National BioResource Project-Rat and Related Activities

Tadao SERIKAWA; Tomoji MASHIMO; Akiko TAKIZAWA; Ryoko OKAJIMA; Naoki MAEDOMARI; Kenta KUMAFUJI; Fumi TAGAMI; Yuki NEODA; Mito OTSUKI; Satoshi NAKANISHI; Ken-ichi YAMASAKI; Birger VOIGT; Takashi KURAMOTO

doi:10.1538/expanim.58.333

Review

National BioResource Project-Rat and Related Activities

Tadao SERIKAWA, Tomoji MASHIMO, Akiko TAKIZAWA, Ryoko OKAJIMA, Naoki MAEDOMARI, Kenta KUMAFUJI, Fumi TAGAMI, Yuki NEODA, Mito OTSUKI, Satoshi NAKANISHI, Ken-ichi YAMASAKI, Birger VOIGT, Takashi KURAMOTO

Author information

Tadao SERIKAWA
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Tomoji MASHIMO
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Akiko TAKIZAWA
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Ryoko OKAJIMA
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Naoki MAEDOMARI
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Kenta KUMAFUJI
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Fumi TAGAMI
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Yuki NEODA
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Mito OTSUKI
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Satoshi NAKANISHI
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Ken-ichi YAMASAKI
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Birger VOIGT
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
Takashi KURAMOTO
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University

Keywords: bioresource, ENU mutagenesis, NBRP-Rat, phenome project, RI strains

JOURNAL OPEN ACCESS

2009 Volume 58 Issue 4 Pages 333-341

DOI https://doi.org/10.1538/expanim.58.333

Details

Abstract

In order to establish a system to facilitate the systematic collection, preservation, and provision of laboratory rats (Rattus norvegicus) and their derivates, the National BioResource Project-Rat (NBRP-Rat) was launched in July 2002. By the end of 2008, more than 500 rat strains had been collected and preserved as live animals, embryos, or sperm. These rat resources are supplied to biomedical scientists in Japan as well as in other countries. This review article introduces NBRP-Rat and highlights the phenome project, recombinant inbred strains, BAC clone libraries, and the ENU-mutant archive, named the Kyoto University Rat Mutant Archive (KURMA). The future direction of rat resources are also discussed.

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