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全文: 鍼灸治療効果の研究
10件中 1-10の結果を表示しています
  • 鍼刺激後の白血球及びリンパ球亜群への量的・質的影響
    山口 宣夫, 松井 恒二郎, 泉 久子, 宗 愛麗, 荒井 松男, 高田 外司, 多留 淳文
    全日本鍼灸学会雑誌
    2002年 52 巻 1 号 17-19
    発行日: 2002/02/01
    公開日: 2011/03/18
    ジャーナル フリー
  • 佐久眞 正弘, 荒井 松男, 松葉 慎太郎, 山口 宣夫
    サイトメトリーリサーチ
    2010年 20 巻 1 号 41-48
    発行日: 2010/03/25
    公開日: 2017/06/12
    ジャーナル フリー

    We have previously reported that acupuncture may regulate the immune system and activate cellular and humoral immunity. In this study, we examined the effects of acupuncture treatment on lymphocyte subsets, intracellular cytokine production, and the catecholamine levels in human peripheral blood in order to elucidate the relationships between the immune system, the autonomic nervous system, and the endocrine system. We sampled peripheral blood from 10 healthy volunteers(age, 20.6 ± 1.6 years)before and 1 day after acupuncture, at the same time on each day, and determined the total and differential leukocyte counts and the levels of 3 catecholamines (adrenaline, noradrenaline, and dopamine). Further, using flow cytometry, we analyzed the lymphocyte subsets and cells producing the intracellular cytokines interferon(IFN)-γ, interleukin(IL)-4, and IL-1β.

    The leukocyte and granulocyte counts significantly decreased after acupuncture(p < 0.05). The number of CD4 cells also significantly decreased(p < 0.01), whereas that of CD8 cells significantly increased(p < 0.01); the CD56/CD3 natural killer(NK)cell and CD11b cell counts also tended to increase. Moreover, the number of IFN-γ-, IL-4-, and IL-1β-producing cells significantly increased(p < 0.01), and the cell count of IFN-γ-producing cells was the highest. The levels of the 3 catecholamines, in particular adrenaline and noradrenaline, tended to decrease after acupuncture. Thus, acupuncture induced a decrease in the granulocyte counts and adrenaline levels as well as an increase in the number of CD8 and IFN-γ-producing cells. These results indicate that the signals produced from acupuncture treatment are transmitted from the peripheral nerve to the central nervous system; this transmission may suppress the secretion of adrenaline via suppression of the sympathetic nerve, and enhance the activity of IFN-γ-producing CD8 T cells and NK cells.

  • II 鍼刺激後の白血球及びリンパ球亜群に対する質的影響
    宛 文涵, 李 愛麗, 泉 久子, 杉山 清, 河田 奈都子, 荒井 松男, 高田 外司, 多留 淳文, 橋本 英樹, 山口 宣夫
    日本温泉気候物理医学会雑誌
    2002年 65 巻 4 号 207-211
    発行日: 2002年
    公開日: 2010/04/30
    ジャーナル フリー
    We have simultaneously proved that cell populations taking charge of immunity in human peripheral blood can be regulated quantitatively by acupuncture. Now we investigated the effect of acupuncture qualitatively on cytokine production by lymphocyte cells in human peripheral blood.
    The number of IL-1β, IL-4 and IFN-γ containing cells, which are closely associated with macrophage, humoral immunity and cellular immunity respectively, were measured by FACScan. We found a significant increase in IFN-γ containing cells after acupuncture. According to this result together with previous results, the enhancement of CD4+ and CD56+ cell counts, the treatment of acupuncture can promote the activity of cellular immunity as well as NK cell.
  • I. 鍼刺激後の白血球及びリンパ球亜群に対する量的影響
    山口 宣夫, 橋本 英樹, 荒井 松男, 高田 外司, 河田 奈都子, 多留 淳文, 李 愛麗, 泉 久子, 杉山 清
    日本温泉気候物理医学会雑誌
    2002年 65 巻 4 号 199-206
    発行日: 2002年
    公開日: 2010/04/30
    ジャーナル フリー
    To evaluate the effects of acupuncture on the immune system, the leukocyte, monocytes, lymphocyte and lymphocyte surface markers, CD2, CD4, CD8, CD11b, CD16, CD19 and CD56 in the peripheral blood of seventeen healthy volunteers were counted. The leukocyte above CD+ cell counts significantly increased after acupuncture. The results indicate that acupuncture may regulate the immune system and can increase the activity of cellular and humoral immunity and NK cell.
