Annual Meeting of the Japanese Society of Toxicology

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The 36th Annual Meeting of the Japanese Society of Toxicology

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Organ Toxicity

Roles of MAP kinase, ERK, and intracellular calcium in oxidative stress injury induced by cisplatin in renal epithelial cells

Yoshiko Kawai, Yukihiro Ohno, Munekazu Gemba

Session ID: O-43
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3043.0

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Enterobacteria-FGF system regulates hepatic bile acid levels

Masaaki Miyata, Yuki Takamatsu, Yasushi Yamazoe

Session ID: O-44
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3044.0

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Increased expression of brain-derived neurotrophic factor gene during development of rat liver hypertrophy induced by antihyperlipidemic agent, clofibrate

Kiyomitsu Nemoto, Masanori Mizukami, Midori Yoshida, Akiyoshi Nishikaw ...

Session ID: O-45
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3045.0

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AhR dependent cell cycle regulation in BHP induced rat lung carcinomas

Yasuko Kobayashi, Tomoko Muto, Kenta Ishida, Masaya Motohashi, Kai Ima ...

Session ID: O-46
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3046.0

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Liver hypertrophy and gene expression in rats administered phenobarbital and clofibrate

Shogo Ozawa, Toshie Gamo, Wataru Habano, Midori Yoshida, Akiyoshi Nish ...

Session ID: O-47
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3047.0

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Mechanism, Metabolism

Effects of novel quinolone antibacterial agents DC-159a and DX-619 on the articular cartilage of juvenile rats

Koichi Goto, Takami Suzuki, Koichi Yabe, Yuri Yamaguchi, Toshimasa Jin ...

Session ID: O-48
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3048.0

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Expression of aryl hydrocarbon receptor in human bone tissues

Yasuhiro Miki, Shuko Hata, Shuji Nagasaki, Takashi Suzuki, Hironobu Sa ...

Session ID: O-49
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3049.0

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Effects of L-type neutral amino acid transporter inhibitor on amino acid uptake in human gastric cancer cells.

Naohiko Anzai, Ai Yamanishi, Daisaku Miura, Sirirat Amonpatumrat, Hito ...

Session ID: O-50
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3050.0

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A Possible Mechanism for the Decrease in Serum Thyroxine Level by 4-OH-2,2',3,4',5,5',6-Heptachlorobiphenyl in Mice

Yoshihisa KATO, Koichi HARAGUCHI, Makiko KUBOTA, Nobuyuki KOGA, Shizuo ...

Session ID: O-51
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3051.0

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Effect of dietary constituents and environmental chemicals on the development of liver cytochrome P450 in rats

Miyuki ARAI, Kazumi SUGIHARA, Shigeyuki KITAMURA, Shigeru OHTA

Session ID: O-52
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3052.0

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Gene expression profiling related to hepatic metabolizing enzymes in transgenic rats expressing human growth hormone gene

Jun HIRAO, Noriyo NIINO, Shingo ARAKAWA, Shingo SHIBATA, Yosuke ANDO, ...

Session ID: O-53
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3053.0

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A possible cause of high expression of CYP1A in ungulates

Wageh Sobhy, Yoshinori Ikenaka, Kentaro Sakamoto, Shoichi Fujita, Mayu ...

Session ID: O-54
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.3054.0

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Poster presentations

Organ Toxicity, Metabolism, Method, etc.

The influence on clinical pathology evaluation by the difference between early and late phase blood in each collection from the abdominal aorta in rats.

Tatsuya ITO, Yukihito MIURA, Hideki TSUTSUMI, Ryouta SAITO, Chiyomi KU ...

Session ID: P-1
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4001.0

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Establishment of plasma levels of blood biochemistry in growth period of Japanese macaque

Harumi Shidara, Hirosi Koie, Shunsaku Iwaki, Tsuneo Sato, Kiichi Kanay ...

Session ID: P-2
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4002.0

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Estradiol inhibits skeletal development in zebrafish embryos

Hironobu Katsuyama, Shigeko Fushimi, Masafumi Tomita, Yoko Watanabe, K ...

Session ID: P-3
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4003.0

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Methanol-Induced Visual Disturbance in Cynomolgus Monkeys

Yuichi Tsuda, Kiyohito Fujita, Kyohei Sugimoto, Kazuya Sekiguchi, Kohs ...

Session ID: P-4
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4004.0

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Methanol-Induced Hepatorenal Toxicity in Cynomolgus Monkeys

Kiyohito Fujita, Yuichi Tsuda, Kyohei Sugimoto, Takahiro Tanaka, Emiko ...

