Crystal and Molecular Structure of 3,5-Dicarbethoxy-2,6-dimethyl-4-(4′-methoxy)phenyl-1,4-dihydropyridine

Abstract

1,4-Dihydropyridines (DHP) are known for their action as calcium channel blockers and are used for treatment of various cardiovascular diseases. The title compound was synthesized following the classical Hantzsch synthesis. The compound crystallizes in monoclinic crystal class in the space group P2₁/n with cell parameters a = 9.744(3)Å, b = 7.460(2)Å c = 26.662(5)Å, β = 98.34(2)°, Z = 4. The structure adopts a flat boat conformation.