Mechanisms of vomiting in patients with vestibular disorders

Abstract

Acceleration is applied to humans during their postural retention and movement. The equilibrium center receives input from the visual, vestibular, and somatosensory systems, while the vomiting center receives input from the gastrointestinal tract. An input that cannot be regulated by the equilibrium center results in an equilibrium disorder, and an input that cannot be controlled by the vomiting center results in vomiting. Because the vomiting center has greater regulatory capacity than the equilibrium center, a sustained and large input is required to induce vomiting. In the vomiting center, the magnitude of the input from the gastrointestinal tract affects the input from the equilibrium center. During childhood, individuals with a greater gastrointestinal input are thought to develop complex and large neural networks around the two centers, which inhibit vomiting. Individuals with stronger inhibitory functions are more likely to experience vomiting when equilibrium dysfunction occurs. Individuals with stronger inhibitory functions are more likely to experience vomiting when equilibrium dysfunction occurs. Vomiting that occurs in association with vestibular disorders involves equilibrium disorders, afferent input from the gastrointestinal tract to the vomiting center, the neural network around the equilibrium and vomiting centers, and the individual characteristics of the vomiting center.