1995 Volume 37 Issue 12 Pages 2794-2798_1
A 37-year-old male was hospitalized due to right lower abdominal pain. He had no history of gastrointestinal polyposis, von Recklinghausen's disease, or multiple endocrine neoplasia type 2b (MEN type2b). Barium enema and colonoscopy were performed and revealed a reddish, slightly elevated lesion in the ascending colon. It was treated by endoscopic mucosal resection. Microscopiccally, there was proliferation of ganglion cells and interlacing bundles of nerve fiber within the lamina propria. Immunohistchemical stains revealed S-1aa protein and neuron-specific enolase to be positive for the lesion. The peculiar findings of this lesion are discussed and literature is reviewed.