Neurogenic bladder in central nervous system dysfunction

Abstract

Although micturition reflex is spino-bulbo-spinal reflex, because several higher micturition centers located above brainstem regulate micturition reflex, lower urinary symptoms are common in central nervous system disorders including neurodegenerative disease. It is well known that lower urinary tract symptoms are common in Parkinson’s disease. In this symposium, I will discuss how to treat lower urinary tract symptoms in Parkinson’s disease based on recently published guideline. Lower urinary tract dysfunctions are also prevalent and severe in multiple system atrophy which is usually difficult to differentiate from Parkinson’s disease in the early stage. I will discuss the characteristic features of lower urinary tract dysfunction in multiple system atrophy and utility of measuring post-void residual in differentiating Parkinson’s disease from multiple system atrophy.