LLLT (LOW REACTIVE LEVEL LASER THERAPY - A CLINICAL STUDY: RELATIONSHIP BETWEEN PAIN ATTENUATION AND THE SEROTONERGIC MECHANISM

Abstract

The relationship between pain attenuation and serotonergic mechanism by low powered laser have been studied. The subjects of 63 cases, having chronic pain and good pain relief were investigated and the change ratio of plasma serotonin was analysed.
On first time laser therapy, the change ratio of plasma serotonin had a stable tendency to give a statistically positive ratio (P<0.001), by the tenth time the ratio had decreased and tended to give a negative ratio (P<0.05) as a result of every other day irradiation.
Furthermore, by every day repeated irradiation, the change ratio in plasma serotonin had altered to a negative ratio.
In this respect, the change ratio of plasma serotonin may be a good clinical indication for LLLT in the assessment of pain attenuation.