Clinical features of colorectal mucinous and poorly differentiated adenocarcinomas; study concept of a propensity score analysis in a pooled data of 5530 patients

Mitsuro Kanda; Koji Oba; Hiromichi Maeda; Toru Aoyama; Michitaka Honda; Kosuke Kashiwabara; Junichi Sakamoto; Sotaro Sadahiro; Shigetoyo Saji; Chikuma Hamada; Takaki Yoshikawa

doi:10.4993/acrt.24.52

Mitsuro Kanda, Koji Oba, Hiromichi Maeda, Toru Aoyama, Michitaka Honda, Kosuke Kashiwabara, Junichi Sakamoto, Sotaro Sadahiro, Shigetoyo Saji, Chikuma Hamada, Takaki Yoshikawa

Author information

Mitsuro Kanda
Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine
Koji Oba
Department of Biostatistics, School of Public Health, Tokyo University Graduate School of Medicine
Hiromichi Maeda
Cancer Treatment Center, Kochi Medical School Hospital
Toru Aoyama
Department of Surgery, Yokohama City University
Michitaka Honda
Department of Disaster Medicine, Fukushima Medical University
Kosuke Kashiwabara
Department of Biostatistics, School of Public Health, Tokyo University Graduate School of Medicine
Junichi Sakamoto
Tokai Central Hospital
Japanese Foundation for Multidisciplinary Treatment of Cancer
Sotaro Sadahiro
Department of Surgery, Tokai University
Shigetoyo Saji
Japanese Foundation for Multidisciplinary Treatment of Cancer
Chikuma Hamada
Faculty of Engineering, Tokyo University of Science
Takaki Yoshikawa
Department of Gastrointestinal Surgery, Kanagawa Cancer Center

Keywords: Colorectal cancer, Mucinous adenocarcinoma, Poorly differentiated adenocarcinoma, Prognosis, Propensity score analysis

JOURNAL FREE ACCESS

2016 Volume 24 Issue 2 Pages 52-53

DOI https://doi.org/10.4993/acrt.24.52

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Abstract

The prognostic relevance of the mucinous subtype of colorectal cancer is still controversially discussed. We designed a large-scale cohort study with a propensity score matching to evaluate the impact of mucinous subtype on postoperative survival, recurrent patterns and chemo-sensitivity in patients with colorectal cancer using the integrated database of three phase III clinical trials. We introduce a study concept and present preliminary results of an overview of the total individual patients’ data here.

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