Structure of Guanethidine Monosulfate

Abstract

The crystal of the title compound, C₁₀H₂₂N₄·H₂SO₄, belongs to space group Pn with the cell dimensions a = 7.131(4), b = 12.969(6), c = 8.068(4)Å, and β = 110.32(3)°. The final R value is 0.063. The azocane ring adopts a boat-chair conformation. In a molecule, the N atom of the azocane ring and one of the N atoms of the guanidine group are bridged by a sulfate ion through a hydrogen bond. Hence, the ethylguanidine group takes a folded conformation. The ethylguanidine occupies an equatorial position of the ring.