Abstract
Sixteen extranodal malignant lymphomas (ENML) for the last 16 years have been retrospectively studied. Nine cases were originated in the stomach, one in the duodenum, two in the small intestine, two in the spleen, and two in the thyroid gland. Eleven cases were in stage I, or II, and five in stage IV, in which the invasion to the adjacent organs or tissues was observed. The relation between the histology and the prognosis was not seen, but the prognosis was correlated to the clinical stage. That is, the five-year survival rate was 71% in stage I and II cases, but all stage IV cases died within seven months after surgery. In four of five stage IV cases, the major surgery was performed without preoperative dignosis, but early recurrences were observed and postoperative chemotherapy was not effective. Concerning the therapy of stage IV ENML, it is suggested that the resection and postoperative chemotherapy have to be reconsidered.
