Effective Intravenous Thrombolytic Therapy in a Patient with Cerebral Infarction Associated with Left Atrial Myxoma

Mayumi Abe; Ai Kohama; Takahiro Takeda; Akimi Ishikawa; Yuichiro Yamada; Yasuhiro Kawase; Yosuke Ishii; Ryuzo Bessho; Yoshiharu Oaki; Shoji Haruta; Takashi Ohashi

doi:10.2169/internalmedicine.50.5545

CASE REPORTS

Effective Intravenous Thrombolytic Therapy in a Patient with Cerebral Infarction Associated with Left Atrial Myxoma

Mayumi Abe, Ai Kohama, Takahiro Takeda, Akimi Ishikawa, Yuichiro Yamada, Yasuhiro Kawase, Yosuke Ishii, Ryuzo Bessho, Yoshiharu Oaki, Shoji Haruta, Takashi Ohashi

Author information

Mayumi Abe
Department of Neurology, Tokyo Women's Medical University, Yachiyo Medical Center, Japan
Ai Kohama
Department of Neurology, Tokyo Women's Medical University, Yachiyo Medical Center, Japan
Takahiro Takeda
Department of Neurology, Tokyo Women's Medical University, Yachiyo Medical Center, Japan
Akimi Ishikawa
Department of Cardiology, Tokyo Women's Medical University, Yachiyo Medical Center, Japan
Yuichiro Yamada
Department of Cardiology, Tokyo Women's Medical University, Yachiyo Medical Center, Japan
Yasuhiro Kawase
Department of Cardiovascular Surgery, Nippon Medical School Chiba Hokusoh Hospital, Japan
Yosuke Ishii
Department of Cardiovascular Surgery, Nippon Medical School Chiba Hokusoh Hospital, Japan
Ryuzo Bessho
Department of Cardiovascular Surgery, Nippon Medical School Chiba Hokusoh Hospital, Japan
Yoshiharu Oaki
Department of Pathology, Nippon Medical School Chiba Hokusoh Hospital, Japan
Shoji Haruta
Department of Cardiology, Tokyo Women's Medical University, Yachiyo Medical Center, Japan
Takashi Ohashi
Department of Neurology, Tokyo Women's Medical University, Yachiyo Medical Center, Japan

Keywords: cerebral infarction, myxoma, intravenous thrombolytic therapy, recombinant tissue plasminogen activator (rt-PA)

JOURNAL OPEN ACCESS

2011 Volume 50 Issue 20 Pages 2401-2405

DOI https://doi.org/10.2169/internalmedicine.50.5545

Details

Abstract

A 70-year-old man presented with sudden onset of global aphasia and right hemiplegia. Brain MRI revealed occlusion of the left middle cerebral artery. He was diagnosed as having a hyperacute cerebral infarction. Intravenous thrombolytic therapy was started, and the neurological symptoms were resolved after 11 h. Echocardiography showed a mobile mass in the left atrium, suspicious of a myxoma. The tumor was resected and pathologically diagnosed as a myxoma. In this patient, intravenous thrombolytic therapy was effective, and no adverse effects were observed. This suggests that, even with complications of myxoma, thrombolytic therapy can be considered if there are no contraindications.

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