THE CHEMISTRY OF THE LIPIDS OF POSTHEMOLYTIC RESIDUE OR STROMA OF ERYTHROCYTES

I. CONCERNING THE ETHER-INSOLUBLE LIPIDS OF LYOPHILIZED HORSE BLOOD STROMA

Abstract

1. Two kg. of lyophilized horse blood stroma was prepared and extracted with organic solvents.
2. From the ether-insoluble lipid fraction, palmityl-sphingoniyelin and a glycolipid, which is described under the name of hematoside, were isolated.
3. The cleavage products from both lipids were studied in detail.
ADDENDUM: I . After this paper was submitted, Prof. Dr. E. Klenk had the kindness to send us his detailed papers. According to the report (21), he already noticed that neuraminic acid in paper (19) possessed a methoxyl group. He used, thereafter, the term neuraminic acid, C₁₀H₁₉O₉N, for the non-methoxyl substance which corresponds our prehemataminic acid. Whereas he prefer for the methoxyl-containing acid C₁₁H₂₁O₉N to C₁₀H₁₉O₈N, we take the latter for our hemataminic acid.
2. Though the structural study of hematoside is being continued, it is justified to state that the amino group of prehemataminic acid in the original undegraded lipid is probably substituted by an acyl group, since no amino nitrogen is found in hematoside by Van Slyke's method.