門脈本幹腫瘍塞栓の自然退縮を認めた肝細胞癌の1例

大岡 美彦; 千葉 哲博; 井上 将法; 若松 徹; 齊藤 朋子; 関本 匡; 小笠原 定久; 鈴木 英一郎; 太和田 暁之; 丸山 紀史; 岸本 充; 横須賀 收

doi:10.2957/kanzo.57.178

Case Report

A case of hepatocellular carcinoma with spontaneous regression of a tumor thrombus invading the main portal trunk

Yoshihiko Ooka, Tetsuhiro Chiba, Masanori Inoue, Toru Wakamatsu, Tomoko Saito, Tadashi Sekimoto, Sadahisa Ogasawara, Eiichiro Suzuki, Akinobu Tawada, Hutoshi Maruyama, Takashi Kishimoto, Osamu Yokosuka

Author information

Yoshihiko Ooka
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University
Tetsuhiro Chiba
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University
Masanori Inoue
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University
Toru Wakamatsu
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University
Tomoko Saito
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University
Tadashi Sekimoto
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University
Sadahisa Ogasawara
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University
Eiichiro Suzuki
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University
Akinobu Tawada
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University
Hutoshi Maruyama
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University
Takashi Kishimoto
Department of Molecular Pathology, Graduate School of Medicine, Chiba University
Osamu Yokosuka
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University

Keywords: hepatocellular carcinoma, portal vein tumor thrombus, Vp4, spontaneous regression, transarterial chemoembolization

JOURNAL FREE ACCESS

2016 Volume 57 Issue 4 Pages 178-185

DOI https://doi.org/10.2957/kanzo.57.178

Details

Abstract

We describe a hepatocellular carcinoma (HCC) patient with a spontaneous regression of portal vein tumor thrombus (PVTT) of the main trunk of the portal vein (Vp4). A 63-year-old man with hepatitis C virus infection had been diagnosed with multiple HCC with Vp4 PVTT accompanied by massive ascites. Considering the unfavorable physical condition and liver function, the patient had been recommended to receive the best supportive care. The patient took ursodeoxycholic acid, glycyrrhizin and diuretic but not herbal medicine and was abstained from alcohol entirely. Six months after initial diagnosis, the patient was re-examined in our hospital. Contrast-enhanced computed tomography and ultrasound examination revealed the regression of PVTT but not of intrahepatic lesions associated with HCC. Subsequently, we performed an additional transarterial chemoembolization (TACE) was performed. Six months after the TACE, the patient is alive without recurrence.

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