2020 Volume 73 Issue 4 Pages 143-150
Objective: The aim of this study was to analyze the surgical outcomes of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for colorectal peritoneal dissemination.
Methods: A total of 127 cases of colorectal peritoneal dissemination were analyzed and the correlation between peritoneal cancer index (PCI), P classification in Japan, and survival rate was determined.
Results: The 5-year survival rate was 36% after CRS and HIPEC. A macroscopic complete resection (CC-0) was possible in 66% of the cases, and the 5-year survival rate for CC-0 cases was 50%. The 5-year survival rate for P1+P2 patients was 59%, and that for P3 patients was 24%. A total of 51% of P3 patients were able to undergo CC-0 resection, and the 5-year survival rate was 40%. In P3 patients with PCI 0-9, 10-19, 20-29, and 30-39, CC-0 resection was performed in 92%, 67%, 20%, and 0% of cases, respectively, and the 3-year survival rates were 53%, 36%, 17%, and 0%, respectively.
Conclusion: Long-term survival can be obtained even in P3 colorectal cancer patients by CRS and HIPEC. It is important to quantify detailed peritoneal dissemination by PCI and to select cases where a CC-0 resection is expected.
