Stomato-pharyngology
Online ISSN : 1884-4316
Print ISSN : 0917-5105
ISSN-L : 0917-5105
Original Articles
Carcinosarcoma of the parotid gland: a case report
Nozomi TakahashiKenichi TakanoTsuyoshi OkuniMakoto KuroseAtsushi KondoTetsuo Himi
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JOURNAL FREE ACCESS

2016 Volume 29 Issue 1 Pages 127-132

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Abstract

 A carcinosarcoma of the head and neck area having both carcinomatous and sarcomatous element is extremely rare. We report herein on the case of a 40-year-old woman with a carcinosarcoma of the right parotid gland. She had noticed enlargement of her right parotid gland from 20 years previously, but was not admitted to any hospital. After rapid enlargement of the tumor for a few months, she presented at our hospital. Enhanced computer tomography showed a 30 mm tumor containing caltification, and uptake of FDG-PET (SUVmax was 11.5). Fine-needle aspiration biopsy showed a class V tumor. We conducted a total right parotidectomy and radical right neck dissection for a malignant tumor. Histological examination showed carcinosarcoma, which contained ductal carcinoma as a cartinomatous component and osteosarcoma as a sarcomatous component. This tumor also contained an area like a pleomorphic adenoma, so it was thought to have arisen from the pleomorphic adenoma. Because this tumor is very malignant and has a high frequency of recurrence and metastasis, the patient underwent postoperative radiation therapy (60Gy). Despite achieving a negative surgical margin, metastasis was seen at the sacral spine at one year and 6 month after resection, so she underwent radiation theraphy of the spine (45Gy). She underwent chemotherapy at another hospital, but showed new metastasis. In the literature in Japan, carcinosarcoma of the head and neck area has been reported in 20 other cases. We discuss this tumor with a review of the literature.

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© 2016 Japan Society of Stomato-pharyngology
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