangular or quadrangular blocks can be treated; (2) Safety factors are defined also on interblock planes; and (3) All types of plastic problems, slope stability, bearing capacity, and earth pressure are identically formulated. Two situations regarding treatment of the moment equilibrium condition are discussed. GLEM is applied to well-known problems. The results agree well with those obtained by theoretical methods. GLEM can be used to obtain the distribution of earth pressure or bearing capacity. GLEM, Iike ordinary LEM, is very effective for the practical problems, but GLEM is more theoretical and it can result in more accurate solutions.
  • George W. Lee
    燃料協会誌
    1973年 52 巻 3 号 171-177
    発行日: 1973/03/20
    公開日: 2010/06/28
    ジャーナル フリー
  • ALI TABESH, HARRY G. POULOS
    地盤工学会論文報告集
    2001年 41 巻 3 号 1-16
    発行日: 2001/06/15
    公開日: 2008/02/29
    ジャーナル フリー
    In the seismic analysis of pile foundations the soil is often assumed to be an elastic material and the pressure at the soil pile interface is not limited during the analysis. This may result in a considerable error, as the computed pressure from an elastic analysis may go well beyond the ultimate lateral pressure of real soil. In fact, significant yielding at the soil-pile interface has been observed during real earthquakes, and also in laboratory tests. The yield zone is usually near the ground surface where the effect of inertial force due to the superstructure is higher. This yielding redefines the pile response, and in general cannot be ignored. In order to examine the effects of soil yielding on the internal pile response during earthquakes an approximate analysis is described in this paper which is an extension of a static method developed by the second author (1982) for the analysis of piles subjected to lateral soil movement. This method is then used to investigate the effects of soil yielding on the internal response of piles through a comparative study in which real earthquakes are used. It is shown that for strong earthquakes and heavily loaded piles the soil yielding may considerably increase the amount of maximum pile moment developed in the pile. A marked difference in the effects of yielding on the pile moment and shear is observed and discussed.
  • ABDALLAHI.HUSEIN MALKAWI, ROBERTY. LIANG
    地盤工学会論文報告集
    1996年 36 巻 3 号 67-74
    発行日: 1996/09/15
    公開日: 2008/02/29
    ジャーナル フリー
    The interaction between a penetrating shaft and the surrounding soil media under impact loading is a frequently encountered phenomenon in geotechnical engineering. Examples of such dynamic soil/shaft interaction would include dynamic pile driving, standard penetration testing (SPT), and dynamic driven rod test. Presented in this paper is a novel approach, based on the principle of dynamic system identification, which enables identification of dynamic soil-pile interaction model parameters. The analytical transfer function, relating the output stress wave forms to the input stress wave forms in the soil/shaft system, is derived using the Laplace and Fourier Transform techniques and the one-dimensional wave propagation theories. A numerical solution algorithm based on a variation of gradient method is coded into a micro-computer based program to solve the frequency-dependent soil-pile interaction parameters (Smith model) : soil damping and soil spring stiffness. To further reduce the amount of computational effort required in the solution of the frequency-dependent dynamic soil properties, it is suggested that the solution be obtained for the first-mode natural frequency of the measured stress waves. The results obtained from this simplified solution algorithm, when compared with both numerical simulations and controlled laboratory tests, are reasonably acceptable. The proposed parameter identification technique offers a viable alternative data interpretation procedure for deducing pertinent Smith model parameters used frequently in pile driving analysis.
  • / 鵜飼 恵三, KEIZO UGAI
    地盤工学会論文報告集
    1998年 38 巻 3 号 201-207
    発行日: 1998/09/15
    公開日: 2008/02/29
    ジャーナル フリー
    A comparative study of the static and dynamic response of a slope is carried out, using the large deformation theory of the updated Lagrangian formulation and the conventional infinitesimal theory. In the static analysis, a strength reduction method proposed by one of the authors is used to evaluate the safety factor of the slope. It is found that by the large deformation theory, the safety factor is larger than that calculated by the infinitesimal theory, and this difference becomes large along with the reduction of elastic modulus. In the dynamic analysis, it is observed that the large deformation theory gives smaller sliding displacement and larger response acceleration than the infinitesimal approach. It is concluded that in many cases the large deformation approach gives more adequate solutions.
