Abstract
The frequency of cognitive impairment among hemodialysis patients is significantly higher than in
the general population. Behavioral and Psychological Symptoms of Dementia(BPSD)are commonly
observed in individuals with dementia, and these symptoms can include agitation, aggression, anxiety,
depression, hallucinations, and sleep disturbances. For elderly hemodialysis patients who have difficulty
with oral administration of drugs, managing BPSD that induce trouble to take rehabilitation can be a
challenging issue. In such situations, the transdermal administration of blonanserin shown to be effective.
The use of blonanserin transdermal patches led to an improvement in the symptoms of BPSD in
an elderly hemodialysis patient and enabled rehabilitation and hemodialysis treatments.