    According to the percentage of lymphocytes or granulocytes, volunteers were divided into two types, those with more than 70% of granulocyte were recognized as G type and those with more than 40% of lymphocyte were divided into L type. Interestingly, before and after the treatment of acupuncture, the number of granulocytes and lymphocytes had a negative relationships. Namely we found an increase in the lymphocytes as well as a decrease in the granulocytes in the G type. On the other hand in the L type, we found an increase in the granulocytes and a decrease in the lymphocytes. Therefore we suggest that acupuncture can enhance the activity that maintains the balance of the immune function.
  • 宮山 忠彦, 安野 富美子, 封木 麻里, 越石 直巳, 吉田 章, 會川 義寛, 坂井 友実
    全日本鍼灸学会雑誌
    2001年 51 巻 5 号 617-622
    発行日: 2001/11/01
    公開日: 2011/03/18
    ジャーナル フリー
    狭義の五十肩のうち、拘縮が無く疼痛が見られるfreezing phaseにあたる症例と、拘縮が進行したfrozenphaseにあたる症例を経験した。現代医学的に病態をとらえ、疼痛の軽減とmuscles pasmの改善を目的として、肩板を構成する肩関節周囲の筋への局所的アプローチにて鍼灸治療を行った。freezing Phaseにおける疼痛は早期に改善した.frozen phaseにおける拘縮は、鍼灸単独では効果が得られにくかった。運動療法を併用したところ、拘縮に伴う苦痛が軽減し、効果的な改善を得た。
  • 松原 裕一, 清水 和弘, 宮本 俊和, 河野 一郎
    日本温泉気候物理医学会雑誌
    2010年 73 巻 2 号 92-100
    発行日: 2010年
    公開日: 2013/09/05
    ジャーナル フリー
     Acupuncture treatment is one of the conditioning methods in the competition field. Athletes who are forced in regularly intensive training often induced deteriorating of condition. Good conditions are adjusted by interaction of immune system, nervous system and endocrine system. Neutrophils and lymphocytes which are blood components prevent infections of the human body in various ways. Intensive training causes an increase of neutrophils, a decrease of lymphocytes and a negative impact on the immune functions. It has been reported that acupuncture stimulation could be involved in the coordination of the immune system. Therefore, acupuncture treatment could be important to keep physical condition and participate physical activity according to the plan without deteriorating of condition. It may be useful not only for athletes but also for the general public who train for the purpose of health and sports enthusiasts. The purpose of this study was to examine the effect of acupuncture stimulation on fluctuation of neutrophils and lymphocytes by the transient high-intensity exercise.
    Method : Twelve healthy men (23.6±O.3 yr [±SE]) participated in this study. Subjects exercised on bicycle ergometer for 60 minutes at 75% of their VO2max. Acupuncture treatment was applied at LU6 (Kongzui), LI 4 (Hegu), ST 36 (Zusanli), and ST 6 (Jiache), for 30 min after the exercise. Blood samples were taken before exercise, immediately after exercise, hourly after exercise until 4 hours and 24 hours after exercise. Leukocyte, neutrophils, lymphocytes, Th cells and Tc cells were measured from the blood samples.
    Result : The neutrophils significantly increased from Post 1h to Post 4h in the both trials (P < 0.05). However the neutrophils was significantly lower in the acupuncture group than in the control group at Post 1h and Post 3h (P < 0.05). The lymphocytes significantly increased from immediately after exercise to Post 24h in the control trial, and increased significantly only at Post 1h to Post 3h in the acupuncture trail (P<0.05). The Th cells significantly decreased from Post 1h to Post 24h in the control trial and decreased significantly only at Post 1h, 2h and 24h in the acupuncture trail (P < 0.05).
    Conclusion : These results suggested that acupuncture stimulation may reduce the increase of neutrophils and the decrease of lymphocyte and Th cells caused by high-intensity exercise. These results indicated that acupuncture stimulation may promote the recovery from high-intensity exercise.
  • 栗林 恒一, 笠原 由紀, 田原 壮平
    全日本鍼灸学会雑誌
    2005年 55 巻 2 号 118-122
    発行日: 2005/05/01
    公開日: 2011/03/18
    ジャーナル フリー
    鍼治療は免疫応答を調節することにより、アレルギー疾患や膠原病などの自己免疫疾患などの治療を行いうると考えられている。しかし、鍼治療のこれらの疾患に対する有効性については、未だ充分には確立されておらず、また、鍼治療が免疫応答を調節するメカニズムについてもほとんど明らかとなっていない。今回、これまでに報告された鍼の免疫性疾患に対する治療効果や、鍼の免疫応答に与える影響について基礎的に検討された論文を紹介するとともに、それらのデータや、我々の実験室で得たデータから、鍼の免疫応答に与える影響についての仮説的なメカニズムを提示したい。
  • 松原 裕一, 宮本 俊和, 河野 一郎
    日本温泉気候物理医学会雑誌
    2010年 73 巻 3 号 191-201
    発行日: 2010年
    公開日: 2013/09/05
    ジャーナル フリー
    Backgrounds : The one of the leading factors of deteriorating condition is upper respiratory tract infections (URTI) in athletes. Athletes who are forced in regularly intensive training often decrease salivary secretory immunoglobulin A (SIgA) which has important role of immune function in the buccal cavity. It causes increase of morbidity risk in URTI. Acupuncture treatment is one of the conditioning methods in the competition field and mainly treated for orthopedic injuries. On the other hands, acupuncture treatment induced increase of natural healing ability which involved immune response, and prevent and treat some diseases. It has been reported acupuncture increase SIgA level. However, the relationship between time course and diagnostic of cold by the acupuncture stimulation effect is still unclear. Thus, the purpose of this measurement is to investigate the effect of acupuncture stimulation on the SIgA during training camp. Furthermore, it is important to investigate questionnaire about diagnostic of cold during and 1 week after training camp, it leads to clear the effect of acupuncture stimulation on the URTI.
