Crystal Structure of Minoxidil

Abstract

The title compound, C₉H₁₅N₅O, is an antialopecia agent. The crystal belongs to space group P2₁ with cell dimensions a = 9.3799(5) , b = 8.3319(4), c = 12.9984(7)Å and β = 90.191(3)°. The final R value is 0.092. There are two crystallographically independent molecules in an asymmetric unit. They adopt significantly different conformations. The hybridization states of the nitrogen atoms in piperidine rings are markedly different in these molecules.