Copiamycin, a New Antifungal Antibiotic Derived from S. Hygroscopicus Var. Chrystallogenes

Abstract

A number of antibiotics have been derived from the organisms belonging to S. hygroscopicus series. A new antifungal agent, copiamycin, was recently isolated in the authors’ laboratory from the mycelium of Streptomyces No. 1898, which, according to the detailed mycological studies, was also found to be a variant of S. hygroscopicus. The name S. hygroscopicus var. chrystallogenes was given to the organism and taxonomic description will be made elsewhere. The present paper deals with the production, isolation, chemical and physical properties and the biological activities of copiamycin.