The ability of Climacodon septentrionalis to immobilize and kill a mycophagous nematode (Aphelenchoides sp.) in vitro is described for the first time. Two isolates produced droplets (20–45 μm in diameter) that formed at the apices of tall, stalked, and branching secretory cells (700–1,500 μm tall). On

% modified malt extract agar, nematodes became enveloped in the droplets, which restricted their ability to move and resulted in complete immobilization and death within several hours of contact. The rate of decomposition of the nematodes varied considerably, with most individuals persisting for weeks whereas others were degraded within several days and appeared to be colonized by dense hyphal growth. This study provides the first documentation of a non-agaricoid fungus producing secretory cells that are able to immobilize nematodes.

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-Benzyl--chloro--mercapto-3 (H)-pyridazinone (1) was heated in ethanol under reflux for 10 hours to form concurrently , -dibenzyldipyridazo [, - : ', '-]-1, -dithiin-1, 6 (H, H)-dione (Ia) (57% in yield) and , -dibenzyldipyridazo [, - : ', '-]-1, -dithiin-1, (H, H)-dione (IIa) (14% in yield). Assignment of the two products to the corresponding structures is established by their physico-chemical constants and chemical behaviors. The concurrent formation of the dipyridazo [, - : ', '-]-1, -dithiin-1, 6 (H, H)-dione and the -1, (H, H)-dione were observed in, not only heating -chloro--mercapto-3 (H)-pyridazinones (1-3) in polar solvent, but warming -mercapto--chloro-3 (H)-pyridazinones (-6) in the presence of potassium carbonate in DMF. For the interpretation of the reaction, keto-thioketo carbenes as active intermediate species and a reversible interconversion among them are suggested on the basis of the fact that there was nonexistence of an equilibrium between the two compounds, such as Ia and IIa, under the reaction condition and a trapping keto-thioketo carbene species as -phenylimino--benzylpyridazo [, -d]-1, 3-dithiol- (H)-one (IVa) (14% in yield) along with the major products, (Ia) and (IIa), was furnished by warming 1 with phenylisothiocyanate in the presence of triethylamine in dry benzene. On the contrary, participation of a reversible interconversion between Ia and IIa, to a considerable extent, with the concurrent formation of them in the case of benzylation of either Ib or IIb, by warming with benzylchloride in the presence of potassium carbonate in DMF at 80°, might not be neglected, because an attempted approach to an equilibrium between Ia and IIa in a similar reaction condition except the use of benzylchloride realized, whereas non-existence of an equilibrium between Ib and IIb in the similar reaction condition was observed.

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The possibility of attenuation of microseismic waves due to the presence of an upward folding of the ocean bottom into the liquid is discussed in this paper. The upward folding of the ocean bottom has been idealized by means of an irregularity in the form of a rectangle intruding into the liquid and the evaluation of the displacement component at any point of the solid medium has been carried out in two stages. First, the change in the incident mode of the surface wave due to the presence of the rectangular irregularity has been determined, and second, the subsequent change of the resulting displacement components due to the termination of the liquid layer and the step change in elevation of the solid medium at the continental margin has been discovered. Finally, numerical calculation has been made to determine the attenuation of the microseismic waves of different periods due to the presence of the rectangular irregularity at the ocean bottom.

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A sample of [³H] tobrarnycin (, 000 Ci/Mole) has been synthetized and incubated with
the bacterial ribosome and its subunits. The results obtained show that this antibiotic has
two types of binding sites. The primary one is probably responsible for the inhibition of
protein synthesis whereas the secondary one is probably related to the misreading and reading
tiirough of the messenger RNA.

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The effect of composition and controlled thermomechanical process parameters on the mechanical properties of HSLA steels is modelled using the Widrow-Hoff's concept of training a neural net with feed-forward topology by applying Rumelhart's back propagation type algorithm for supervised learning, using a Petri like net structure. The data used are from laboratory experiments as well as from the published literature. The results from the neural network are found to be consistent and in good agreement with the experimented results.

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An unsupervised learning technique and an associative memory have been used for encoding weights by a special type of Petri network named Petri neural net for modelling the influence of alloying elements on the final property of the high strength low alloy steel. The combined effects of alloying elements for different strengthening mechanisms is predicted when weights and threshold values are chosen on the basis of metallurgical understanding. The technique is found to be effective to create an associative memory of input-output relations in unknown data sets so that the same can be subsequently be used as a predictive tool.

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Primarily from the point of view of improvement of yield strength due to additions of niobium, titanium and boron in HSLA steels, the experimental steels are divided into five classes. The data are then supplied for learning a Self Organising Map (Kohonen network). It is found that the network with six neurons possesses better capacity of prediction with unknown data. Another effort of clustering the steels according to its major strength contributing mechanisms is also made. But the capacity of the network to cluster unknown data is found to be rather poor and has failed to follow from the metallurgical principles. To avoid this limitation, Learning Vector Quantisation method is adopted to impart a certain amount of supervision in the learning process and it is found that the training pattern of the network attains a good convergence thereby leading to a good predictive ability.