    Methods : Eighty subjects men who have auditory difficulties (26.7±0.9 yr[±SE]) participated in this study. The subjects were randomly assigned two groups; acupuncture group and control group. The training camp conducted 3 days and training performed 3 hours each in the morning and afternoon. Acupuncture stimulation was applied at LU 6 (Kongzui), LI 4 (Hegu), ST 36 (Zusanli), and ST 6 (Jiache), for 30 min after dinner. To measure SIgA level, saliva samples were taken 7 times; daytime and evening of first day (Day1(D), Day1(E)), morning, daytime and evening of the second day (Day2(M), Day2(D), Day2(E)), morning and daytime in the third day (Day3(M), Day3(D)). The questionnaire about diagnostic of cold was conducted Day1(D), Day2(M), Day3(M) and 1 week after training camp.
    Results : The secretion rate of SIgA in the control was not significantly changed during training camp. However, the acupuncture group was significantly higher level in the Day2(M) and Day3(M) compared to the Day1(D) (P<0.05). Both control and acupuncture group was significantly higher SIgA concentration in Day2(M) and Day3(M) compared to the Day1(D) (P<0.05), but acupuncture group was significantly higher in the Day3(M) compared to the control. The frequency of diagnostic cold was 1 in the acupuncture group and 4 in the control group. Moreover, 1 week after training camp, 6 in the acupuncture group and 6 in the control.
    Conclusion : Acupuncture stimulation induced significant increase SIgA level during training camp. Moreover, the diagnostic of cold was lower during training camp in the acupuncture group. Therefore, acupuncture stimulation might reduce the risk of the morbidity of the URTI.
  • スモンの自律神経症状におよぼす鍼治療の効果
    矢澤 一博
    日本温泉気候物理医学会雑誌
    1985年 48 巻 4 号 167-181
    発行日: 1985年
    公開日: 2010/08/06
    ジャーナル フリー
    The effects of acupuncture therapy on autonomic nervous complaints were studied. Acupuncture therapy was given to 30 patients with subacute myelo-optico-neuropathy (SMON), and 53.5%, on the average, showed improvement in the autonomic nervous complaints specific to SMON. In seven of these, who had undergone acupuncture therapy for three successive years, a high rate of improvement, 77.3% on the average, was observed, indicating that acupuncture therapy is useful in alleviating autonomic nervous complaints even in the chronic stage. These results suggested an effect of acupuncture on autonomic nervous system.
  • 井上 基浩, 片山 憲史, 北條 達也, 矢野 忠, 勝見 泰和
    体力科学
    2001年 50 巻 1 号 119-128
    発行日: 2001/02/01
    公開日: 2010/09/30
    ジャーナル フリー
    The effects of electrical acupuncture at the patellar tendon and electrical stimulation of the femoral nerve on patellar tendon blood flow were evaluated using laser Doppler flowmetry in anesthetized rats. In most subjects the blood flow in the patellar tendon rapidly decreased for 30 seconds after the start of local electrical acupuncture and then increased above baseline. Changes in blood flow did not necessarily follow changes in arterial blood pressure. Changes in tendon blood flow induced by electrical stimulation of the femoral nerve were similar to those induced by electrical acupuncture at the patellar tendon. Arterial blood pressure and heart rate were not affected by electrical stimulation of the femoral nerve. Phentolamine administration abolished the decreased patellar tendon blood flow seen after initiating electrical acupuncture at the patellar tendon, whereas atropine abolished the increased patellar tendon blood flow seen after terminating electrical acupuncture at the patellar tendon. Furthermore, atropine did not evoke increased blood flow following electrical stimulation of the femoral nerve. These results suggest that the decrease of blood flow seen after initiating electrical acupuncture may be controlled by sympathetic vasoconstrictor nerves and the increase of blood flow following electrical acupuncture may be controlled by cholinergic vasodilator nerves.
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