• A PREDICTION SYSTEM FOR A RELIABLE ESTIMATION OF DRUG METABOLISM AND SAFETY
  Yasushi Yamazoe
  Session ID: PL
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.1.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• QUANTITATIVE CLINICAL PHARMACOLOGY: IMPACT ON DRUG DEVELOPMENT AND CLINICAL PRACTICE
  Lawrence J. Lesko
  Session ID: DL-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.2.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• STRUCTURE AND FUNCTION OF MEMBRANE TRANSPORTERS
  So Iwata
  Session ID: DL-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.3.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• MEMBRANE TRANSPORTERS AND THEIR IMPACT ON DRUG DISCOVERY: TRANSPORTERS OF SUGARS, PEPTIDES AND NUCLEOBASES
  Matthias A. Hediger
  Session ID: DL-3
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.4.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• HOW COULD WE MANAGE THE RISK OF FAILURES AT THE INDUSTRY?
  Tadao suzuki
  Session ID: S1-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.5.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• FAILURE BASED DRUG DESIGN
  Yukio Tada
  Session ID: S1-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.6.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• TO TURN THE FAILURE IN PRECLINICAL STUDIES INTO SUCCESS
  Eiichi Fuse
  Session ID: S1-3
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.7.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• FACTORS LEADING TO ERRONEOUS PKPD INTERPRETATION
  Ryosei Kawai
  Session ID: S1-4
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.8.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• LESSONS LEARNED FROM THE ISSUES IN CLINICAL TRIALS
  Ichimaro Yamada
  Session ID: S1-5
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.9.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• IDENTIFICATION AND CHARACTERIZATION OF CYTOCHROME P450 cDNAs IN CYNOMOLGUS MACAQUE: AN IMPLICATION FOR SPECIES DIFFERENCE BETWEEN MACAQUE AND HUMAN IN DRUG METABOLISM
  Yasuhiro Uno
  Session ID: S2-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.10.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• DRUG-DRUG INTERACTIONS INVOLVING CYTOCHROME P450 INHIBITION AND INDUCTION IN CYNOMOLGUS MONKEYS
  Tatsuyuki Ohtsuka
  Session ID: S2-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.11.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• STUDY ON SPECIES DIFFERENCES OF DRUG METABOLISM IN CHIMERIC MICE WITH HUMAN AND RAT HEPATOCYTES
  Tae Inoue, Tanoue Chiaki, Shunji Kuribayashi, Kazumi Sugihara, Shigeyu ...
  Session ID: S2-3
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.12.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• UTILITY OF CHIMERIC MICE WITH HUMANIZED LIVER FOR PREDICTION OF HUMAN DRUG DISPOSITION
  Sanjeev Kumar
  Session ID: S2-4
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.13.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• SPECIES AND INDIVIDUAL DIFFERENCES OF P450-MEDIATED DRUG METABOLISM
  Hiroshi Yamazaki
  Session ID: S2-5
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.14.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• SYSTEM-DEPENDENT INHIBITION OF CYTOCHROME P450 (CYP) ENZYMES (HUMAN LIVER MICROSOMES VERSUS HEPATOCYTES)
  Andrew Parkinson
  Session ID: S2-6
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.15.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• RECENT FINDINGS IN GENETIC VARIATION IN ASIAN POPULATION AND THEIR TRANSLATION INTO EFFECTIVE THERAPY
  Sang Seop Lee, Su-Jun Lee, Jae-Gook Shin
  Session ID: S3-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.16.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• CURRENT STATUS OF TRANSPORTER SCIENCE AND ITS TRANSLATION TO DRUG PHARMACOKINETICS AND PHARMACODYNAMICS
  Jashvant Unadkat
  Session ID: S3-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.17.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• PREDICTING COVARIATES OF ADME IN DISEASE: GENERAL MODEL REQUIREMENTS FOR TRANSLATION OF IN VITRO DATA TO IN VIVO EXPECTATIONS
  Amin Rostami-Hodjegan
  Session ID: S3-3
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.18.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• NOVEL PATHWAYS AND APPROACHES IN NITRIC OXIDE SIGNALING
  Thomas Michel
  Session ID: S4-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.19.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• NEXT-GENERATION HIGH-THROUGHPUT SEQUENCER AND DNA MICROARRAY AS ADME RESEARCH TOOLS
  Fumiaki Sato, Kazuharu Shimizu
  Session ID: S4-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.20.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• PHARMACOPROTEOMICS (PPX)
