Abstract
We previously reported that 4,237 of 33,063 single nucleotide polymorphism (SNP) markers genotyped by commercial
SNP chips were monomorphic in Japanese Black fattened steers slaughtered at carcass market in Hyogo prefecture. Here we
investigated their distribution and extracted their neighboring genes. Genomic regions were detected as candidate homozygous
regions where ≥ 2 of these SNPs were consecutively located, and the genes located within the regions were extracted. The 672
homozygous regions detected were widely distributed throughout the genome. The 608 extracted genes included ones previously
studied as candidate genes for the degree of marbling in Japanese Black cattle. Gene ontology enrichment analysis (GO analysis) of
the extracted genes found many significant GO terms related to lipids and lipid metabolism (P <0.05). Network analysis of the
genes belonging to the significant term“ nucleotide binding (GO: 000166)” in the STRING database suggested several connections
(edges) among the genes. The results could be useful to characterize the Japanese Black cattle, especially the Hyogo subpopulation.
