A Case of Parathyroid Carcinoma with Primary Hyperparathyroidism

Abstract

A case of parathyroid carcinoma with primary hyperparathyroidism was reported.
Man aged twenty-four years complained of increasing pain in the right thigh in the walking. This symptom had been present for past eleven months, recently complained of disturbance of gait.
On examination, there was tenderness in the ritht thigh.
The radiograph of all bones showed demineralization and subperiosteal resorption.
In the long bones the cortex was thinned, while the medullary cavity was correspondingly widened.
The serum calcium varied from 7.7 to 9.1 miliequivalent per liter, the serum phosphorus was within normal limits, and the serum alkaline phosphatase varied from 38.1 to 73.6 Bodansky unit. Urinary calcium and phosphorus excretion increased.
A diagnosis of primary hyperparathyroidism was made, and parathyroidectomy was performed. A encapsulated tumor was found at the left supraclavicular region. It weighed 5.8 grammes and histologically showed appearances of a parathyroid carcinoma.
Four months after operation, biochemistrical examination was within normal limits.
The radiograph of all bones showed calcification.