1991 Volume 52 Issue 9 Pages 2042-2046
A 48-year-old man complaining of cough and hemosialemesis was diagnosed to have an endotracheal metastatic lesion from giant mediastinal tumor by minute exploration. Immediately, radiation therapy was started but failed in diminishing the tumor size. The patient developed multimetastasis in the lung and died 2 months later. Autopsy revealed a thyroid tumor and mediastinal tumor continuing to the thyroid one. Histopathologically, the thyroid tumor was papillary carcinoma versus the mediastinal tumor, involving undifferentiated carcinoma in the majority and partially, papillary, adenosquamous cell, and mucoepidermoid carcinomas concomitantly. The part of papillary carcinoma in the mediastinal tumor was thyroglobulin stain-positive, in that it can be considered in this case that thyroid papillary carcinoma transformed into squamous cell, mucoepidermoid, and undifferentiated carcinomas.
