2024 Volume 52 Issue 2 Pages 111-115
Vascular Ehlers–Danlos syndrome (EDS) is the most serious disease type that results from a type III collagen (COL3A1) gene mutation and causes an aneurysm, arterial dissection, gastrointestinal perforation, and uterine rupture. Here, we describe the case of a 24-year-old man with a family history of Ehlers–Danlos syndrome. Genetic testing revealed a COL3A1 mutation, confirming the diagnosis of vascular Ehlers–Danlos syndrome. Brain magnetic resonance angiography performed during screening revealed a 9-mm left fusiform middle cerebral aneurysm. Cerebral aneurysm clipping was performed via left frontotemporal craniotomy. No intraoperative complications occurred and cerebral aneurysm clipping was performed according to the standard protocol. All treatment options should be analyzed in patients with EDS. Craniotomy for fusiform middle cerebral aneurysms is possible and should be performed when deemed optimal.