  QUANTITATIVE TARGETED ABSOLUTE PROTEOMICS (QTAP) BASED PHARMACOKINETICS, PHARMACODYNAMICS AND TOXICOKINETICS
  Tetsuya Terasaki, Sumio Ohtsuki
  Session ID: S4-3
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.21.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• OBSERVATION OF PROTEIN-DRUG INTERACTION BY IN-CELL NMR SPECTROSCOPY
  Masahiro Shirakawa
  Session ID: S4-4
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.22.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• GPR109A, A G-PROTEIN-COUPLED RECEPTOR FOR NICOTINATE AND THE BACTERIAL FERMENTATION PRODUCT BUTYRATE, FUNCTIONS AS A TUMOR SUPPRESSOR IN COLON
  Vadivel Ganapathy
  Session ID: S5-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.23.0
  CONFERENCE PROCEEDINGS FREE ACCESS
  Download PDF (298K)
• METABOLOMICS REVEALS IN VIVO FUNCTIONS OF TRANSPORTERS
  Yoshikatsu Kanai
  Session ID: S5-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.24.0
  CONFERENCE PROCEEDINGS FREE ACCESS
  Download PDF (175K)
• PHARNACOGENOMICS OF HUMAN ABC TRANSPORTERS: FROM FUNCTIONAL SNP ANALYSIS TO APPLICATION OF SmartAmp2 METHOD IN CLINICAL RESEARCH
  Toshihisa Ishikawa
  Session ID: S5-3
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.25.0
  CONFERENCE PROCEEDINGS FREE ACCESS
  Download PDF (212K)
• Epithelial paracellular barrier-permselectivity, dynamics, and regulation
  Sachiko Tsukita
  Session ID: S5-4
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.26.0
  CONFERENCE PROCEEDINGS FREE ACCESS
  Download PDF (152K)

• Use of stem cells for novel therapeutic interventions
  Hiromitsu Nakauchi
  Session ID: F-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.27.0
  CONFERENCE PROCEEDINGS FREE ACCESS
  Download PDF (329K)
• DIFFERENTIATION OF ES CELLS INTO HEPATOCYTES AND APPLICATION TO PHARMACOKINETIC STUDY
  Tamihide Matsunaga
  Session ID: F-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.28.0
  CONFERENCE PROCEEDINGS FREE ACCESS
  Download PDF (429K)
• PREDICTION OF DRUG METABOLISM IN HUMAN USING CHIMERIC MICE WITH HUMAN HEPATOCYTES
  Kazumi Sugihara, Tae Inoue, Chiaki Tanoue, Aya Horiguchi, Seigo Sanoh, ...
  Session ID: F-3
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.29.0
  CONFERENCE PROCEEDINGS FREE ACCESS
  Download PDF (341K)
• DEVELOPMENT OF A NOVEL CELL CULTURE PLATE AIMED FOR DRUG DISCOVERY SCREENING
  Yoko Ejiri, Masaya Hosoda, Motohiro Fukuda, Kazuaki Nakamura, Norie Mu ...
  Session ID: F-4
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.30.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• For use of human biospecimens in pharmaceutical R&D – the problems and solutions in policy and ethics
  Toru Masui
  Session ID: F-5
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.31.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• IMPACT OF RENAL TUBULAR SECRETION AND REABSORPTION ON RENAL HANDLING OF DRUGS ON THE MARKET
  Hirotaka Ando, Yoshiaki Kitamura, Tomohiro Ando, Hiroyuki Kusuhara, Yu ...
  Session ID: 1-A-9-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.32.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• EFFECT OF A POTENT MATE PROTEIN INHIBITOR, PYRIMETHAMIN ON THE URINARY AND BILIARY EXCRETION OF METFORMIN
  Sumito Ito, Hiroyuki Kusuhara, Yushun Kuroiwa, Chunyong Wu, Yoshinori ...
  Session ID: 1-A-9-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.33.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• EFFECT OF MULTIDRUG AND TOXIN EXTRUSION (MATE1 AND MATE2-K) POLYMORPHISMS ON THE DISPOSITION OF METFORMIN
  Kana Toyama, Atsushi Yonezawa, Masahiro Tsuda, Satohiro Masuda, Ikuko ...
  Session ID: 1-A-9-3
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.34.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• DECREASED RENAL SECRETION OF METFORMIN IN MULTIDRUG AND TOXIN EXTRUSION 1 (Mate1) KNOCKOUT MICE
  Masahiro Tsuda, Tomohiro Terada, Tomoyuki Mizuno, Toshiya Katsura, Jin ...
  Session ID: 1-A-9-4
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.35.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• COMPARISON OF THE OATP-MEDIATED HEPATIC UPTAKE OF DRUGS BETWEEN HUMANS AND PRECLINICAL SPECIES (MONKEYS AND DOGS)
  Yasuyuki Debori, Kazuya Meada, Yoshiaki Kitamura, Hiroyuki Kusuhara, Y ...
  Session ID: 1-A-9-5
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.36.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• 3-DIMENSIONAL QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIPS OF SUBSTRATES FOR OATP1B1 AND OATP1B3 BASED ON THE PHARMACOPHORE ESTIMATION
  Etsuro Watanabe, Noriyuki Yamaotsu, Hiroyuki Kusuhara, Shuichi Hirono, ...