Session ID: P-5
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4005.0

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Serum ornithine carbamyltransferase in the detection of hepatic mitochondrial injury

Hiroshi Murayama, Masaki Ikemoto, Masaru Hamaoki

Session ID: P-6
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4006.0

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The threshold dose for liver tumor promoting effects of dicyclanil in ICR mice

Meilan Jin, Yasuaki Dewa, Masaomi Kawai, Jihei Nishimura, Yukie Saegus ...

Session ID: P-7
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4007.0

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Effects of fenofibrate on plasma and hepatic tranasaminase activities and hepatic transaminase gene expression in rats

Akio KOBAYASHI, Yusuke SUZUKI, Kazuma KONDO, Hideaki YOKOYAMA, Shinich ...

Session ID: P-8
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4008.0

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Changes in plasma concentration of osteopontin in rat acute hepatic injury

Takuya Matsuyama, Kazumi Ito, Kazuyoshi Kumagai, Tomoe Tanimoto, Takak ...

Session ID: P-9
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4009.0

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Effects of morphine hydrochloride on respiratory function measured by whole body plethysmography (Comparison evaluation of unanesthetized/unrestrained cynomolgus monkeys and rats)

masakazu imaizumi, kazuaki sasaki, chengjun ma, hiroizumi yamanaka, ya ...

Session ID: P-10
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4010.0

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Lung function dynamics for noninvasive severity evaluation of lung fibrosis in rats

Kyu-Hyuk Cho, Kyuhong Lee, Young-Su Yang, Mi-Jin Yang, Jeong-Doo Heo, ...

Session ID: P-11
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4011.0

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Effects of drugs on respiratory function in conscious and unrestrained rats: Evaluation with using whole body plethysmography

Yosuke NUMATA, Yoshiki DEGUCHI, Rika ANRAKU, Asako TAMAI, Tetsuya YOSH ...

Session ID: P-12
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4012.0

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Pulmonary emboli and dose-related impairment of cardiopulmonary function by the intravenous injection of precipitated calcium salts in anesthetized rats

Shigeki Toyoshima, Osamu Sawamoto, Takayoshi Nakagawa, Masanobu Suzue, ...

Session ID: P-13
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4013.0

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Establishment of Assay Method for hERG Channel Trafficking by Flowcytometry

Nobuya Ishiharada, Hajime Morimoto, Yuki Inoue, Katsumi Morishita

Session ID: P-14
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4014.0

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Establishment of a line of SPORTS (Spontaneously-Running-Tokushima-Shikoku) rats that form left atrial thrombi

Takamasa Ohnishi, Keisuke Izumi, Yutaka Nakaya, Fumiko Hisaoka

Session ID: P-15
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4015.0

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Establishment of hERG screening assay using automated patch clamp system.

Masaki Honda, Takehito Isobe, Ryuichi Komatsu, Yuichiro Yamada, Kazuya ...

Session ID: P-16
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4016.0

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Protective effects of thiamine in STZ-induced diabetic cardiomyopathy

Yuka Kohda, Hisashi Shirakawa, Kazuhiko Yamane, Kaoru Otsuka, Tatsuji ...

Session ID: P-17
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4017.0

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Urinary renal papillary antigen-1(RPA-1) is a sensitive biomarker for gauging collecting duct responsiveness to a vasopressin V₂ agonist in rats

Hajime TABATA, Shunji NAKATSUJI, Daisuke SASAKI, Jiro SEKI, Yuji OISHI ...

Session ID: P-18
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4018.0

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Evaluation of Biomarkers for Renal Toxicity in Rats

Naomichi SAKUTA, Yasuyuki OONISHI, Chie HIRATANI, Makoto TSUNEMI, Naoa ...

Session ID: P-19
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4019.0

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Comparison of renal lesions induced by 4-ethylmorpholine and 2-(di-n-butylamino) ethanol in rats – Immunohistochemical localization of aquaporin

Tomomi MORIMURA, Fumiaki KUMAGAI, Mami FURUYA, Hiroyasu KATO, Kenji US ...

Session ID: P-20
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4020.0

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Evaluation of urine biomarkers of nephrotoxicity in rats following exposure to gentamicin and anti Thy-1 antibody

Sho Akai, Hiromi Suzuki, Taeko Hasegawa, Ryota Saito, Tomomi Soushin, ...

