2023 Volume 65 Issue 10 Pages 2180-2186
We report a case of a 71-year-old man with gastric angiosarcoma. Two round lung tumors were found accidentally on chest CT performed as part of an examination for abnormal liver function. These tumors appeared to be metastatic. Esophagogastroduodenoscopy revealed a red flat, slightly elevated mass in the greater curvature of stomach. Pathological examination of biopsied stomach tissues revealed proliferation of malignant cells. Immunostaining were positive for ERG and CD31. Based on these findings, the patient was diagnosed as having gastric angiosarcoma with lung metastases. The gastric and lung tumor masses diminished in size with the application of chemotherapy with paclitaxel. However, after seven chemotherapy courses, the gastric tumor enlarged and had a purplish-red type 2 tumor-like appearance. Therefore, we changed the chemotherapy regimens; however, it was ineffective. The patient died of serious bleeding in the digestive duct 11 months after the first visit. We encountered a rare case of angiosarcoma in the stomach with multiple distant metastases and found morphological changes in the tumor on conducting esophagogastroduodenoscopy. Further progress in the early diagnosis and treatment of angiosarcoma is needed to improve the prognosis of the affected patients.