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A boron treated copper bearing HSLA steel containing austenite formers like manganese and nickel, somewhat lower in amount than that in HSLA 100 variety of steel is chosen for the study. The role of thermomechanical processing on the microstructure and mechanical properties of the above steel has been investigated. Differential scanning calorimetric study is carried out for understanding the precipitation behaviour of copper in HSLA steel under the influence of boron. The microstructure of the experimental steel is found to consist of laths of martensites and bainite. MA constituents of ribbon like morphology are observed at the lath boundaries. Higher strength properties of the steel are attributed to the presence of finely distributed precipitates of copper and microalloy carbides.

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Horizontal plate anchors are widely used in civil engineering constructions to resist vertical pulling loads. The available theoretical model suggested by Vesic to estimate the breakout resistance of plate anchors is in significant error, particularly for dense sandy soils. A theoretical model assuming a curved surface of failure through the surrounding soil, to evaluate the ultimate breakout resistance of horizontal plate anchors, has been proposed. It successfully brings out the concept of characteristics relative depth beyond which the breakout factor reaches a constant final value. It is capable of predicting breakout factors for wide range of values of angle of shearing resistance of sand.

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-Amino-6-mercapto-1, 3-dimethyluracil () was prepared by the treatment of , 6-diamino-1, 3-dimethyluracil (1) with liquid and pyridine in a sealed steel tube at 60°C for 20 h. Thiazolo[, -d]pyrimidinediones 3a, were obtained from by cyclization with and AcOH.Under stringent conditions, however, 1 was converted into the , -dihydrodipyrimido[, - : ', '-][1, ]thiazine derivtive a.The structure of a was confirmed by spectral (nuclear magnetic resonance and mass spectra) data and by comparison with a sample which was prepared from and -hydroxy-1, 3-dimethyluracil.Benzylation of a gave 1, 3, , -tetramethyl--benzyl (or p-bromobenzyl)-, -dihydrodipyrimido[, - : ', '-][1, ]thiazine-, , 6, -(1H, 3H, H)-tetrone (, c) and 1, 3, , -tetramethyl--benzyl (or p-bromobenzyl)-, -dihydropyrrolo[3, -d : , -d']dipyrimidine-, , 6, -(1H, 3H, H)-tetrone (6a, ).

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Simultaneous measurements of the total geomagnetic field intensity by the same type of the proton precession magnetometers at two stations in NW Turkey have been taken cooperatively by a research group since December 1970. Up to the end of July 1971 mainly three probable local magnetic changes were observed. It was seen that after a decrease in the local field at a magnetic station (Erdek) a few earthquakes occured at either nearly N or S of that station, and after an increase in the local field an earthquake took place nearly W of the same station. In this paper the data and some results of the first part of observations are given.

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Nine isoquinoline alkaloids belonging to the protoberberine, proaporphine and bisbenzyl-isoquinoline series were isolated from Caryomene olivascens (Menispermaceae). Four compounds are new : (-)--norlimacine (), (-)-caryolivine (6), (+)-1, -dehydro--norlimacusine () and N-formylstepharine (3). The last one is the first N-formyl derivative to be reported in the proaporphine group. Its biogenetic origin is discussed. Structures were established on the basis of 360 MHz (FT) nuclear magnetic resonance measurements and also by chemical correlation in the case of 3.

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In view of the significant role of the water film effect in flow failure for a liquefied sandy deposit, the mechanism of water film generation is numerically studied based on a 1-dimensional model test. The process of water film growth and decay can be simulated to a certain extent by a simple consolidation analysis, which indicates that only a small difference in permeability in layered sand is enough for a water film to develop. A 1 G shaking table test for a two-dimensional slope model with an arc of silt within a saturated sand is then addressed to discuss the dilatancy effect exerted in sheared sand during flow failure. It is possible that, once the water film is formed, the transmission of shear stress through it is interrupted, leaving the sand below free from the dilatancy ; this eventually allows the water film to stay without being absorbed during flow failure. The result of another shaking table test for a trapezoidal slope with horizontal silt seams indicate that water films beneath the seams enable the soil mass above them to laterally flow along water films very gently inclined even after shaking. If a silt seam breaks due to excessive pressure in the water film, it triggers re-liquefaction in the upper sand and leads to further instability.

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One method currently being considered for the disposal of high level radio-active waste is burial in the seabed. When a hot object is buried in soil, the temperature of the soil adjacent to the object is raised and there is transient heat flow away from the object. The rise in the temperature of the soil causes excess pore pressures to be generated and transient pore water diffusion also takes place. A finite element formulation of the coupled heat flow and consolidation problem is presented. The computer implementation of this formulation is found to compare favourably with analytical solutions based on the same physical principles.

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