Session ID: P-21
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4021.0

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Utility as the nephrotoxicity marker of Cystatin C in the rat

Taeko Hasegawa, Ryota Saito, Hiromi Suzuki, Sho Akai, Tomomi Soushin, ...

Session ID: P-22
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4022.0

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Morphological changes of the brain and central nervous system signs due to NMDA receptor antagonist

Motohiro Shiotani, Kyoko Nakano, Ikuo Mori, Norio Akaogi, Satoru Hosok ...

Session ID: P-23
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4023.0

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Aberrant neuronal cell distribution for detection of developmental neuronal toxicants: analysis of the distribution of calbindin-expressing cerebellar Purkinje cells.

YUKIE SAEUGSA, HITOSHI FUJIMOTO, Gye-Hyeong WOO, MASAOMI KAWAI, SAYAKA ...

Session ID: P-24
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4024.0

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A case of cataract was detected in rats with repeat oral administration of Hexachlorophene.

Atsuko HAISHIMA, Yutaka KOMATSU, Naofumi TAKAHASHI, Hideaki FUJIE, Yas ...

Session ID: P-25
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4025.0

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Effects of restricted feeding on fetal and placental development in pregnant rabbits

Tetsuya Matsuoka, Yasumoto Mizoguchi, Ryo Kamata, Ema Otsuka, Hiroyasu ...

Session ID: P-26
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4026.0

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Examination of relative numerical rating scale for macroscopic observation of skin reactions

yasushi yamada, ikuko asano, tooru toyoshi, kouhei kyuki

Session ID: P-27
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4027.0

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Postnatal effects of rat testis following in utero exposure to di(n-butyl) phthalate

Kenta Ishida, Masaya Motohashi, Kai Imai, Yasuko Kobayashi, Tomoko Mut ...

Session ID: P-28
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4028.0

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Evaluation of ovarian pathological changes and toxicity for female fertility by atrazine in 2- or 4-week repeated dose oral toxicity study and fertility study in female rats.

Hiroshi Shibayama, Takashi Kotera, Yasuhiko Shinoda, Tomohiko Hanada, ...

Session ID: P-29
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4029.0

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Male-related genetic malformation and function of reproductive organs in Japanese White rabbits

Dai YAMAMOTO, Einosuke TANI, Yumi WAKO, Tomonari MIYAZAKI, Nobuhito HO ...

Session ID: P-30
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4030.0

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Study about anesthetization of rat fetuses with transplacental treatment of pentobarbital sodium

Mika Senuma, Hiromasa Takashima, Yuka Yoshida, Katsuhiko Saegusa, Ryo ...

Session ID: P-31
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4031.0

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A selective beta1-adrenergic receptor antagonist ameliorates morphological changes of the aortic arch induced by a nonselective beta-adrenergic receptor agonist in rabbit fetuses

Yuko Sakai, Akinobu Okada, Rika Hirota, Seiki Matsuo, Shin Ito, Michio ...

Session ID: P-32
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4032.0

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Environmental epigenomic data are useful for the elucidation of developmental toxicity by chemicals

Tohru Shibuya, Tohru Shibuya

Session ID: P-33
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4033.0

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Testicular damage and spermatotoxicity of 5-methoxy-N,N-dimethyltryptamine in mice

Kuniaki Tayama, Tomoko Fujitani, Yoshimitsu Sakamoto, Hiroshi Ando, Yo ...

Session ID: P-34
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4034.0

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Induction of morphologically abnormal sperm in male rats after single oral treatment with 4,6-dinitro-o-cresol

Ken Takahashi, Satoshi Akema, Satoru Yamaguchi, Ryoichi Ohtsuka, Makio ...

Session ID: P-35
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4035.0

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Recent Requirements and Trends for Developmental and Reproductive Toxicity Studies for Human Therapeutic Monoclonal Antibodies in Cynomolgus Monkeys

Satoru Oneda, Norbert Makori, Narine Lalayeva, Akihiro Arima, Yojiro O ...

Session ID: P-36
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4036.0

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Evaluation for ovarian toxicity of MEHP using rat cultured ovarian follicles: MEHP-induced PCOS (Polycystic Ovary Syndrome) like changes in ovarian follicles

Hiroshi Inada, Kazuhiro Chihara, Chiharu Fukuda, Yumi Tateishi, Juki K ...

Session ID: P-37
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4037.0

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Evaluation of Immune-function by Antibody-Production Test and Cytokine Profile

Hiroyuki KOMATSU, Masanori SAKAGUCHI, Kumiko KITTA, Shigekazu SHIMIZU, ...

Session ID: P-38
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4038.0

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