2020 Volume 57 Issue 2 Pages 130-133
Neuronal intranuclear inclusion disease (NIID) is a rare progressive neurodegenerative disorder characterized by eosinophilic hyaline intranuclear inclusions in neuronal and somatic cells. Clinically the disease occurs in adult with any combination of progressive dementia, cerebellar ataxia and motor-sensory and autonomic neuropathy. Bladder dysfunctions are occurred about 30 % in sporadic cases and 60% in familial cases. The results of urodynamic study showed that bladder sensory dysfunction and underactive detrusor at first. The results of urodynamic study showed that bladder sensory disorder and detrusor overactivity in the second examination. NIID might be caused by peripheral and central nervous system dysfunction. For managing bladder dysfunction in neurologic patients including NIID, it is important not only to address functional incontinence due to dementia and immobility. Thus, checking post-void residual (PVR) is recommended for treatments.
