Structure of Fipexide Hydrochloride Monohydrate

Abstract

The crystal of the title compound, C₂₀H₂₁ClN₂O₄·HCl·H₂O, belongs to space group Pccn with cell dimensions a = 30.76(1), b = 11.795(4), and c =11.524(4)Å. The final R value is 0.051. The title molecule as a whole takes an extended conformation with the benzodioxole and chlorophenyl groups being placed on opposite sides with respect to the line through the two nitrogen atoms in the piperazine ring. The dioxole moiety adopts a slightly puckered envelope conformation.