  Session ID: 1-A-10-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.37.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• PREDICTION OF BILIARY CLEARANCE OF HMG-COA REDUCTASE INHIBITORS USING SANDWICH CULTURED RAT HEPATOCYTES
  Takao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda, Yuichi Sugiyama
  Session ID: 1-A-10-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.38.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• VALIDATION OF SANDWICH-CULTURED HUMAN HEPATOCYTES AS IN-VITRO MODEL BY QUANTITATIVE EXPRESSION PROFILE OF TRANSPORTER AND P450 ENZYME PROTEINS
  Hirotaka Kawakami, Sumio Ohtsuki, Olaf Schaefer, Yuki Katsukura, Thoma ...
  Session ID: 1-A-10-3
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.39.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• COMPARATIVE FUNCTIONAL CHARACTERIZATION OF NOVEL HUMAN RIBOFLAVIN TRANSPORTERS, hRFT1 AND hRFT2
  Yoshiaki Yao, Atsushi Yonezawa, Hiroki Yoshimatsu, Toshiya Katsura, Ke ...
  Session ID: 1-A-10-4
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.40.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• INVOLVEMENT OF L-TYPE AMINO ACID TRANSPORTER 1 IN THE OUTER BLOOD-RETINAL BARRIER TRANSPORT OF L-LEUCINE
  Atsushi Yamamoto, Shin-ichi Akanuma, Masanori Tachikawa, Ken-ichi Hoso ...
  Session ID: 1-A-10-5
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.41.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• L-PROLINE EFFULUX TRANSPORT ACROSS THE INNER BLOOD-RETINAL BARRIER
  Daisuke Yoneyama, Yumiko Shinozaki, Masatoshi Tomi, Shin-ichi Akanuma, ...
  Session ID: 1-A-11-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.42.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• DUAL FUNCTIONAL CHARACTERISTICS OF HUMAN AQUAPORIN 10 FOR SOLUTE TRANSPORT
  Megumi Ishii, Kin-ya Ohta, Takahiro Katano, Kimihiko Urano, Jun Watana ...
  Session ID: 1-A-11-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.43.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• INHIBITION OF PROSTAGLANDIN E2 ELIMINATION VIA BLOOD-BRAIN BARRIER BY CEPHALOSPORINS INTERACTING WITH MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 4
  Shin-ichi Akanuma, Shingo Ito, Sumio Ohtsuki, Ken-ichi Hosoya, Tetsuya ...
  Session ID: 1-A-15-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.44.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• QUANTITATIVE TARGETED ABSOLUTE PROTEOMICS (QTAP) FOR MEMBRANE TRANSPORTERS AT HUMAN BLOOD-BRAIN BARRIERS
  Yasuo Uchida, Yuki Katsukura, Chiemi Ikeda, Sumio Ohtsuki, Junichi Kam ...
  Session ID: 1-A-15-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.45.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• THE HUMAN BLOOD-BRAIN BARRIER IN VITRO MODEL (hCMEC/D3) EXPRESSES FUNCTIONALLY ACTIVE ORGANIC CATION/PROTON ANTIPORTER FOR CNS-ACTING CATIONIC DRUGS
  Takashi Okura, Keita Shimomura, Sayaka Kato, Pierre-Oliver Couraud, Ma ...
  Session ID: 1-A-15-3
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.46.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• MULTIPLE ORGANIC ANION TRANSPORTERS INVOLVED IN BLOOD-BRAIN BARRIER TRANSPORT
  Mari Miyajima, Hiroyuki Kusuhara, Hiroshi Kodaira, Yuichi Sugiyama
  Session ID: 1-A-15-4
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.47.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• INVESTIGATION OF THE IMPORTANCE OF MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 4 (MRP4) IN THE BLOOD-BRAIN BARRIER
  Kayoko Kanamitsu, Hiroyuki Kusuhara, Kenji Takeuchi, Yuichi Sugiyama
  Session ID: 1-A-15-5
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.48.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• EZRIN HAS A KEY ROLE IN THE EXPRESSION PROFILE OF MRP2 ALONG THE INTESTINAL TRACT
  Takafumi Nakano, Shuichi Sekine, Kousei Ito, Toshiharu Horie
  Session ID: 1-A-16-1
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.49.0
  CONFERENCE PROCEEDINGS FREE ACCESS
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• SMALL GTP-BINDING PROTEIN RAB8 REGULATES THE INTESTINAL ABSORPTION OF SUBSTRATES FOR SLC INFLUX TRANSPORTERS (PEPT1, SGLT1) IN VIVO
  Tomoko Sugiura, Yasuhito Nakadera, Takashi Sato, Akihiro Harada, Norit ...
  Session ID: 1-A-16-2
  Published: 2009
  Released on J-STAGE: November 26, 2009
  
  DOIhttps://doi.org/10.14896/jssxmeeting.24.0.50.0
  CONFERENCE PROCEEDINGS FREE ACCESS
  Download PDF (327K)