2025 Volume 6 Issue 3 Pages 150-157
Objectives: The aim of this study was to investigate the association between preoperative physical function and life prognosis in patients with chronic limb-threatening ischemia (CLTI).
Material and methods: We retrospectively reviewed 95 patients with CLTI (95 limbs) who underwent preoperative evaluation and subsequent revascularization between 2017 and 2023. Preoperative evaluation was conducted by members of a specialized CLTI team. Multivariate analysis was performed to examine risk factors for death after revascularization.
Results: Of 95 CLTI patients, 65 patients (68%) showed decreased grip strength (male<28 kg, female<18 kg) . During follow-up with a median period of 19 months, 35 patients died, and the 2-year survival rate was 67.3%. Multivariate analysis revealed associations between mortality and decreased grip strength (hazard ratio［HR］10.13; 95% confidence interval［CI］, 1.37-75.19; p=0.024), hypertension (HR 3.26; 95%CI 1.11-9.59; p=0.031) , and contralateral CLTI (HR, 2.22; 95%CI 1.11-4.42; p=0.023).
Conclusions: Decreased grip strength (male<28 kg, female<18 kg) was associated with mortality in CLTI patients. Our findings suggest that grip strength testing should be considered a necessary component of preoperative evaluation in these patients.
