2022 Volume 35 Issue 4 Pages 255-261
In Japan, hydroxyapatite (HA) was approved as an artificial bone for dentistry in 1985. Since then, various bone substitutes have been developed and distributed.
However, there are only two bone filling materials that are indicated for bone regeneration based on the placement of the implant body in implant treatment : apatite carbonate granules and octacalcium phosphate (OCP)/collagen complex.
We have previously evaluated bone substitutes that have not been approved for use in implant treatment in cell cultures or animal experiments. This review describes the characteristics and indications of ultra-porous HA granules with excellent new bone formation and biodegradable low-crystal HA/collagen composite sponge. In addition, cases of bone augmentation using these bone substitutes are introduced.