  • 小林 優, 家坂 貴子, 中野 江身子, 平山 耕一郎
    天然有機化合物討論会講演要旨集
    1989年 31 巻 71/P2-1
    発行日: 1989/09/17
    公開日: 2017/08/18
    会議録・要旨集 フリー
    Six new cembranoids sarcophytol P (3), R (
    4
    ), S (
    5
    ), K (
    8
    ),
    F
    (11), and T (13) were isolated from the soft coral Sarcophyton glaucum. Sarcophytol P (3) was shown to be the 20-hydroxy derivative of the major component sarcophytol A (1), and afforded the cyclization product
    6
    in CHCl_3 at room temperature, in a same way as in 1. Sarcophytols R (
    4
    ) and S (
    5
    ) were correlated to 1, by conversion of its 7R,
    8
    R and 7S,
    8
    S epoxide derivatives. Sarcophytol K(
    8
    ) was a 13, 14-dihydroxycembranoid having a 1
    E
    ,3Z-diene moiety. The absolute configuration of
    8
    and its 1Z,3
    E
    - and 1Z,3Z-isomers sarcophytol B (2) and J (10) were determined by circular dichroism study of their bis-p-dimethylaminobenzoate derivatives. Sarcophytols
    F
    (11) and T (13) were 1
    E
    - and 1
    E
    ,3Z-isomers of 1. Compound 11 showed characteristic broadening of the ^1H-NMR chemical shifts, due to the restricted conformational interconversion. Using the three cembranoids sarcophytols
    F
    (11, 1
    E
    ,3
    E
    ), N (15, 1Z,3Z) and T (13,1
    E
    ,3Z), spontaneous autoxidation-cyclization, in CHCl_3,was examined, in order to compare the stereochemical course of the reaction with that of 1 (1Z,3
    E
    ), which affords trans-fused bicyclo[
    9
    .3.
    0
    ]tetradecene systems. The 1
    E
    ,3Z-isomer 13 gave the same cyclization product 18, as in the reaction of 1, even though it is isomeric at C-1,3. The 1Z,3Z isomer 15 gave 19, in consequence of the reversed geometry at C-3 of 15. The 1
    E
    ,3
    E
    -isomer (11) gave the bicyclic product
    22
    , having an antipodal fusion as compared with 19. This was confirmed by PCC oxidation of 19 and
    22
    , giving enantiomeric ketones 23 and 24 respectively. The 1(14)-epoxide 26 was shown to be the immediate precursor of
    22
    , and acounted for the inversion of the geometry at C-1 of the cyclization product. Compound 26 is isomeric with the epoxide 17 derived from 1. The epoxide 17 is the postulated precursor in the conversion of 13 to 18. It is noteworthy that the mode of antipodal fusion of the cyclopentane rings, in 18 and
    22
    , was controlled by the chirality of the epoxy rings. The C-14 hydroxyl group participates in the transannular cyclization, but was found not to be the requisite functional group for the reaction. Similar treatment of cembrene C (30), the parent hydrocarbon of 1, also reacted in CHCl_3 giving the bicyclic product 32.
  • 汪 発武, 佐々 恭二, 福岡 浩
    地盤工学会論文報告集
    2000年 40 巻 1 号 35-46
    発行日: 2000/02/15
    公開日: 2008/02/29
    ジャーナル フリー
    By employing an undrained cyclic loading ring-shear apparatus, a series of tests to reproduce the dynamic behavior of the Nikawa landslide induced by the January 17, 1995 Hyogoken-Nambu earthquake, is conducted. The test sample is Osaka-group coarse sandy soil taken from the landslide. The initial stress condition acting on a soil element in the sliding surface is applied to the sample. Based on the seismic records monitored at the JR Takarazuka Station, the input seismic wave is synthesized to reproduce the seismic stress acting on the sliding surface. The test results show that the soil failed due to the dynamic loading of the earthquake. The most important results are the excess pore water pressure generation and the acceleration of shear displacement continuing after the main shock. Combined with the grain crushing at the shear zone and the volume reduction in the drained constant-speed ring-shear test, the mechanism of this landslide is interpreted as, shear displacement causing grain crushing in the shear zone and volume reduction, and then resulting in a localized liquefaction phenomenon, "sliding-surface liquefaction". This geotechnical simulation test provides a reasonable interpretation of this highly mobile landslide.
  • Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE, Kiyomi KOBAYASHI, Suguru TAKATSUTO
    Agricultural and Biological Chemistry
    1988年 52 巻 8 号 2117-2118
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • Cbesseredes HORTS
    Journal of Human Ergology
    1982年 11 巻 Supplement 号 429-440
    発行日: 1982/12/15
    公開日: 2011/02/23
    ジャーナル フリー
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