Abstract
Paralytic ileus is one of the most important systemic complications associated with intracranial diseases such as subarachnoid hemorrhage (SAH), intracerebral hemorrhage (ICH), cerebral infarction (CI) and cerebral contusion (CC). A patient who suffers from intracranial diseases including cerebrovascular strokes has a tendedncy to be complicated by a paralytic ileus.21)22) In this paper, we present 15 cases with intracranial diseases who suffered from paralytic ileus. Indeed, various factors such as a previous history of an abdominal operation, sepsis, trauma, and drugs may contribute to the mechanism of this complication. On the other hand, nimodipine, a kind of calcium antagonist is an effective hypotensive agent without decreasing the cerebral blood flow. But an administration of this agent sometimes causes a paralytic ileus.1)2) Nimodipine were administered for all the patients of our 15 cases with hypertension. It was suggested that an administration of nimodipine was the most significant factor of the paralytic ileus of our patients. Three patients died of paralytic ileus despite the intensive conservative treatments described as below. So we must pay attention to this unexpected complication when we use this agent for those with intracranial diseases.