2001 Volume 47 Issue 7 Pages 443-446
Castleman's disease is a rare, benign lymphoproliferative disorder of unknown origin. The mediastinum is most commonly affected by this disease, followed by the cervical lymph nodes. We report a rare case of Castleman's disease arising in the buccal region. An 81-year-old woman was referred to our hospital in 1989 for further examination and treatment of a slowly-growing left buccal mass. A chicken egg-sized, relatively well-defined painless mass was found in the left buccal region. Smaller stellite masses were also palpable. Computed tomography (CT) revealed a homogenouslyenhanced soft tissue mass in the left buccal region, with expansion to the left infratemporal fossa and pterygomandibular space. The left parotid gland was not involved. A biopsy specimen of the lesion displayed features of Castleman's disease. Immunoserological analyses showed a markedly elevated IgM level. Radiotherapy followed by surgical resection of the lesion was performed. Postoperative follow-up has revealed no signs of recurrence.
